58 results about "Thiol functionalized" patented technology

The present invention relates to a method of preparing a carbon nanotube-quantum dot conjugate having a high density of quantum dots (QDs) on its surface. This method involves providing a plurality of semiconductor quantum dots and providing a thiol-functionalized carbon nanotube having a plurality of terminal thiol groups on its surface. The plurality of semiconductor quantum dots are attached to the surface of the carbon nanotube under conditions effective to yield a carbon nanotube-quantum dot conjugate having a high density of quantum dots on its surface. The present invention also relates to a carbon nanotube-quantum dot conjugate having a high density of quantum dots on its surface. The present invention further relates to a photodetector device. This device includes a substrate and a nanocomposite layer. The nanocomposite layer includes a plurality of the carbon nanotube-quantum dot conjugates previously described.

Provided according to some embodiments of the invention are methods of forming co-condensed silica particles. In some embodiments, the methods include reacting a thiol-containing silane and a backbone alkoxysilane in a reaction solution that comprises water to form thiol-functionalized co-condensed silica particles, wherein the thiol-functionalized co-condensed silica particles include a polysiloxane matrix and at least some of thiol groups are present within the polysiloxane matrix; and reacting the thiol-functionalized co-condensed silica particles with a nitrosating agent to provide the S-nitrosothiol-functionalized co-condensed silica particles. In some embodiments, provided are S-nitrosothiol-functionalized co-condensed silica particles.

The invention relates to a thiol functionalization method and application of a nano hole metal-organic framework material. Through the coordination of the nano hole metal-organic framework material containing a coordination unsaturated active site and a dithiol compound, a certain proportion of thiol in a dithiol compound molecule is connected with the coordination unsaturated active site of the nano hole metal-organic framework material through a coordination bond, and a thiol functional group is grafted to a metal-organic framework, so that the thiol-functionalized nano hole metal-organic framework material is generated. The thiol-functionalized nano hole metal-organic framework material can be used as an adsorption and separation material of heavy metal ions, and is applied to removal of heavy metal ions in a water body.

The invention pertains to a coating composition comprising a) a first compound comprising at least one bicyclo-orthoester group, p0 b) a second compound comprising at least two isocyanate groups, and c) a third compound comprising at least one thiol group. The invention also relates to a process for curing the present coating composition. More particularly, the latent hydroxyl groups of the bicyclo-orthoester groups have to be deblocked and reacted with the isocyanate-groups of the second compound if the present coating composition is to be cured.

The invention provides a preparation method of a polyvinylidene fluoride oil-water emulsion separation membrane with characteristics of good surface hydrophilicity and underwater super oleophobicity.According to the method, hyperbranched polydimethylaminoethyl methacrylate with controlled molecular weight is prepared by using dimethylaminoethyl methacrylate containing a tertiary amine group as amonomer through a reversible addition-fragmentation chain transfer polymerization method; the hyperbranched polydimethylaminoethyl methacrylate with controlled molecular weight and 1,3-propane sultoneare subjected to a quaternization reaction to prepare a hyperbranched zwitterionic polymer; a thiol-functionalized hyperbranched zwitterionic polymer is obtained through an aminolysis reaction; and the hyperbranched zwitterionic polymer is introduced onto the surface of a polyvinylidene fluoride membrane by using a surface biomimetic chemical modification method so as to effectively improve the hydrophilicity of the polyvinylidene fluoride membrane, such that the separation membrane has efficient and stable oil-water emulsion separation ability. According to the present invention, the polyvinylidene fluoride membrane is subjected to surface modification, the used modifier has the controlled structure, and the prepared oil-water emulsion separation membrane has excellent anti-pollution performance, and has important practical application value in oil-water separation.

The invention discloses gold nanoparticles and a preparation method thereof. The method comprises the steps of enabling chloroauric acid hydrated to make contact with a reducing agent on the condition that a solvent and a stabilizer exist, wherein the stabilizer is thiol-functionalized methoxypolyethylene glycol amine. The preparation method of the gold nanoparticles is easy to achieve, the sizes of the obtained gold nanoparticles are small and uniform, the gold nanoparticles are good in dispersity in the solution and wide in application prospect, and a new simple and direct way is provided for preparation of the gold nanoparticles.

The invention discloses folic acid-functionalized drug-loaded mesoporous silica and a preparation method thereof. The folic acid-functionalized drug-loaded mesoporous silica of the present invention is prepared according to the following steps: 1) adopting orthosilicate as a silicon source, adopting an n-hexadecyl quaternary ammonium salt as a template agent, adopting mercaptopropyl trimethoxysilane as a functionalization reagent, and adopting a method of copolycondensation, synthesis and grafting to prepare thiol-functionalized mesoporous silica; 2) carrying out a reaction of the thiol-functionalized mesoporous silica and 2-(pyridindithio)ethyl ammonium chloride to obtain amino-functionalized mesoporous silica adopting a disulfide bond as a linker; 3) adopting a physical adsorption method to assemble a drug into pore channels of the mesoporous silica; and 4) linking folic acid to the mesoporous silica through the disulfide bond with a covalence effect to obtain the folic acid-functionalized drug-loaded mesoporous silica. The product of the present invention has characteristics of folic acid targeting effect, large specific surface area, high thermal stability, no toxicity, high drug loading rate, and effective prevention from drug leakage.

The invention discloses preparation of a thiol-ended polyvinyl alcohol quantum dot composite material. The preparation of the thiol-ended polyvinyl alcohol quantum dot composite material comprises the following steps: with acetic anhydride as an acetylation reagent and concentrated sulfuric acid as an esterification catalyst, under an acidic condition, carrying out an esterification reaction on polyvinyl alcohol and mercaptoacetic acid so as to obtain thiol-functionalized polyvinyl alcohol; complexing thiol-functionalized polyvinyl alcohol serving as a stabilizer with cadmium ion and sulfur ion, so as to obtain the thiol-ended polyvinyl alcohol quantum dot composite material with excellent stability, dispersity and optical property. Experiments show that with the addition of Cu<2+> with different concentrations (1-1000nM) in an aqueous solution of the thiol-ended polyvinyl alcohol quantum dot composite material, fluorescence of the solution shows certain linear extinction; therefore, the thiol-ended polyvinyl alcohol quantum dot composite material has the characteristics of high detection speed and ultra sensitiveness when used for detecting trace Cu<2+> in a water sample.

The present invention relates to a dual function catalyst and a preparation method thereof, wherein a sulfonic acid function group is grafted on the surface of the catalyst, and is adopted as an acid to provide acidity for cellulose hydrolysis so as to produce glucose, and the glucose obtained through hydrolysis is subjected to further hydrogenation under a hydrogen gas condition with the supported metal nanoparticles so as to produce sorbitol, such that one step conversion of cellulose into sorbitol under mild reaction conditions is achieved. The catalyst preparation method comprises: 1) preparing a thiol functionalized silica gel: grafting a thiol function group on the surface of a silica gel; 2) preparing a sulfonic acid functionalized silica gel: oxidizing the thiol grafted on the surface into sulfonic acid; and 3) adopting an equal volume impregnation method to prepare the metal nanoparticle-supported sulfonic acid functionalized silica catalyst, wherein the obtained catalyst can be used for conversion of cellulose to prepare sorbitol. The catalyst has characteristics of simple preparation method, low raw material cost, high activity and good stability, and is suitable for cellulose conversion reactions.

There is provided a nanocomplex having a core-shell structure. The shell of the nanocomplex comprises a functionalized hyaluronic acid while the core of the nanocomplex comprises a flavonoid encapsulating a metal-containing compound. Preferably, the flavonoid is epigallocatechin gallate (EGCG) and the hyaluronic acid is thiol-functionalized and subsequently conjugated to the flavonoid. There is also provided a method of forming the nanocomplex, a pharmaceutical composition comprising the nanocomplex, medical uses of the nanocomplex and a method of treating a patient, preferably with cancer using the nanocomplex.

The invention discloses a coating system applied to the surface of a plastic substrate. The coating system comprises a UV curing primer and a wear-resistant protective PVD coating, wherein the UV curing primer comprises: 30-60 parts of organosilicone-modified urethane acrylate, 20-40 parts of epoxy acrylate, 5-20 parts of a reactive diluent, 5-20 parts of a thiol functional compound, 2-5 parts ofa photoinitiator, and 0.5-2 parts of an addition agent; the wear-resistant protective PVD coating is a TiaX(1-a)CrNsOt coating, wherein X represents Si or/and Al; a is greater than or equal to 0.5 andsmaller than 1; the sum of r, s and t is 1; and the thickness of the coating is between 0.5 microns to 5 microns. The surface of a plastic product prepared by the coating system has metallic luster,and the coating is good in adhesive force, excellent in durability, excellent in wear resistance and scratch resistance, and suitable for packaging products, craft decorations, electronics, home appliances and automobile industries and the like.

The invention relates to a novel polyphosphorus-based chain-end thiol-functionalized polymer, the polymer chain of which comprises units bearing at least one pendant phosphonate function and/or at least one pendant phosphonic function along the chain. This novel polymer is quite particularly suited to participating in a thiol-ene coupling reaction, which affords the possibility of grafting the polyphosphorus-based polymers onto diene polymers, for example.

The invention discloses a preparation method of a high-sensitivity functionalized silver nanoparticle-doped aniracetam MIECS (Molecular Imprinting Electrochemical Sensor). The preparation method is characterized by taking aniracetam as a template molecule, dihydromyrcenol as a functional monomer, hydrocortisone acetate as a coupling agent and decyl mercaptan functionalized silver nanoparticles as a doping agent, thus preparing the high-sensitivity decyl mercaptan functionalized silver nanoparticle-doped aniracetam MIECS. An analysis method is simple and practical, and the disadvantages of complexity, expensive price of equipment and low sensitivity of a previous analysis method are overcome.

The invention discloses a PVDF (Polyvinylidene Fluoride)-SiO2 composite membrane for synthesizing thiol-functionalized mesoporous silica microspheres in membrane pores and a preparation method thereof, and belongs to the field of preparation of membrane materials. The preparation method comprises the following steps: (1) modifying a PVDF polymer with MAA (Methacrylic Acid); (2) preparing the modified polymer obtained in the step (1) into a casting solution; (3) preparing the casting solution obtained in the step (2) into a membrane through a solution phase inversion method; (4) synthesizing thiol-functionalized mesoporous silica microspheres in the membrane pores and on the membrane surface of the membrane obtained in the step (3) to obtain the PVDF-SiO2 composite membrane. The uniformly-dispersed thiol-functionalized mesoporous silica microspheres are synthesized in the membrane pores and on the membrane surface of a large-pore base membrane in one step, and effective fixation of mesoporous silica in the membrane pores and on the membrane surface and penetration of the membrane pores and mesopores are realized, so that the obtained membrane has high stability and high heavy metal ion adsorption-desorption performance, and can be widely applied in the field of wastewater treatment.

An adsorbent suitable for heavy metal absorption is described, comprising a thiol-functionalised support containing a stabilising amount of an alkaline metal reacted with said thiol functionality. The adsorbent may be used to remove heavy metals e.g. mercury and/or arsenic, from wastewater streams such as produced water or flue gas scrubber waters.

The invention belongs to the technical field of heavy metal passivation, discloses thiol functionalized attapulgite and a preparation method thereof. The preparation method comprises: placing pre-treated attapulgite into a mixed solvent, and ultrasonically treating by using an ultrasonic wave system to uniformly disperse the attapulgite in the mixed solvent; carrying out pretreatment impurity removal on the raw attapulgite; dissolving gamma-trimethoxysilylpropanethiol (MTS) in absolute ethanol, and adding water and PEG400 to obtain a mixed solvent; carrying out a stirring reaction for 7-8 h ina stirrer, and carrying out centrifugal separation on the sample after the reaction to remove the upper layer aqueous solution and retain the solid-state substance; and washing the solid-state substance with distilled water to achieve a neutral state, and carrying out vacuum drying for 10-12 h at a temperature of 60-80 DEG C to obtain the thiol functionalized attapulgite. According to the presentinvention, the thiol is grafted by using the silane coupling method, such that the new approach is provided for the research and development of heavy metal contaminated soil passivating agents with advantages of large adsorption capacity, environmental friendliness and good adsorption selectivity.