4 results about "Sodium butanoate" patented technology

The present application belongs to the technical field of animal feed, and provides a fermented feed for reducing the diarrhea rate of piglets and a preparation method thereof. The present application adopts a design of pre-embedding A1-derived microgel particles and B1-derived core-shell microcapsules and then spraying and synergistic matching: the microgel particles are combined by cross-linking network of sodium alginate and anhydrous calcium chloride ions and gelatin, and the fermented base powder is embedded in the gel matrix; the core-shell microcapsules are prepared by using sodium butyrate and / or calcium formate as core material and sodium alginate-anhydrous calcium chloride ion cross-linking layer as shell material, and then applied to the base particles by fluidized bed post-spraying, so as to realize the structure protection and intestinal directional slow release of active components in the hot-wet-shearing granulation process. The present application solves the technical contradiction that the high-strength granulation and the structural integrity of the microcapsule are difficult to be considered together, and the storage stability and the swelling regulation of the microgel are difficult to be matched, the diarrhea rate of piglets is significantly reduced, the storage stability is good, and the present application has wide application value in piglet breeding.

This invention belongs to the technical field of laying hen feed additives, specifically relating to a selenium-enriched, high-DHA, low-cholesterol functional egg feed additive and its preparation method. The additive is prepared by compounding selenized ginseng polysaccharide, Schizochytrium algae powder, rosemary extract, natural vitamin E, EGCG green tea extract, phytosterol micron powder, sodium butyrate, β-glucan, phytase, modified attapulgite clay, and maltodextrin in specific weight parts, followed by low-temperature premixing activation, antioxidant encapsulation treatment, low-temperature compound granulation, sieving, and packaging processes. This invention, through the synergistic effect of its components, enables eggs to reach stable functional indicators within 14 days of feeding. The yolk selenium content reaches 32.1~38.2 μg / 100g, DHA content reaches 210.5~261.7 mg / 100g, and cholesterol reduction rate reaches 16.7%~22.3%. Simultaneously, eggshell strength increases by 12.1%~18.5%, egg production rate remains at 95.1%~96.8%, and egg breakage rate decreases by 59.0%~72.0%. The product exhibits good stability, requires low dosage, and is easy to use, making it perfectly suited for large-scale egg-laying hen farming scenarios and possessing outstanding economic and health value.

This invention belongs to the field of formulated feed technology for marine fish, specifically relating to a feed for improving the muscle quality of *Hexagrammos oysterfish* and its preparation method. The feed for improving the muscle quality of *Hexagrammos oysterfish* is made from the following raw materials in the indicated weight percentages: 93.5%–96.5% basic ingredients, 1% compound vitamins, 1% compound mineral salts, and 1.5%–4.5% formulated feed composition, with the sum of the weight percentages of all raw materials being 100%. The formulated feed composition consists of yeast β-glucan, chitosan oligosaccharide, and coated sodium butyrate, with the mass ratio of yeast β-glucan, chitosan oligosaccharide, and coated sodium butyrate being 1–3:1–3:1–2. This invention not only effectively reduces fat deposition in the body of *Hexagrammos oysterfish*, improving its muscle elasticity and chewiness, but also significantly improves the textural properties of the fish meat, thereby enhancing the overall muscle quality of *Hexagrammos oysterfish* and meeting consumer preferences.

This invention discloses a multilayer microsphere for the prevention and / or treatment of bacterial diarrhea, its preparation method, and its applications, relating to the field of biomedical technology. The multilayer microsphere has a three-layer core-shell structure: the core layer is loaded with *Lactobacillus plantarum* and sodium butyrate, the middle layer is a chitosan coating layer, and the outer layer is a sodium alginate coating layer. This invention has found that *Lactobacillus plantarum* and sodium butyrate have a significant synergistic antibacterial effect, effectively inhibiting the proliferation of pathogenic *Escherichia coli* and *Salmonella*. In vivo experiments have confirmed that the multilayer microsphere can effectively restore the body weight of diarrhea-prone animals, repair pathological damage to the jejunum and colon, and alleviate intestinal inflammation at the molecular level by inhibiting the activation of NF-κB and MAPK inflammatory pathways, downregulating the expression of pro-inflammatory factors IL-1β, IL-6, and TNF-α, and upregulating the level of the anti-inflammatory factor IL-10. The multilayer microsphere provided by this invention can serve as a novel, green, and safe formulation suitable for the prevention and control of bacterial diarrhea in livestock and poultry farming.