The invention discloses a synthesis method and application of biodegradable high-molecular-weight
polyester, and belongs to the field of
polyester synthesis. 2, 6-
pyridine dicarboxylic acid and a dihydroxyl compound are used as raw materials, and a series of novel biodegradable high-molecular-weight polyesters are synthesized by adopting a melt
polymerization method. The synthesis method comprisesthe following steps: under the protection of N2, stirring the raw materials at 160-185 DEG C under the action of a catalyst to react for 4.0-5.0 hours, heating to 200-220 DEG C, reacting for 2.0-3.5hours in a 5-15 KPa environment, and vacuumizing for 2.0-3.0 hours to obtain a
polymer crude product; cooling the crude product, adding
chloroform, dissolving, filtering, and adding
ethanol or
propanol and other low-carbon alcohols into the filtrate until no precipitate is generated; centrifugally filtering, washing the obtained precipitate with
ethanol to remove impurities, and carrying out
vacuum drying at 50-60 DEG C for 3.0-4.0 hours to obtain the required high-molecular-weight
polyester. The weight-average molecular weight Mw value of the obtained polyester is 210,000 280,000 Da, and themolecular
weight distribution Mw / Mn value is as wide as 3.0-4.9. The high-molecular-weight polyester prepared by the invention can be used as a main component of a medical material
surgical suture andcan also be used as a flexible and foldable curved display panel base material.