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34 results about "Ion regulation" patented technology

Ionic regulation is the maintenance of the concentrations of the various ions in the body fluids relative to one another. There is no consistent distinction between the two processes; organs that participate in one process at the same time participate in the other.

Metal ion concentration regulation device and method, and etching equipment

The invention discloses a metal ion concentration regulation device and method, and etching equipment. The metal ion concentration regulation device comprises a liquid supply pipeline, a metal ion regulation system, a metal ion detection system and a control circuit. The metal ion regulation system and the metal ion detection system are sequentially in the liquid supply pipeline in the direction of etching liquid flowing through the liquid supply pipeline and both communicate with the liquid supply pipeline. The control circuit is electrically connected with the metal ion regulation system and the metal ion detection system and is used for controlling the metal ion regulation system to regulate the concentration of metal ions in the etching liquid according to the current metal ion concentration, transmitted by the metal ion detection system, of the etching liquid and preset metal ion concentration upper and lower threshold values. Through cooperative operation of all the components, the metal ion concentration regulation device conducts regulation on the concentration of metal ions in the etching process, so that the etching rate tends to be stable, the etching effect is improved, and the probability of short circuiting, disconnection and the like of metal conducting wires is reduced.
Owner:BOE TECH GRP CO LTD

Lithium Ni-Co aluminate positive electrode material co-doped with negative ions and positive ions and preparation method of positive electrode material

The invention is applicable to the technical field of a lithium battery and provides a lithium Ni-Co aluminate positive electrode material co-doped with negative ions and positive ions and a preparation method of the positive electrode material. The method comprises the steps of firstly, pre-sintering a lithium Ni-Co aluminate NCA precursor to form a porous honeycomb quasi-spherical pre-sintered precursor by employing a pre-sintering method of spraying a sodium bicarbonate solution and an F solution; secondly, preparing a solution from a Mg source and Nb source according to a proportion, mixing with the pre-sintered precursor under a water system, and effectively guiding a Mg and Nb solution into a positive electrode material substrate through honeycomb holes; thirdly, spraying an F ion regulation agent solution during material mixing and lithium supplement by a high mixing machine so that materials are fully and uniformly mixed; and finally, performing high-temperature sintering to make a finished product crystallized so as to obtain the lithium Ni-Co aluminate positive electrode material co-doped with the negative ions and the positive ions. In the positive electrode material, positive ion mixing can be reduced by Nb<4+>, polarization can be reduced by Mg<3+>, the electrochemical performance is improved, no electrochemical reaction of Mg<3+> / Nb<4+> is generated during the charging process, no valence-state change is generated, and an effect of stabilizing a crystal structure can be achieved; and moreover, oxygen can be fixed by F negative ion doping, oxygen precipitationis reduced, the material structure is stabilized, and the cycle property is improved.
Owner:GEM (HUBEI) NEW ENERGY MATERIALS CO LTD

Preparation method and application of miniature pH sensor

The invention relates to a preparation method and application of a miniature pH sensor, and particularly provides a sensing electrode. The sensing electrode comprises: a glass capillary tube with openings at two ends; and an electrochemical probe, wherein the electrochemical probe is modified on the inner wall of the opening in one end of the glass capillary tube, and the diameter of an opening atone end of the glass capillary tube modified with the electrochemical probe is 8-12 microns. The sensing electrode can realize ion regulation and control in a micron pore passage, further realizes high-sensitivity detection of a to-be-detected substance (such as hydrogen ions), has good robustness, and can be combined with various electrochemical instruments for use, so that the sensing electrodeis used for on-line analysis and detection in complex environments such as environments, physiology, pathology or cells.
Owner:INST OF CHEM CHINESE ACAD OF SCI

Preparation technology of lactic acid bacteria beverage

The invention relates to a lactic acid bacterium suspension beverage. The lactic acid bacterium suspension beverage is prepared from the following raw materials in parts by weight: 35-40 parts of a dairy product, 7-10 parts of cane sugar, 0.5-0.8 part of a stabilizing agent, 0.1 part of citric acid / L- lactic acid, 0.03 part of sodium citrate, 0.1-0.5 part of fruit particles, and 5-10 parts of fruit juice. The lactic acid bacterium suspension beverage disclosed by the invention is suitable for the situation that suspended fruit particles are added to a sterilized lactic acid bacteria beverage of which the pH value is 3.8-4.2, and the fruit particles can be uniformly suspended, wherein the stabilizing agent is a compound protective stabilizing agent and stabilizes lactoprotein through charge protection and ion regulation, so that whey is prevented from being separated out and layered, and besides, products are fine and smooth in mouth feel of tissue, are smooth, and are mellow and smooth in special flavor .
Owner:TIANJIN HENGAN FOOD

Reconstituted tobacco chlorine ion regulation and control method

The invention provides a reconstituted tobacco chlorine ion regulation and control method. The method includes the steps that suspended solids in extracting solution generated in an extraction section in the reconstituted tobacco production process are removed through separation and purification; ion exchange is conducted on 10-100% of the total mass of the purified extracting solution through an anion exchanger, and then chlorine ions in the solution are removed; the anion exchanger is used for regeneration through vinyl benzene anion resin and sodium hydroxide; the pH value of the extracting solution after ion exchange is adjusted to be in the range from 5.5 to 8 through malic acid, the extracting solution after ion exchange is mixed with the 0-90% of the extracting solution before ion exchange according to the 10-100% mass, coating production is conducted after the mixed solution is concentrated and mixed, the reconstituted tobacco product coating weight is counted according to product oven dry amount and controlled to be 40%, and then the chlorine ion content of reconstituted tobacco is regulated and controlled within the range from 0.1% to 0.8% by mass. According to the reconstituted tobacco chlorine ion regulation and control method, the problems that the chlorine ion content of the reconstituted tobacco is high and difficult to control can be solved.
Owner:CHINA TOBACCO YUNNAN REMFG TOBACCO CO LTD

Method for demulsifying oil-containing emulsified wastewater by using MAP crystallization technology

The invention discloses a method for demulsifying emulsified wastewater. The method comprises the following steps: replenishing Mg2<+>, NH4<+>, and PO43<-> ions to the wastewater, regulating a pH value, creating MAP crystallization conditions, and completing the demulsification and oil-removing process along with the generation of the crystallization. A principle of the method is that a more compact combination is formed because of the action of electrostatic attraction and chemical bonds between an MAP crystal and an emulsification ingredient, the emulsification ingredient is precipitated with the MAP crystal along with the generation and the sedimentation of the MAP, and the 'demulsification', 'oil-removing', and 'COD-removing' processes are synchronously completed. Presented in the macroscopic scale, the emulsification state of the wastewater is damaged, the clear and transparent state is presented, and a precipitate is generated. Compared with the common method for the emulsified wastewater treatment which is demulsification firstly and removes the COD secondly, two processes are completed in one step according to the MAP crystallization method, the reaction is rapid, and two processes are synergetic. The removal efficiency is good, and supernatant liquid is more limpid. According to the method, the COD, which is less than 10000 mg / L, of the emulsified wastewater is treatedto be the COD which is less than 2000 mg / L, and the load of the follow-up biochemical treatment is greatly reduced. The sedimentation velocity of sludge is rapid, the amount of the sludge is small and the dewaterability is good.
Owner:BEIJING MUNICIPAL RES INST OF ENVIRONMENT PROTECTION

Composition for repairing skin barrier and application thereof

The invention provides a composition for repairing a skin barrier. The composition comprises a lucid ganoderma extract and an ion regulator, and the ion regulator comprises calcium ions, magnesium ions, sodium ions, potassium ions and chloride ions. The invention further provides application of a composition for preparing a preparation for treating skin diseases or improving skin discomfort or abnormal symptoms caused by the diseases, and the composition is as mentioned above.
Owner:PANION & BF BIOTECH INC

Organic photochromic material and preparation method and application thereof

ActiveCN110423607AAchieving a specific responseAchieve idiosyncratic responseOrganic chemistryFluorescence/phosphorescenceFiltrationMolecular switch
The invention provides an organic photochromic material based on diarylethene, and a preparation method and an application thereof in ion regulation and molecular recognition. A structural formula ofthe material is shown as a general formula I, wherein X is selected from a halogen atom (Cl, Br, I), H, a C1-C12 alkyl group, or a phenyl group. The preparation method of the material includes the following steps: reacting a diarylethene-based monoaldehyde compound having the photochromic performance with 3-hydroxy-2-naphthoic acid hydrazide at the temperature of 20-120 DEG C for about 1-24 hours,forming precipitation in a solution and after the reaction is stopped, and subjecting the precipitate to filtration, washing, and purification to obtain a novel Schiff base photochromic compound based on the diarylethene. The ion regulation switching spectral properties and ion recognition properties of the organic photochromic material of the invention have very important functions in the fieldof photoelectric information, such as preparation of multi-addressing photoelectric molecular switches, molecular conducting wire components, photochromic light-emitting devices, and the like.
Owner:SHANGHAI UNIVERSITY OF ELECTRIC POWER

Control system of negative oxygen ion generator

The invention belongs to the technical field of negative oxygen ion generators and discloses a control system of a negative oxygen ion generator. The control system comprises a power control module, amaster control module, a negative ion regulation module, a negative ion generation module and an anomaly detection module, wherein the power control module is used for converting input mains supply into stable direct-current low voltage to be output for power supply; the master control module is connected with the power control module, the negative ion regulation module, the negative ion generation module and the anomaly detection module and used for regulating normal work of the modules. The negative ion regulation module is used for regulating negative ion energy, negative ion production quantity and the like, and output of negative ions with controllable frequency and output quantity is realized; by means of the anomaly detection module, abnormal discharge caused by faults of the negative ion generator can be known timely and accurately, and convenience is provided for further timely fault clearing. The control system can further save electricity and energy.
Owner:XIANGYA HOSPITAL CENT SOUTH UNIV

Magneto-electric coupling device

The invention relates to a magneto-electric coupling device. The magneto-electric coupling device comprises a conductive substrate, a transition metal oxide layer and a magnetic metal layer. The transition metal oxide layer is arranged on the surface of the conductive substrate. The transition metal oxide layer is a mixture composed of SrCoO2.5 and HSrCoO2.5, wherein SrCoO2.5 accounts for 0-100%.The magnetic metal layer is arranged on the surface of the transition metal oxide layer, and the transition metal oxide layer is arranged between the conductive substrate and the magnetic metal layer.The magneto-electric coupling device can achieve the regulation and control of the magneto-electric coupling effect through low mobility of hydrogen ions and / or oxygen ions. The magneto-electric coupling device provided by the invention can realize the magneto-electric coupling effect with low power consumption, high response speed and room temperature adjustability. According to the magneto-electric coupling device, the device cost can be greatly reduced, the integration level can be improved, and the magneto-electric coupling device capable of promoting the ion regulation can be advanced into the application field.
Owner:TSINGHUA UNIV

A kind of preparation method of bentonite for drilling mud

The invention discloses a preparation method of bentonite for drilling mud. The method includes the steps of mining, sodium ion exchange capacity analysis, sodium ion regulation, accumulation sodium modification, drying and crushing, etc. The invention has the advantages that: the preparation method is simple, the use effect is good, the bentonite obtained by the method can be used to resist seawater and chemical polluted water, and can completely block seawater and chemical polluted water.
Owner:董宪姝

Ion conditioning agent and application thereof in method for measuring content of fluorine in aluminum fluoride

InactiveCN107192629AGood detection conditionsShort melting time at low temperatureWeighing by removing componentUsage analysisOperation safety
The invention discloses an ion conditioning agent and application thereof in a method for measuring the content of fluorine in aluminum fluoride, and belongs to the technical field of aluminum smelting. The problems that the content of fluorine in aluminum fluoride cannot be accurately and rapidly measured in the prior art are solved. The method comprises the steps of sample solution preparation, standard solution preparation, ion conditioning agent preparation, curve plotting, sample concentration measuring and calculation of the content of fluoride in the solution. The novel ion conditioning agent is built, the pH value of the detected solution is adjusted to 5-6, the detection conditions of a fluoride ion selective electrode reach the optimum, and the solution is close to the existing form of fluorine and sodium; the sample processing time is shortened, and the fluoride content is rapidly and accurately measured; a small amount of analytical reagent is adopted, and the analytic cost is low; the technological process is non-toxic, and operation is safe; the operation cost is low, analysis is rapid, and manpower is saved.
Owner:GANSU DONGXING ALUMINUM

Manganese ion regulation of reverse transcriptase activity and methods of modulating same

InactiveUS20050123624A1Promote infectionInhibit and reduce activity of proteinCompound screeningBiocideReverse transcriptase activityCell biology
Methods of identifying agents that modulate reverse transcriptase activity in a cell by affecting manganese ion transport across a membrane of the cell are provided, as are agents identified using such methods. Also provided are methods of modulating reverse transcriptase activity by effecting manganese ion concentration. In addition, methods of reducing or inhibiting infection of cells with a retrotransposable element are provided.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE

Ion regulation and control method for breeding blue crabs in inland saline-alkali soil

The invention provides an ion regulation and control method for breeding blue crabs in inland saline-alkali soil. Ca2 +, Mg2 + and K + are added into a breeding water body to improve the survival rate of the blue crabs and guarantee growth and development of the blue crabs. Wherein the adding concentration of calcium ions Ca < 2 + > is 100 mg / L or above; a magnesium ion Mg < 2 + >, which is obtained by adding magnesium chloride MgCl2 and has a concentration of 200 mg / L or more, as a specific record of an embodiment; the addition concentration of potassium ions K < + > is 80 mg / L or more. According to the ion regulation and control method for inland saline-alkali soil culture, the survival rate, the growth speed and the yield of blue crabs are effectively increased. According to an existing method, blue crabs cannot be cultured in saline-alkali soil, and the death rate is extremely high. The problems of high death rate, low yield and the like of the blue crabs cultured in the saline-alkali soil can be solved only by an ion regulation method for saline-alkali soil culture, so that the blue crabs adapt to the saline-alkali soil.
Owner:NINGBO UNIV

Self-tuning PID Ion Adjustment Method for Hemodialysis Machine

ActiveCN110812557ASolve the adjustmentSolver fluctuation problemDialysis systemsHemodialysisDatasheet
The invention relates to a self-tuning PID ion adjustment method for a hemodialysis machine, which comprises the following steps of: S100, creating a feedback data table and an initial control data table; S200, setting initial ion concentration, inquiring liquid B and conductance target before hemodialysis in feedback data table according to current dialysis flow rate and ion concentration, and inquiring pump speed in initial control data table at the same time, and sending to lower computer; S300, the lower computer comparing the current conductance value with the conductance value of the feedback data table, and performing PID adjustment if the current conductance value exceeds the preset value, wherein the PID adjustment comprises adjusting the pump speed within the set range, and saving the ion concentration after the adjustment is successful; S400, storing the pump speed after successful adjustment to the update control data table according to the corresponding ion concentration relationship, wherein the update control data table includes the ion concentration and the corresponding pump speed. The invention has the beneficial effects that the PID initial value self-correctionmethod can solve the problems of slow ion adjustment speed and easy deviation or fluctuation in adjustment in practical application.
Owner:GUANGDONG BIOLIGHT MEDITECH CO LTD

Influence of calcium ion increase rate reducing on cell death reducing with penumbral region neuron in CaV2.1 mutant mouse model

The present invention relates to the field of biomedicine, particularly to influence of calcium ion increase rate reducing on the cell death reducing with penumbral region neuron in a CaV2.1 mutant mouse model. The main cause of local ischemia caused by cell death and brain damage is abnormal Ca<2+> ion regulation. According to the present invention, in the experiment, the physiological effect of Cav2.1(P-Q type) in ischemic neuronal injury is researched with two kinds of Cav2.1 channel alpha1 subunit mutant mice (rolling Nagoya mice and leaner mice); the local ischemia experiment results show that the cerebral embolism areas of the two mutant models such as rolling Nagoya mice and leaner mice are significantly reduced compared to wild type mice; the in vitro Ca<2+> imaging research results show that the Ca<2+> concentration increase rates of the two Cav2.1 channel mutant mice are slower than the Ca<2+> concentration increase rates of wild type mice; and all the research results show that the Cav2.1 channel provides the important effects in the Ca<2+> dependent local ischemic model, and a certain prevention and protection effect can be provided if the pathway is blocked.
Owner:宁波美丽人生医药生物科技发展有限公司

Intelligent vehicle-mounted in-situ treatment and reinjection control system for oil field produced liquids

The invention relates to an intelligent vehicle-mounted in-situ treatment and reinjection control system for oil field produced liquids. The system comprises an intelligent control unit as well as anair flotation oil separation device, an oil filter-out device, an ion regulation device, a corrosion and scale inhibition regulation device, a sterilization device and a clear water injection tank which are sequentially connected, wherein the air flotation oil separation device, the oil filter-out device, the ion regulation device and the corrosion and scale inhibition regulation device are connected with the intelligent control unit. The control system is integrated into a standard container except the clear water injection tank. By means of the system, treatment and reinjection of oil fieldproduced liquids are realized, emission of the oil field produced liquids is reduced to a certain extent, environmental harm is reduced, fresh water consumption is reduced, and the water resource is saved.
Owner:QINGDAO UNIV OF SCI & TECH

Defect-sensitized lithium ferrous phosphate cathode material and preparation method thereof

InactiveCN102340003BImprove battery performanceReduced migration resistanceCell electrodesPhosphateCerium
The invention relates to a defect-sensitized lithium ferrous phosphate cathode material and a preparation method thereof, belonging to the field of power batteries. The defect-sensitized lithium ferrous phosphate cathode material is characterized by having a chemical expression of Li1-aMxFe1-zPO4 / C, wherein M is zinc, manganese, aluminum, chromium, nickel, copper, scandium, yttrium, cerium or lanthanum, a is not smaller than 0 and not more than 0.1, and x is not smaller than 1 and not more than 0.05. The invention provides the practical preparation method for successfully preparing the defect-sensitized lithium ferrous phosphate (Li1-aMxFe1-xPO4 / C) cathode material by proper ion regulation, the obtained cathode material is uniform in crystal grains and complete in structure and has a better lithium ion migration property and a wide market application prospect.
Owner:淄博中鼎锂电材料科技有限公司

Biosurfactant fermentation production technology based on trace metal ion regulation

The invention relates to a biosurfactant fermentation production technology based on trace metal ion regulation. Trace elements Fe<2+> and Mn<2+> are supplemented in a biosurfactant production bacteria culture process. Compared with the prior art, the biosurfactant fermentation production technology is characterized in that the trace elements are duly supplemented into fermentation broth on the basis of the influence of trace elements to the growth and metabolism of production strains and the change characteristics of trace elements in the fermentation broth so as to improve the growth and metabolism activity of the production strains and improve production efficiency and the yield of the biosurfactant.
Owner:EAST CHINA UNIV OF SCI & TECH

Optimized treatment method for removing heavy metals in seawater based on salinity and ion regulation

The invention provides an optimized treatment method for removing heavy metals in seawater based on salinity and ion regulation; specifically, coccoloba uvifera is put into the seawater with heavy metal ions; and the metal ions adsorbed on the surface enter algae cells through the structure of the cell wall, an ion channel on a cell membrane and a metal protein transporter, so that the aim of removing the heavy metal ions in the water body is fulfilled. The method is characterized in that before the heavy metal ions are removed, macroalgae are subjected to short-term pretreatment of salinity and deionization, diffusion of metal ions is increased by changing the permeability of algae cell membranes, and the ion competition effect is weakened; the algal cells have more sites for adsorption and absorption internalization of the heavy metal ions, so that the enrichment capacity of the algal cells on the heavy metal ions is improved, and the removal efficiency is improved. The average removal rate of the heavy metal ions in the water body reaches up to 80%, the highest removal rate reaches 90% or above, the treatment time is short, and the removal efficiency is high.
Owner:深圳市蓝汀鼎执生物科技有限公司

Preparation method of thienopyridine-type ionic rod-like liquid crystal and ionic liquid compound

InactiveCN110003232AVarious chemical structuresAdapt to the needs of different functionsOrganic chemistry methodsPlastic crystalLiquid-crystal display
The invention discloses a preparation method of a thienopyridine-type ionic rod-like liquid crystal and ionic liquid compound. The thienopyridine-type ionic rod-like liquid crystal and ionic liquid compound have structures as shown in a general formula I, a general formula II and a general formula III. Asymmetric compounds represented by the general formula I show a liquid crystal phase in a certain temperature range, and different inorganic ions and organic ions can be regulated and controlled for carrying out ion exchange. On one hand, storage and release of the inorganic ions and organic ions can be realized in a liquid crystal phase range according to needs; on the other hand, conversion between ionic liquid crystals and ionic liquid is realized through ion regulation and control, anda directional reference is provided for design and application of ion battery materials, special molecular devices and the like. The compounds represented by the general formula II and the general formula III provides another probable design and synthesis idea for the thienopyridine-type rod-like (ion) liquid crystal (plastic crystal) compound. The preparation method is short in route and high inyield.
Owner:SICHUAN NORMAL UNIVERSITY

A method for the directional preparation of low-viscosity and ultra-low-viscosity alginate by enzymatic method based on ion regulation

ActiveCN107227326BControl degradation levelLow costChemical recyclingFermentationDigestion TreatmentLyase
In order to solve the problems of serious water consumption and poor molecular weight uniformity in the traditional process, the present invention discloses a method for directional production of low-viscosity and ultra-low-viscosity alginate by enzymatic method based on ion regulation. After the brown algae is soaked, solidified and digested , transferred to the membrane bioreactor and added via K + 、Na + and Ba 2+ The alginate lyase treated with the solution is used for enzymatic hydrolysis to reduce the viscosity, and after the end, the enzyme is inactivated and filtered to obtain clear glue. The clear glue solution is then subjected to processes such as calcium precipitation, decalcification, neutralization, alcohol precipitation, and drying to obtain low-viscosity and ultra-low-viscosity alginate. The alginate product prepared by the invention has good molecular weight uniformity, and the main component content is between 80-100%. The invention has the advantages of simple process, strong continuity, less water consumption, no need for harsh conditions such as high temperature and high pressure, and overcomes the problems of long enzymatic treatment time and the like in other processes. Compared with traditional process production, it can save 60-80% of water consumption, which greatly saves the consumption of water resources.
Owner:OCEAN UNIV OF CHINA

A method of calcium ion regulating biofilm method to treat low c/n ratio wastewater and quickly form a film

The invention discloses a rapid biofilm formation method for low C / N ratio waste water treatment using a calcium ion-regulated biofilm method, belonging to the field of biofilm-process waste water treatment. The method is characterized by comprising the following steps: (1) measuring biochemical oxygen demand 5 / total nitrogen (BOD5 / TN) of the low C / N ratio waste water; (2) measuring the polysaccharide concentration of dissolved substances in the low C / N ratio waste water and the salinity of the waste water; (3) measuring the contact angle of a filler carrier used by the biofilm method for treating the low C / N ratio waste water; (4) selecting a proper regulation and control scheme according to the related measured values; (5) enabling a biofilm reactor to run, and adding a certain amount of rhamnolipid and calcium chloride into the low C / N ratio waste water every day until biofilm formation is completed. According to the rapid biofilm formation method, calcium ions are complexed with pollutants in the low C / N ratio waste water, so that the attachment and colonization of the dissolved substances and microorganisms in the waste water are accelerated, and the biofilm formation effect is further improved.
Owner:NANJING UNIV

Memristor unit based on dual-ion regulation and preparation method thereof

The memristor unit adopts a simple planar memristor structure, is simple in process, and adopts an ion intercalation process to insert a first ion and a second ion into a Van der Waals gap of a dielectric layer, so that the memristor unit is obtained. Different resistance change phenomena are generated by changing the size and the direction of an electric field applied to the memristor unit, and then the resistance change phenomena are matched with the phenomenon of combined action of multiple ions in the biological synaptic plasticity change process, so that migration behaviors of Ca < 2 + > and protein ions in the biological synaptic are simulated.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACADEMY OF SCI

Anion release unit and umbrella

The embodiment of the invention discloses a negative ion release unit and an umbrella, and the negative ion release unit comprises a release device which is set to generate and release negative ions;an adjusting and supporting device which is arranged to support the releasing device and adjust the direction and the height of the releasing device; a vertical storage device which is arranged to becapable of fixing and storing the adjusting supporting device and / or the releasing device; a vertical storage device which is provided with a fixed part capable of fixing the vertical storage device to the side face of an object. The releasing device is fixed to the first end of the adjusting supporting device, and the second end of the adjusting supporting device is fixed to the vertical storagedevice. Through the scheme of the embodiment, the omnibearing adjustment of the release device is facilitated, so the release device can be adjusted according to different heights or orientations of human bodies, the adjustment flexibility of the release device is improved, and storage and protection of the release device are realized.
Owner:鸿翌科技有限公司

A single-electrode regulated ion triode with a divergent/converging nano-flow channel structure and its characteristic adjustment method

The invention relates to a single electrode regulated ion triode with a diverging / convergent nano channel structure. The single electrode regulated ion triode comprises a substrate, an upper cover plate, regulating electrodes, driving electrodes, an insulating layer, and liquid storage pools; one driving electrode, the insulating layer, one liquid storage pool, the substrate, the other liquid storage pool, the insulating layer, and the other driving electrode are arranged from the front to the back successively; one regulating electrode, the insulating layer, the substrate, the insulating layer, and the other regulating electrode are arranged from the left to the right successively; the upper end surface of the substrate is provided with a diverging / convergent nano channel with a width of nanometer scale, and the single electrode regulated ion triode is penetrated by the diverging / convergent nano channel from the front to the back; and the upper cover plate used for covering the diverging / convergent nano channel is arranged on the substrate. The invention also relates to a characteristic adjusting method of the single electrode regulated ion triode with a diverging / convergent nano channel structure. The single electrode regulated ion triode is simpler in structure, is lower in cost, and is more convenient to prepare; real-time regulating of triode breakover current can be realized; and application prospect is promising. The invention belongs to the technical field of ion triode.
Owner:SOUTH CHINA UNIV OF TECH

Important effects of CaV2.1 channel in Ca<2+> dependent ischemic models

The present invention relates to the field of biomedicine, particularly to important effects of CaV2.1 channel in Ca<2+> dependent ischemic models. The main cause of local ischemia caused by cell death and brain damage is abnormal Ca<2+> ion regulation, and the depolarization of neuronal cell membranes causes the activation of voltage gate Ca<2+> channels and the influx of Ca<2+>. According to the present invention, in the experiment, the physiological effect of Cav2.1(P-Q type) in ischemic neuronal injury is researched with two kinds of Cav2.1 channel alpha1 subunit mutant mice (rolling Nagoya mice and leaner mice); the local ischemia experiment results show that the cerebral embolism areas of the two mutant models such as rolling Nagoya mice and leaner mice are significantly reduced compared to wild type mice; the in vitro Ca<2+> imaging research results show that the Ca<2+> concentration increase rates of the two Cav2.1 channel mutant mice are slower than the Ca<2+> concentration increase rates of wild type mice; and all the research results show that the Cav2.1 channel provides the important effects in the Ca<2+> dependent local ischemic model, and a certain prevention and protection effect can be provided if the pathway is blocked.
Owner:宁波美丽人生医药生物科技发展有限公司
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