The invention provides a preparation method of a
cartilage regeneration
scaffold material. The preparation method is characterized in that fresh
skin at back, face or buttock of a dead animal is taken as a
raw material and is subjected to treatment processes such as deep and low-
temperature treatment, depilation, inactivation of
virus,
decellularization, structure remodeling, crosslinkage, freeze-
drying, re-modification and sterilization, thus obtaining a finished product. The
cartilage regeneration
scaffold material prepared by the method disclosed by the invention can be used for promoting adhesion and growth of
cartilage cells and promoting healing of
articular cartilage injuries. The product belongs to a natural
extracellular matrix ingredient which is beneficial to adsorption, proliferation and differentiation of the cells, also has a certain
mechanical strength, can exist in the body for a long time in the form of a tissue filler, also has good tissue affinity and compatibility, and can be used for inducing
cartilage cells to grow therein so as to rebuild the cartilage, promote the adhesion and growth of the
cartilage cells, promote the healing of the
articular cartilage injuries and restore articular defects, so the cartilage regeneration
scaffold material is a novel regeneration
scaffold material for effectively restoring
articular cartilage defects.