54 results about "Ketone synthesis" patented technology

The invention relates to the technical field of medicine, and discloses a continuous flow primidone synthesis reaction temperature accurate regulation and control system and method, and the method comprises the steps: analyzing the reaction characteristics of a primidone synthesis reaction, identifying the optimal temperature interval of the primidone synthesis reaction, and configuring a continuous flow reactor of the primidone synthesis reaction; the method comprises the following steps: extracting temperature distribution characteristics of a continuous flow reactor, and arranging a multi-point temperature monitor for synthesis reaction of primidone in the continuous flow reactor; in combination with the target temperature of the continuous flow reactor and the real-time temperature of the synthetic reaction of the primidone, creating a temperature anomaly feedback node of the synthetic reaction of the primidone; analyzing a temperature fluctuation rule of the synthesis reaction of the primidone, and setting an automatic temperature adjusting mechanism of the synthesis reaction of the primidone; and in combination with a multi-point temperature monitor, an automatic temperature regulation mechanism and a temperature anomaly feedback node, performing temperature regulation and control treatment on the primidone synthesis reaction to obtain a temperature regulation and control result. According to the method, the product quality and yield of the synthesis reaction of the primidone can be improved.

The invention relates to the technical field of anion exchange membranes, in particular to a dual-ion-channel synergistic enhanced conduction anion exchange membrane for alkaline water electrolysis hydrogen production and a preparation method of the dual-ion-channel synergistic enhanced conduction anion exchange membrane for alkaline water electrolysis hydrogen production, and the dual-ion-channel synergistic enhanced conduction anion exchange membrane for alkaline water electrolysis hydrogen production is prepared by blending and crosslinking quaternized polyether-ether-ketone and carboxylated polyether sulfone, the carboxylated polyethersulfone provides a cation channel to form a double-ion synergistic conduction structure; the preparation process of the anion exchange membrane comprises the steps of quaternized polyether-ether-ketone synthesis, carboxylated polyether sulfone synthesis, membrane casting solution preparation, tape casting drying, crosslinking treatment and alkali liquor ion exchange. By constructing a double-ion channel structure, the synergistic conduction of anions and cations is realized, and the total ion conduction efficiency of the membrane is remarkably improved. The two polymer components form a continuously interlaced channel network, so that the defect that the conduction path of the traditional single ion channel membrane is isolated is avoided.

The synthesis process comprises the following steps: (1) introducing inert gas into a reactor, adding a solvent, a Lewis acid catalyst and diphenyl ether, then dropwise adding an acyl chloride monomer solution, and synthesizing an intermediate M with a short-chain small molecular structure; (2) continuously dropwise adding an acyl chloride monomer solution into the reactor for reaction, and then adding an end-capping reagent for reaction; and (3) quenching, washing and drying the reaction product in the step (2) to obtain the product. Under the condition that only the Lewis acid is used as the catalyst, the one-pot method is adopted for synthesizing PEKK in two steps, side reactions can be reduced, meanwhile, the dosage of the catalyst is reduced, the production cost is reduced, the post-treatment process is simplified, and the obtained polyether ketone ketone is high in molecular weight and good in heat resistance and mechanical performance.

The invention provides a method for synthesizing a hydroxyl-protected alpha-hydroxy aldehyde compound by electrically reducing aromatic ketone, which comprises the following steps of: adding aromatic ketone, a formylation reagent, an additive and electrolyte into a reaction electrolytic tank, adding a reaction solvent in an inert gas atmosphere, tightly covering a plug with an electrode, and carrying out electrolytic reaction to obtain the hydroxyl-protected alpha-hydroxy aldehyde compound. And separating and purifying to obtain the hydroxyl-protected alpha-hydroxy aldehyde compound. Clean electrons are used as a reducing reagent, no transition metal residues exist, raw materials are simple and easy to obtain, reaction conditions are mild, and the method has wide substrate universality and high operability, is a green and economical synthesis method, has extremely high potential industrial prospects and has high commercial application value.

The invention discloses a method for synthesizing 1-methoxy-2-acetone from high-entropy alloy CoNiMnMoCu through electro-catalysis of 1-methoxy-2-propanol, and belongs to the technical field of electro-catalytic synthesis of organics. The high-entropy alloy CoNiMnMoCu synthesized by transition metal is used as an anode electro-catalyst in an alkaline electrolyte, electro-catalytic oxidation is carried out under indoor natural conditions, and the 1-methoxy-2-acetone is obtained. After the reaction is finished, extraction separation and distillation purification are performed, and the purified target product is 1-methoxy-2-acetone. The invention provides a green and efficient synthesis method of 1-methoxy-2-acetone, and a foundation is laid for industrialization of alcohol and aldehyde electrooxidation appreciation in the future.

The utility model relates to separation and extraction equipment for 2, 4-dichloro-5-fluoroacetophenone synthetic liquid, which is applied to the technical field of extraction and separation equipment, and realizes that after a scraper blade is turned upwards by 90 degrees, a material is placed in a tray, then the tray is sleeved on a mounting shaft, the bottom is placed on a bracket to support the bottom, and at the moment, the scraper blade is turned and reset, so that the material is separated from the material. The scraping teeth are located in the trays and make contact with the bottoms of the scraping teeth, then the first clamping block at the bottom of the other mounting shaft is clamped in the inserting groove in the top of the lower mounting shaft to be clamped and fixed, the upper mounting shaft is sleeved with one tray containing the materials again, and multiple layers of the trays can be sequentially placed to dry the materials; and at the moment, a heater and a servo motor are started, the heater dries the materials, the servo motor drives a scraper to rotate, the materials in the tray are turned over, the materials can be evenly heated in the drying process, and the problem that part of the areas are excessively dried, and part of the areas are not fully dried is avoided.

The invention relates to a method for synthesizing an iodo-pyridine compound from N-propargyl enaminone, which comprises the following steps: by taking N-propargyl enaminone as a raw material, DMF (Dimethyl Formamide) as a reaction solvent and copper acetate and N-iodosuccinimide as accelerators, carrying out intramolecular coupling reaction at 60 DEG C to synthesize the iodo-pyridine compound. The method for directly synthesizing the pyridine heterocyclic compound through the intramolecular coupling reaction of the N-propargyl enaminone under the non-alkaline condition is disclosed for the first time, reaction substrates are not limited to benzene rings on alkynyl, the application range of the reaction is greatly expanded, and the method has the advantages of being wide in substrate range, strong in functional group application range, mild in reaction condition, easy to operate, safe, high in yield and the like. And raw materials are cheap.

The invention discloses a synthetic carbamate compound based on 3-substituted dioxazolone as well as a preparation method and application of the synthetic carbamate compound, and belongs to the technical field of organic synthesis. The synthesis method comprises the following steps: (1) preparing 3-substituted dioxazolone from hydroximic acid with different substituent groups and phosgene under an ice bath condition; and (2) reacting the 3-substituted dioxazolone obtained in the step (1) with different phenols (alcohols) under an alkaline condition to obtain corresponding carbamate compounds. According to the method, the yield of carbamate is further improved by adjusting the conditions of alkali, equivalent weight, temperature and the like; the preparation method provided by the invention is novel and has the advantages of mild reaction conditions, few generated impurities, high yield, high safety, convenience in operation and the like; and the compound shows good cholinesterase activity in activity screening, and can be used in insecticides or pesticides.

The present disclosure relates to a process of preparation of 2-amino alcohol of formula I comprising: i) reacting 2-hydroxyketone or 2-hydroxyaldehyde of formula II in presence of an aminating agent and a solvent under condition to obtain imine intermediate; and ii) processing by hydrogenation the imine intermediate in presence of a metal catalyst and H2 under condition to obtain 2-amino alcohol of Formula I.

The invention relates to a novel method for synthesizing dichloropyridazinone, which is characterized in that the pyridazinone is generated through the reaction of tert-butylhydrazine and furfuryl acid under the condition of a non-water-soluble organic solvent by changing the initial raw materials of the reaction, the reaction product acetic acid can be recycled, and the reaction solvent and the subsequent synthesis of pyridaben are the same solvent, so that the desolvation process and the crystallization process are omitted, and the yield is improved. The method avoids high-temperature decomposition of a heat-sensitive material intermediate dichloropyridazinone, greatly improves the production field environment, effectively improves the comprehensive yield of a finished product, and is more suitable for industrial production.

The utility model discloses a constant temperature storage device for ketone synthesis process sample research, which relates to the technical field of constant temperature storage and comprises a storage box. The switch is extruded when the extrusion plate rotates downwards, the thermostat is automatically and temporarily closed when the switch is extruded, the thermostat is prevented from continuously dissipating high temperature, an expansion mechanism of the air bag can be automatically triggered when the temperature is too high, the thermostat is closed in time, further temperature rise caused by continuous heating of equipment is prevented, and the safety of a sample is guaranteed; a physical protection means is provided, unforeseen circumstances can be effectively handled, the equipment failure risk is reduced, when the temperature exceeds a safety threshold value, the thermostat is cut off in time, unexpected chemical reaction of a sample at the high temperature can be prevented, and therefore the accuracy of experimental data and the integrity of the sample are protected.

The utility model relates to the technical field of synthesis of methyl isobutyl ketone, and discloses a feeding device for synthesis of methyl isobutyl ketone, which comprises a main body mechanism and a quantifying mechanism and is used for conveying metered materials to a processing area. According to the feeding device for synthesis of methyl isobutyl ketone, the feeding port and the conveying pipe are arranged on the feeding bin, liquid, solid and gas materials can be added at the same time, various process requirements are met, the pressure gauge and the pressure sensor are further arranged at the upper end of the feeding bin, the pressure change in the bin can be monitored in real time, and the safety and stability of the operation process are ensured; the metering hopper is connected with the feeding bin and the discharging pipe through hoses, mobility is provided, the weighing process is prevented from being affected by fixed connection, the hoses are fixed to all parts through pipe hoops, firmness and sealing performance of connection are guaranteed, and the weighing device is suitable for long-time operation.

The invention provides a synthesis method of benzyl oxygen-18 labeled aromatic aldehyde or aromatic ketone, and relates to the technical field of organic chemical synthesis. In an inert atmosphere, a benzyloxy-18-labeled aromatic aldehyde or aromatic ketone is obtained by dissolving a benzyloxy-18 substrate, an electrolyte, an alkaline additive and oxy-18 water in an organic solvent, carrying out an electrochemical oxidation reaction and then carrying out separation and purification. According to the method, a green electrochemical strategy is adopted, no transition metal participates, the reaction conditions are mild (normal temperature and normal pressure), the oxygen isotope labeled aromatic aldehyde or aromatic ketone compound is directly synthesized in one step without pre-synthesizing an aldehyde / ketone precursor, the substrate application range is wide, various substituent groups such as halogen, alkyl and aryl can be compatible, and the method is suitable for industrial production. And electron-deficient aldehyde ketone which is difficult to mark by a traditional method can be synthesized. The synthesized product can be used in the fields of drug metabolism research, environment tracking and the like, and has the advantages of step economy, green synthesis and industrialization potential.

The invention discloses a peach ketone synthesis method, which relates to the technical field of essence and perfume synthesis, and comprises the following steps: adding cyclopentanone and glacial acetic acid into a reaction container, starting stirring, adding manganese acetate (II) and cobalt acetate (II), and then adding acetic anhydride; introducing dried air below the liquid level, heating to 80-100 DEG C, dropwise adding D-limonene, and carrying out a heat preservation reaction after dropwise adding is finished; gC monitors the reaction endpoint, and the reaction is stopped when the product purity of the reaction liquid is not increased any more; after the reaction is finished, filtering, carrying out reduced pressure distillation to recover cyclopentanone, glacial acetic acid and unreacted D-limonene, after the recovery is finished, adding methanol and n-heptane into kettle liquid, carrying out water extraction, washing and liquid separation, washing an organic phase with a sodium bicarbonate aqueous solution, carrying out reduced pressure distillation on the organic phase to recover n-heptane, and after the recovery is finished, obtaining a peach ketone crude product; and carrying out crude drawing and rectification on the peach ketone crude product to obtain a peach ketone finished product. The method has the advantages of mild reaction conditions, low safety risk and few three wastes, and can obtain a high-purity peach ketone finished product.

The invention discloses a novel process for synthesizing N-vinyl pyrrolidone, and provides a preparation method of N-vinyl pyrrolidone, which is efficient, low in cost and energy-saving. Raw materials of alpha-pyrrolidone and a catalyst potassium salt react in a high-vacuum reactive distillation tower, the reaction temperature is controlled, the reaction product water is distilled out from the tower top, and the generated alpha-pyrrolidone potassium salt is buffered by a buffer tank and then sent to an N-vinyl pyrrolidone reactor. In order to ensure the stable supply of acetylene in the synthesis reaction of N-vinyl pyrrolidone, a method of supplementing nitrogen with a surge tank is adopted to maintain the stability of the system. And carrying out low-pressure flash evaporation on the reacted N-vinyl pyrrolidone gas-liquid product through a surge tank, recycling the gas phase, and obtaining the N-vinyl pyrrolidone crude product from the liquid phase. According to the process, the conversion per pass of the alpha-pyrrolidone can reach 55%, the purity of the N-vinyl pyrrolidone is greater than or equal to 98%, and the energy consumption is reduced by 20%.

The present invention provides a method for synthesizing perfluorohexanone from hexafluoropropylene, belonging to the field of fluorine-containing ketone synthesis. This method synthesizes perfluorohexanone through four steps, specifically: step one, a hexafluoropropylene oligomerization reaction, in which HFPD is synthesized using a non-protonic polar solvent, a metal fluoride, and an organic cesium co-catalyst as raw materials; step two, an isomerization reaction; step three, an epoxidation reaction, in which perfluoroepoxide is synthesized under the action of an oxidant; and step four, a ketone reaction, in which perfluoroepoxide is ketoneized in a polar non-protonic solvent and a metal fluoride to obtain perfluorohexanone. The method has high perfluorohexanone raw material conversion rate and reaction product selectivity, low raw material cost, simple process, and greatly improved purity of perfluorohexanone.

The invention relates to the technical field of perfume synthesis, in particular to an efficient hydrolysis process in perfume synthesis, which comprises the following steps: mixing ethyl lactate, ethyl 3-chloropropionate and ethanol, and reacting under the conditions of metal sodium and heating reflux; after the reaction is finished, distilling off the ethanol under reduced pressure, neutralizing the residual reaction liquid with dilute sulphuric acid, extracting with an organic solvent, separating the liquid to obtain an organic phase, and concentrating the organic phase under reduced pressure to obtain a 2-methyl-4-methyl ester tetrahydrofuran-3-ketone crude product; the method comprises the following steps: heating a 2-methyl-4-methyl ester tetrahydrofuran-3-ketone crude product under the catalysis of cationic resin to hydrolyze, filtering out the cationic resin, extracting with an organic solvent, separating liquid to obtain an organic phase, concentrating under reduced pressure, and rectifying to obtain breadone. According to the method for synthesizing breadone, use of a large amount of acid water is avoided, output of a large amount of waste acid is avoided, the process is more environmentally friendly, meanwhile, the yield is high, the steps are simple, and the industrial production prospect is wide.

The application discloses a green process for synthesizing 4-methyl-2H-pyrane-2,6(3H)-dione, which comprises the following steps: (a) hydrolyzing 4,6-dimethyl-2-oxo-2H-pyrane-5-ethyl formate with liquid alkali to obtain a hydrolysis mixture, and performing negative pressure distillation on the hydrolysis mixture to recover an ethanol aqueous solution; (b) neutralizing the product of the negative pressure distillation to 7.0-7.5, centrifuging to obtain a filtrate and a residue, drying the residue to obtain anhydrous sodium salt, and performing three-stage extraction on the filtrate to obtain an aqueous phase and an organic phase; (c) performing cooling crystallization on the aqueous phase, centrifuging to obtain a precipitate and a first centrifugal filtrate, wherein the first centrifugal filtrate is used for preparing liquid alkali; performing concentration crystallization on the organic phase, recovering an extraction agent, cooling to crystallize when the concentration crystallization is performed to the point that crystals are precipitated, and centrifuging to obtain 3-methyl pentene diacid solid and a second centrifugal filtrate, wherein the second centrifugal filtrate is used for concentration crystallization; and (d) performing ring formation on the 3-methyl pentene diacid by dehydration reaction with a dehydrating agent, wherein the dehydrating agent is acetic anhydride or acetyl chloride. In this way, the discharge amount of pollutants is greatly reduced.

The invention provides a piperidone synthesis tail gas treatment method, which comprises: (1) carrying out first condensation on piperidone synthesis tail gas to obtain a first condensate and a first non-condensable gas; performing second condensation on the first non-condensable gas to obtain second condensate and second non-condensable gas; recovering the first condensate and the second condensate with acetone to obtain an acetone product; (2) the second non-condensable gas is subjected to acid pickling absorption, and an absorption rich solution and absorption tail gas are obtained; crystallizing the absorption rich solution to obtain an ammonium salt product; and (3) sequentially carrying out water washing, third condensation and adsorption on the absorption tail gas to obtain purified gas. The method provided by the invention can realize recovery of acetone and resource utilization of ammonium sulfate by-products, and has a wide application prospect.

The invention relates to the technical field of medical intermediates, and provides a synthesis method of 7-bromo-8-fluoro-6-(trifluoromethyl) quinazoline-2, 4 (1H, 3H)-diketone, which comprises the following steps: S1, by taking 2-fluoro-4-trifluoromethyl benzoic acid as a raw material, adding Br2 under the conditions of a lithium reagent and diisopropylamine, and reacting to obtain a compound A; s2, adding tert-butyl alcohol, triethylamine and diphenyl azide phosphate into the compound A, and reacting to obtain a compound B; s3, the compound B and N-iodosuccinimide are subjected to a heating reaction, and a compound C is obtained; s4, adding the compound C into dimethylformamide, adding CuCN, and reacting to obtain a compound D; and S5, reacting the compound D with urea to obtain the product. Through the technical scheme, the problems of long synthetic route and low yield of the 7-bromine-8-fluoro-6-(trifluoromethyl) quinazoline-2, 4 (1H, 3H)-diketone in related technologies are solved.

The utility model provides a kind of for ringazine ketone synthesis automatic mixing device, belong to ringazine ketone synthesis technical field, including mounting plate, mixing box and mounting frame, the top of mounting plate is fixedly installed with mounting sleeve, the inside sliding installation of mounting sleeve has sliding rod, the top of sliding rod is fixedly installed with first motor.The utility model can make gear rotate by the rotating action of second motor output end, meshing between gear and rack is utilized, so that sliding rod can slide along the inside of mounting plate, so that rotating shaft can be in the process of descending can make protective cover and the top of mounting plate adhere to each other, while rotating shaft moves up and down in the process, can drive stirring vane moves up and down in the inside of mounting plate, can be more uniform in the process of mixing, so that buffer sleeve and mixing box adhere to each other limit, buffer sleeve and the outside of mixing box can be closely adhered to each other by spring.

The invention provides a method for synthesizing an olefin furan compound by catalyzing eneyne ketone through rhodium metal. The synthesis method of the alkenyl furan comprises the following step: reacting an eneyne ketone compound with alkenyl azide under the catalysis of cheap metal rhodium to generate the alkenyl furan compound. The synthesis method is simple and rapid, mild in condition, neutral in reaction condition, free of hidden danger of equipment corrosion, and capable of reacting under air condition without inert gas protection. Therefore, the method has potential industrial application value. # imgabs0 #

The present invention discloses a short-chain dehydrogenase mutant and its application in catalyzing the synthesis of symmetrical chiral diols from symmetrical diketones. The short-chain dehydrogenase mutant is obtained by single or multiple mutations at positions 94, 145, 153, 188, 196, or 208 of the amino acid sequence of the short-chain dehydrogenase shown in SEQ ID NO.2. The short-chain dehydrogenase mutant of the present invention can convert potential chiral diketones at high substrate concentrations into corresponding chiral diols with high stereoselectivity, solving the problems of low yield, low substrate loading, and low product optical purity in existing methods. The present invention uses pure isopropanol as a cosolvent, effectively preventing problems such as subsequent extraction and emulsification, facilitating the extraction and separation of subsequent products; using wet bacteria as a catalyst, the reaction cycle can be achieved without the addition of additional coenzymes, simplifying production operations and reducing production costs, in line with the concept of green chemistry.

The utility model relates to the technical field of material filling, and discloses a feeding device for synthesis of methyl isobutyl ketone, which comprises a tank body, a cleaning mechanism, a feeding pipe, a discharging port, a feeding pipe, a feeding pipe, a discharging port, a feeding mechanism, a feeding mechanism, a discharging mechanism and a discharging mechanism, and is characterized in that the top of the tank body is fixedly connected with a top plate, and the top of the top plate is fixedly connected with the feeding pipe; the cleaning mechanism comprises a servo motor fixedly connected to the top of the top plate, the output end of the servo motor is fixedly connected with a transmission rod, and a scraper is arranged outside the transmission rod. The adjusting mechanism comprises an adjusting shell fixedly connected to the outer portion of the discharging port, the worm is driven by the rotating disc to rotate, so that the worm gear is driven to rotate, finally the adjusting plate is made to rotate, materials are smoothly discharged through linkage operation of a series of structures, and the discharging efficiency is improved. The feeding amount during synthesis of methyl isobutyl ketone can be accurately controlled, it is ensured that the synthesis reaction is carried out according to expectation, and the accuracy and stability of the synthesis reaction are improved.

The invention belongs to the field of molecular biology and enzyme engineering, and discloses an amine dehydrogenase mutant and application thereof in chiral beta-aminoketone synthesis. The amine dehydrogenase mutant provided by the invention can catalyze reductive amination of various 1, 3-diketone substrates, the substrate spectrum of the mutant is greatly broadened, the activity of the amine dehydrogenase in catalytic synthesis of chiral beta-aminoketone is remarkably improved, the problems of low activity, poor regioselectivity, narrow catalytic substrate range and the like of the amine dehydrogenase are solved, and the application prospect is broad. Wide application prospects are realized.

The invention relates to a hemsleya amabilis cytochrome oxidase HcCYP89A140 gene and application thereof, and belongs to the technical field of biology. The nucleotide sequence of the hemsleya amabilis cytochrome oxidase HcCYP89A140 gene is as shown in SEQ ID NO. 1. The preparation method comprises the following steps: by taking 11-Carbonyl-ucurbita-5, 24-diene-3beta, 16 alpha, 20, 23-tetrol as a substrate, carrying out condensation dehydration furanation on a hydroxyl group at a C20 site and a hydroxyl group at a C24 site under the catalysis of HcCYP89A140, and then carrying out ketonylation on a C3 site under the catalysis of SDR34, so as to generate the 16 alpha, 23-Dihydroxy-gratiogenin-3-one. According to the invention, heterologous synthesis of 16, 23 dihydroxylated glanolin is realized, and the method is of great significance to a cucurbitacine compound biosynthesis mechanism, derivative compounds thereof and efficient heterologous synthesis of the cucurbitacine compounds.

The invention belongs to the field of organic synthesis and catalysis, and particularly relates to a method for synthesizing damascenone B. According to the method, narrow-pore sulfonic acid type polystyrene-divinylbenzene supported acid resin A1-M1 is adopted as a catalyst, beta-ionone isomerization rearrangement is catalyzed in a mixed solvent of ethyl alcohol and 2-methyltetrahydrofuran, the content of water in a reaction system is accurately controlled to be 0.01-0.10 wt%, generated water is continuously removed, and the content of the water in the reaction system is accurately controlled to be 0.01-0.10 wt% in combination with the narrow-pore confinement effect of the catalyst, so that beta-ionone isomerization rearrangement is achieved. The high-selectivity synthesis of the damascenone B is realized. The organic purity of the product is 99.2-99.9 wt%, the isomer selectivity is 97.0-99.5 wt%, the residual solvent is less than or equal to 1000mg / kg, and the heavy metal content meets the essence raw material standard. The problems that in the prior art, mechanical stability and multi-cycle usability of a catalyst are difficult to consider, extremely low water content control and catalytic activity are kept contradictory, deep purification of products and mild operation conditions conflict and the like are solved, and the industrial application value of flavors and fragrances is wide.

The invention provides a method for biosynthesizing acrylic acid from methanol. The method comprises the following steps: introducing carbon-compound methanol into an acrylic acid synthesis route, catalyzing methanol and oxygen to generate formaldehyde through methanol oxidase, and catalyzing formaldehyde condensation into 1, 3-dihydroxyacetone through artificial formaldehyde condensation enzyme; 1, 3-dihydroxy acetone is catalyzed by dihydroxy acetone kinase to be subjected to phosphorylation to generate dihydroxy acetone phosphate, and the dihydroxy acetone phosphate is catalyzed by CEAS to synthesize acrylic acid. According to the invention, 10 kinds of CEAS from different sources are also excavated, and 3-phosphoglyceraldehyde or phosphoric acid-1, 3-dihydroxy acetone can be catalyzed to be converted into acrylic acid. By utilizing the enzyme with the highest activity, cheap methanol can be converted into acrylic acid only through four steps of enzymatic cascade reaction, thermodynamics is beneficial, and high-yield and high-yield acrylic acid can be obtained without a strict environment.

The invention discloses an aurone compound and a preparation method thereof. The method adopts a one-pot reaction, is a green aurone synthesis method taking water as a solvent, benzaldehyde with different substituent groups and substituted benzofuranone are taken as raw materials, toluene is dropwise added into the water solvent, aldol reaction is realized under a reflux condition, and a target product is obtained at a good yield. According to the method, water is used as an environment-friendly solvent, reactants are promoted to form a stable transition-state compound through hydrogen-bond interaction, and the stereoselectivity of the reaction is remarkably improved. The reaction conditions are mild, the use of highly toxic reagents, dangerous strong acids, strong alkalis and highly flammable reagents is avoided, and the method has higher environmental protection property and safety. In addition, protection group operation is not needed in the reaction process, the steps are simplified, and the atom economy is improved.

The application discloses a watermelon ketone synthesis production process organic waste gas treatment device, belongs to the field of waste gas treatment. The watermelon ketone synthesis production process organic waste gas treatment device, including main body cylinder, air inlet bin and air outlet bin, the side of air inlet bin is equipped with waste gas treatment main part, the side of air inlet bin is equipped with cleaning brush frame driven by linear motor, the inside of main body cylinder is equipped with fixed plate. The watermelon ketone synthesis production process organic waste gas treatment device, start suction fan and cleaning brush frame, the suction fan in rotating state can drive the sleeve transmission connection fast rotation, cooperate with moving block one, spring one, arc plate, torsional spring block one, rotating rod one, rotating rod two, moving rod one, spring two and stress plate, so that the cleaning brush frame is moved and receives additional force, so as to improve the friction between the cleaning brush frame and the waste gas treatment main part, improve the cleaning effect of the cleaning brush frame.