319results about How to "Conducive to commercial production" patented technology

The present invention relates to extended release suspension compositions of an active ingredient. Said extended release suspension compositions comprise multiple coated cores of the active ingredient and a suspension base, wherein the suspension base generates a hypertonic condition such that there is no substantial change in the in-vitro dissolution release profile of the extended release suspension compositions upon storage for at least seven days. The invention also relates to processes for the preparation of said extended release suspension compositions.

The invention discloses a flexible high-strength MXene-based electromagnetic shielding composite film, which comprises a conductive layer Ti3C2Tx MXene/silver nanowire and a polymer enhancement layeraramid nanofiber, and is characterized in that the mass fraction of the Ti3C2Tx MXene/silver nanowire conductive layer is 10-80%; the mass ratio of the Ti3C2Tx MXene to silver nanowire is (10: 0.5)-(10: 1.5). The invention further discloses a preparation method of the flexible high-strength MXene-based electromagnetic shielding composite film. The composite film prepared by the invention has excellent flexibility and mechanical properties, good conductivity and broadband high electromagnetic shielding effectiveness, and can meet the application in the fields of aerospace, military engineering,artificial intelligence and flexible wearable electronic equipment.

The invention discloses a dual microsphere preparation of a hydrophilic drug, which consists of the hydrophilic drug, chitosan, sodium tripolyphosphate and a polylactic acid-glycolic acid copolymer. The invention also discloses a method for preparing the dual microsphere preparation: firstly, chitosan nanoparticles of the hydrophilic drug are prepared; secondly, the nanoparticles are dispersed in an acetonitrile or dichloromethane solution of PLGA and are evenly mixed to be used as suspension aqueous phase; finally, span80 is dissolved in edible oil to be used as oil phase; the oil phase is slowly dripped to the suspension aqueous phase while being stirred; acetonitrile or dichloromethane is removed; and the mixture is subjected to centrifugal collection and vacuum drying to prepare the dual microsphere preparation. The dual microsphere preparation of the hydrophilic drug has small burst effect, keeps the high encapsulation efficiency of the chitosan nanoparticles to the hydrophilic drug, is slowly released in vitro and is novel promising slow-release dosage of the hydrophilic drug.

The invention discloses a preparation method of a polymer foam-based multi-stage carbon nanocomposite pressure-sensitive material. The preparation method comprises the following specific steps: dispersing graphene oxide into deionized water, and performing ultrasonic dispersion to obtain a negatively charged aqueous graphene dispersion; performing a refluxing reaction on gamma-aminopropyltriethoxysilane in a toluene solvent protected by a nitrogen atmosphere to achieve surface aminosilane modification of hydroxylated carbon nanotubes, dispersing the aminosilane-modified carbon nanotubes into deionized water, and dropwise adding a hydrochloric acid solution for pH adjustment to obtain a positively charged aminosilane-modified aqueous carbon nanotube dispersion; immersing perforated polymerfoam into the aqueous graphene dispersion, repeatedly squeezing, taking out after saturation, and drying in a drying box to obtain a polymer foam-based graphene composite material; then immersing thepolymer foam-based graphene composite material into the aminosilane-modified aqueous carbon nanotube dispersion, gently squeezing repeatedly and then drying. By the preparation method, the obtained conductive composite foam material has good flexibility, resilience and pressure-sensitive response.

The invention discloses a benzothiazole derivative containing a triphenylethylene or tetraphenylethylene structure and having aggregation-induced emission property and a preparation method and application thereof. The preparation method comprises the following steps: with 2-amino-6-methoxybenzothiazole as a start raw material, performing a ring-opening reaction under an alkaline condition to generate 2-amino-5-methoxythiophenol; performing a ring-closing reaction with an aromatic aldehyde compound containing a triphenylethylene or tetraphenylethylene structure to obtain a methoxy-containing benzothiazole derivative, or performing demethylation to obtain a hydroxyl-containing benzothiazole derivative, wherein the compound also can be modified through a group substitution reaction to generate a benzothiazole derivative containing other functional groups. The benzothiazole derivative disclosed by the invention has relatively low luminous intensity in a solution, emits strong fluorescence in an aggregation state or solid state, and belongs to good aggregation-induced emission materials; the synthesis is relatively simple, and the cost of the raw materials is low, so that large-scale commercial production is easy to realize; the benzothiazole derivative plays an important role in the fields of electroluminescent devices, fluorescent probes, fluorescent switches, organism imaging and the like.

The invention discloses a direct methanol fuel cell capable of realizing pure methanol supply. The fuel cell comprises a cell shell, and a pervaporation membrane which is fixed on the cell shell and divides an inner chamber into a methanol fuel chamber and a steam chamber, wherein an anode flow field plate, a membrane electrode and a cathode flow field plate are sequentially arranged above the steam chamber from bottom to top in a stacking manner; a hollow cover plate covering a cathode collector plate is arranged at an open end of the cell shell in an insulation manner; a hydrophilic porous plate with hydrophily is arranged between the anode flow field plate and the anode side of the membrane electrode; a hydrophobic porous plate with hydrophobicity is arranged between the cathode side of the membrane electrode and the cathode flow field plate. According to the invention, continuous vaporization methanol supply is guaranteed, methanol crossover is restrained while cathode water is promoted to be reversely supplemented to the anode to participate in reaction, on the premise of guaranteeing output performance of the cell, the energy density of the cell is increased effectively, high-concentration methanol supply even pure methanol supply of the cell is realized and the service life of the cell is prolonged greatly.

The invention relates to a quinoline nitrile derivative. A method comprises the following steps of: reacting 2-methylquinoline serving as an initial raw material with the corresponding alkyl halide to obtain quaternary ammonium salt, performing Michael addition-elimination reaction on the quaternary ammonium salt and malononitrile, and performing Knoevenagel condensation reaction on the obtained compound and the corresponding aromatic aldehyde to obtain a target product. The aggregate or solid substance of the derivative has strong fluorescence and large wavelength, is a good aggregation-induced emission material, and has considerable application prospects in the fields of electroluminescent devices, fluorescent probes, intelligent materials, organism imaging and the like.

The present invention discloses activated carbon-metal organic framework composite materials (AC@MOF) with enhanced gas adsorption capacity. The present invention also discloses a process for the preparation of carbon-metal organic framework composite materials (AC@MOF). The present invention involves the use of “void space filling method” in metal organic frameworks (MOFs), which have been accomplished by in-situ addition of selected type and appropriate amount of activated carbon during the synthesis of MOF such as Cu-BTC, in the storage of gases such as methane. The gas adsorption capacity of these AC@MOF composite materials is significantly increased through this method.

The invention belongs to the field of tea technology, which relates to a new preparation method of calyx canthus flower tea. The invention has the characters of plucking the fresh sprouts or leaves of tea tree, drying to premiere green tea, processing the tea with the two-scenting technology, aromatizing, scenting, drying and flowers-removing. The calyx canthus flower tea, which is the product of this invention, has the typical smell of calyx canthus flower, can keep fresh for a long time, the tea liquor has the color of light yellow and green with fresh flavor, the tea leaves bottom has the color of light yellow and green. The calyx canthus flower tea not only has the beautiful shape of good tea, but also has the light scent of calyx canthus flower, a novel flower tea is provided for customers.

The invention relates to a method for synthesizing manganese phosphate lithium sol-gel doped with other metal ions. The method comprises the following steps: (1) dissolving a lithium source compound, a manganese source compound, a metal ion compound, a carbon source compound, a phosphorus source compound and a complexing agent in deionized water, wherein the molar ratio of the complexing agent to the lithium source compound is 0.5-2.5; (2) stirring a settled solution strongly and evaporating the solution until a viscous substance is obtained, and performing drying and ball milling on the viscous substance in a blasting drying box to obtain a mixed powder; and (3) transferring the mixed powder into a ceramic boat, and performing calcinations under the atmosphere of indifferent gas under the temperature of 500-800 DEG C for 1-24 hours to obtain a manganese phosphate lithium product doped with other metal ions. The method provided by the invention has the advantgages of improving the electric conductivity of materials effectively and largely improving the cycle performance of materials, has also the advantages of good evenness of the synthesized manganese phosphate lithium sol-gel doped with the other metal ions, low production cost, simple operation and easiness to realize commercialized production.

The present invention discloses a pharmaceutical composition for the treatment of cardiovascular and cerebrovascular diseases which comprises Radix Salviae Miltiorrhizae extract 5.0%-70.0%, Radix Notoginseng extract 10.0%-85.0%, Radix Astragali extract 5.0%-70.0%, and Bomeol or oil of Lignum Dalbergiae Odoriferae 1.0%-15.0%. The composition is active against cerebral ischemia and myocardial ischemia. The effects are superior to total phenic acid of Radix Salviae Miltiorrhizae or total saponin of Radix Notoginseng respectively, or the combination thereof. The composition of the invention can provide various kinds of preparations by the addition of various accessories. Thus the invention provides a more effective and convenient composition of TCM effective sections and its preparations.

The invention discloses a flexible photoinduced ultrasonic thin film transducer and a preparation method thereof. The ultrasonic thin film transducer comprises a flexible transparent substrate (120),a light absorbing layer (130) and a thermos-elastic layer (140) from top to bottom in sequence. The flexible transparent substrate (120) is transparent polydimethylsiloxanepolymers; the light absorbing layer (130) is carbon nanotubes; and the thermo-elastic layer (140) is polydimethylsiloxane polymers. The preparation method of the flexible photoinduced ultrasonic thin film transducer comprises the steps that a glass substrate is spin-coated with a polydimethylsiloxane agent, and the flexible transparent substrate is prepared; an aluminum oxide inorganic screening film deposited with a carbonnanotube filter cake is pressed onto the transparent polymer thin film prepared in the second step, the aluminum oxide inorganic screening film is peeled off, and a carbon nanotube thin film transferred with the light absorbing layer is obtained on a transparent polymer substrate; and a carbon nanotube thin film layer is spin-coated with the polydimethylsiloxane polymers, and the thermos-elastic layer is formed after solidification. After the thermo-elastic layer is solidified, the glass substrate is peeled off.

The invention relates to a preparation method of lithium iron phosphate. The preparation method comprises the following steps of: respectively providing a lithium source solution, a ferrous iron source solution and a phosphorus source solution, wherein the lithium source solution, the ferrous iron source solution and the phosphorus source solution are respectively obtained by dissolving a lithium source compound, a ferrous iron source compound and a phosphorus source compound in an organic solvent; mixing the phosphorus source solution and the ferrous iron source solution to form a first solution; adding the first solution to the lithium source solution to form a mixed solution at the heating temperature of 90-180 DEG C, and keeping the heating temperature; carrying out coprecipitation reaction on the lithium source compound, the ferrous iron source compound and the phosphorus source compound in the mixed solution to generate the lithium iron phosphate. The method disclosed by the invention can be used for fast synthesizing the lithium iron phosphate at lower temperature.

The invention discloses a preparation method for light calcium carbonate. In the method, a Ca(OH)2 turbid liquid and CO2 compressed gas respectively pass through two fluid atomizing spray nozzles, wherein the Ca(OH)2 turbid liquid is dispersed into micron-scale droplets by high-pressure CO2, and meanwhile, a carbonization reaction is carried out to generate the light calcium carbonate, which is rapidly dried by hot air flow to directly prepare light calcium carbonate powder. Compared with a conventional carbonization method, in the method, the Ca(OH)2 droplets, being a dispersion phase, and the CO2 gas, being a continuous phase, are contacted in forward direction, so that because the atomized Ca(OH)2 turbid liquid has small droplets, contact area of gas-liquid two-phase mass transfer is effectively increased. Meanwhile, gas-liquid mass transfer rate is increased since the Ca(OH)2 droplets have large speed difference from the CO2 gas, thereby completing the carbonization reaction in a short time. The sprayed droplets are rapidly dried by hot air flow after the carbonization reaction, thereby producing the light calcium carbonate powder.

The invention relates to a U-shaped plastic optical fiber liquid refractive index sensor with a multi-groove structure, and belongs to the technical field of optical fiber sensors. The U-shaped plastic optical fiber liquid refractive index sensor consists of a light source, a U-shaped plastic optical fiber probe with a multi-groove structure, and a photoelectric detection device. The U-shaped plastic optical fiber probe with the multi-groove structure is characterized in that a plastic optical fiber is vertically arranged at the lower surface of a steel die of which the surface provided with a cross section of a triangular sawtooth structure, and the vertexes of a triangle point to a center line of the plastic optical fiber; the pressure is applied to the steel die by a clamp, and the multi-groove structure with multiple V-shaped grooves is pressed along a fiber core of a centerline cross section of the plastic optical fiber by the triangular sawtooth structure of the die; then, the plastic optical fiber and the opposite other side surface of the multi-groove structure are wound on a cylindrical steel cylinder which is heated to about 75 to 95 DEG C; finally, about 3 to 6N tension is applied to both ends of the optical fiber. The U-shaped plastic optical fiber liquid refractive index sensor has the characteristics that the structure and preparation technology are simple, the cost is low, and the sensitivity is high.

The invention relates to a proton exchange membrane for a fuel cell, in particular to a combined self-humidifying proton exchange membrane for a self-humidifying fuel cell and a preparation method. The method comprises the steps of distributing loaded catalysts to organic solution of solid macromolecule electrolyte to form casting solution, then casting, coating, or tape casting are adopted to prepare the self-humidifying proton exchange membrane, or the casting solution is adopted with methods of casting, coating, or tape casting to be filled in a porous strengthening membrane to prepare theself-humidifying proton exchange membrane. The self-humidifying proton exchange membrane of the invention generates from non-electric short circuit in the whole membrane, and has the characteristics of good density, high proton conductivity, strong water retaining capacity, as well as low cost.

The invention discloses a preparation method of wintersweet longjing tea. The preparation method of the wintersweet longjing tea comprises the following steps: preparing a tea base, blending flavor, scenting, finally scenting, embedding fragrance and re-firing the wet base. According to the preparation method of the wintersweet longjing tea, the longjing tea base is instantly puffed under high pressure to break the wall of the tea base, so that the defect of low adsorption capability caused by a compact structure of pan-fired green tea is overcome, and the physical adsorption capability of efficiently adsorbing wintersweet flower fragrance of the longjing tea base is improved; chloranthus flowers are used as a base by two different manners, the lasting rich fragrance of the chloranthus flowers cooperates and coordinates with the rich fragrance of castanea mollissima fruits in the pan-fired green tea, and thus the fresh and elegant properties of the wintersweet fragrance are well foiled; water of wintersweet flowers is well evaporated while the fragrance is retained to a greatest extent, and the fragrance freshness of the scented tea is improved.

The invention discloses a benzothiazole lysosome-targeted pH fluorescent probe and preparation and application thereof. A preparation method of the probe comprises the steps that quinoline-4-formaldehyde, 2-methyl-benzothiazole and trimethylchlorosilane (TMSCl, serving as a catalyst) are dissolved into dimethylformamide according to the mole ratio of 1:1:10 in a sealed tube, the solution is heated to 100 DEG C, a reaction is conducted for 16 hours, and precipitates are filtered out; the precipitates are dissolved with dichloromethane, the pH value is regulated to be 8.0 with a NaCO3 solution, extraction is conducted with dichloromethane, drying and recrystallizing are conducted, and the pure product is obtained. The probe has the large Stokes displacement (110 nm) and has the high sensitivity and selectivity on H<+> changes. The pKa value is 3.52, and the pH linear range is 3.0-3.8. A laser co-focus experiment shows that the probe can be positioned to a lysosome in a targeted mode and makes a response for pH changes of the lysosome in a weak acid environment. In addition, the probe can detect pH changes in escherichia coli in a highly acidic environment (the pH value is smaller than 4) in a highly sensitive mode.

The invention relates to a method for preparing a lithium manganese phosphate positive material of a lithium battery by spray pyrolysis and belongs to the technical field of the positive materials of lithium batteries. According to the method, homogeneous nucleation of lithium manganese phosphate is promoted through the high-temperature spray pyrolysis under the condition of an inert atmosphere, so as to reduce the temperature and the time of the follow-up reaction to obtain the lithium manganese phosphate positive material with excellent electrochemical performance. The method disclosed by the invention is simple; and since raw materials are mixed in molecular ion level and the temperature and the time of the follow-up reaction are reduced after the high-temperature spray pyrolysis, the obtained lithium manganese phosphate material has the advantages of high purity, complete crystal structure, fine and uniform particles and the excellent electrochemical performance.

The invention discloses a dielectric ceramic material with a giant dielectric constant and low dielectric loss. The dielectric ceramic material is a SrTiO<3>-based ceramic material with giant dielectric performance, a Sr bit of the SrTiO<3>-based ceramic material is jointly substituted by two elements Sm and Ba, a chemical formula of the dielectric ceramic material is Ba<x>Sr<0.97-x>Sm<0.02>TiO<3>, and the x represents a mole fraction of the element Ba, is larger than or equal to 0.1 and is smaller than or equal to 0.4; a fixed mole fraction of the element Sm is 0.02. A method for preparing the dielectric ceramic material includes steps of mixing SrCO<3>, SM<2>O<3>, TiO<2> and BaCO<3> with one another according to a stoichiometric ratio of the chemical formula Ba<x>Sr<0.97-x>Sm<0.02>TiO<3> to obtain mixtures; carrying out ball-milling on the mixtures; drying the mixtures; pre-sintering the mixtures; carrying out secondary ball-milling on the mixtures; granulating the mixtures; molding the mixtures; sintering the mixtures and the like to obtain the dielectric ceramic material. The dielectric ceramic material and the method have the advantages that the dielectric ceramic material is high in dielectric constant (higher than 20000), low in dielectric loss (lower than 0.05) and excellent in temperature and frequency stability; the method is simple and is good in repeatability, high in yield, low in cost and suitable for popularization and application.

The present invention discloses a perennial forage maize breeding method. Experiments prove that the character of high seed rate from hybridizing diploid maize and tetraploid Zea perennis is a heritable dominant character. On the basis, the present invention provides a method for breeding Zea mays L. with high seed rate which is hybridized with Zea perennis, the F1 generation of Zea mays L. obtained by the method is used as a female parent, tetraploid Zea perennis is used as a male parent for artificial hybridization, and the obtained hybrid seeds of F1 generation are perennial forage maize seeds. The perennial forage maize bred by the method has the characteristics of short breeding cycle, easiness in operation and high seed yield, and has broad application prospects in production.