The present invention discloses a baking soda production anti-caking process and apparatus, and the main feature is that in the production process of baking soda, the dried baking soda is not directly packaged, first, agglomerates in the material are crushed by a cyclone sieve, meanwhile large particles are sieved out, the sieved material enters into a powder flow cooler for cooling and packaging. The dried baking soda is first crushed by the cyclone sieve, then cooled by the powder flow cooler, and packed, the finished baking soda agglomeration phenomenon can be eliminated; by selection of the cyclone sieve, while sieving, agglomerates formed in the drying process can be crushed, compared with a loud noise vibrating screen, the work environment is favorable to the health of an operator; the powder flow cooler has a simple structure, high heat transfer efficiency, low energy consumption, no damage of crystalline particles, no pollution emissions, low operation and maintenance costs, small floor space and other advantages; the produced baking soda product has high quality, is not contaminated, and fully meets food grade requirements.