33results about How to "Effective content control" patented technology

The invention provides erbium strengthened magnesium-lithium alloy and a preparation method thereof. The magnesium-lithium alloy prepared through the following method comprises, by mass, 5%-11% of Li, 0.5%-10% of Er, not more than 5% of Al and the balance magnesium and inevitable impurity elements. The preparation method comprises the steps that (1) smelting is conducted under the condition of vacuum or protective atmosphere after component proportioning is designed according to the alloy elements, and then an alloy ingot is poured; (2) homogenization treatment is conducted at the temperature of 200 DEG C-500 DEG C, and the homogenization treatment time is 0.5-10 h; (3) multi-pass rolling is conducted at the temperature of 250 DEG C-400 DEG C, and the total reduction rate is 20%-90%; and (4) two times of aging treatment can also be conducted before and after rolling. According to the erbium strengthened magnesium-lithium alloy and the preparation method thereof, the alloy components, the two times of aging treatment temperature, the treatment time, the cooling process, the hot rolling temperature, the hot rolling passes and the deformation parameters are controlled, so that the grain size of the erbium strengthened magnesium-lithium alloy is refined, and the mechanical property is improved.

The invention relates to a treatment agent of removing harmful metal elements from the surface of a catalyst, wherein the treatment agent includes following components, by mass, 0.1-10% of disodium ethylene diamine tetraacetate, 0.1-15% of sulphamic acid or / and sulfosalicylic acid, 0.005-0.1% of aspartic acid or / and polyepoxysuccinic acid, 0.01-0.5% of a surfactant and the balanced being water. The invention also relates to a method of removing the harmful metal elements from the surface of the catalyst with the treatment agent. The method is simple and available. The catalyst can be soaked completely in the treatment agent, so that the harmful metal elements in the catalyst are directly subjected to a chemical reaction with the treatment agent in liquid phase, wherein generated substances are dissolved in the treatment agent, so that the harmful metal elements can be high-effectively removed under the situation of not changing the content and distribution of the active elements on the surface of the catalyst, thereby effectively controlling the content of the harmful metal elements on the surface of the catalyst for maintaining the activity and the catalytic reforming performance of the catalyst.

The invention belongs to the technical field of medicinal chemistry, and specifically relates to canagliflozin impurities, preparation and removal methods. The canagliflozin impurities disclosed in the present invention are produced during the production process of canagliflozin, and the disclosed impurities can be canagliflozin The quality control of net intermediates provides qualified impurity reference substances. The impurity removal method provided by the present invention can effectively improve the purity of the canagliflozin intermediate, and the purity of the intermediate can reach 99.91%, thereby improving the purity of the canagliflozin product. The canagliflozin impurity reference substance can be developed for the canagliflozin process The monitoring of this impurity in the drug provides an important reference basis and improves the quality monitoring level of canagliflozin.

The present invention discloses one kind of composition containing calcium conjugate linoleate for increasing the milk output of milk cow and its preparation process. The composition is prepared with vegetable oil as material, and through ester exchange reaction, molecular distillation, saponification, isomerization and metathetical reaction. It consists of alphatic calcium, water and impurity salt; and the alphatic calcium includes calcium conjugate linoleate accounting for 82-90 wt% of the composition, calcium palmitate, calcium stearate, calcium oleate and calcium linoleate accounting for 8-15 wt% of the composition. It has high calcium conjugate linoleate content, controllable content of other kinds of alphatic calcium and excellent physical character. It is used in raising milk cow to raise milk output obviously.

The invention aims at providing a preparation method of bromfenac sodium sesquihydrate. The preparation method comprises the following steps: (1) adding bromfenac sodium and an antioxidant into a mixed solvent of water and an organic alcohol, heating, dissolving and adding a pH adjustor to adjust the pH to 7.0-10.5; (2) adding an anti-solvent into a solution obtained in the step (1), cooling the solution to 30 DEG C to 35 DEG C, adding bromfenac sodium monohydrate, bromfenac sodium sesquihydrate or a mixture thereof as a seed crystal, and stirring; and (3) cooling, crystallizing, collecting crystals and drying to obtain the bromfenac sodium sesquihydrate. The preparation method avoids use of ether agents and is mild in reaction condition and good in environmental benefit. The prepared bromfenac sodium sesquihydrate is high in purity.

The invention discloses a preparation method of low-dysprosium corrosion-resistant sintering neodymium iron boron. According to the preparation method, Dy, Co, Al and alloy elements such as Cu, Ga and Nb are sputtered on the surface of airflow grinding powder by utilizing a magnetron sputtering-based powder coating process on the basis of preparing Nd(Pr)-Fe-B alloy powder, crystal boundary modified elements such as Co, Al, Cu, Ga and Nb are introduced while the Dy element is introduced into crystal boundary, and the temperature of the subsequent heat treatment process is reduced, so that the alloyed elements are dispersed properly near the crystal boundary in a sintering process, coercivity is improved, the Dy content is reduced, the corrosion resistance of a magnet is effectively improved, and preparation of the low-dysprosium corrosion-resistant sintering neodymium iron boron is realized.

The present invention provides a purification method of everolimus. Everolimus is derivatized, separated, and then hydrolyzed, and the content of impurity rapamycin in the treated everolimus is greatly reduced. Further, the product with higher purity can be obtained at a higher yield through one-time preparation of liquid phase purification, thereby reducing the industrial cost of the purification step; the application further provides a preparation method of everolimus, which has a high yield and is easy to operate. Simple and suitable for industrial production.