The invention discloses a biological degradation method and degradation device for animal carcasses. The degradation method comprises the following steps of 1 raw material smashing, wherein animal carcass raw materials needing to be treated are smashed into blocks through a smashing machine; 2 high-temperature sterilizing and one-time degrading, wherein the smashed animal carcass raw materials are conveyed into a decomposition tank, high-temperature sterilizing bacteria and auxiliary materials for adsorbing oil and fat are added into the tank, then the decomposition tank is sealed and heated to 120 DEG C or above, stirring is performed in a timing mode in the heating process, standing is performed for 10-14 hours, and then the materials are discharged; 3 secondary degrading, wherein composting fermentation is performed on the animal carcass raw materials processed through high-temperature sterilizing and one-time degrading to complete secondary degrading. According to the method, sterilizing is safe and thorough, sterilizing, decomposing and waste gas condensing and recycling of the animal carcasses are achieved at a time in the decomposition tank, the application range is wide, produced organic fertilizer cannot damage crops, the technology is reasonable, operation is easy and convenient, and energy conversation and environmental protection are achieved.