The invention provides a refining method of N,N'-bis(2, 2, 6, 6-tetramethyl-4-piperidyl)-1, 6-hexamethylenediamine. The method comprises the following steps: taking 2, 2, 6, 6-tetramethyl-4-piperidone and 1,6-hexamethylenediamine as raw materials to react to prepare an N,N'-bis(2, 2, 6, 6-tetramethyl-4-piperidyl)-1, 6-hexamethylenediamine reaction solution; rectifying the reaction solution, and evaporating out light components and a crude product; and recrystallizing the crude product in a second solvent to obtain a target product. According to the invention, the purification process is effectively simplified, the problem of complex process caused by repeated concentration and crystallization of the crystallization mother liquor is avoided, and the product has more stable performance, can be stored for a long time and is not easy to discolor.