The invention relates to the technical field of pharmaceutical preparations, and discloses a
sodium butyrate enteric-coated and sustained-release pellet
capsule and a preparation method thereof.The
capsule comprises, by weight, 0.55%-0.88% of
sodium butyrate raw materials, 0.55%-0.88% of filling agents, 0.35%-0.88% of binding agents, 0.20%-0.30% of lubricating agents, 0.20%-0.30% of
enteric coating materials, 0.20%-0.30% of pigments, 0.20%-0.30% of solvents, 0.20%-0.30% of dispersion media, 0.20%-0.30% of 40%-46% of a filling agent; 9%-10% of an
adhesive; 1%-1.2% of a
lubricant; 23%-28% of an
enteric coating material; 0.07%-0.09% of a
pigment; 7%-9% of a
solvent; 5-10% of a dispersion medium; 2%-6% of a release
regulator; due to the design of enteric
solubility, the
capsule can release
medicine in the intestinal tract after passing through the
stomach, the
medicine can be slowly and continuously released in the body, the
curative effect is improved, side effects are reduced, it is ensured that the
medicine cannot be damaged in
gastric acid, meanwhile, turmeric and
carthamin yellow in
pigment can bring warm properties to the capsule, and the capsule has the advantages of being free of toxic and side effects, safe and reliable. The cold and cool feeling in the body can be balanced, and the cold and cool symptom of the
stomach can be relieved.