30results about How to "Generate none" patented technology

The invention discloses a synthetic method of N-(2-benzimidazolyl)-methyl carbamate. The method comprises the steps of by taking hydrogen cyanamide, methylclhlorofonmate and o-phenylenediamine as materials, adding strong alkali and weak acid salt in synthetic process; adding the strong alkali and weak acid salt to control the pH value of a reaction system in the reaction process, achieving the target of feeding once to control the pH of two-step reaction by the buffer effect, wherein the strong alkali and weak acid salt can be combined with and consume hydrogen chloride generated in the first step of reaction to counteract ammonia generated in the second step of reaction. The synthetic method is simple to operate, high in yield, and environment-friendly; the cost of acid-base is reduced; generation of impurities in reaction is reduced; and no waste water or residue is generated.

The invention relates to a method for preparing hydroxyalkyl disiloxane. The method includes the following steps: (1) mixing carboxylic acid unsaturated ester with dimethylchlorosilane in an organic solvent, introducing inert gas, adding hydrosilyation catalyst and stirring for 2 to 12 hours; (2) dropwising a mixed liquid of acidic aqueous solution and the organic solvent to the hydrosilylation reaction product and hydrolyzing for 1 to 6 hours; (3) regulating the hydrolysis product pH to be neutral, extracting organic layers three times with extraction agent, washing three times, drying for 24 hours and removing the extraction agent by rotary evaporating to obtain the finished product. The method has the advantages of simple operation, simple steps, mild reaction conditions, pure product and high yield, and the yield of the hydrosilylation reaction product can reach 83.2% and the yield of the hydrolysis product can reach 89.5%.

The invention discloses a method for treating irrigation sediment by using a surfactant pretreatment-hydrothermal oxidation-thermal cracking coupling method. The method comprises the following steps of firstly, adding a surfactant to preliminarily destroy an oil-water mixed system and an oil-mud colloid system; performing pretreatment filtration dehydration, deeply destroying an emulsifying structure and a micellar structure by utilizing the characteristic of high ionization degree of water in a hydrothermal oxidation process and utilizing the oxidation characteristic of an oxidant, carrying out thermal catalytic oxidation on pretreated and dehydrated tank bottom muddy water, filtering, further dehydrating to obtain crude oil containing a very small amount of water and mud, filtering the crude oil containing a very small amount of water and mud, and separating the crude oil and oil-containing mud sand, recovering the crude oil; and carrying out thermal cracking on the separated mud sand containing a small amount of crude oil to recycle part of light oil so as to obtain mud sand with the organic matter content of less than 1%. The method is simple and convenient in operation process, the equipment requirement is low, the method is green and environment-friendly, the technical difficulties of low energy consumption and high cost in the prior art can be solved, and technical advantages and engineering application value are large.

The invention discloses a combustible solid waste pyrolysis device and a pyrolysis method. The pyrolysis device comprises a fluidized bed pyrolysis reactor and a fluidized bed combustion reactor whichadopt heat carrier bed material interactive circulation. Combustible solid waste fuel is pyrolyzed in the fluidized bed pyrolysis reactor, and a heat carrier bed material overflows and is sent to thecombustion reactor through a star-shaped return feeder; the heat carrier bed material is heated again by utilizing heat released by pyrolysis oil gas combustion in the combustion reactor; and the heated heat carrier bed material enters the pyrolysis reactor again through a fluidized bed return feeder. Heat generated by combustion is transmitted to a pyrolysis process by utilizing interactive circulation of the heat carrier bed material between the two reactors, so that the problem of non-uniform temperature in reactors caused by heat transfer of conventional reactors is solved; the star-shaped return feeder for pyrolysis material returning achieves a good sealing effect, the fluidized bed material return feeder for combustion material returning avoids high oxidation and deformation of mechanical moving parts, and meanwhile the solid circulation flux can be controlled.

The invention discloses a lanthanide rare earth ion doped bismuth titanate monocrystal thin slice and a preparation method thereof. The lanthanide rare earth ion doped bismuth titanate monocrystal thin slice is 5-10 microns in length and 50-200nm in thickness. The preparation method comprises the following steps of: 1, preparing a lanthanide rare earth ion doped bismuth titanate precursor solution by adopting ethylene glycol monomethyl ether as a solvent according to an element molar ratio of Bi:R:Ti=(4-x):x:3 in a formula Bi4-xRxTi3O12 (R is a lanthanide rare earth element, and x is more than 0 and is less than or equal to 1.5); 2, adding an NaOH aqueous solution into the precursor solution, and then filtering to obtain a deposit; and 3, uniformly stirring the deposit, heating the deposit in a reaction kettle, and cleaning and drying a product after reaction to obtain the lanthanide rare earth ion doped bismuth titanate monocrystal thin slice. According to the preparation method, an organic solvent is used as a main reaction medium, and a hydrolysis reaction caused by a lot of water is effectively avoided, so that the generation of an impurity phase is avoided. The lanthanide rare earth ion doped bismuth titanate monocrystal thin slice prepared by the preparation method is large in size and high in purity without the generation of the impurity phase.

The invention relates to the technical field of protein modification, and particularly relates to a preparation method for protein fixed-point pegylation modification. The preparation method for protein fixed-point pegylation modification comprises the step that in the presence of vitamins and/ or coenzymes, 5 kD-40kD polyethylene glycol derivatives with the mass 3-7 times that of protein react with the protein. According to the preparation method, a new modification method is adopted for conducting pegylation modification of rhG-CSF, the reaction condition is mild, NADP <+> is generated afterthe reaction, and no harmful substance is generated; meanwhile, the preparation method is high in polyethylene glycol modification yield, the yield reaches 80% or above, the uniformity is high, the modification site is the first amino acid methionine Met at the N terminal of the protein rhG-CSF, and the stability is good; in addition, the modification reaction can be terminated by directly adjusting the acid, the termination process is simple, and the commercialized production cost is greatly reduced.

The invention discloses a preparation method for water-soluble natural vitamin E. the method comprises the steps that chloromethylated polystyrene resin and PEG1000 serve as raw materials, alkali serves as a catalyst, and reaction is carried out in an organic solvent at 45-135 DEG C so as to obtain PEG1000-loaded resin; under the action of the catalyst, 4-dimethylaminopyridine (DMAP) and tetrahydrofuran, water division reflux reaction is carried out on the PEG1000-loaded resin and d-alpha-tocopherol succinate so as to obtain TPGS-loaded resin; and after the TPGS-loaded resin is soaked by usingmethylbenzene, ethanol, palladium carbon and pyridoxal phosphate are added, and under the atmosphere of 0.8-1.5 MPa of hydrogen , stirring is carried out for reaction for 24 hours at the temperatureof 100-110 DEG C so as to obtain d-alpha-tocopherol polyethylene glycol succinate. According to the synthetic method, the yield of TPGS can reach 97.8%, the TPGS monoester content is 98.6%, and the TPGS diester content is 0.

The invention discloses a sulfonic acid zinc metal organic complex, which relates to the technical field of organic synthesis, the complex is 8-aminoquinoline 1, 5-naphthalene disulfonic acid zinc metal complex, the chemical formula of the 8-aminoquinoline 1, 5-naphthalene disulfonic acid zinc metal complex is Zn (8-aql)2(1,5-nd).2H2O, the invention also provides a preparation method of the complex, which comprises the following steps: reacting zinc nitrate hexahydrate, sodium azide, 1, 5-naphthalene disulfonic acid sodium salt and 8-aminoquinoline in secondary deionized water at 120-180 DEG Cfor 3 days, cooling to room temperature, filtering, and washing to obtain the complex. The invention also provides the application of the complex in detection of carbon disulfide and nitrobenzene. The 8-aminoquinoline 1, 5-naphthalene disulfonic acid zinc metal complex has the beneficial effects that the 8-aminoquinoline 1, 5-naphthalene disulfonic acid zinc metal complex prepared by the method can be used for detecting low-concentration carbon disulfide in the environment and can also be used for detecting low-concentration nitrobenzene in the environment.

The invention discloses raw material components of a CLSY non heavy metal emission metal surface treatment fluid and a preparation method of a product and belongs to the field of new materials or fine chemical industry. The CLSY non heavy metal emission metal surface treatment fluid has the innovative points that alcohol and water are used as solvents to replace an organic solvent which has influence on environment and belongs to water soluble coatings; compounds of Al3+, Mg2+ and Zn2+ with very strong rust prevention capability are used to replace heavy metal compounds as a rust inhibitor (the Al3+, the Mg2+ and the Zn2+ cannot be oxidized and rusted under any condition); and benzoyl peroxide with stronger passivation ability is used to replace Cr7+, strong resin is used as a film forming agent, and a rough high-temperature-resistant protective paint film can be formed on the metal surface. When the CLSY non heavy metal emission metal surface treatment fluid is prepared and applied, three wastes are not discharged, and various disadvantages of the traditional phosphating solution are completely overcome; an application method is simple and can use all of coating methods including a spraying method, a brushing method, a rolling method and a soaking method; after the product is tested, a good conclusion is obtained; and the CLSY non heavy metal emission metal surface treatment fluid creates an innovation road with good effect, resource saving, energy saving and environmental protection on metal surface treatment.

The invention belongs to the technical field of organic chemical synthesis, particularly relates to a triazole synthesis method and aims at using methyl ethyl ketazine to replace hydrazine hydrate so as to provide a low-cost and high-yield 1,2,4-triazole preparation method. The technical scheme is that the triazole synthesis method comprises the following steps of enabling ammonia, hydrogen peroxide and butanone to react with the presence of formamide to prepare the methyl ethyl ketazine; separating an upper-layer oil phase containing the methyl ethyl ketazine from a water phase containing the formamide, evaporating the ammonia, the butanone and water in the water phase to recover the formamide; rising the temperature of the formamide to be 165 DEG C-190 DEG C, then dropwise adding the oil phase into the formamide, performing heat preservation reaction at the temperature ranging from 165 DEG C to 190 DEG C for 20-60 minutes, recovering incompletely-reacted methyl ethyl ketazine through distillation to obtain 1,2,4-triazole. By means of the triazole synthesis method, the 1,2,4-triazole with purity higher than 95% can be obtained, and the yield is higher than 95% (by formamide).

The invention discloses anti-oxidization oxytetracycline hydrochloride injection and a preparation method thereof and relates to the technical field of medicines. The anti-oxidization oxytetracyclinehydrochloride injection is prepared from the following raw materials in parts by weight: 35 to 55 parts of anti-oxidization oxytetracycline hydrochloride, 12 to 15 parts of miloxacin, 10 to 15 parts of enoxacin, 6 to 7 parts of p-acetamidophenol, 22 to 26 parts of herba taraxaci-radix isatidis extracting solution, 6 to 8 parts of glucose, 5 to 8 parts of sodium chloride, 2 to 4 parts of calcium chloride, 3 to 5 parts of zinc sulfate, 80 to 100 parts of ethanol, 16 to 20 parts of triethanolamine, 13 to 16 parts of vitamin C and 180 to 240 parts of purified water; the anti-oxidization oxytetracycline hydrochloride is prepared through a specific method and is matched with other raw materials to use, so that the prepared injection has antibacterial, sterilization and inflammation-diminishing effects; meanwhile, the injection has stable properties and is not easily oxidized and the medicinal effect can be kept for a long period; the injection also can provide necessary nutrients for life bodies, is applicable to disease prevention and bacterium resistance of domestic fowl, domestic animals and large-size animals and has a remarkable curative effect.

The invention relates to the technical field of supramolecular catalysis. The invention discloses a method for preparing an anthracycline dimer through photocatalysis. An anthracycline derivative is used as a reaction substrate, a metal-organic cage compound is used as a catalyst, a reaction cavity is provided, the anthracycline derivative can be converted into a corresponding anthracycline dimerwith high selectivity in an air atmosphere through irradiation of a light source under the participation of a cocatalyst, generation of reaction byproducts is avoided, reaction conditions can be widened, and mild synthesis in the air atmosphere is realized. In addition, by selecting a metal center, active Ni<2+> is introduced into the system, and the efficiency of the photodimerization reaction can be actively promoted. Compared with the prior art, the method provided by the invention has the characteristics of mild reaction conditions, convenient detection, high specific selectivity, no generation of by-products and the like, and has very good application prospects in the fields of photocatalytic dimerization reaction systems and the like.

The invention relates to a synthesis method for preparing 2,3-epoxypinane by epoxidizing alpha-pinene, and belongs to the field of chemical synthesis. The invention provides a method for preparing the2,3-epoxypinane by epoxidizing the alpha-pinene. The method includes the following steps: directly taking an anthraquinone working solution carrying hydrogen peroxide after catalytic hydrogenation and oxidation as an oxidant; adding the anthraquinone working solution into a reactor mixed with the alpha-pinene, bicarbonate and a catalyst for reaction; and filtering, layering, cleaning and decompressing rectification after the reaction is finished to obtain the 2,3-epoxypinane. The method has the characteristics of low cost, mild reaction conditions, convenient operation, fast reaction speed, high conversion rate, good selectivity and the like, and the process is safe and reliable and pollution-free.