The invention discloses senile-resistant multi-effect spray, which is prepared from the following ingredients including homosalate, octocrylene, C12-15 alkyl benzoate, ethanol/water, ethylhexyl salicylate, isopropyl palmitate, hydrolecithin/Sorbeth-20 beewax, butyl methoxyl dibenzoylmethane, squalene, 1,2-pentanediol, glycerol, embryo extracts, Gentian extracts/butanediol, tocopheryl acetate, rhodiola crenulata root extracts, propanediol/bisabolol/PEG-40 hydrogenated castor oil, caprylyl glycol/1,2-pentanediol, ethylhexylglycerin, xanthan gum, acrylic acid (ester) type/ethenol isodecanoic acidester cross-linked polymer sodium, triethanolamine, (daily) essence and the balance water. The spray has the advantages that the carrying is convenient; the spray is mild and does not contain conventional preservatives; and the spray can help the skin actively resist the harm to the skin caused by adverse environment, achieves the effects of water replenishing, moisture preservation, deep restoration and senility delaying, and is suitable for outdoor traveling and sports doing people groups to use.