The invention provides a horizontal sand mill of a combined rotary dispersion disk grinding structure. The horizontal sand mill of the combined rotary dispersion disk grinding structure is composed of a machine frame, a motor, a main shaft, a grinding unit, a material pump and an electric system. The grinding unit is of the rotary dispersion disk grinding structure combining a crescent round dispersion disk and an eccentric dispersion disk, and is composed of an outer grinding cavity barrel body, an inner grinding cavity barrel body, the main shaft, a discharge separation device, a discharging end sealing cover, an abrasion-resistant plate, a barrel end sealing cover plate and a ball discharging valve. The horizontal sand mill of the combined rotary dispersion disk grinding structure has two different shearing forces and can change the movement mode of balls and materials in the barrel bodies, thereby increasing the relative movement speed and impact probability of balls and material particles, obtaining higher relative movement speed and impact force compared with a single round disk or eccentric disk, enabling materials to reach the ideal fineness as soon as possible, and obtaining higher grinding efficiency. The horizontal sand mill of the combined rotary dispersion disk grinding structure further has abrasion resistance and corrosion resistance, is long in service life, is convenient to clean and replace, and is widely applied to processing and production of paints, ink, pigment and other fields.