The invention discloses an environment-friendly printing ink cleaning agent. The environment-friendly printing ink cleaning agent is prepared from castor oil polyoxyethylene ether, benzotriazole, diisobutyl phosphite, sodium palmate, 2,6-ditert-butyl-4-methylphenol, sorbitan tristearate, hydraulic oil, 2,4-dioxolane, bioctyl sulfonated sodium succinate, deodorized kerosene, stannic chloride, hydroxyethyl nethyl cellulose, propyl alcohol, hydrogen peroxide, a surfactant, a cleaning auxiliary, rosin and purified water. According to the environment-friendly printing ink cleaning agent, the production technology process is simplified, and through preparation of the raw materials, emission of hydrocarbon harmful gas in the production process can be reduced, the cleaning effect of the product can be improved, and the product smell can be reduced.