The invention discloses a high-performance grouting material for prefabricated buildings, which comprises the following raw materials in percentage by weight: a composite cementing material: 26-32% ofcement, 3-5% of fly ash, 2-5% of silica powder and 3-5% of slag powder, graded fine sand: 10%-13% of river sand of 20-40 meshes, 23%-30% of river sand of 40-70 meshes, 10%-18% of river sand of 70-140meshes and 2.5%-4.95% of quartz powder, auxiliary agents: 1%-2.5% of a water reducing agent, 0.3%-1.5% of an early strength agent, 0.5%-1.0% of a defoaming agent, 0.47%-3.0% of an expanding agent and0.05%-0.2% of a thickening agent, and a performance regulator: 0.05%-0.2% of a nano modified material and 0.03%-0.1% of a dispersing agent. The high-performance grouting material for prefabricated buildings has the advantages of early strength, quick hardening, quick and stable strength development, high flowability, micro expansion, no shrinkage, high breaking strength and fracture toughness, low cost and the like.