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47results about How to "Strong response signal" patented technology

Construction and application of SPR sensor based on amplification effect of magnetic molecularly imprinted polymer

The invention provides construction of a surface plasma resonance sensor based on the amplification effect of a magnetic molecularly imprinted polymer and the application of the surface plasma resonance sensor in pesticide detection, and belongs to the technical field of surface plasma resonance sensing. Chlorpyrifos is regarded as a template molecule firstly; the magnetic molecularly imprinted polymer which has recognition action on the chlorpyrifos is compounded by adopting the self-polymerization performance of dopamine; after elution is performed on the chlorpyrifos, the magnetic molecularly imprinted polymer containing imprinted cavities has good superparamagnetism and high selectivity; the specific interaction between acetylcholinesterase fixed on the surface of a gold sheet and the chlorpyrifos is adopted to construct a pesticide residue recognition, detection and sensing interface on the basis of the amplification effect of the magnetic molecularly imprinted polymer. Compared with the conventional pesticide residue detection technology, the surface plasma resonance sensor on the basis of the amplification effect of the magnetic molecularly imprinted polymer has high detection sensitivity and good selectivity to chlorpyrifos detection, and has an excellent application prospect.
Owner:NANCHANG UNIV

Graphene oxide/AgInS2 nano hybrid material and preparation method thereof

InactiveCN103043709ADiffusion rate is notDiffusion rate is not too fastGraphiteGallium/indium/thallium compoundsAlcoholNano hybrid
The invention belongs to the technical field of nano hybrid materials, and particularly relates to a graphene oxide / AgInS2 nano hybrid material and a preparation method thereof. AgInS2 nano particles are modified on the surface of the graphene oxide. The preparation method of the graphene oxide / AgInS2 nano hybrid material includes the steps of evenly dispersing graphene oxide in oleic acid, adding octadecene and oleylamine respectively, and mixing; adding the mixed liquor of graphene oxide slowly into the mixed liquor of oleic acid containing In (DEDC) 3 and Ag (DEDC); and moving to a reaction kettle for reaction after stirring, adding absolute ethyl alcohol for precipitation after cooling, centrifugally washing the precipitate and drying. The graphene oxide / AgInS2 nano hybrid material is good in stability, low in LOD (limit of detection) of NO2<-> and capable of being used in detection of food such as sausage, pot-stewed products and the like; and the preparation method has the characteristics of facilitation of operation, wide raw material source, low production cost, non-toxic and the like, and is suitable for industrial production.
Owner:SHANGHAI NORMAL UNIVERSITY

Cu2Se-Pd hybrid material as well as preparation method and application thereof

The invention discloses a preparation method of a Cu2Se-Pd hybrid material and a prepared material. A copper source is tetrachloro cupric (II) acid tetraethylammonium, and a selenium source is a mixed liquid formed by dissolving SeO2 into terpilenol. The preparation method comprises the following steps: performing reaction in DMPU (dimethyl propyl urea) to obtain hexagonal phase CuSe or cubic phase Cu2-XSe by virtue of adopting a solid-liquid phase synthetic method; further extracting a product by virtue of TOP to obtain mono-clinic phase Cu2Se; compounding the mono-clinic phase Cu2Se with noble metal Pd to prepare the Cu2Se-Pd hybrid material. The method disclosed by the invention can be used for synthesizing the nano-level Cu2Se-Pd hybrid material under normal pressure and relatively low temperature, and is simple in process and short in reaction time; the prepared hybrid material can be used as an SERS (surface enhanced raman spectroscopy) substrate so as to be applied to SERS detection 4-Mpy, and is strong in response signal and high in selectivity; the limit of detection can reach 10<-9>molL<-1>. Compared with independent semiconductor Cu2Se and metal Pd, the Cu2Se-Pd hybrid material shows more excellent SERS performances.
Owner:NANJING NORMAL UNIVERSITY

Instrument-free enzyme-linked immunosorbent assay method

The invention discloses an instrument-free enzyme-linked immunosorbent assay method. According to the method, an antigen-antibody specific immune reaction is carried out in a 96-pore plate so as to capture an analyte antigen or antibody in a sample; nanoparticles are introduced to catalyze a reaction for generating nanogold between chloroauric acid and a reducing agent; a watch or a mobile phone is used for recording the time required for mixed solution to become red, so as to complete instrument-free enzyme-linked immunosorbent assay, wherein the time is negatively correlated to the concentration of a target antigen or antibody in the sample. According to the method, widespread watches or mobile phones are used for carrying out signal reading, so that the cost of quantitative analysis isreduced. Through collaborative use of lipidosome for wrapping plenty of nanoparticles and efficient catalytic activity of the nanoparticles for the reaction of reducing the chloroauric acid by the reducing agent to generate the nanogold, the response signals for the specific binding reaction of single antigen-antibody are amplified, so that the detection sensitivity is improved.
Owner:GUILIN UNIVERSITY OF TECHNOLOGY

Application of self-assembled film in surface auxiliary laser desorption or ionization flying time mass spectrum

The invention discloses application of a self-assembled film in a surface auxiliary laser adsorption or ionization flying time mass spectrum. The application is characterized in that the invention relates to the application of the self-assembled film made of an aromatic thiol compound in the surface auxiliary laser adsorption or ionization flying time mass spectrum. The application comprises the following steps of: firstly, preparing the aromatic thiol compound self-assembled film for surface auxiliary laser desorption or ionization of small molecules, namely preprocessing a silicon slice, sequentially sputtering Ti and Au on the preprocessed silicon slice to obtain a golden substrate, and putting the golden substrate into an ethanol solution with the aromatic thiol compound for generating self-assembling reaction to obtain the aromatic thiol compound self-assembled film; and then drying small-molecular sample points on the surface of the obtained self-assembled film, and placing the self-assembled film into an MALDI-TOF-MS mass spectrum for analysis. The application has the advantages that the substrate is stable; an Au layer is difficult to fall off; the small peptide and the traditional Chinese medicine active components can be conveniently and quickly analyzed; an analysis effect is good; and a response signal is high.
Owner:张琦

Side-excited loop source ground well transient electromagnetic detection method and system

The invention relates to a transient electromagnetic detection method and system, belongs to the technical field of geophysical exploration, and specifically relates to a side-excited loop source ground well transient electromagnetic detection method and system. By exciting an anomalous body from the side through an ungrounded loop, a good coupling effect can be produced on a steep or upright low-resistance slab body. By using a receiving device to receive secondary field signals in a roadway or borehole, strong response signals can be received. By using a proposed data processing method to invert the received signals, an accurate interpretation result can be obtained.
Owner:XIAN RES INST OF CHINA COAL TECH& ENG GROUP CORP

Ground-in-hole combined detecting system based on time domain electromagnetic method and application method thereof

The invention discloses a ground-in-hole combined detecting system which comprises an electromagnetic instrument, a transmitting device, a rod-shaped receiving device, a transmitting-receiving fixingframe, a wall abutting type rotation preventer and a pushing rod. The electromagnetic instrument supports sequential intelligent starting and stoppage of single or a plurality of transmitting devicesand a plurality of receiving channels. A transmitting coil in the transmitting device is arranged on an annular frame. The upper end and the lower end of the rod-shaped receiving device are respectively provided with a pushing rod joint and a rotation preventer joint. In ground detection, the rod-shaped receiving device is arranged in the sleeve of a transmitting-receiving fixing frame. In in-holedetection, the rod-shaped receiving device is connected with the wall abutting type rotation preventer and performs in-hole movement by means of the pushing rod. An application method based on the detecting system of the invention mainly comprises ground and in-hole detection. According to a ground field source excitation characteristic, the application method can be divided into a fixed-source excitation mode, a movable-source excitation mode and a multi-source successive excitation mode, and single-hole or multiple-hole receiving. The ground-in-hole combined detecting system and the application method have advantages of reducing one-time field interference and humanistic electromagnetic interference, realizing high signal-to-noise ratio, improving detecting precision and realizing three-dimensional space detection to periphery of a drilling hole.
Owner:安徽晟北辰地质勘测设计有限公司

Metal pipeline detecting system and method based on time-domain electromagnetic method

The invention discloses a metal pipeline detecting system based on a time-domain electromagnetic method. The metal pipeline detecting system has a proximal connecting point, a distal connecting point,a transmitter, a transmitting connecting line, a measuring machine and a receiving device. The system has a rectangular detecting area of which the short side is perpendicular to the approximate direction of a target pipeline, and of which the long side is parallel to the approximate direction of the target pipeline. The proximal connecting point is located at an exposed point of the target pipeline and corresponds to a vertex of the rectangular detecting area. The distal connecting point is located at a vertex of the rectangular detecting area adjacent to the proximal connecting point. The transmitting connecting line is disposed on the side of the detecting area. The receiving device is connected to the measuring machine through a mounting frame. The measuring machine and the transmitter are timed and set parameters before detection. The system has the advantages that the to-be-detected section of the target pipeline is directly put in the transmission loop in order to guarantee that an excitation field source is applied to the target pipeline to the utmost extent, a response signal is stronger and the side electromagnetic interference can be reduced, and the to-be-detected pipeline can be precisely positioned, orientated and continuously tracked.
Owner:安徽晟北辰地质勘测设计有限公司

Preparation method and applications of current mode immuno-sensor for detecting breast cancer

The invention belongs to the fields of novel nano materials, immuno-assay, and biosensor, provides a preparation method and applications of a current mode immuno-sensor for detecting breast cancer, and specifically relates to a construction method of an electrochemical immuno-sensor, which is made of a graphene nano composite material based on palladium loaded nano rod copper oxide functionalization, and an application of using the electrochemical immuno-sensor to detect a specific antigen of breast cancer.
Owner:SHANDONG UNIV OF TECH

Ractopamine molecularly imprinted SPR (surface plasma resonance) sensor chip as well as preparation method thereof

The invention relates to the field of SPR sensor chips, and particularly relates to a ractopamine molecularly imprinted SPR sensor chip as well as a preparation method thereof. A ractopamine molecularly imprinted polymer, graphene nanogold, and 1-octyl-3- methylimidazole hexafluorophosphate are taken as chip substrate modifiers for the ractopamine molecularly imprinted SPR sensor chip. The ractopamine molecularly imprinted SPR sensor chip provided by the invention has high-specificity adsorption capability to ractopamine, and has obvious response signal variation to low-concentration ractopamine in samples. The ractopamine molecularly imprinted SPR chip prepared by the invention is simple in steps, is short in analysis time, and has relatively high accuracy and flexibility when being used for analyzing the low-concentration ractopamine residue.
Owner:INST OF QUALITY STANDARD & TESTING TECH FOR AGRO PROD OF CAAS

ELISA (enzyme-linked immuno sorbent assay) method based on pH (potential of hydrogen) meter

ActiveCN104849443AEasy to detectIncrease the amount of immobilizationBiological testingSaccharic acidSpecific immunity
The invention discloses an ELISA (enzyme-linked immuno sorbent assay) method based on a pH (potential of hydrogen) meter. The ELISA method comprises the following steps of performing antigen-antibody specificity immune reaction in an ELISA plate, capturing the antigen or antibody of the analyzing matter in a sample, introducing the glucose oxidase-glucose biological catalytic reaction, and using the pH meter to measure the pH value of the mixed product solution containing the glucose, wherein the size of the pH value is negatively related with the concentration of the analyzing matter in the sample, so as to complete the ELISA based on the pH meter. The ELISA method has the advantages that the signal is read by the low cost pH meter, so the cost of quantitative analysis is reduced; the response signal of single antigen-antibody bonding reaction is amplified by the micrometer or nanometer immobilized glucose oxidase; while the good specificity of the traditional ELISA method is maintained, the immobilizing amount of the glucose oxidase is increased by the micrometer or nanometer particles; the response signal of the single antigen-antibody specificity bonding reaction is amplified, and the detection sensitivity is improved.
Owner:GUILIN UNIVERSITY OF TECHNOLOGY

Sensor chip and manufacturing method thereof

The invention relates to a sensor chip and a manufacturing method thereof, and belongs to the technical field of designing and manufacturing of surface plasma resonance sensor chips. The chip adopts a composite structure formed by a glass substrate, a metallic film, a self-assembly film, and a metallic oxide and polymer composite thin film, in sequential arrangement from bottom to top; and nanometer metallic oxide is successfully fixed to the surface of the sensor chip by a polymer embedding method, so that the detection range of objective gas is effectively enlarged, and the sensitivity of the objective gas is effectively improved. The method disclosed by the invention is simple, the manufactured sensor chip has high sensitivity on sulphur dioxide, detection requirements under room temperature condition are met, and the sensor chip has favorable response signals within 5 ppm-40 ppm.
Owner:中国人民解放军92232部队 +1

Preparation method of electrochemical sensor for detecting molecular imprinting of organophosphorus pesticide residue

The invention discloses a preparation method of an electrochemical sensor for detecting molecular imprinting of organophosphorus pesticide residue. The method comprises the following steps of: firstly preparing a solution from the raw molecules of organophosphorus pesticide serving as imprinting molecules and a functional monomer and an electrolyte; depositing the molecular imprinting polymer on the surface of a working electrode by an electrochemical polymerization method so as to finish the preparation of a molecular imprinting sensitive film; and removing the imprinting molecules of the organophosphorus pesticide from the molecular imprinting sensitive film by a proper elution method and a proper eluent so as to finish the preparation of the electrochemical sensor. The method disclosed by the invention has the advantages of fast response, high sensitivity and good selectivity; and meanwhile, the detection method is simple and quick, has strong adaptability after being popularized and particularly strong universality in pesticide detection, and has a wide market prospect.
Owner:XIAN MEDICAL UNIV

Silicon-doped graphene, preparation method of silicon-doped graphene and silicon-doped graphene-based chemical resistance type nitric oxide room-temperature sensor

The invention provides silicon-doped graphene, a preparation method of the silicon-doped graphene and a silicon-doped graphene-based chemical resistance type nitric oxide room-temperature sensor, andbelongs to the field of gas sensors. A closed container is used as a reaction container. When a reactant system is put into the closed container at room temperature, quantitative inert gas can be introduced into the closed container according to needs so as to keep different pressure intensities. In the subsequent heat treatment process, easy-to-decompose components in graphene oxide powder and asilane coupling agent are generated in the form of gas and are kept in the closed container tube to generate positive pressure, so that the internal pressure of the closed container is increased to different degrees, and silane coupling agent fragments are promoted to be bonded on a graphene oxide matrix to a greater extent from the perspective of chemical equilibrium.
Owner:LANZHOU UNIVERSITY

Silicon oil detector, electric terminal assembly and silicon oil detector use method

The present invention relates to a silicon oil detector, an electric terminal assembly and a silicon oil detector use method. The invention discloses the silicon oil detector, which comprises an electric conduction layer, wherein the electric conduction layer adopts an organosilicon polymer material as a matrix material, the organosilicon polymer material is added with electric conduction particles, and the organosilicon polymer material swells when the electric conduction layer contacts silicon oil so as to increase electric resistance of the electric conduction layer. According to the present invention, when the organosilicon polymer base electric conduction layer contacts the silicon oil, the organosilicon polymer material rapidly swells, such that the electric resistance of the organosilicon polymer base electric conduction layer is significantly changed, and the alarm signal is sent according to the change of the electric resistance; the silicon oil detector has characteristics of strong response signal, rapid response and lasting response so as to conveniently and timely find the oil leakage phenomenon; and the organosilicon polymer base silicon oil detector is not affected by water, such that the organosilicon polymer base silicon oil detector is suitable for outdoor.
Owner:TYCO ELECTRONICS (SHANGHAI) CO LTD +1

Mercury ion electric sensing analysis and detection method based on excision enzyme III assisted target circulation and subject and object recognition

The invention discloses a mercury ion electric sensing analysis and detection method based on excision enzyme III assisted target circulation and subject and object recognition. The mercury ion electric sensing analysis and detection method comprises the following steps that a glassy carbon electrode is polished, ground and cleaned; nanogold is subjected to electrolytic deposition on the surface of the glassy carbon electrode, and thus a nanogold modified electrode is prepared; aminated beta-cyclodextrin is modified on nanogold particles to prepare a beta-cyclodextrin modified electrode, Hg<2+> is added into a mixed solution of DNA A1 and DNA A2 to form a double-chain solution; ferrocene marked DNA A3 is added into the double-chain solution to be incubated, and thus a T-shaped DNA structure is formed; exonuclease III is added into the T-shaped DNA structure to form a mixed solution; the mixed solution is dropwise added to the surface of the beta-cyclodextrin modified electrode; the modified electrode is immersed into a testing base solution to detect the electrochemical properties of the modified electrode, and quantitative measurement of Hg<2+> is achieved according an electrochemical signal; and the linearity and the selectivity of an electrochemical biological sensor are tested.
Owner:CHONGQING UNIV OF ARTS & SCI

Sensor chip capable of being used for sulfur dioxide detection and preparation method of sensor chip

The invention relates to a sensor chip capable of detecting sulfur dioxide under normal temperature conditions and a preparation method thereof, belonging to the technical field of surface plasmon resonance sensor chip design and preparation. The structure of the sensor chip includes: a glass substrate, a metal film, a self-assembled film, and a guanidine-containing polymer film; the invention synthesizes a new compound monomer by using a guanidine compound and an acrylic compound. After self-assembly modification on the surface of the gold-plated glass substrate, a guanidinium-containing polymer film was prepared on the surface plasmon resonance sensor substrate by thermal polymerization. The sensor can detect sulfur dioxide gas under normal temperature conditions, and has fast detection response speed and high sensitivity; it can be applied to SPR detection, electrochemical detection and QCM detection.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

Terahertz radio frequency signal detector based on metasurface optical antenna and preparation method

PendingCN112216763AEasy to distinguishStrong localized surface plasmon sensing capabilityFinal product manufactureAntennasUltra high speedRadio frequency signal
The invention discloses a terahertz radio frequency signal detector based on a metasurface optical antenna and a preparation method. The detector comprises a substrate, a doping layer, a silicon dioxide layer, a metasurface optical antenna layer, an ohmic electrode, a Schottky electrode and a common electrode. The width of the metasurface optical antenna layer is 2-100 mm, and the metasurface optical antenna layer comprises a first metal layer used for detecting radio frequency S wave band signals or C wave band signals or X wave band signals and a second metal layer used for detecting terahertz signals. Since the first metal layer and the second metal layer respectively have extremely strong local surface plasmon induction capability on radio frequency and terahertz signals, once local surface plasmon oscillation is generated with a corresponding signal, the response speed belongs to ultra-high-speed response, and an extremely strong response signal can be generated in an extremely short time, so that the detector can better distinguish an electromagnetic signal of a terahertz radio frequency band. In addition, due to the fact that the super-surface optical antenna is manufacturedthrough the nanometer technology, the terahertz radio frequency signal detector is very small in size and very light in weight.
Owner:HUAZHONG UNIV OF SCI & TECH

Preparation method and application of mHPBs-Hemin/rGO marked electrochemical immunosensor

The invention belongs to the technical fields of novel nanomaterials, immunoassay and biosensing detection and provides a preparation method and application of an mHPBs-Hemin / rGO marked electrochemical immunosensor. According to the preparation method, a mesoporous hollow Prussian-blue nanocube spaced hemin functional graphene porous composite is used as a current signal amplifying mechanism and introduced into construction of the electrochemical immunosensor for the first time, a current response signal is amplified efficiently, and quantitative and sensitive detection of aflatoxin is realized. The electrochemical immunosensor is easy and convenient to operate, low in cost, high in sensitivity and wide in detection range and has important scientific significance and application value forquantitative and sensitive detection of aflatoxin.
Owner:SHANDONG UNIV OF TECH

Visual optic sensing method for detecting target-mediating agglutination reaction of nano-gold probes on the basis of Tyndall effect

The invention discloses a visual optic sensing method for detecting a target-mediating agglutination reaction of nano-gold probes on the basis of Tyndall effect. In the method, by means of an analyticsubstance in a sample solution, a reaction solution, which contains a target capable of mediating the agglutination reaction of naked nano-gold probes or biofunctionalized composite nano-gold probes,can be obtained; then the reaction solution is mixed and reacted with a nano-gold probe solution in order to observe an optical signal of the Tyndall effect of the mixed solution under laser beam formed by a laser pen or a laser device, wherein the signal intensity is in positive correlation with the concentration of the analytic substance. Through a cheap portable device for reading the signal (i.e. the optical signal of the Tyndall effect), low-cost portable quantitative detection of the analytic substance is achieved. The method has simple operations and low cost, is free of special analytic instruments and equipment and is suitable for on-site analysis and real-time detection, and can be directly promoted in the fields such as medical diagnosis, environment monitoring, food safety andthe like.
Owner:GUILIN UNIVERSITY OF TECHNOLOGY

Cytochrome C based two-channel ratio type hydrogen peroxide biosensor, and preparation method and application thereof

The invention belongs to the technical field of biosensor detection, and discloses a cytochrome C based two-channel ratio type hydrogen peroxide biosensor, comprising an Au / MPA / Cyt. C electrode and anAu / FcHT reference channel electrode. The invention further discloses a preparation method and an application of the cytochrome C based two-channel ratio type hydrogen peroxide biosensor. By adoptionof the cytochrome C based two-channel ratio type hydrogen peroxide biosensor disclosed by the invention, concentration of hydrogen peroxide can be quantitatively detected.
Owner:SHANGHAI INST OF QUALITY INSPECTION & TECHN RES

Protein C activity determination kit based on chromophoric substrate method

The invention discloses a protein C activity determination kit based on a chromophoric substrate method, protein C is a vitamin K dependent plasma serine protease zymogen, and comprises a reagent R1, a reagent R2 and a diluting reagent; the R1 reagent comprises a protein C activator, a first buffer solution and a first auxiliary material; the R2 reagent comprises a chromogenic substrate Pca-5297, a second buffer solution and a second auxiliary material; the diluting reagent comprises a third buffer solution and a third auxiliary material, and the pH of the first buffer solution, the pH of the second buffer solution and the pH of the third buffer solution are 7.2-7.6; the protein C activator and the chromophoric substrate Pca-5297 are matched for use, during detection, the cutting efficiency is high, the reaction signal is strong, the reaction speed is high, the sensitivity is high, the linear range is wide, the reaction time is short, the sample distinction degree is increased, and establishment of the linear range and clinical sample testing are facilitated; the reagent is liquid, convenient to use, low in cost and good in stability.
Owner:SHENZHEN DYMIND BIOTECH

A graphene/β‑ga based 2 o 3 Schottky junction deep ultraviolet light photodetector and preparation method thereof

The invention discloses a graphene / beta-Ga<2>O<3>-based schottky junction deep ultraviolet photodetector and a preparation method thereof. The deep ultraviolet photodetector is characterized in that with a metal copper sheet as a substrate, a schottky structure of a beta-Ga<2>O<3> single crystal wafer and graphene is fixed on the substrate; according to the schottky structure, a chromium / gold electrode is arranged on an unpolished surface of the beta-Ga<2>O<3> single crystal wafer and a graphene film is arranged on a polished surface; the surface of the chromium / gold electrode is evenly coated with silver paste; the beta-Ga<2>O<3> single crystal wafer and the substrate are bonded through the silver paste; and an extraction electrode is led out at one side of the graphene film. With a schottky junction formed by the beta-Ga<2>O<3> and the graphene as a core of a device, the deep ultraviolet photodetector disclosed by the invention can utilize the sensitivity of the beta-Ga<2>O<3> to a deep ultraviolet light and can also combine excellent characteristics of low resistivity, high transmittance and the like of the graphene. Therefore, the deep ultraviolet photodetector has high absorptivity on the deep ultraviolet light.
Owner:HEFEI UNIV OF TECH

Infrared radio frequency signal detector based on metasurface optical antenna and preparation method thereof

The invention discloses an infrared radio frequency signal detector based on a metasurface optical antenna and a preparation method of the infrared radio frequency signal detector. The infrared radiofrequency signal detector comprises a substrate, a doping layer, a silicon dioxide layer which are sequentially arranged from bottom to top, and a metasurface optical antenna layer which is manufactured on the doping layer and forms Schottky contact with the doping layer, an ohmic electrode which is manufactured on the doping layer and forms ohmic contact with the doping layer, and a Schottky electrode and a common electrode that are located on the upper surface of the silicon dioxide layer. The metasurface optical antenna layer is of an array structure composed of a plurality of metal layersarranged at intervals, the metal layers comprise a first metal layer and a second metal layer, the first metal layer is a metal nano tip array with a width of 0.5-5mm and a periodic nano tip structure, and the second metal layer is a metal array with a width of 5-100mm and is composed of micron elements arranged periodically; the metasurface optical antenna layer has a local surface plasmon effecton incident infrared, radio frequency S, C or X waveband signals, and signal detection with a high response speed can be completed with a small size.
Owner:HUAZHONG UNIV OF SCI & TECH

A kind of tebuconazole molecularly imprinted membrane electrode, portable sensor and its use method and application

The invention provides a tebuconazole molecularly imprinted membrane electrode. The tebuconazole molecularly imprinted membrane electrode comprises a substrate electrode, gold nanoparticles, sulfydryl graphene, gold-prussian blue and a tebuconazole molecularly imprinted membrane, wherein the gold nanoparticles, the sulfydryl graphene and the gold-prussian blue are modified on the surface of the substrate electrode in sequence; the tebuconazole molecularly imprinted membrane is attached to the surface of the gold-prussian blue; the tebuconazole molecularly imprinted membrane is a polymer of ortho-aminophenol and m-dihydroxybenzene taking tebuconazole as a template molecule. When the tebuconazole molecularly imprinted membrane electrode provided by the invention is applied to quantitative detection, the detection limit can be up to 1.63*10<-8>mol / L, and high sensitivity is achieved. By adopting the tebuconazole molecularly imprinted membrane electrode, a probe molecule, namely, prussian blue is fixed on the tebuconazole molecularly imprinted membrane electrode, so that direct measurement of a non-electroactive target compound in a sample can be realized, and a sensor is easier and more convenient to operate, and is suitable for rapid on-site detection.
Owner:ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES

Application of spr sensor based on the amplification effect of magnetic molecularly imprinted polymers in the detection of pesticides

InactiveCN103424381BIncreased number of imprinted sitesImprove bindingMaterial analysis by optical meansChlorpyrifosPesticide residue
The invention relates to the construction of a surface plasmon resonance sensor based on the amplification effect of magnetic molecularly imprinted polymers and its application in pesticide detection, belonging to the technical field of surface plasmon resonance sensing. It first uses chlorpyrifos as a template molecule, and uses the self-polymerization property of dopamine to synthesize a magnetic molecularly imprinted polymer that can recognize chlorpyrifos. After elution of chlorpyrifos, the magnetic molecularly imprinted polymer containing the imprinted cavity has good superparamagnetism and high selectivity. Using the specific interaction between acetylcholinesterase immobilized on the surface of the gold sheet and chlorpyrifos, a magnetic-based molecularly imprinted polymer was constructed. Molecularly imprinted polymer amplification effect pesticide residue recognition and detection sensing interface; compared with traditional pesticide residue detection technology, the surface plasmon resonance sensor based on the magnetic molecular imprinted polymer amplification effect constructed by the present invention has high detection sensitivity for chlorpyrifos And selectivity is good, has very good application prospect.
Owner:NANCHANG UNIV

A biological non-toxic, degradable high-sensitivity temperature sensor chip and its preparation method and application

The invention discloses a biologically non-toxic and degradable high-sensitivity temperature sensing chip and a preparation method and an application thereof. The temperature sensing chip provided bythe invention includes a chip body which is filled with conductive liquid and is made of a degradable polymer material. The solvent of the conductive liquid is either water or alcohol, and the soluteis sugar, high-molecular polymer, inorganic salt, acid or inorganic base. Compared with the traditional temperature sensing chip, the temperature sensing chip of the invention is biologically non-toxic and degradable, has no pollution to the environment, is harmless to the human body, is smaller and cheaper, has a simple structure, is convenient to operate, has high response sensitivity, is convenient to carry and cheap, and can be mass-produced.
Owner:RENMIN UNIVERSITY OF CHINA

Colibacillus O157:H7DNA label-free detection device and method based on LAPS and ZnO nanorod array

ActiveCN110849957AEnable label-free detectionLabel-free detection is fastMicrobiological testing/measurementMicroorganism based processesEngineeringBiology
The invention discloses a colibacillus O157:H7DNA label-free detection device and method based on LAPS and ZnO nanorod array. The device comprises a Faraday shield box, a loading table, a semiconductor laser, an LAPS sensor, a manostat, a lock-in amplifier, an acquisition card, and a computer. The method comprises of performing bacterial culture, extracting colibacillus O157:H7DNA, manufacturing aLAPS sensor and modifying a ZnO nanorod; modifying probe chain DNA on a surface of the LAPS sensor, and scanning an I-V curve; fitting an optimal calibration curve detecting concentration of O157:H7DNA through traversing and a least square method; and analyzing an I-V curve of a to-be-tested sample solution and voltage offset V and substituting into the calibration curve, and calculating concentration of the to-be-tested sample. The method realizes label-free detection of O157:H7 DNA, and has advantages of short time, low cost, convenience in operation, 3D site for O157:H7 DNA hybrid, and high sensitivity.
Owner:XI AN JIAOTONG UNIV
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