11 results about "Haloacetic acids" patented technology

The present invention provides an industrially desirable production method for a sulfone derivative that is useful as a herbicide, and an intermediate thereof.

The invention relates to a method for determining haloacetic acid in different water qualities through liquid-liquid extraction derivative gas chromatography, and belongs to the technical field of water quality analysis and detection.According to the method, at least one gas chromatograph, a sampling bottle with a plug, an extraction bottle with a plug, a derivative bottle with a plug, a microsyringe, a vortex oscillator and a heating block are used for determination of the method, the method mainly comprises the test steps of water sample collection, water sample extraction, water sample derivation, water sample determination and optimization detection, wherein optimization items mainly comprise a strong electrolyte, a volume ratio of sulfuric acid to methanol, instrument working conditions and the like. The method realizes detection of haloacetic acid in different water qualities, is high in sensitivity, good in accuracy and high in precision, and is suitable for drinking water, seawater, lake water, industrial wastewater and the like.

Process for the preparation of menthanecarbaldehyde, comprising the following steps: - Reaction of menthone with a haloacetic acid ester of the formula XCH2COOR, with X = chlorine or bromine and R = methyl or ethyl, to form the ester of menthaneglycitic acid, - Reaction of the ester of menthaneglycitic acid thus prepared to menthanecarbaldehyde, wherein, in order to react the prepared ester of menthaneglycitic acid to menthanecarbaldehyde, the ester is reacted with a strong base such that the ester is hydrolyzed, and the hydrolysis product, as menthaneglycitic acid or as a salt of menthaneglycitic acid, is decarboxylated after intermediate isolation or without intermediate isolation.

The invention discloses an antibacterial thermosetting coating / plastic system derived from phenoxy resin and capable of being degraded to original resin in a weak base mode, which is prepared by the following steps: dissolving phenoxy resin and haloacetic acid in a water-carrying agent, reacting at 80-130 DEG C for 1-12 hours, continuously separating generated water in the process, and after the reaction is finished, evaporating and precipitating to obtain the antibacterial thermosetting coating / plastic system. The halogenated acetic acid esterified phenoxy resin is obtained; mixing the obtained halogenated acetic acid esterified phenoxy resin with a poly-tertiary amine compound, and curing in a mold at 40-100 DEG C for 1-10 hours to obtain a thermosetting polymer; compared with the traditional phenoxy resin, the material prepared by the invention has the characteristics of organic solvent resistance, intrinsic antibiosis, degradability and the like, and the composite characteristic can enrich the application scene and the application range of the phenoxy resin.

The invention discloses a novel graphene oxide adsorption film and application thereof, and belongs to the technical field of film separation. Comprising the following steps: mixing a graphene oxide ethanol dispersion liquid with an RCC3 molecular cage aqueous solution, and carrying out ultrasonic dispersion and constant-temperature stirring reaction, so that a secondary amine group in a molecular cage and an epoxy group on the surface of graphene oxide are subjected to a nucleophilic ring-opening reaction, and covalent linkage is realized; and then coating the functionalized suspension on a porous membrane substrate to form an adsorption layer, carrying out protonation treatment through vacuum filtration of a hydrochloric acid solution, and finally drying and curing to obtain a finished product. The membrane can efficiently and selectively adsorb haloacetic acid disinfection byproducts (the rejection rate is greater than or equal to 90%) in drinking water, meanwhile, beneficial inorganic salt ions such as calcium, magnesium and sodium are allowed to permeate (the transmittance is greater than or equal to 80%), and high flux, high selectivity and anti-swelling stability are effectively considered. The preparation process is simple and controllable, is suitable for waterworks, underground water purification, industrial wastewater treatment and other scenes, and has significant industrialization potential.

This invention discloses a method for the electrocatalytic hydrogenation dehalogenation of haloacetic acids or halomethanes in water. A conductive material surface-modified with ruthenium or platinum is used as the catalytic cathode, and water is used as the hydrogen source to electrochemically hydrogenate and dehalogenate haloacetic acids or halomethanes in water into acetic acid or methane. The precious metals in the catalytic cathode of this invention are cheaper; the unit price of ruthenium is much lower than that of palladium and rhodium. Compared with palladium-modified catalytic cathodes, the dechlorination selectivity is higher, with an 11.7% increase in the selectivity for the hydrogenation and dechlorination of trichloroacetic acid in water to acetic acid.

The application relates to the technical field of organic synthesis and pharmaceutical intermediates, in particular to a (2S, 4R)-1-Fmoc-4-(O-allyloxycarbonylmethyl)-proline and a synthesis method thereof. The method comprises the following steps: performing silicon-based protection on (2S, 4R)-4-hydroxypyrrolidine-2-carboxylic acid; refluxing and dehydrating the alkyl aldehyde to construct a tetrahydropyrrolooxazolone bicyclic intermediate; after the silicon-based group is removed, etherification is performed with 2-haloacetic acid allyl ester under strong alkali to introduce a side chain; and finally, acid ring-opening hydrolysis and Fmoc protection are performed to obtain the target product. The amino group and the carboxyl group are protected in situ by constructing a bicyclic structure, the sensitive allyloxycarbonylmethyl side chain is introduced in a non-water system, and the hydrolysis of the side chain ester bond is effectively avoided. The product prepared by the application has high purity and good stereoselectivity, and an efficient and low-cost industrialization approach is provided for the synthesis of high-performance polypeptide blocks.

The invention discloses a method for monitoring the concentration of a water body disinfection by-product DBPs based on electron donating ability, and belongs to the technical field of environmental engineering.The method comprises the steps that S1, a water body sample is collected, first pretreatment is conducted, and the EDC value is measured through an ABTS + free radical reduction decolorization method; s2, carrying out second pretreatment on the water body sample subjected to the first pretreatment, and measuring the concentrations of trihalomethane and haloacetic acid in the water body sample by utilizing a gas chromatographic method; s3, by taking the EDC value as an independent variable and the trihalomethane concentration and the haloacetic acid concentration as dependent variables, establishing a first prediction model for predicting the trihalomethane concentration based on the EDC value and a second prediction model for predicting the haloacetic acid concentration based on the EDC value; and S4, predicting the concentration of trihalomethane and the concentration of haloacetic acid by using the first prediction model and the second prediction model based on the EDC value of the target to-be-detected water body sample. The method solves the problems that a traditional DBPs detection method is long in time consumption and complex in operation.

The invention discloses application of haloacetic acid in enrichment of small molecule nucleic acid in a biological sample, and belongs to the technical field of molecular biology. According to the application, the haloacetic acid is utilized to enrich the micromolecular nucleic acid in the liquid biological sample, so that not only can the influence of interferents be eliminated, but also the enriched micromolecular nucleic acid sample can be stably stored at room temperature, and the micromolecular nucleic acid sample can be directly subjected to amplification detection without being extracted, so that the application value is very important.

The invention relates to the technical field of organic synthesis and medical intermediates, in particular to (2S, 4R)-1-Fmoc-4-(O-allyloxycarbonyl methyl)-proline and a synthesis method thereof. The method comprises the following steps: carrying out silicon group protection on (2S, 4R)-4-hydroxypyrrolidine-2-carboxylic acid; carrying out reflux dehydration on the tetrahydropyrrolo-oxazolone and alkyl aldehyde to construct a tetrahydropyrrolo-oxazolone bicyclic intermediate; after removing a silicon base, etherifying with 2-halogenated allyl acetate under strong base to introduce a side chain; and finally, carrying out acidic ring-opening hydrolysis and Fmoc protection to obtain a target product. According to the preparation method, amino and carboxyl are subjected to in-situ protection by constructing a bicyclic structure, and a sensitive allyloxycarbonyl methyl side chain is introduced by utilizing an anhydrous non-aqueous phase system, so that hydrolysis of ester bonds of the side chain is effectively avoided. The prepared product is high in purity and good in stereoselectivity, and an efficient and low-cost industrial approach is provided for synthesis of high-performance polypeptide building blocks.

The application discloses a method for electrocatalytic hydrogenation dehalogenation of haloacetic acid in water by using a ruthenium / nickel hydroxide catalyst, wherein a conductive material with a surface modified ruthenium / nickel hydroxide is used as a catalytic cathode, the cathode potential is-0.3~‑1.0 V vs. silver / silver chloride reference electrode, and water is used as a hydrogen source, so that the haloacetic acid in water is electrochemically hydrogenated and dehalogenated into acetic acid. Under the condition of the same Ru loading, the catalytic activity of Ru / Ni(OH)2 is higher, the conversion rate of trichloroacetic acid is 9% higher, the acetic acid yield is 14% higher, and the acetic acid selectivity is 5% higher.