9 results about "Polyethyleneglycol stearate" patented technology

The invention provides a grinding fluid, the grinding fluid comprises a base fluid, a grinding material, nano-diamond and a dispersion stabilizer, the base fluid comprises polyether and silicone oil, the grinding material comprises surface modified silicon carbide particles, and the dispersion stabilizer comprises polyethylene glycol stearate and polyvinylpyrrolidone. The surface roughness of a grinding piece can be reduced, the scratch density and microcracks of the surface are reduced, damage of grinding fluid to the grinding piece is reduced or even avoided, and the service life of a cutter can be prolonged. The invention also provides a preparation method of the grinding fluid and a process method using the grinding fluid.

The invention belongs to the technical field of lubricating oil for vehicle power systems, and discloses electric displacement oil as well as a preparation method and application thereof. The electric displacement oil is prepared from the following components in parts by weight: 75 to 95 parts of synthetic base oil, 0.5 to 10 parts of a lubricant, 1.5 to 5 parts of a viscosity index improver, 0.2 to 3 parts of an antioxidant, 0.1 to 1.5 parts of a purification dispersant, 0.1 to 2 parts of an antirust agent, 0.2 to 3 parts of a pour point depressant, 0.1 to 1.5 parts of an air releasing agent and 0.1 to 1.2 parts of an antistatic agent, the synthetic base oil comprises fatty acid ester and poly-alpha-olefin; the fatty acid ester comprises lauric acid-2-ethylhexyl ester; the antistatic agent comprises polyethylene glycol stearate and octadecyl diethanolamine in a mass ratio of (1-5): 1. The electric drive oil has excellent lubricating performance, wear resistance, foam resistance, corrosion resistance and antistatic performance, is not prone to spontaneous combustion and low in noise during use, can meet the use requirements of an electric drive system of a new energy automobile, reduces dry friction between parts in the start-stop process, reduces wear, improves the reliability of the system and prolongs the service life of the system.

The invention relates to the technical field of biological medicines, in particular to a peptide composition for treating allergic skin diseases, which comprises a lipid nanoparticle carrier, an active component, a stabilizer and deionized water, the lipid nanoparticle carrier is prepared from acetylated dioleoyl phosphatidyl glycerol, cholesterol and polyethylene glycol-100 stearate; the acetylated dioleoyl phosphatidyl glycerol is obtained by modifying dioleoyl phosphatidyl glycerol through an acetylation reagent; the active component is arginine / lysine polypeptide; the stabilizer is trehalose. According to the invention, acetylation-modified dioleoyl phosphatidyl glycerol is used for constructing a lipid nanoparticle carrier, and the lipid nanoparticle carrier is matched with an active component and a stabilizer to form the composition; the acetylated carrier can improve the stability and skin absorption efficiency of active ingredients and assist the active ingredients to play an anti-allergic role so as to treat allergic skin diseases, and meanwhile, the arginine / lysine polypeptide is cooperated with other components, so that the problem of facial contour aging caused by the skin diseases can be improved.

This invention relates to a metal injection molding titanium alloy feedstock and its preparation method. By mass percentage, its components include: 60%-75% Ti-6Al-4V powder; 15%-20% binder; and 10%-20% pore-forming agent. The binder, by mass percentage, includes: 55%-60% polyethylene glycol, 22%-26% polyvinylpyrrolidone, 10%-13% polyethylene glycol stearate, and 3%-8% mannitol. The use of a specialized binder solves the problems of poor compatibility with binders, easy agglomeration of the feedstock, uneven dispersion of the pore-forming agent, and low pore connectivity during porous structure preparation.

The application discloses a composition and a preparation method of a ripretinib cream, the composition comprising: an active ingredient of ripretinib or a pharmaceutically acceptable salt thereof and excipients, wherein the excipients include an emulsifier, a humectant, a solvent, a bacteriostatic agent, a hardener, a sealing agent, an emollient and a chelating agent; the emulsifier includes polysorbate 60 and polyethylene glycol-7-stearate, and no thickening agent is additionally added in the ripretinib cream composition. The ripretinib cream composition has the advantages of simpler preparation process, fewer excipients, smaller droplet particle size of the produced cream, no precipitation of the raw material drug in the process of use, and equivalent clinical efficacy to the original Opzelura TM . The ripretinib cream composition has the advantages of simpler preparation process, fewer excipients, smaller droplet particle size of the produced cream, no precipitation of the raw material drug in the process of use, and equivalent clinical efficacy to the original Opzelura TM .

The application relates to the technical field of coating, in particular to an alumina ceramic coating of a vacuum electrostatic chuck, a preparation method and application, which comprises a conductive bottom layer and a ceramic surface layer, the conductive bottom layer comprises the following raw materials in parts by weight: 3-8 parts of a conductive phase additive, 2-4 parts of polyethylene glycol stearate and 1-3 parts of silicon carbide whiskers, and the ceramic surface layer comprises the following raw materials in parts by weight: 85-92 parts of alpha-alumina powder, 4-10 parts of borosilicate glass powder, 0.5-2 parts of magnesium oxide, 1-3 parts of zirconium oxide and 3-5 parts of polyethylene glycol. The conductive property, mechanical durability and environmental adaptability of the prepared coating are matched with each other, the service life of the vacuum electrostatic chuck is prolonged, the equipment maintenance frequency is reduced, and the coating has good conductivity, wear resistance and adhesion strength.

An immediate-release liquid oral suspension of Eslicarbazepine Acetate, containing between about 5 to about 10 g of active ingredient per 100 mL, along with carbomer homopolymer and microcrystalline cellulose as viscosity modifying agents. It may further comprise, parabens as antimicrobial agent, sucralose as a sweetener, and polyethylene glycol 8 stearate as a surfactant. The suspension is designed to provide bioequivalence to marketed Eslicarbazepine Acetate tablets, ensuring rapid drug release and stability over extended storage periods. The pH is adjusted to 3.0-6.5 to maintain stability, with impurities remaining under 0.05% of the eslicarbazepine content after stress storage conditions. This formulation offers an alternative to solid dosage forms for patients with partial-onset seizures.

The invention relates to the technical field of coatings, in particular to an aluminum oxide ceramic coating of a vacuum electrostatic chuck and a preparation method and application thereof.The aluminum oxide ceramic coating comprises a conductive bottom layer and a ceramic surface layer, and the conductive bottom layer is prepared from, by weight, 3-8 parts of conductive phase additives, 2-4 parts of polyethylene glycol stearate and 1-3 parts of silicon carbide whiskers; the ceramic surface layer is prepared from the following raw materials in parts by weight: 85 to 92 parts of alpha-aluminum oxide powder, 4 to 10 parts of borosilicate glass powder, 0.5 to 2 parts of magnesium oxide, 1 to 3 parts of zirconium oxide and 3 to 5 parts of polyethylene glycol. The conductive property, the mechanical durability and the environmental adaptability of the prepared coating are matched with one another, the service life of the vacuum electrostatic chuck is prolonged, the equipment maintenance frequency is reduced, and the coating has good conductivity, wear resistance and adhesive strength.

The invention belongs to the technical field of pharmaceutical preparations, and relates to a pharmaceutical composition containing Efiniprofen, a patch and a preparation method, the pharmaceutical composition containing Efiniprofen comprises the following components in parts by mass: 1.5-5.0 parts of Efiniprofen or pharmaceutically acceptable salts thereof, 1.0-5.0 parts of a penetration enhancer, and 0.1-10 parts of a stabilizer; the stabilizing agent is selected from one or more of octyl and decanoic acid coconut oil ester, isopropyl myristate, octyl and decanoic acid polyethylene glycol glyceride, polyethylene glycol-7 stearate and glyceryl monostearate and glyceryl distearate. According to the invention, the content reduction of the efiniprofen or the pharmaceutically acceptable salt during the stability period is effectively inhibited, and the stability is further improved, so that the pharmaceutical composition containing the efiniprofen can be stored for a long time; meanwhile, the in-vitro release effect of the pharmaceutical composition containing the iflurprofen is further improved.