36results about How to "Effective particle size control" patented technology

The invention relates to a preparation method of a liposome entrapping water-soluble medicines. According to the invention, a water-soluble medicine is dissolved in amino-acid-structure-containing high-molecular hydrophilic colloids such as gelatin, collagen or albumin; poloxamer is added and the mixture is well mixed, such that a W/W type colloidal solution is formed; the solution is lyophilized; the formed lyophilized powder is transferred into a tert-butanol solution containing a liposome material, and the mixture is well dispersed; and the mixture is subjected to lyophilization, such that high-entrapment-efficiency liposome entrapping the water-soluble medicine is formed. According to the liposome preparation method, W/W type colloid is combined with a two-step lyophilization preparation technology, such that problems such as low water-soluble medicine load, low entrapment efficiency and poor stability of existing preparation methods of liposome entrapping water-soluble medicines are solved. The method provided by the invention is used for preparing liposome used for entrapping water-soluble medicines, and is especially suitable for preparing liposome used for entrapping poor-thermal-stability or macromolecular medicines. The method can also be used for covering medicine bitterness or odor, and for separating medicines from other components.

The invention relates to a preparation method of a pyrite-type ferrous disulfide micron/nano crystalline material with a controllable morphology. The method comprises the following steps of: (1) respectively adding solvent dimethyl sulfoxide into compounding agent thioglycolic acid and surfactant polyvinylpyrrolidone under the condition of agitating and leading in nitrogen or argon, and obtaining a solution A by mixing and agitating; (2) orderly adding an iron source and a sodium thiosulfate water solution into the solution A, leading in the nitrogen or argon and vigorously stirring to obtain a solution B; (3) transferring the solution B into a reaction kettle and reacting for 4-12 hours at 120-180 DEG C after uniformly agitating, to obtain pyrite-type ferrous disulfide suspension liquid; (4) centrifugally separating, washing for a plurality of times and drying the pyrite-type ferrous disulfide suspension liquid in vacuum to constant weight to obtain the pyrite-type ferrous disulfide micron/nano crystalline material. The product obtained by the method has controllable particle size and morphology, good process repeatability and stable quality, and is expected to be applied to the fields such as photovoltaic conversion and lithium ion battery materials.

The invention provides a non-ionic compound gas hydrate anti-agglomerant which consists of an alkyl polyglycoside non-ionic surfactant and a polyhydric alcohol non-ionic surfactant in a weight ratio of (0.01-100):1. The gas hydrate anti-agglomerant is used for anti-agglomerating treatment of an oil-gas-water three phase mixed conveying system, wherein the volume of water accounts for less than or equal to 60% of the total volume of oil and water. The invention further provides an anti-agglomerating method adopting the non-ionic compound gas hydrate anti-agglomerant. The method comprises the step of adding the non-ionic compound gas hydrate anti-agglomerant into the oil-gas-water three phase mixed conveying system. The non-ionic compound gas hydrate anti-agglomerant provided by the invention is suitable for oil-gas-water three phase co-existing systems and is less in use level, good in biodegradability, economic and environmental friendly and remarkable in anti-agglomerating effect.

The invention belongs to the field of new chemical materials and in particular relates to a carbon quantum dot/attapulgite nanocomposite as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing citric acid, hydrogen peroxide and attapulgite, carrying out hydrothermal reaction, and then centrifuging, washing and drying, so that the carbon quantum dot/attapulgite nanocomposite is obtained, and then the nanocomposite is used for photocatalytic desulphurization.

The present invention discloses a preparation method for cubic precipitated calcium carbonate. The method comprises the following processes: transporting refined and aged lime cream into a carbonation bubbling reactor with stirring, injecting purified and cooled limekiln gas to carry out carbonation reaction, when pH of the reaction mixture drops to 7.0, stopping the carbonation reaction, and controlling specific surface area (BET) of the finished calcium carbonate between 20-35 m<2>/g. Adding accelerating curing agent, heating to performing curing, maintaining the temperature between 60-90 DEG C for 2-15 hours, adding a surface treating agent, stirring the materials for 60 minutes to obtain a slurry of calcium carbonate, and subjecting the slurry to pressure filtration for dewatering, drying and pulverizing to obtain the calcium carbonate product. Compared with traditional heating curing methods, the present method has a higher curing efficiency, and obtains large cubic precipitated calcium carbonate particles in short time; size control and pH value control are more effective and more stable; the processed are simple and feasible, the costs are low, and economic effectiveness is good.

The invention discloses a niobium-doped lithium-rich manganese-based layered oxide cathode material, which has the chemical formula of Li1.20-XNbxMn0. 54Co0. 13Ni0. 13O2 (0 <= x <= 0. 10). The invention adopts a polymer template method to prepare, the main steps are as follows: the dried cross-linked poly (acrylamide-methacrylic acid) microspheres are immersed in an aqueous solution containing Mn2+, Co2 + and Ni2 + ions of urea, the solution is adsorbed completely, and then heating and drying are performed; the dried microspheres are added into a solution containing lithium salt and niobium salt, heating is performed to remove moisture, and obtaining a lithium-rich cathode material precursor is obtained; the obtained precursor is calcined in air at high temperature to obtain a product-Niobium-doped lithium-rich manganese oxide base cathode material. As that crosslink polymer microsphere is used as a template, the transition metal hydroxide nanoparticle are synthesized in situ, the morphology of the lithium-rich manganese base oxide positive electrode material can be effectively regulated and the electrochemical performance can be greatly improved, and the preparation process of the niobium-doped lithium-rich manganese-based layered oxide cathode material is simple, the particle morphology is good in reproducibility, and the niobium-doped lithium-rich manganese-based layered oxide cathode material is suitable for industrial production.

The invention discloses equipment for preparing nano powder by an electrical explosion method, and belongs to the field of nanomaterial preparation. The equipment aims at solving the problem that the conventional nano powder production equipment has a strict requirement for an insulating structure and an insulating material of a high-voltage part. The equipment comprises a nano powder reaction mechanism, an electrical explosion generation mechanism, a wire feeding mechanism matched with the nano powder reaction mechanism, an air cooler, a first connecting tube, a first insulating tube, a second connecting tube, a second insulating tube and a third connecting tube. According to the equipment, instant high voltage is generated by electrodes, so that materials in an explosion reaction cavity react to generate corresponding nano particles. Due to an improvement of a structure, the working voltage of the equipment is equal to or lower than 25KV, and a high-voltage part has a very low requirement for a high-voltage structure and a withstand voltage material. In addition, raw materials of the equipment are filamentary materials and non-insulators, so that the equipment has the characteristics of wide raw material source and high adaptability, and has good universality for various filamentary non-insulator materials.

The invention discloses a preparation method of a high-purity nylon regenerated material, and the method comprises the following steps: firstly, a nylon waste material is dissolved into an acidic goodsolvent under the conditions of stirring and a constant temperature water bath; after dissolving for a certain period of time, a certain volume of nylon dissolving solution is taken and continuouslystirred by a magnetic stirrer, and a weakly alkaline precipitation precipitating agent is slowly added into the nylon dissolving solution; then, solid-liquid separation is carried out to separate a nylon polymer from the solution to obtain a nylon precipitate and a solution, and the solution can be recycled; deionized water is added to the nylon precipitate, and the nylon precipitate is centrifugally washed by a centrifuge; finally, a washed nylon aggregate is dried under vacuum to obtain the high-purity nylon regenerated material. The process adopted by the invention does not need high-temperature and high-pressure equipment, is simple, convenient and easy to implement, reagents used are low in cost, efficient and environment-friendly, and the prepared nylon regenerated material has narrow particle size distribution, good fluidity, high purity and no impurities.

The invention belongs to the technical field of zeolite molecular sieve synthesis, and particularly relates to a synthesis method of a particle-size-controllable needle-shaped ZSM-5 molecular sieve. The particle size and shape of zeolite are important factors affecting the catalytic property of the molecular sieve. According to the synthesis method, by simply adjusting the polymerization degree ofa silicon source and an aluminum source and adopting a mixed template agent, the particle size of the zeolite can be controlled effectively, and meanwhile, the needle-shaped zeolite is obtained. Thesynthesis method is very simple and convenient in synthesis step and very easy to industrialize. A sample XRD and an SEM display change of the silicon polymerization degree so that the particle size of the zeolite can be controlled effectively.

The invention discloses a method for preparing nanometer aluminum hydroxide powder by using an electrochemical method. The method for preparing the nanometer aluminum hydroxide powder by using the electrochemical method comprises the steps of: electrolyzing aluminum, and then washing, hydro-thermally processing, washing and drying electrolysate to obtain the nanometer aluminum hydroxide powder, wherein the particle size range is 10-80 nm. By adjusting a current, a voltage and a pH and adopting a hydro-thermal treatment technology, the method for preparing the nanometer aluminum hydroxide powder by using the electrochemical method realizes efficient control on the particle size of the aluminum hydroxide powder. The nanometer aluminum hydroxide powder obtained by the method is simple in preparation process, and short in production period; and the nanometer aluminum hydroxide powder is high in productivity and good in product stability, and has no pollution to the environment. The nanometer aluminum hydroxide powder prepared by the method is widely applied to the industries such as chemical industry, painting, building materials, wires, cables and rubber products.

The invention discloses a styrene-acrylic resin for toner and a preparation method thereof. The styrene-acrylic resin for toner is prepared from a hard monomer, a soft monomer, a functional monomer, a chain transfer agent, an emulsifier, an initiator, a pH regulator and water. The preparation method comprises the steps of: 1) preparation of a seed pre-emulsion; 2) preparation of a pre-emulsion; 3) preparation of a seed emulsion; 4) preparation of a styrene-acrylic emulsion; and 5) demulsification and spray drying of the styrene-acrylic emulsion, thus obtaining the styrene-acrylic resin for toner. The preparation method provided by the invention has the advantages of simple preparation process, short reaction period, mild reaction conditions, no need of special instrument and equipment, and the reaction medium is water, which has small odor, and is economical and environment-friendly. The styrene-acrylic resin for toner provided by the invention can achieve regulation of molecular weight, glass transition temperature, softening point and other properties according to actual needs, has low water absorption, good thermal stability and excellent performance, and is economical and practical.

The invention discloses a preparation method of a catalyst for synergistic removal of hydrogen sulfide and elemental mercury in garbage gasification pollutants, and belongs to the technical field of catalyst preparation. The preparation method comprises the following steps of: selecting an MCM-41 molecular sieve as a raw material, and introducing a hydrophobic group SiH4 to modify the outer surface of the molecular sieve; then removing a template agent by using a certain amount of anhydrous ethanol/HCl; introducing an -SH group to modify the inner surface of the molecular sieve; and then loading a salt solution of lanthanum, cerium and iron in the modified molecular sieve, performing drying, and then conducting high temperature roasting to obtain the multi-metal oxide molecular sieve composite material used for researching the synergistic control of garbage pyrolysis gasification pollutants. The prepared catalyst has good adsorption capacity and regeneration capacity within the temperature range of 150DEG C-200DEG C, H2S and Hg<0> can be efficiently and synergistically removed, and compared with the prior art, multiple pollutants are purified at the same time, and the investment cost and the operation cost can be effectively reduced.

The invention relates to a magnetic composite nanomaterial and a preparation method and application of the magnetic composite nanomaterial. In particular, the invention discloses a nanocomposite taking a metal-doped ferrite material as a core and an acid-responsive mesoporous material as a shell. The magnetic nanocomposite can enhance the MRI T1 weighted imaging effect based on magnetic resonanceharmonic theories. The magnetic nanocomposite is applied to magnetic resonance imaging, thereby being capable of obtaining a high-quality MRI contrast agent with obviously excellent imaging performances, high acid sensitivity and rich T1 signals, so that the identification and detection of serious diseases such as tumors can be improved by the contrast agent to obviously reduce errors in medical image detection and treatment costs.

The invention provides nano barium titanate microcrystals and a preparation method thereof, and barium titanate powder and a preparation method thereof, and relates to the technical field of nano materials. The preparation method of the nano barium titanate microcrystals comprises the following steps of: a nano titanium dioxide aqueous dispersion with the mass concentration of not less than 20% and a barium hydroxide aqueous solution are rapidly mixed to allow the temperature of the obtained mixed system to be at least 2 DEG C lower than the temperature of the barium hydroxide aqueous solutiondue to the rapid mixing of the two; under an inert atmosphere, the mixed system is subjected to normal pressure hydrothermal synthesis reaction at 90-110 DEG C, and reaction products are collected, washed and dried to obtain the nano barium titanate microcrystals. According to the preparation method of the nano barium titanate microcrystals, the nano barium titanate microcrystals with small particle diameter, uniform particle diameter distribution and high purity can be obtained, and the high-quality barium titanate powder can be obtained by calcining the nano barium titanate microcrystals serving as a raw material.

The invention discloses a novel granularity-controllable sucrose refining method which comprises the steps: dissolving and decoloring food-grade sucrose to obtain refined filtrate, concentrating and crystallizing the refined filtrate to obtain sucrose crystals, and purifying and drying the sucrose crystals to obtain medicinal-grade sucrose crystal grains. A crystallization method combining seed crystal graining and ultrasonic stimulation assisted graining is creatively adopted; the seed crystal adding time, the seed crystal adding amount, the ultrasonic frequency, the ultrasonic stimulation crystallization time, the stirring speed and other parameters are accurately controlled; the method effectively controls the particle size of the medicinal sucrose crystals, enhances the sucrose crystallization yield, and implements the characteristics of small particle size, favorable flowability and favorable solubility of the medicinal sucrose crystals, thereby satisfying the performance requirements for the medicinal sucrose auxiliary material in the direct-pressure solid preparation.

The invention discloses a method for preparing metal particles through continuous electrochemical deposition. The method comprises the main steps: firstly, by controlling electrodeposition parameters,evenly-dispersed metal particles are electrodeposited on a movable substrate; then the movable substrate carry the electrodeposited metal particles, and the substrate and materials on the substrate are cleaned or subjected to surface treatment; and finally, the particles on the surface of the substrate are stripped through methods such as physical stripping, and the particles are dispersed in a solution to be collected. The method has the advantages that the metal particles are prepared through an electrodeposition electronic reduction method, wherein the particle diameter of the metal particles is even, the metal particles are evenly dispersed, and the surfaces of the metal particles are free of active agents; and contact force between the particles and the substrate is small so that theparticles can be collected through simple physical stripping, in the whole synthesis process, the particle size is controllable, an electrolyte can be reutilized, compared with a traditional method for synthesizing the metal particles, the cost is low, and the size is controllable.

The invention discloses a device for preparing metal particles through continuous electrochemical deposition. The device mainly comprises an electrodeposition tank (an anode, electrolyte and a cathode), a cleaning tank, a collecting tank (a collecting part) and the like. The device has the advantages that the whole electrodeposition collecting process is completed in one device, the cathode is designed to be in a reciprocating rotating strip shape and is organically combined with the collecting device, and the two processes cannot interfere with each other due to the modular design; a mechanical stripping method is adopted for collecting the metal particles, so that a large amount of surface active reagents of a traditional chemical synthesis method are avoided; the electrolyte can be repeatedly used in the whole synthesis process, a large amount of organic additives are not needed, and the environmental benefit is excellent; and the device is good in universality and suitable for various metals.

The invention discloses a high-stability nano platinum-based intermetallic compound direct methanol fuel cell electrocatalyst and a preparation method thereof. The preparation method comprises the steps that firstly, a layer of polyaniline is subjected to in-situ oxidative polymerization on the surface of a Pt/C catalyst, transition metal ions are adsorbed, and then a salt-sealed and cured sample is obtained through curing and packaging treatment with an inorganic salt solution; then under high-temperature driving, the transition metal ions are reduced into transition metal atoms under the reduction effect of nitrogen-doped carbon formed through polyaniline carbonization, the transition metal atoms are gradually diffused into Pt crystal lattices, and Pt-based alloy is formed; and Pt and transition metal atoms are subjected to atom rearrangement at a high temperature, and finally, the Pt and the transition metal atoms are mutually converted to form the nano Pt-based intermetallic compound. According to the invention, by constructing an inorganic salt@PANI@Pt/C-transition metal ion system, an alloying-ordering process from pure Pt nanoparticles to a Pt-based intermetallic compound is realized in one step by means of high-temperature thermal driving, and low platinization and stabilization of the direct methanol fuel cell electrocatalyst are realized.