27results about How to "Efficient Catalysis" patented technology

The invention provides a bimetallic-catalyzed magnesium-based hydrogen storage material and a preparation method thereof, and relates to the technical field of hydrogen energy. The magnesium-based hydrogen storage material is a compound mainly formed by magnesium hydride and a catalyst, and the catalyst is a bimetallic catalyst TiO2 / C / Ni formed by loading nickel and titanium dioxide on a carbon substrate; according to the magnesium-based hydrogen storage material MgH2-TiO2 / C / Ni, a bimetallic catalyst TiO2 / C / Ni is introduced into MgH2, trace efficient catalysis of MgH2 is achieved, the hydrogen storage capacity of MgH2 is not excessively lost, meanwhile, the excellent catalytic effect can be achieved, and therefore the prepared magnesium-based hydrogen storage material MgH2-TiO2 / C / Ni shows excellent hydrogen storage performance and hydrogen absorption and desorption cycle stability. The invention also provides a preparation method of the bimetal catalyzed magnesium-based hydrogen storage material, and the preparation method introduces a catalyst into an MgH2 system through a ball milling method to realize stable preparation of the magnesium-based hydrogen storage material.

The invention relates to a high-yield trans-aconitic acid engineering bacterium as well as a construction method and application thereof, and belongs to the technical field of gene engineering. In the scheme of the invention, the inventor introduces mitochondrial localization signal peptide to be combined with the aconitic acid isomerase to form a gene element, and an expression cassette containing the gene element is introduced into the strain by adopting a genetic engineering technical means, so that the aconitic acid isomerase expressed in the constructed recombinant strain can be localized into mitochondria, and the expression efficiency of the recombinant strain is improved. Metabolic pathways related to trans-aconitic acid synthesis are located in the same zone, so that the capacity of fermenting and producing trans-aconitic acid by the recombinant strain is improved. The technical scheme disclosed by the invention not only has a good application prospect and production economic value, but also provides a referential new thought for transformation of strains related to other fermentation processes.

The application belongs to the field of medical materials, and particularly relates to a metal core enhanced double-barrier piezoelectric nano system and a preparation method and application thereof. The preparation method comprises the following steps: first, a core-shell structure of'metal@mesoporous titanium dioxide@mesoporous barium titanate' is prepared through a step-by-step reaction, and then the target nanoparticles are obtained through lipid wrapping. The system innovatively constructs a double-barrier structure, can self-trigger active oxygen under a physiological pressure of 4 mmHg, realizes endogenous pressure self-driven treatment of malignant ascites, has the advantages of low pressure, high catalytic efficiency, long-term structural stability and good biocompatibility, solves the problems that existing treatment methods are highly invasive and depend on exogenous stimulation, and provides a new safe and efficient technical scheme for the treatment of malignant ascites.

The invention discloses chiral gold nanoparticles for an alkaline electrolysis water oxygen evolution reaction catalyst and a synthesis method and application thereof, L-shaped gold nanoparticle branched particles and D-shaped gold nanoparticle branched particles of chiral multi-branched gold nanoparticles are synthesized, and the chiral multi-branched gold nanoparticles are further used for catalyzing an oxygen evolution reaction. In the synthesis process, the chiral strength of a sample can be regulated and controlled by regulating and controlling the concentration of the chiral ligand, and the chiral strength can be reflected through the signal strength of circular dichroism. Compared with the prior art, the preparation method is simple, the manufacturing cost is low, and the catalytic performance of the oxygen evolution reaction is excellent. The oxygen evolution reaction performance of the L-shaped gold nanoparticle branch type particles in the sample is far superior to that of D-shaped gold nanoparticle branch type particles. Under the current density of 10 milliamperes per square centimeter, the L-shaped gold nanoparticle branch type particles reach 355.1 millivolts and 449.7 millivolts, the Tafel slope reaches 61.72 millivolts per ten degrees, the stability can be kept for 24 hours under the current density of 10 milliamperes per square centimeter, and the stability is good.

The invention discloses a cerium-based photosensitizer, a preparation method and application of the cerium-based photosensitizer in photocatalytic reaction, and relates to the technical field of coordination chemistry and photocatalysis. The general formula of the cerium-based photosensitizer is Ce (L1) 3 (L2) m, and L1 comprises a strong field anion ligand of at least one strong electron withdrawing group or a strong field anion ligand of a rigid structure; l2 is a neutral nitrogen-containing heterocyclic ligand, and m is 0 or 1. According to the invention, strong visible light absorption and long excited state life can be achieved by introducing L1, and the Ce < + > / Ce < 4 + > oxidation potential can be reduced to a mild range, so that the Ce < 4 + > intermediate can be efficiently reduced by a mild reducing agent generated in the reaction, and simple catalytic circulation without an external reinforced reducing agent is realized. When being applied to boronation reaction of various alkenyl / aryl / heteroaryl halides and various organic boron reagents, the photosensitizer shows high catalytic activity (the yield is as high as 91%), the performance is superior to that of a noble metal photosensitizer, but the cost is remarkably reduced, and the photosensitizer is environment-friendly.

The invention discloses a preparation method for promoting cis-isomerization of lycopene, which comprises the following steps: catalyzing the lycopene by using a bimetallic organic framework material as a catalyst to realize cis-isomerization, catalyzing the lycopene by using the catalyst to realize cis-isomerization of the lycopene, and catalyzing the lycopene by using the catalyst in an electron-rich environment to realize cis-isomerization of the lycopene. Conjugated double bonds of all-trans-lycopene are more easily attacked and activated, so that the conjugated double bonds are rotated into corresponding configurations, and the method is green and efficient and has great application prospects.

This invention provides an application of a catalyst combination in the preparation of N-alkylcarbazole, comprising: using N-alkylaniline and 1,2-cyclohexanediol as reactants, reacting first in the presence of a first catalyst, removing the first catalyst after the reaction, and then adding a second catalyst to react again to obtain the target product; the first catalyst is a ruthenium-based catalyst, which consists of a support and an active component, wherein the support is a nitrogen-doped amorphous mesoporous carbon material, and the active component is metallic ruthenium; the second catalyst is a palladium-based catalyst. In the raw material system for synthesizing N-alkylcarbazole, this invention first adds a ruthenium-based catalyst to react, then removes the ruthenium-based catalyst before adding the palladium-based catalyst. Through this two-step combination, the need for additives such as acids and bases in the synthesis is eliminated, and efficient catalysis is achieved at a lower reaction temperature. This not only significantly improves the yield of N-alkylcarbazole but also exhibits high catalyst recovery activity.

Provided are a transketolase mutant, and an encoding gene and the use thereof, relating to the technical field of enzyme engineering. The transketolase mutant provided in the present invention has a sequence as set forth in SEQ ID NO:16 with an amino acid mutation. Provided are a high-stereoselectivity R transketolase mutant with an amino acid sequence of SEQ ID NO:1, a recombinant expression vector containing the encoding gene, a host cell containing the recombinant expression vector, a method for preparing the high-stereoselectivity R transketolase mutant, the use of the R transketolase mutant in catalyzing aromatic aldehyde to form high-stereoselectivity R-aromatic dihydroxyketone, and the use of the encoding gene in catalyzing aromatic aldehyde to form high-stereoselectivity R-aromatic dihydroxyketone. The stereoselectivity of p-methylsulfonephenyl dihydroxyketone produced under the catalysis of the mutant EcTK1_YYH is 95.2% ee (R), and a high activity and high steroselectivity are achieved.

The invention discloses a method for preparing cyclohexanone oxime by catalyzing cyclohexanone through a molecular sieve catalyst TS-1, and belongs to the technical field of organic synthesis. According to the method, cyclohexanone, an ammonia source, hydrogen peroxide, a reaction solvent and a molecular sieve catalyst TS-1 are added into a reactor, the molar ratio of ammonia to cyclohexanone is (1.60-3.10): 1, the molar ratio of hydrogen peroxide to cyclohexanone is controlled to be (1.0-1.8): 1, the mass concentration of the molecular sieve catalyst TS-1 is 0.5-5%, the reaction temperature is controlled to be 35-80 DEG C, stirring reaction is carried out for 0.5-6 h, after the reaction is finished, a reaction product is subjected to post-treatment, and the product is obtained. And filtering, distilling and separating to obtain cyclohexanone-oxime. On the premise of innovative application of a molecular sieve catalyst, optimization of reaction conditions and simple, green and environment-friendly separation method, the invention provides a method for preparing cyclohexanone-oxime under mild and well-controlled reaction conditions, and the conversion rate of raw materials and the selectivity of products are effectively improved.

The application relates to the technical field of high ignition point insulating oil, and particularly discloses a metal-supported catalyst and application of the metal-supported catalyst in high ignition point insulating oil. The metal-supported catalyst comprises a carrier, an active metal supported on the carrier and a composite metal oxide mesoporous layer, the carrier is a metal oxide and is at least one selected from MoO2, Al2O3, ZrO2, MgO, TiO2 and SnO2; the active metal is a transition metal and is at least one selected from Fe, Co, Cu, Ni, Ti, Zr, Mn, V and Zn; and raw materials of the composite metal oxide mesoporous layer comprise SiO2, ZrO2 and a carbon precursor. The metal-supported catalyst can be used for synthesizing ester insulating oil, can produce high-efficiency catalysis on synthesis of the ester insulating oil with a small amount, has high cycle stability and can keep excellent catalytic efficiency after multiple cycles.

The invention discloses a method for preparing a gallium-doped hollow ZSM-5 molecular sieve through microwaves and application of the gallium-doped hollow ZSM-5 molecular sieve, and relates to the technical field of molecular sieve catalyst preparation. The preparation method comprises the following steps: mixing a silicon source, a template agent and deionized water, stirring to prepare a precursor, transferring the precursor into a digestion tank, carrying out microwave hydrothermal treatment, and roasting in a muffle furnace to remove the template agent to obtain a pure silicon molecular sieve; the method comprises the following steps: taking a pure silicon molecular sieve, adding an aluminum source, a template agent and deionized water, carrying out ultrasonic treatment, transferring into a digestion tank, carrying out microwave hydrothermal and dissolution-recrystallization, and roasting the obtained product in a muffle furnace to remove the template agent so as to obtain a hollow ZSM-5 molecular sieve; the method comprises the following steps: taking a hollow ZSM-5 molecular sieve, adding gallium nitrate and deionized water, carrying out ultrasonic treatment, transferring into a digestion tank, and carrying out gallium doping under microwave irradiation; and putting the dried product into a tubular furnace, and carrying out heat preservation in an argon atmosphere at 200-300 DEG C to obtain the gallium-doped hollow ZSM-5 molecular sieve. The microwave hydrothermal process and the dissolution-recrystallization process are combined, so that the preparation time of the hollow ZSM-5 molecular sieve is effectively shortened, and the energy consumption is reduced.

This invention discloses a catalytic synthesis method for 1-arylmethyl-4-arylmethyl-3-hydroxypyrrole-2-( 5H A method for reacting 1-arylmethyl-4-arylmethylenepyrrole-2,3-dione compounds and diethyl phosphonate in an organic solvent under the presence of a base catalyst undergoes a Michael addition and a 1,4-P-Brook rearrangement tandem reaction. Sodium ethoxide is then added for hydrolysis to yield 1-arylmethyl-4-arylmethyl-3-hydroxypyrrole-2,3-dione compounds and their derivatives. 5H )-ketone. This invention achieves 3-hydroxypyrrole-2-( )-ketone in one step through a series of reactions in a one-pot reaction mode. 5H Alkylation of ketones at the C(4) position: The catalyst used is mild and readily available, enabling highly efficient catalytic reactions with good yields of the target product. It is both economical and environmentally friendly, making it suitable for large-scale applications.

The invention discloses a chemical synthesis method of a type b haemophilus influenzae capsular polysaccharide derivative, and belongs to the field of carbohydrate chemistry. The invention provides a modular synthesis strategy based on a phosphoramidite method. According to the strategy, a dimer receptor with a connecting arm at the O3 site of ribose at a non-reducing end is used as a main starting compound, and a phosphoramidite monomer donor and a dimer donor are respectively used as extension units of an odd-numbered polymer synthesis route and an even-numbered polymer synthesis route. Through optimization of a coupling catalysis strategy and optimization of a protecting group removal method, chemical synthesis of 1-12 repetitive units is efficiently completed. According to the synthesis method, the raw materials are cheap and easy to obtain, the preparation method is simple and easy to repeat, the yield of each step is relatively good, and the method has a very good application prospect in vaccine development of the haemophilus influenzae type b.

The application discloses a specific beta-glucosidase for preparing CK and application thereof, and belongs to the technical field of biological catalysis and natural product bioconversion. The amino acid sequence of the specific beta-glucosidase is shown as SEQ ID NO:1. The enzyme can efficiently catalyze ginsenoside Rb1 to generate rare ginsenoside Compound K (CK) through a step-by-step deglucosylation reaction. The specific beta-glucosidase is coupled with a product in-situ separation technology, CK generated in the reaction process is removed in real time or intermittently through an adsorption resin, membrane separation or extraction and the like, accumulation of the product in the reaction system is reduced, and therefore, the substrate conversion efficiency and the product yield are significantly improved, and the molar conversion rate can reach more than 90%. The application can realize continuous or semi-continuous operation, effectively simplifies a subsequent separation and purification process, reduces production cost, and has a wide application prospect in the fields of medicines, functional foods and cosmetics and the like.

The invention discloses a preparation method of a magnetic cottonseed protein nanosphere with high lipase loading capacity, and relates to the technical field of enzyme engineering and lipase loading in the biological industry, and the preparation method comprises the following steps: coating nano Fe3O4 particles by using plant polyphenol and cottonseed protein by using an anti-solvent method to obtain the magnetic cottonseed protein nanosphere; adding the magnetic nano-protein spheres into a lipase solution, loading lipase on the magnetic cottonseed protein nano-spheres by utilizing covalence and secondary action between plant polyphenol and cottonseed protein, and separating, washing and drying to obtain the magnetic cottonseed protein nano-spheres with high lipase loading capacity. According to the preparation method, the magnetic cottonseed protein nanospheres are prepared by coating Fe3O4 nanoparticles with an anti-solvent method, lipase is immobilized on the surfaces of the nanospheres through covalence and secondary action between plant polyphenol and protein, parameters are optimized, and the magnetic cottonseed protein nanospheres with high lipase loading capacity are obtained. The magnetic cottonseed protein nanospheres obtained by the invention can realize efficient catalysis and cyclic utilization of lipase.

The present application provides a metallocene compound, and a preparation method and application thereof. The metallocene compound of the present application includes a structure as shown in Formula a, where Ar is selected from a substituted or unsubstituted C6-C30 aryl; Cp' is selected from a substituted or unsubstituted cyclopentadienyl, indenyl, or fluorenyl; X is at least one of halogen, substituted or unsubstituted C1-C30 alkyl, alkoxy, substituted or unsubstituted C2-C30 dialkylamino, alkenyl, or substituted or unsubstituted C6-C30 aryl; and M is a transition metal element. The metallocene compound is suitable for catalyzing a C6-C30 long straight chain α-olefin raw material and also a mixed long branched chain non-terminal olefin raw material, and may obtain a polymerization product with a target molecular weight according to demand.

The invention discloses a beta-lactamase immobilized sponge and a preparation method and application thereof, and belongs to the technical field of environmental engineering.Polydopamine coated melamine sponge is used as a carrier, beta-lactamase cross-linked enzyme aggregate is immobilized on the surface of the carrier through a cross-linking method, and the beta-lactamase immobilized sponge is prepared. The beta-lactamase immobilized sponge (MS (at) beta-lactamase-CLEAs) is obtained, so that the antibiotics in the wastewater can be efficiently removed. By adopting the method disclosed by the invention, the stability and the catalytic activity of the beta-lactamase are enhanced, and the MS-coated beta-lactamase-CLEAs disclosed by the invention can be used for quickly and efficiently hydrolyzing beta-lactam antibiotics in wastewater and remarkably reducing the concentration of the beta-lactam antibiotics; compared with a traditional treatment method, the method has higher treatment efficiency and good reusability, a feasible solution is provided for treatment of wastewater polluted by antibiotics, and the method has wide application prospects.

The invention belongs to the field of gene engineering and enzyme engineering, and particularly relates to an activity-improved UDP glycosyl transferase mutant and application thereof. The glycosyl transferase mutant is a four-combination mutant N2HN1I, and the amino acid sequence of the glycosyl transferase mutant is as shown in SEQ ID NO. 4. The mutant provided by the invention has higher catalytic activity, the conversion rate of a substrate crocetin is high, and the mutant has important industrial application value.

The utility model discloses a novel self-adhesive book wrapping film which comprises a cover protection film, a bottom paper protection film and a side protection film, and a first stainless steel positioning piece is fixedly arranged on the inner wall face of the side protection film. A photocatalytic layer, a first activated carbon adsorption layer and a first positioning layer are sequentially arranged in a first storage groove in the lower surface of the cover protection film from top to bottom, first adhesive layers are arranged on the lower surfaces of the first positioning layer and the cover protection film, and a plurality of first ventilation through holes are formed in the lower surfaces of the first adhesive layers; the first positioning layer is provided with a second breathable through hole, and the upper surface of the cover protection film is provided with a plurality of third breathable through holes; a second activated carbon adsorption layer and a second positioning layer are sequentially arranged in a second storage groove in the upper surface of the backing paper protective film from bottom to top; and second adhesive layers are arranged on the upper surface of the second positioning layer and the upper surface of the backing paper protective film. According to the technical scheme, the textbook protecting device is reasonable in structural design, not prone to damage, good in textbook protecting effect, good in peculiar smell removing effect and good in practicability.

The application discloses a method and device for catalytic leaching of argillaceous uranium ore based on ozone, and relates to the technical field of uranium leaching and reaction equipment. The application utilizes biomass raw materials and iron-based material powder to prepare a magnetic composite material with catalysis-adsorption dual functions through in-situ reduction by high-temperature heat treatment. The slurry of argillaceous uranium ore and the magnetic composite material are mixed in a reactor for reaction. Ozone is introduced through an aeration disc to avoid bubble aggregation, significantly increase the gas-liquid contact area, and improve the ozone utilization rate. A spiral guide plate is arranged in the reactor to effectively prolong the gas-liquid contact time and improve the ozone mass transfer efficiency. A magnetic recovery device is used to recover the magnetic material to ensure the catalyst activity, reduce the catalyst loss rate, and realize efficient catalysis. Through optimization of the reactor structure, the catalyst preparation process and the process flow, the ozone utilization rate and the leaching efficiency of the argillaceous uranium ore are significantly improved, and the catalyst recycling and the recycling of residual gas are realized.

This invention relates to the field of chemical synthesis, and more particularly to a process for producing allyl diethylene glycol dicarbonate, comprising the following steps: using allyl alcohol and dimethyl carbonate as raw materials, a transesterification reaction is carried out under the action of a core-shell catalyst to produce dipropylene carbonate; after solid-liquid separation and vacuum distillation to recover methanol and dimethyl carbonate, a second transesterification reaction is carried out with diethylene glycol under the same catalyst to produce allyl diethylene glycol dicarbonate; finally, high-purity product is obtained by multi-stage vacuum distillation purification. The core-shell catalyst uses MCM-41 molecular sieve as a support, with an amino-modified and zirconium-ion-coordinated core, encapsulated by an interface layer and a phenyl-modified silica shell, exhibiting high activity, high selectivity, and excellent structural stability. This process is mild, the catalyst is recyclable, and the product yield is high with excellent purity, making it suitable for industrial production.

The invention relates to the technical field of industrial safety, and discloses a special gas double-sleeve conveying leakage detection device which comprises a detection mechanism, the detection mechanism comprises an outer pipe, and a gas suction unit is arranged at the bottom end of the outer pipe. According to the leakage detection device for special gas double-sleeve conveying, a first supporting frame is tightly connected with a first mounting block through a bolt, an outer pipe is fixed to the inner wall of the first supporting frame, then a first motor drives a lead screw to rotate at a constant speed, a gas suction shell can smoothly slide on the surface of the first supporting frame under the cooperation of the lead screw and a sliding rail, and a gas suction groove which is elaborately formed is formed in the bottom end of the gas suction shell; a second motor is fixed in a groove through a first mounting frame, when the second motor is started, first fan blades are driven to rapidly rotate, air suction of a lower area is achieved, an air suction shell can orderly suck air along an outer pipe through accurate control of a first motor, and when special gas leaks and especially has harmfulness, the device can rapidly suck air, the safety of the detection device is remarkably improved, and the detection efficiency is improved. And a reliable guarantee is provided for smooth proceeding of related work.

This invention relates to the field of functional polymer materials and discloses a method for preparing an antibacterial composite nanofiber material with cascade activity. The method includes: dissolving a gold precursor in a solvent; adding a polymer to obtain a polymer solution; reacting with a sodium borohydride solution; electrospinning to obtain an Au composite nanofiber membrane; dissolving TCPP in a mixed solvent of N-N-dimethylformamide / ethanol; adding Cu₂O, polyvinylpyrrolidone, and trifluoroacetic acid; reacting to obtain Cu-TCPP; adding the Cu-TCPP dispersion to the surface of the Au composite nanofiber membrane under vacuum filtration; and drying. In the antibacterial composite nanofiber material of this invention, Cu-TCPP is stably anchored on the surface of the nanofiber membrane, preventing excessive encapsulation of Cu-TCPP and thus reducing the therapeutic effect. In a weakly alkaline environment conducive to infection, this antibacterial composite nanofiber material can utilize Au nanozymes as initial enzymes to continuously catalyze the production of gluconic acid and H₂O₂ from glucose, thereby activating the POD-Like activity of Cu-TCPP to catalyze the generation of hydroxyl radicals to kill bacteria.

The utility model relates to the technical field of plasma thermocatalysis, and discloses a miniature plasma thermocatalysis reaction device which comprises a base, a catalysis mechanism is arranged at the top of the base and comprises a thermocatalysis reactor, the thermocatalysis reactor is arranged at the top of the base, and the thermocatalysis reactor is arranged on the base. A heating furnace is fixedly connected to the right side of the thermocatalytic reactor, the right side of the top of the heating furnace communicates with a reactor, and a system pressure gauge is arranged on the left side of the top of the heating furnace. According to the utility model, gas and liquid raw materials enter the reactor through a gas path and a circulating liquid path respectively; a touch screen sets flow pressure; a control button starts a heating furnace for gradient heating and constant temperature; a plasma cathode in a reaction section is combined with a high-frequency power supply to adjust power; the product is analyzed by a chromatograph after being separated, flow is controlled by a valve, and the device is miniature and efficient in catalysis.

This invention discloses a method for preparing a peak-supported carbon nanocatalyst by metal-directed carbonization, comprising: Step 1: preparing hierarchical organic microspheres; mixing at least one aldehyde compound with an aprotic solvent to obtain solution I, mixing at least one amino compound with a protic solvent to obtain solution II, and mixing solution I and solution II to perform a condensation reaction to obtain hierarchical organic microspheres; Step 2: loading metal ions; dispersing the hierarchical organic microspheres prepared in step 1 in a solution containing metal ions, and loading the metal ions onto the hierarchical organic microspheres to obtain a metal ion-organic microsphere composite; Step 3: carbonization; subjecting the metal ion-organic microsphere composite prepared in step 2 to carbonization treatment to obtain a peak-supported carbon nanocatalyst. The catalyst prepared by this invention has the characteristics of highly accessible active sites and structural stability, exhibiting excellent anti-poisoning performance and catalytic activity.

The invention provides a method for catalyzing an alpha, beta, gamma, delta-unsaturated ketone chiral boron addition reaction through a nano-composite microsphere supported copper material, and belongs to the technical field of asymmetric catalyst.The method comprises the following steps that in a reaction solvent, alpha, beta, gamma, delta-unsaturated ketone chiral boron addition reaction is carried out, and alpha, beta, gamma, delta-unsaturated ketone chiral boron addition reaction is carried out; the preparation method comprises the following steps: carrying out chiral boron addition reaction on beta, delta-unsaturated ketone and B2 (pin) 2 under the action of a nano-composite microsphere loaded copper material and a chiral ligand to obtain a 1, 4-chiral boron compound; a carrier of the nano-composite microsphere loaded copper material is a PS-CS-SiO2 nano-composite microsphere, the PS-CS-SiO2 nano-composite microsphere is composed of PS monodisperse microsphere powder, SiO2 and chitosan, and an active component Cu < 2 + > is loaded on the PS-CS-SiO2 nano-composite microsphere. 3-7 mg of the nano composite microsphere loaded copper material is added into every 0.2 mmol of alpha, beta, gamma, delta-unsaturated ketone. The nano-composite microsphere loaded copper material is used as a catalyst to catalyze alpha, beta, gamma, delta-unsaturated ketones to perform chiral boron addition reaction, and the nano-composite microsphere loaded copper material is used as a novel catalytic material, can be recycled, and is green and environment-friendly.

The invention discloses a selective hydrolysis preparation method of PHS (Polyhydroxystyrene) resin for photoresist, which comprises the following steps: by taking poly (p-acetoxystyrene) and a copolymer thereof as raw materials and alcohol, alkyl, ester, ether and the like as solvents, carrying out hydrolysis reaction at the temperature of 30-80 DEG C under the action of a catalyst, thereby preparing the poly (p-acetoxystyrene) and the copolymer thereof, an amino or sulfonic MOFs material is used as a catalyst. And selectively hydrolyzing the poly (p-acetoxystyrene) and the copolymer thereof to prepare the poly (p-hydroxystyrene) and the copolymer resin thereof. The method has the advantages of efficient catalysis, reduction of impurities in a finished product, improvement of product quality, simplification of post-treatment, reduction of cost and selective hydrolysis.