The invention relates to a honeycomb manganese denitration catalyst and a preparation method thereof. The method includes the following steps that manganese salt and a complexing agent are dissolved in water, titanium dioxide is added and stirred, ultrasonic dipping, drying and grinding are conducted, and Mn-Ti oxide solid particles are obtained, wherein the molar ratio of the manganese salt to the complexing agent is (65-187):1; metal salt and cerium salt are dissolved in water to obtain a mixed metal solution, wherein metal salt is at least one of ferric salt, cobalt salt, lanthanum salt, antimony salt and nickel salt; a pore-forming agent, an adhesive, an extrusion aid, a reinforcing agent, the Mn-Ti oxide solid particles and the mixed metal solution are mixed and formed into a honeycomb blank, and drying and forging are conducted. The catalyst is good in active component dispersity, is not easily sintered, good in pore structure, large in porosity and high in mechanical strength, the axial compressive strength of the catalyst is 4.7-5.1 MPa, and the radial compressive strength of the catalyst is 1.2-1.4 MPa. The porosity of the catalyst is 84-90%. The catalyst prepared through the method has relatively high denitration activity in the range of 120-250 DEG C and is suitable for low-temperature denitration.