The invention discloses a method for preparing mulberry brandy, which comprises the following steps of: inspecting, accepting, selecting, pulverizing and pulping the raw material, sterilizing the mulberry pulp at the temperature 110-115 DEG C for 3-6 s, fermenting the mulberry pulp, adjusting the temperature of the mulberry pulp to 18-25 DEG C, adding active dry yeast, and starting temperature controlled fermentation, wherein the mass ratio of the active dry yeast to the mulberry pulp is 1-1.2:10000, the fermentation time is 7-10 days, and the fermentation temperature is 18-25 DEG C; and completing fermentation when the content of residual sugar is less than or equal to 5.0 g / L, transferring the fermentation liquor into a storage tank, waiting for distillation, distilling the fermentationliquor in two steps of rough distillation and fine distillation, storing, brewing, blending and adjusting raw brandy, and storing, brewing and filtering semi-finished brandy to obtain the mulberry brandy. By using the preparation method, the raw material of mulberries can be fully utilized, the mulberry brandy has the advantages of abundant nutrient components and high product added value, rancidity is not easy to occur, and the disposal of pollutants can be effectively lowered so as to protect environmental sanitation.