32 results about "Furazolidonum" patented technology

A detection method simultaneously detects residue of multiple synthetic antibacterial agents in aquatic products by a high performance liquid chromatography. The synthetic antibacterial agents mainly comprise sulfadiazine SD, sulfamerazine SMR, sulfadimidine SDD, sulfadimethoxine SDM, furazolidone FZD, oxolinic acid OXA, nalidixic acid NAA and the like. The multiple synthetic antibacterial agents in an aquatic product sample are extracted by acetonitrile, degreased by normal hexane, concentrated, purified by a solid phase extraction column (alumina neutral) or a C18 solid phase extraction column, analyzed by a liquid chromatograph, detected by an ultraviolet detector, and quantified by an external standard method. The method can quickly, sensitively and accurately detect multiple target compounds to greatly reduce detection cost and shorten detection time.

The invention relates to a colloidal gold immunochromatography test strip for detecting furazolidone metabolites and a preparation method and application of the colloidal gold immunochromatography test strip, and belongs to the technical fields of immunology and veterinary drug residue analysis. The test strip comprises a base plate, a sample pad, a colloidal gold pad, a coating membrane and a water absorption pad; protective membranes are arranged at the two ends of the test strip, and the sample pad, the colloidal gold pad, the coating membrane and the water absorption pad are sequentially stuck to the base plate; the colloidal gold pad is coated with colloidal gold-labeled monoclonal antibodies which can recognize the furazolidone metabolites; the coating membrane is provided with an invisible detection line printed by a carrier protein solution coupled with the furazolidone metabolites and an invisible quality control line printed by a goat anti-mouse IgG solution. The colloidal gold immunochromatography test strip has the advantages of being convenient and rapid to operate, visual, high in timeliness and the like and is wide in application range, low in cost and convenient to apply and popularize.

The invention provides a medicine for treating epistaxis through oral administration and external use and a method thereof. The following components are combined for use as the medicine in parts by weight: 0.5 part of chloramphenicol tablets, 0.5 part of cefradine injection powder, 0.5 part of furazolidone tablets, 30 parts of radix rehmanniae, 30 parts of prepared rhizome of rehmannia, 25 parts of garden burnet root, 30 parts of golden cypress, 30 parts of fructus forsythiae, 25 parts of caulis spatholobi and 25 parts of liquorice, wherein western medicines, namely the chloramphenicol tablets, the cefradine and the furazolidone tablets, are bactericidal medicines for external use, and wherein traditional Chinese medicines, namely radix rehmanniae, prepared rhizome of rehmannia, garden burnet root, golden cypress, 30 parts of fructus forsythiae, caulis spatholobi and liquorice are decocted with water and used as medicines for oral administration. The medicine provided by the invention is obvious in medicine treatment effect, quick to stop bleeding and worthy of popularization and utilization.

The invention discloses a hapten, as well as a preparation method and application thereof, and specifically relates to a furazolidone metabolite hapten. The invention also discloses a preparation method of the hapten and application thereof. A kit quick detection product established based on the furazolidone metabolite hapten is convenient to use, low in detection cost, and efficient, accurate and quick in detection method; the kit quick detection product is capable of detecting a large batch of samples at the same time, and thus suitable for on-site supervision of furazolidone metabolite residues in animal derived food and screening of lots of samples.

The invention discloses a manufacturing method of a biological immunity sensor which is constructed on the basis of a functional nanometer material and has electrogenerated chemiluminescence and photoeletrochemistry double signal developing strategies.The manufactured sensor is easy to operate, convenient to carry, high in detection speed, low in cost and capable of being used for detecting furazolidone in the fields of daily production and life fast and sensitively.

The invention relates to the field of medicine, and in particular relates to a medicine for treating stomach disease and an application. The medicine for treating stomach disease comprises the following components in parts by mass: 310-620 parts of furazolidone, 202-520 parts of chloramphenicol, 105-210 parts of propantheline bromide, 2,000-3,000 parts of licorice powder and 2.01-3.95 parts of vitamin B6. The medicine is used for treating acute gastritis, chronic superficial gastritis, chronic atrophic gastritis, gastric ulcer, bile reflux gastritis or duodenal ulcer. According to the medicine for treating stomach disease and application provided by the embodiment of the invention, multiple components are combined to realize sterilization and suppression effects so as to protect and maintain the stomach; and the raw materials are rich, the price is low, and the treatment cost is lower. In a process of treating stomach disease, the medicine has the advantages of high cure rate, short cure time, perfect effect, simplicity and convenience in preparation, simple preparation flow of technological medicines and obvious curative effect, is safe to take, and avoids adverse reaction.

The invention relates to internally and externally applied medicines for treating haemorrhoids and a method. The internally and externally applied medicines for treating haemorrhoids disclosed by the invention are formed by combining the following medicines in weight ratio: 0.5 part of furazolidone tablets, 0.5 part of norfloxacin capsules, 25 parts of the root bark of white mulberry, 20 parts of radix rehmanniae, 20 parts of honeysuckle, 17 parts of Chinese rhubarb, 25 parts of felwort and 15 parts of the root of bidentate achyranthes. According to the invention, the mixture of furazolidone and starch paste is injected to the haemorrhoids wound in the anorectum of a person through a sterilization syringe without a needle, so that sterilization is carried out at high concentration; in addition, matched with the internally applied traditional Chinese medicines for cooling and detoxifying, haemorrhoids can be treated.

The invention discloses a feed additive with the effects of preventing and treating vibriosis of rainbow trout and application thereof. The additive is prepared from the following components in partsby weight: 15-20 parts of Chinese rhubarb, 12-16 parts of baikal skullcap root, 18-23 parts of medicine terminalia fruit, 3-5 parts of galangal, 13-18 parts of radix sanguisorbae, 5-7 parts of licorice, 15-20 parts of bunge corydalis herb, 5-9 parts of pomegranate rind, 0.003-0.005 part of sulfanilamide, 0.002-0.004 part of furazolidone and 0.05-0.07 part of chloramphenicol. The feed additive withthe effects of preventing and treating vibriosis of rainbow trout has the beneficial effects: the additive disclosed by the invention has reasonable compatibility among the components, combines Chinese and western medicines, has an obvious synergistic effect as well as obvious antibacterial, anti-inflammation and immunity-enhancing effects, has obvious antibacterial and bactericidal actions on the pathogenic bacteria of vibriosis, has high effect taking speed and exact curative effects, achieves the purposes of preventing and treating the vibriosis of the rainbow trout, and is not likely to generate drug tolerance and free of any toxic side effects.

The invention discloses a high performance liquid chromatography detection method of an indometacin furazolidone suppository. A mobile phase of the high performance liquid chromatography detection method is formed by mixing acetonitrile and a 0.08-0.12 mol/L glacial acetic acid solution according to the volume ratio of (45-55): (55-45), and a stationary phase is a C18 silica gel chromatographic column. According to the method disclosed by the invention, the contents of two components, namely indometacin and furazolidone, are simultaneously separated and determined by adopting an HPLC method, the sample pretreatment and analysis method is simplified, the analysis efficiency of indometacin furazolidone suppository content determination is improved, and the method has the advantages of high analysis speed, high separation efficiency, high detection sensitivity, automation, wide application range and simple treatment.

The invention discloses a preparation method of 3-amino-2-oxazolidinone (AOZ). The method comprises the following steps: 1) carrying out a reaction on ethylene glycol and PBr3 to obtain 2-bromoethanol; 2) carrying out a substitution reaction on 2-bromoethanol and an alkali, then adding hydrazine hydrate into the system, continuously carrying out a ring-opening reaction, and removing excessive 2-bromoethanol and water after the reaction is completed to obtain an intermediate 2-hydrazinoethanol; and 3) in the presence of an alkali, carrying out a reaction on 2-hydrazinoethanol and diethyl carbonate to obtain 3-amino-2-oxazolidinone (AOZ). According to the method, a nitrofuran metabolite AOZ is synthesized by adopting a one-pot method at the rear half part, so that the loss of a separated andpurified sample in the synthesis process is greatly reduced.

The invention relates to the field of medicines, and in particular relates to a quick-acting anti-influenza cold capsule. The quick-acting anti-influenza cold capsule is characterized by being prepared from the following raw materials in parts by weight: 50-150 parts of acetaminophen, 50-150 parts of pseudoephedrine hydrochloride, 30-50 parts of chlorpheniramine maleate, 1-3 parts of dioxopromethazine, 10-30 parts of vitamin C, 10-30 parts of vitamin B1, 10-30 parts of vitamin B2, 10-30 parts of vitamin B6, 1-3 parts of furazolidone, 50-150 parts of radix isatidis and 30-50 parts of radix bupleuri. The quick-acting anti-influenza cold capsule provided by the invention is combination of traditional Chinese medicines and western medicines, and is capable of regulating a nervous system of the human body through western medicine components to reach the effects of relieving pain, clearing heat, relieving cough, preventing asthma, and relieving the symptoms such as rhinobyon and pharyngeal swelling and pain; necessary vitamins for human metabolism and the traditional Chinese medicines such as radix isatidis are added, so that the quick-acting anti-influenza cold capsule is capable of enhancing the resistivity of a human body and treating both symptoms and root causes from improvement of the immunity, and is short in treatment course, fast in acting, and free of causing doze after being taken.