35 results about "Sodium butanoate" patented technology

A nutraceutical composition, consisting of Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.

Disclosed are a feed additive for improving the ovulation rate and litter size of sows, a preparation method therefor, and a use thereof. The feed additive is composed of three short-chain fatty acid salts, which are respectively sodium acetate, sodium propionate, and sodium butyrate. Sow feed contains the above feed additive, and the amount of the feed additive that is added is 0.1%-1% of the total weight of the basic daily diet of a sow. The feed additive of the present invention has a simple preparation process and low production costs and has the effect of significantly improving the ovulation rate and litter size of sows.

The present invention provides a compound feed for freshwater fish and a preparation method thereof, comprising the following raw materials in parts by weight: 39-44 parts of corn protein powder, 22-34 parts of cottonseed protein powder, 5.4-9.2 parts of black soldier fly larva powder, 11-23 parts of fish oil, 20-30 parts of Schizochytrium powder, 7.5-12.4 parts of soy lecithin powder, 4-10 parts of maltitol, 8-12 parts of sodium butyrate, 8-15 parts of Chinese herbal medicine liquid, 0.2-0.8 parts of compound fermenting agent. Through steps such as raw material mixing, Chinese herbal medicine liquid fermentation, homogenization, puffing and spray drying in sequence, the feed quality control is carried out, so that the compound feed has a relatively high absorption rate and palatability, ensures the intake of the components of the Chinese herbal medicine fermentation liquid, significantly improves the survival rate and growth rate of freshwater fish, and has remarkable economic benefits.

The invention provides a process for efficiently recovering butyric acid from polyalcohol device concentrated wastewater, and relates to the technical field of industrial wastewater resource utilization, the process comprises the following steps: S1, wastewater pretreatment: filtering polyalcohol device concentrated wastewater containing sodium butyrate and sodium hydroxide to obtain pretreated wastewater; s2, acidification and neutralization: adding sulfuric acid into the pretreated wastewater to carry out acidification reaction, controlling the pH value at the end point of the reaction to be 1.5-2.5, neutralizing sodium hydroxide, and converting sodium butyrate into butyric acid; by accurately controlling acidification pH and reaction conditions, efficient and complete conversion from sodium butyrate to butyric acid is ensured, a two-stage counter-current extraction process is adopted, the mass transfer efficiency of butyric acid from a complex water phase to an organic phase is remarkably improved, the total extraction rate can reach 92% or above, the final butyric acid recovery rate is larger than or equal to 85%, the product purity is larger than or equal to 99.0%, and industrial-grade use requirements are met.

The invention discloses a special feed for breeding laying hens and a preparation method thereof, and belongs to the technical field of livestock and poultry feeds. The special feed for breeding the laying hens consists of a basal feed and a core functional compound. The core function compound innovatively comprises an organic trace element compound composed of ferric glycine, zinc methionine and selenium yeast, an antioxidant and absorption enhancer composed of astaxanthin and medium chain triglyceride (MCT), and an intestinal health and calcium and phosphorus metabolism regulator composed of sodium butyrate, beta-glucan and phytase. The key point of the preparation method is that MCT is adopted to pre-mix and coat the core functional compound components. Through synergism of all the components, the egg laying performance, egg quality, oxidation resistance and bone health of laying hens are effectively improved, and safe, efficient and environment-friendly laying hen breeding is achieved.

The present invention provides a ternary compound herbicide and its preparation method and application, relate to the field of agricultural science and technology, the ternary compound herbicide provided by the present invention, is composed of specific high-efficiency flupyralid, 2,4-drop butyrate sodium salt and fluazifop-butyl. Through the inventor's research, it is found that the three are combined, not only the weed killing spectrum is expanded, and its mechanism of action is different, and the synergistic effect of co-application is significant. Through experimental observation, the contact effect of fluazifop-butyl, for high-efficiency flupyralid, 2,4-drop butyrate sodium salt enters weeds and opens up a channel, improves the absorption and utilization rate of medicament, is the main reason for its synergistic effect. And the three have soil sealing effect, compared with the existing application agents such as glyphosate, not only have higher prevention effect to unearthed weeds, also have certain sealing effect to unearthed weeds.

The invention belongs to the technical field of animal husbandry breeding, and particularly relates to a breeding method for low-birth-weight Hu lambs. The invention relates to a breeding method of low birth weight Hu sheep lambs, which specifically comprises the following steps: lambs with birth weight lower than 1.5 standard deviation of a total average value eat breast milk in time after birth and live together with ewes; when the lambs are 5 days old, starter feed is added, sodium butyrate is fed into the lambs, and the lambs can freely eat the starter feed; the feeding mode of sodium butyrate is as follows: 40g of sodium butyrate is dissolved in 100ml of normal saline to prepare a solution with the final concentration of 0.4 g / ml, and each lamb is fed with 0.8 ml / kg-1 ml / kg of sodium butyrate; the body weight is measured once a week, and the feeding amount of sodium butyrate is adjusted according to body weight changes; the feed is stopped after 30-35 days of feeding with sodium butyrate, and weaning is carried out. By means of the method, healthy growth of the low-birth-weight Hu lambs can be achieved, the immune function and the oxidation resistance of animal bodies are improved, and therefore the production performance is improved.

The application discloses a porous aerogel-based intestinal sustained-release sodium butyrate preparation and a preparation process thereof, and belongs to the field of feed additives. The preparation process comprises the following steps: preparing a sodium butyrate solution and an alginate sodium and sodium lignosulfonate encapsulating solution containing allicin and / or gingerol by using water as a solvent; spraying and adsorbing the sodium butyrate solution on porous nanometer silicon dioxide aerogel to obtain a loaded semi-finished product; and then spraying and adsorbing the encapsulating solution on the surface of the loaded semi-finished product, drying and sieving to obtain the preparation. In the preparation, the content of the aerogel is 30%-60%, the content of the sodium butyrate is 40%-65%, the content of the alginate sodium and the sodium lignosulfonate is 5%-10%, and the content of the allicin and / or the gingerol is 0.4%-1.0%. The preparation has the characteristics of high gastric passage rate, excellent intestinal sustained-release performance, high-temperature granulation resistance and the like, effectively improves the bioavailability of the sodium butyrate, and can be widely applied to the feed additives for sows in the late gestation period and the lactation period.

This invention belongs to the technical field of laying hen feed additives, specifically relating to a selenium-enriched, high-DHA, low-cholesterol functional egg feed additive and its preparation method. The additive is prepared by compounding selenized ginseng polysaccharide, Schizochytrium algae powder, rosemary extract, natural vitamin E, EGCG green tea extract, phytosterol micron powder, sodium butyrate, β-glucan, phytase, modified attapulgite clay, and maltodextrin in specific weight parts, followed by low-temperature premixing activation, antioxidant encapsulation treatment, low-temperature compound granulation, sieving, and packaging processes. This invention, through the synergistic effect of its components, enables eggs to reach stable functional indicators within 14 days of feeding. The yolk selenium content reaches 32.1~38.2 μg / 100g, DHA content reaches 210.5~261.7 mg / 100g, and cholesterol reduction rate reaches 16.7%~22.3%. Simultaneously, eggshell strength increases by 12.1%~18.5%, egg production rate remains at 95.1%~96.8%, and egg breakage rate decreases by 59.0%~72.0%. The product exhibits good stability, requires low dosage, and is easy to use, making it perfectly suited for large-scale egg-laying hen farming scenarios and possessing outstanding economic and health value.

This invention belongs to the field of formulated feed technology for marine fish, specifically relating to a feed for improving the muscle quality of *Hexagrammos oysterfish* and its preparation method. The feed for improving the muscle quality of *Hexagrammos oysterfish* is made from the following raw materials in the indicated weight percentages: 93.5%–96.5% basic ingredients, 1% compound vitamins, 1% compound mineral salts, and 1.5%–4.5% formulated feed composition, with the sum of the weight percentages of all raw materials being 100%. The formulated feed composition consists of yeast β-glucan, chitosan oligosaccharide, and coated sodium butyrate, with the mass ratio of yeast β-glucan, chitosan oligosaccharide, and coated sodium butyrate being 1–3:1–3:1–2. This invention not only effectively reduces fat deposition in the body of *Hexagrammos oysterfish*, improving its muscle elasticity and chewiness, but also significantly improves the textural properties of the fish meat, thereby enhancing the overall muscle quality of *Hexagrammos oysterfish* and meeting consumer preferences.

The application discloses a method for comprehensive treatment of condensation wastewater and by-product sodium butyrate, which comprises the following steps: pumping the condensation wastewater into an oxidation tank, and introducing ozone into the oxidation tank to oxidize butyl aldehyde and butanol in the wastewater into butyric acid, and neutralizing the butyric acid with sodium hydroxide in the wastewater to generate sodium butyrate; pumping the material liquid after the oxidation into a buffer tank; sending the wastewater in the buffer tank to a two-effect evaporator to evaporate and concentrate, and cooling the concentrated sodium butyrate to 45-47 wt.% to flow into a concentrated liquid storage tank; sending the steam generated in the evaporation into a wastewater tank after heat exchange and cooling; cooling and crystallizing the concentrated liquid in the concentrated liquid storage tank; pumping the slurry after the crystallization into a filter-dryer integrated machine to filter and dry, so as to obtain sodium butyrate products, and sending the filtrate into the wastewater tank; and pumping the remaining wastewater into a sewage treatment plant for biochemical treatment and discharge after reaching the standard. The application fully recycles the useful components in the condensation wastewater, by-product sodium butyrate products with high added value are obtained, resource waste is avoided to the maximum extent, the product structure of an enterprise is enriched, and considerable economic benefits are brought to the enterprise.

This invention discloses a multilayer microsphere for the prevention and / or treatment of bacterial diarrhea, its preparation method, and its applications, relating to the field of biomedical technology. The multilayer microsphere has a three-layer core-shell structure: the core layer is loaded with *Lactobacillus plantarum* and sodium butyrate, the middle layer is a chitosan coating layer, and the outer layer is a sodium alginate coating layer. This invention has found that *Lactobacillus plantarum* and sodium butyrate have a significant synergistic antibacterial effect, effectively inhibiting the proliferation of pathogenic *Escherichia coli* and *Salmonella*. In vivo experiments have confirmed that the multilayer microsphere can effectively restore the body weight of diarrhea-prone animals, repair pathological damage to the jejunum and colon, and alleviate intestinal inflammation at the molecular level by inhibiting the activation of NF-κB and MAPK inflammatory pathways, downregulating the expression of pro-inflammatory factors IL-1β, IL-6, and TNF-α, and upregulating the level of the anti-inflammatory factor IL-10. The multilayer microsphere provided by this invention can serve as a novel, green, and safe formulation suitable for the prevention and control of bacterial diarrhea in livestock and poultry farming.

The invention provides a method for simultaneously recovering neopentyl glycol, sodium butyrate and n-butyl alcohol, according to the method, polyol wastewater containing natural sodium hydroxide is used as the only hydrolysis alkali source of neopentyl glycol heavy component waste liquid, and efficient hydrolysis of esters in the neopentyl glycol heavy component waste liquid can be realized without adding any additional alkali agent; neopentyl glycol, sodium butyrate and n-butyl alcohol in the hydrolysate are simultaneously recovered through ozone oxidation, distillation, rectification and the like, so that an integrated process of'alkali source internal circulation-multi-component synergistic conversion-gradient separation and purification 'is realized. In the invention, the recovery rate of neopentyl glycol is greater than or equal to 85%; meanwhile, the purity of neopentyl glycol is greater than or equal to 97%, the purity of sodium butyrate is greater than or equal to 95%, and the purity of n-butyl alcohol is greater than or equal to 98%, all reach the industrial-grade raw material standard, and can be directly sold or reused for production.

A nutraceutical composition, consisting of Nicotinamide Riboside in a range of 100-2000 mg or Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.

The invention relates to a preparation method of OSA starch-polysaccharide interpenetrating network microspheres for targeted delivery of butyric acid, which comprises the following steps: S1, carrying out esterification reaction on porous starch and octenyl succinic anhydride to obtain OSA starch; s2, dissolving sodium butyrate and zein in an alcoholic solution, and stirring for embedding to obtain zein-sodium butyrate; s3, OSA starch and zein-sodium butyrate are subjected to a reaction, and a compound is obtained; s4, dispersing the compound in a sodium alginate solution, dropwise adding into a calcium chloride solution for crosslinking to obtain OSA starch-polysaccharide gel microspheres, soaking the OSA starch-polysaccharide gel microspheres in a chitosan solution with a first concentration for primary coating, and soaking the OSA starch-polysaccharide gel microspheres in a chitosan solution with a second concentration for secondary coating; the first concentration is lower than the second concentration, and the difference between the first concentration and the second concentration is not lower than 1wt%. By constructing a core-carrier-interpenetrating network shell structure, the problems of low encapsulation efficiency, poor targeting property and weak stability in butyric acid delivery are solved.

The invention discloses a pork quality improving feed containing indole-3-propionic acid and a preparation method thereof, and belongs to the technical field of feeds. The feed capable of improving the pork quality is prepared from the following raw materials in parts by mass: 30 to 50 parts of soybean meal, 20 to 30 parts of corn flour, 10 to 20 parts of fish meal, 2 to 6 parts of whey protein powder, 0.08 to 0.15 part of indole-3-propionic acid, 0.5 to 1.2 parts of L-arginine, 0.3 to 0.7 part of L-glutamine, 0.3 to 0.7 part of sodium butyrate, 0.05 to 0.2 part of beta-hydroxy-beta-methylbutyric acid and 0.1 to 0.5 part of astragalus polysaccharide. The feed is high in conversion rate and can improve the pork quality.

The invention belongs to the technical field of medicines, and particularly provides a novel application of sodium butyrate in preparation of a product for treating DYT25 dysmnesia. DYT25 muscular dystonia mouse (Gal + / -) experiment evaluation proves that the sodium butyrate can obviously increase the falling time, the learning rate and the initial coordination in an accelerated bar rotating experiment; the descending time and the turning time in a vertical rod experiment are remarkably shortened, and the passing time and the sliding frequency in a horizontal rod experiment are shortened; and the movement distance and the average speed in an open field experiment are increased. Therefore, the sodium butyrate provided by the invention can be applied to preparation of products for treating DYT25 dysmnesia.

The invention discloses a pig heat stress resistant composite device based on environmental enrichment and a preparation method thereof, and belongs to the technical field of livestock breeding. The device is composed of a multifunctional base body and a built-in degradable chewing-resistant core body. The matrix contains active ingredients aiming at heat stress, and comprises organic electrolyte, sodium butyrate serving as an intestinal mucosa protective agent, theanine serving as a nerve sedative and antioxidant vitamins; and the core body is an environmental enrichment made of natural fibers. The core body induces the pigs to prolong licking and biting time, sufficient intake of active ingredients is ensured when the feed intake is reduced, meanwhile, the exploration and playing nature of the pigs is met, the carving behaviors are reduced, and dual relief of physiological and psychological stress is achieved. The preparation method comprises the steps of core body pretreatment, mixing, pre-pressing implantation, pressing and low-temperature curing. The invention solves the problem of insufficient intake of intervention components under heat stress, and has obvious anti-stress effect.

The invention relates to the technical field of pesticides, in particular to a pesticide composition for weeding and application thereof. The invention provides a pesticide composition. The pesticide composition comprises a component a, a component b and a component c, wherein the component a is quinclorac; the component b is 2, 4-D sodium butyrate; and the component c is atrazine or terbuthylazine. The compound herbicide provided by the invention combines quinclorac, 2, 4-D sodium butyrate and atrazine (or terbuthylazine), and the inventor finds that herbicides with different action mechanisms and herbicide controlling spectrums have a synergistic effect after combined action through a large number of experiments, the herbicide controlling spectrum is expanded, and weeds in sorghum fields can be effectively prevented and controlled. And a new medicament variety and a new selection approach are added for weed prevention and control in the sorghum field.

The invention discloses a compound composition for gastrointestinal care of dogs and cats and a preparation method of the compound composition. The compound composition comprises the following components in parts by weight: a medicine and food homologous formula consisting of codonopsis pilosula, bighead atractylodes rhizome, poria cocos, Chinese yam, gordon euryale seed, lotus seed, coix seed, purslane, pumpkin powder and hawthorn; the functional additive consists of coated sodium butyrate, medium-chain fatty acid, mannan oligosaccharide, fructooligosaccharide and L-glutamine; the coating material is chitosan and sodium alginate, and the weight ratio of the chitosan to the sodium alginate is 1: (0.21-0.27). The preparation method comprises the following steps: carrying out superfine grinding on the medicinal and edible composition to 10-50 microns, uniformly mixing the functional additive, carrying out nanoscale coating treatment by adopting chitosan-sodium alginate to form a coating layer of 50-200 nanometers, and finally drying and sieving to obtain a finished product. Through scientific compounding of a medicinal and edible composition and functional additives and combination of a nano coating technology, directional release of intestinal tracts is realized, immune functions of dogs and cats are remarkably improved, intestinal barriers are improved, flora balance is adjusted, and the feed additive is safe, effective and suitable for long-term use.

A nutraceutical composition, consisting of at least of Berberine in a range of 500-1500 mg, Trimethylglycine (TMG) in a range of 500-2000 mg, Microdose Lithium in range of 1-5 mg, Epigallocatechin-3-gallate (EGCG) in a range of 100-500 mg, Fisetin in a range of 100-1000 mg, Resveritrol in a range of 150-1000 mg, Glutathione in a range of 250-1000 mg, Nicotinamide Mononucleotide (NMN) in a range of 250-1000 mg or Nicotinamide Riboside (NR) in a range of 100-2000 mg, Calcium Alphaketoglutarate (CaAKG) in a range of 300-2000 mg, Spermidine in a range of 0.5-10 mg, Urolithin A in a range of 250-2000 mg, Hyaluronic acid in a range of 100-240 mg, Fucoidan in a range of 100-4000 mg, and Sodium Butyrate in a range of 100-3000 mg.

The invention provides a special acidifier for liquid feeding as well as a preparation method and application thereof, and belongs to the technical field of animal feed additives. The special liquid acidifier for feeding comprises the following components in parts by mass: 25-30 parts of butyric acid, 20-25 parts of lactic acid, 10-15 parts of acetic acid, 10-15 parts of potassium diformate, 5-10 parts of malic acid, 5-10 parts of sodium butyrate and 10-15 parts of sodium citrate. The special acidifier for liquid feeding can be directly used as a cleaning reagent of a liquid feeding system or an additive in a liquid feed fermentation process. When the cleaning agent is used as the cleaning agent, liquid after cleaning can be directly used for next fermentation, waste of water resources can be remarkably reduced, feed deterioration is avoided, and forward fermentation is promoted. When being used as an additive, the feed additive can improve the nutritional value of liquid-state fermented feed and improve the growth performance and serum oxidation resistance of animals.

The invention provides a functional fish feed additive as well as a preparation method and application thereof, and relates to the technical field of healthy aquaculture. Specifically, the additive disclosed by the invention comprises 10-50 parts of sodium butyrate-oligosaccharide eutectic, 10-30 parts of a yeast postbiotic product, 20-60 parts of a fermented traditional Chinese medicine compound and 10-30 parts of Sanhuang powder, the yeast postbiotic product is prepared by fermenting raw materials including kluyveromyces marxianus, corn and palm meal at constant temperature, and the fermented traditional Chinese medicine compound is prepared by anaerobic fermentation of raw materials including herba andrographitis, red-knees herb, selenium-enriched tea powder and folium artemisiae argyi powder. The additive disclosed by the invention can effectively prevent and treat infection of streptococcus to fishes through three dimensions, effectively overcomes the defect of high drug resistance or high-dosage pollution risk of conventional antibiotics or chemical preparations, and has a good application prospect.

The present invention relates to the technical field of weaned piglet feeds, and particularly discloses a weaned piglet growth performance and intestinal health improving feed, which comprises the following raw materials by weight: 50-65 parts of corn, 15-25 parts of soybean meal, 2-5 parts of fish meal, 3-8 parts of whey powder, 1-3 parts of soybean oil, 0.5-1.5 parts of stone powder, 0.5-1.5 parts of calcium hydrophosphate, 0.2-0.5 part of edible salt, and 0.1-0.4 part of lysine. The feed is prepared from the following raw materials in parts by weight: 0.05 to 0.15 part of methionine, 0.05 to 0.15 part of threonine, 0.5 to 1.5 parts of premix, 0.05 to 0.10 part of sodium butyrate, 0.01 to 0.03 part of bacillus subtilis and 0.005 to 0.015 part of origanum oil. The feed for improving the growth performance and intestinal health of the weaned piglets can improve the antioxidant capacity in serum of the weaned piglets, promote the development of intestinal villus, maintain the integrity of intestinal barriers, improve the immune function of the intestinal tracts and increase the amino acid transport of the intestinal tracts.

The present invention relates to the field of crop cultivation, and particularly to the application of sodium butyrate, a rhizosphere soil hydrogen sulfide promoter, and a method for improving plant drought resistance. The present invention provides the application of sodium butyrate as a rhizosphere soil hydrogen sulfide promoter. The sodium butyrate of the present invention can be used as a rhizosphere soil hydrogen sulfide promoter to achieve the effect of increasing the abundance of sulfate-reducing bacteria (SRB) in the soil and promoting the soil to generate more hydrogen sulfide, and ultimately achieve the purpose of improving plant stress resistance, especially drought resistance.

The invention relates to the technical field of animal feeds, and particularly provides a feed for promoting intestinal repair of aquatic animals and a preparation method of the feed. Comprising the following raw materials in percentage by mass: 47% of duck blood, 0.5%-1% of vitamin C, 0.1%-0.3% of tea polyphenol, 0.5%-1.5% of saccharomyces cerevisiae, 0.5%-1.5% of lactobacillus plantarum, 4%-6% of beta-glucan, 2%-4% of stachyose, 0.1% of sodium butyrate and 30% of vitamin C, 35% of plant extract and the balance of pure water. According to the feed for promoting intestinal repair of the aquatic animals and the preparation method of the feed, food calling, intestinal motility recovery and intestinal beneficial bacterium density increase are taken into consideration.

The application discloses application of sodium butyrate in preparation of a medicine for treating intracranial hemorrhage, in particular, application of sodium butyate in preparation of a medicine for treating neonatal intraventricular hemorrhage, researches show that the sodium butyate is used for preventive neuroprotection of IVH of high-risk premature infants (fetal age is less than 32 weeks), secondary brain injury is reduced, and long-term neurodevelopmental outcome is improved; the sodium butyate is used for treating neonatal intraventricular hemorrhage, brain ventricle expansion is reduced, neuron survival is increased, and nerve function is improved; and the sodium butyate can also improve motor function and cognitive function, and has the effect of comprehensive neuroprotection. The application provides a new medicine source for treating intracranial hemorrhage, in particular, neonatal intraventricular hemorrhage.

The invention discloses a compound feed additive for relieving high-fat-induced liver injury of micropterus salmoides as well as a preparation method and application of the compound feed additive, the additive is prepared from guar gum, sodium butyrate and naringenin, and the mass percent of the guar gum, the sodium butyrate and the naringenin in a feed is 0.05-0.2%, and the mass percent of the sodium butyrate and the mass percent of the naringenin are 0.05-2%. It is found for the first time that the guar gum-sodium butyrate-naringenin combination with a specific ratio can cooperatively relieve fish liver injury through multiple channels, reduce liver lipid deposition of micropterus salmoides, enhance liver oxidation resistance, apoptosis resistance and inflammation resistance, and comprehensively improve the fish liver health level.

The present invention discloses a preparation method and application of a liquid compound microecological preparation and its protective agent. The components of the protective agent include glucose, soybean meal, peptone, sodium sulfite, disodium hydrogen phosphate, citric acid, calcium carbonate, glycerol, sodium butyrate, sodium lactate, D-sodium propionate, and nucleoside phosphorylase. By adding a certain proportion of the protective agent to the liquid compound microecological preparation, the present invention can enable the bacteria in the liquid compound microecological preparation to have a longer preservation time, with a slow decline in the bacterial count during long-term preservation, ensuring a higher viable bacteria count and stronger bacterial vitality, and greatly promoting production activities.