55 results about "Metabolism proteins" patented technology

The present invention provides, for example, DNA encoding a herbicide metabolizing protein selected from the protein group below. Such DNA may, for example, be employed to produce herbicidally resistant plants. <protein group>a protein comprising the amino acid sequence shown in SEQ ID NO: 1, 2, 3, 108, 159, 160, 136, 137, 138, 215, 216, 217, 218, 219, 220, 221, 222, 223 or 224,

a protein having an ability to convert in the presence of an electron transport system containing an electron donor, a compound of formula (II):

to a compound of formula (III):

and comprising an amino acid sequence having at least 80% sequence identity with an amino acid sequence shown in any one of SEQ ID NO: 1, 2, 3, 108, 159, 136, 137, 138, 215, 216, 217, 218, 219, 220, 221, 222, 223 or 224 or an amino acid sequence having at least 90% sequence identity with an amino acid sequence shown in any one of SEQ ID NO: 160, 215, 216, 218, 222 or 224.

The invention discloses a Chinese herbal medicinal additive for preparing a pigling feed and belongs to the field of Chinese herbal medicines. The formula of the Chinese herbal medicinal additive is designed according to physiological characteristics of piglings. The Chinese herbal medicinal additive is prepared by decoction of raw materials including Radix Astragali, fleece-flower root, acanthopanax, Radix Codonopsis, corydalis tuber, honeysuckle flower, radix bupleuri, Sophora flavescens, safflower, dryopteris crasirhitom nakai, orange peel, medicated leaven, haw, plantain herb and phellodendron. The Chinese herbal medicinal additive contains a plurality of effective active components, can be used to promote synthesis of ferrohemoglobin and serum protein of piglings, resist anaemia and improve protein metabolism, raise utilization efficiency of nutrients and content of cholesterol in serum and enhance regeneration capacity of body, and also has a good effect of promoting metabolism and the like of piglings.

The invention provides DNAs encoding a weed controller metabolism protein selected from the following groups, which are useful in, for example, constructing a weed controller-tolerant plant. Proteins having an amino acid sequence represented by SEQ ID NO: 1, 2, 3, 108, 159, 160, 136, 137, 138, 215, 216, 217, 218, 219, 220, 221, 222, 223 or 224. Proteins having an amino acid sequence showing a sequence identity of 80% or more with one of the amino acid sequences represented by SEQ ID NOS: 1, 2, 3, 108, 159, 136, 137, 138, 215, 216, 217, 218, 219, 220, 221, 222, 223 or 224, or an amino acid sequence showing a sequence identity of 90% or more with one of the amino acid sequences represented by SEQ ID NO: 160, 215, 216, 218, 222 and 224, and being capable of converting the compound represented by the following formula II into the compound represented by the following formula III in the presence of an electron transfer system from an electron donor.

The invention relates to a low-energy-diet (LED) having effect on the basal metabolic rate, the protein metabolism and/or the energy expenditure, such as a low-energy-diet comprising Carbohydrate: 70-120 g, Protein: 50-80 g, Fat: 5-20 g, including medium chain triglycerides, and Iron: 20-30 mg/d, wherein the carbohydrate source and/or the fat source may increase the energy expenditure.

The invention relates to a black soya bean powder nutritious instant noodle containing black soya bean anthocyanidin and preparation method thereof. which is characterized in that: the formula comprises the materials of following weight parts: wherein, the main material comprises 20-30 black soya bean powder, 25-35 corn flour, 10-20 corn starch and 20-35 wheat flour; and the auxiliary material comprises: 1-3 black soya bean coat powder, 1.7 salt, 0.05 composite phosphate, 0.35-0.4 sodium carbonate, 0.1-0.15 potash, 0.17-0.18 sodium polyacrylat, 0.2-0.25 sucrose ester and 0.1-0.2 stearyl sodium lactate. The product achieves the advantages of slip mouthfeel, socking durable, boilable and short rehydrating time; the invention increases protein content, meets the daily protein metabolism needof human body basically and improves the nutritive value of traditional instant pasta in substance; and is a real instant, nutritious and health food for containing rich anthocyanidin.

The invention relates to a formulated foodstuff with special medical purposes for patients with hyperuricemia and gout and provides a granule or powder solid beverage formed by mixing both medicinal and edible plants and extract thereof and a nutrient supplement. The granule or powder solid beverage contains submicron powder of green papaya, banana peel extract, green tea extract, sweet potato vine extract, kudzu vine root extract, Poria cocos extract, lotus leaf extract, cape jasmine extract, haw extract, licorice extract, stevia rebaudiana extract, xylo oligosaccharide, dipotassium hydrogen phosphate, sodium bicarbonate, vitamin C and nicotinamide. The granule or powder solid beverage provided by the invention is mainly directed at the characteristic of purine metabolism disorders of patients with hyperuricemia and gout, improves the complex process of biochemical metabolism like protein metabolism, purine metabolism and lipid metabolism in the bodies of patients with hyperuricemia and gout in virtue of special physiological active substances and targeted micronutrients included in the granule or powder solid beverage, indirectly inhibits synthesis of uric acid, promotes acid discharging and maintains nutrition functions like acid-base balance of the body.

The invention belongs to the technical field of research and development of medical products and relates to a preparation method and application of a composite Chinese magnoliavine fruit preparation. The method comprises the following steps of: selecting 6 to 9 grams of high-quality Chinese magnoliavine fruit, 6 to 9 grams of boschniakia rossica, 3 to 6 grams of eucommia bark, 3 to 6 grams of acanthopanax root, 3 to 6 grams of ginseng, 3 to 6 grams of lucid ganoderma, 3 to 6 grams of astragalus, 3 to 6 grams of mushroom, 2 to 4 grams of Indian buead, 2 to 4 grams of agaric, 2 to 4 grams of yam, 2 to 4 grams of hawthorn and 2 to 4 grams of Chinese date; washing; performing microwave drying; smashing into 50-mesh powder; adding water for boiling and extracting for three times; combining extracting solution; filtering to obtain filtrate; condensing the filtrate into extract; uniformly mixing the extract, agar and starch in the ratio of 4:1:16; and pelletizing by using a 10-mesh sieve; drying; sieving by using a 14-mesh sieve so as to obtain the composite Chinese magnoliavine fruit preparation. A product has the effects of promoting the liver function and protein metabolism of fancy carp, and is beneficial to industrial production.

The invention discloses 214 novel phosphorylation sites identified in signal transduction proteins and pathways underlying human carcinoma, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose. Among the phosphorylation sites identified are sites occurring in the following protein types: Adaptor/Scaffold proteins, Cytoskeleton proteins, GTP Signaling proteins, Kinases, Metabolism proteins, Phosphatases/Phospho-diesterases/Proteases, Receptor proteins, RNA Processing proteins, Transcription proteins, Translation proteins, Transporter proteins, and Ubitquitin proteins, as well as other protein types.

The invention belongs to the technical field of medical product research and development, and relates to a preparation method and application of a compound white paeony root preparation. The preparation method comprises the following steps of: selecting and washing 6 to 9 g of high-quality white paeony root, 4 to 6 g of lucid ganoderma, 4 to 6 g of astragalus mongholicus, 4 to 6 g of ginseng, 4 to 6 g of honeysuckle, 4 to 6 g of andrographis, 4 to 6 g of baical skullcap root, 4 to 6 g of acorus calamus, 4 to 6 g of isatis root, 2 to 4 g of rhubarb, 2 to 4 g of phellodendron, 2 to 4 g of dandelion, 2 to 4 g of sophora flavescens, 2 to 4 g of garlic and 2 to 4 g of liquorice root; drying by using microwave; crushing into 50-mesh powder; adding water, boiling and extracting for 3 times; combining extracting solution; filtering to obtain a filtrate; concentrating the filtrate into an extractum; mixing the extractum and starch in a ratio of 1:4; granulating by using a 10-mesh sieve; and drying and screening by using a 14-mesh sieve to obtain the compound white paeony root preparation. The product has the effects of promoting the liver function and the protein metabolism of fancy carps. The product contributes to industrial production.

A sugarless strengthening element chickpea powder relates to an accessory food made of chickpea and used for curing diabetes and other diseases. The chickpea is peeled, grinded into thick liquid, added with maltodextrin and accessories containing chromium, concentrated, sprayed and dried, and then the chick pea powder is made. The chickpea powder is applied to children who are growing and the elderly. The chickpea not only supplements chromium easily lacked in the growing phase and in old age but also supplements finer protein substrate. Many experiments find that chromium plays an obvious role in promoting growth and development and in enhancing protein metabolism of the children who do a large amount of sports in the growing phase, thus improving the effect of light weight. As for the elderly, the chickpea supplements chromium easily lacked when supplementing calcium and protein at the same time, and also provides a certain amount of medium-chain fatty acid which does not accumulates in the body, thus effectively preventing and regulating diabetes, hyperlipidemia, atherosclerosis, osteoporosis, low immunity and other diseases.

The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and/or vitamin B12 and, optionally, agents that impact heme protein metabolism.

The invention discloses a gene chip used for researching the action of an AD (Alzheimer Disease)-controlling medicament. An oligonucleotide gene probe array is fixed on the chip, wherein the oligonucleotide is an important biomolecule gene closely related to the occurrence and development process of the AD and relates to pathophysiological molecules, such as familial AD genes and susceptibility genes, amyloidosis, microtubule and cytoskeleton recombination, cynapse function, neurotransmission and ion channel, nerve regeneration, immunoregulation, immune response, signal transduction, chondriosome, protein metabolism, and the like. The chip of the invention can be used for researching pharmacological actions and action mechanisms of the AD-preventing and treating medicament containing a chemical medicament, a biotech drug, a single traditional Chinese medicine, a traditional Chinese medicine compound and an extract thereof, researching the sifting, the prescription, and the like of the AD-controlling medicament and researching the AD pathogenesis and carrying out auxiliary and differential diagnosis on a clinical case. The gene chip overcomes the defect of researching a multifactorial disease medicament by utilizing the method of a single target and has favorable application prospect.

The present invention discloses a piglet composite premix composition. The composition comprises the following raw materials, wherein the raw materials comprise, by mass: 0.04-0.05 parts of glycine zinc, 0.1-0.2 parts of ferrous fumarate, 0.01-0.015 parts of yeast selenium, 0.1-0.15 parts of ethoxyquin, 0.1-0.3 parts of yeast chromium, 0.05-0.1 parts of lysine zinc, 10-25 parts of calcium hydrogen phosphate, 40-60 parts of zeolite powder, and 10-20 parts of calcium carbonate. The 1 Kg of the prepared piglet composite premix composition further comprises: 240-300 IU of VE, 800-900 mg of VB2, 500-600 mg of VB12, and 350-400 mg of VB6. With adopting the piglet composite premix composition of the present invention in the feed ration, the appetite of the piglets can be enhanced, and the growthdevelopment and the tissue regeneration of the body can be promoted; with accelerating the glucose utilization in the body, the protein metabolism and the growth development are promoted so as to increase the feed intake, and completely digest, absorb and utilize the nutrient substances in the feed; with participating in the immune function, the immune mechanism is enhanced, the resistance is improved, and the external stress can be effectively resisted.

The invention discloses a medicine for resisting altitude stress and production equipment, and relates to the field of medicine for resisting altitude stress. The medicine for resisting altitude stress is prepared from the following components in parts by weight: 10-20 parts of rhodiola crenulata powder, 5-10 parts of dried ginger powder, 8-10 parts of tomato powder, 5-10 parts of soybean powder, 5-10 parts of brown powdered sugar, 10-15 parts of plum powder, 2-5 parts of coenzyme Q10, 1-2 parts of selenium, 3-5 parts of a vitamin mixture and 2-4 parts of amineral matter mixture. Selenium can activate main antioxidant enzyme-glutathione anti-peroxidase in cells, soybean meal and pea meal can increase protein intake, when people enter plateau areas, protein metabolism of organisms is enhanced, sufficient high-quality protein must be eaten, and by matching with the rhodiola crenulata powder for medicine preparation, the effect of the medicine for resisting altitude stress is improved; and meanwhile, the plum powder and the brown powdered sugar are added, the sweet taste is increased through the brown powdered sugar, the sour taste is increased through the plum powder, the taste of the medicine can be adjusted, the medicine is convenient to take, and large-scale application and popularization are facilitated.

The invention relates to the field of food, in particular to an energy bar, a preparation method thereof and application of the energy bar in preparation of muscle injury resistant products. The energy bar is prepared from the following raw materials: cocoa butter replacer dark chocolate, isomaltooligosaccharide, highland barley protein, soybean protein, whey protein, quinoa, peach kernel, medium-chain triglyceride, casein, whole milk powder, glycerol and edible oil. The isomaltooligosacharide, MCT and other raw materials in the energy bar provided by the invention can ensure the rapid energysupply and slow energy supply effects of the product, and besides, proteins from different sources contained in the energy bar cooperate with each other, so that the protein metabolism requirements atdifferent exercise stages can be met as much as possible, muscle tissues of exercisers are repaired, and therefore, the energy bar disclosed by the invention can also be used for enhancing the satiety of the product.

The invention discloses high-protein black chocolate sauce. The high-protein black chocolate sauce comprises the following raw materials in parts by weight of 164-200 parts of medium-chain triglyceride, 180-240 parts of whey protein isolate powder, 40-70 parts of erythritol, 18-27 parts of low-fat cocoa powder, 6-12 parts of citrus fibers, 2-3 parts of phospholipid and 1-3 parts of bacillus coagulans. A preparation method of the high-protein black chocolate sauce comprises the following steps of taking half of the medium-chain triglyceride and the citrus fibers, performing uniform stirring byusing a high-speed shearing machine, adding the residual medium-chain triglyceride and the erythritol into an electric heating sauce boiling jacketed kettle, performing stirring, then sequentially adding the low-fat cocoa powder, the whey protein isolate powder, the phospholipid and the bacillus coagulans, performing uniform stirring, and performing homogenization for three times in a homogenizerto obtain the finished high-protein black chocolate sauce. The black chocolate sauce has the advantages that the black chocolate sauce is free of fat and beneficial to reduction of fat intake of users, and the whey protein powder is easy to absorb; digestion is promoted, immunity is enhanced and health of protein metabolism is promoted; and the melting point of the black chocolate sauce can be increased to 40 DEG C, so that modeling of desserts such as cakes is facilitated.

The invention discloses a traditional Chinese medicine preparation for treating liver cirrhosis. The traditional Chinese medicine preparation is prepared from the following raw materials: radix bupleuri, white peony root, liquorice, fructus aurantii, pericarpium citri reticulatae, rhizoma cyperi, ligusticum wallichii, rhizoma corydalis, szechwan Chinaberry fruit, fingered citron, costustoot, caulis perllae, arrowroot, cortex albiziae, salviae miltiorrhizae, sandalwood, fructus amomi, flos carthami, ucid ganoderma, myrrh, mint and dried radix rehmanniae. After patients take the traditional Chinese medicine preparation disclosed by the invention, blood meridians of whole bodies are dredged; abdominal distension disappears; the urine volume and exhaust are increased; food intake is increased; after most of patients take the traditional Chinese medicine preparation for about two months, the liver function can be obviously improved; and ascites symptoms disappear. A clinical research proves that the efficacies of tonifying the spleen, promoting blood circulation to remove blood stasis, softening the liver and the like are scientifically combined together on the basis of experience of the ancients in the treatment scheme; and the traditional Chinese medicine preparation has the effects of improving clinical symptoms and signs, protecting the liver, lowering enzyme, adjusting protein metabolism of the liver and resisting liver fibrosis.

The invention discloses a traditional Chinese medicine composition applied to preparing medicines for curing diabetes cardiomyopathy. Tests prove that the pharmaceutical composition can enhance the activity of suckling mouse cardiac muscle cells in vitro culture; by promoting the expression of mRNA of superoxide dismutase (SOD2), free radicals are eliminated and high-glucose-induced myocardial cell injury is prevented by restraining oxidative stress; simultaneously, the medicinal composition can improve myocardial lesions of a diabetes rat model and restrain cardiac muscle cell apoptosis; gene chip test results show that the medicinal composition plays the roles of curing the diabetes cardiomyopathy in the aspects of correcting sugar and protein metabolism, enhancing antioxidant capacity, inhibiting cell apoptosis and the like; and the experimental results prompt that the medicinal composition can protect the cardiac muscle of a patient and cure the diabetes cardiomyopathy.

The identification of 101 genes upregulated or differentially expressed by mature human oocytes is provided herein. These genes and the corresponding gene products will facilitate a greater understanding of oogenesis, folliculogenesis, fertilization, and embryonic development. In addition these genes and the corresponding gene products can be used to effect dedifferentiation and/or transdifferentiation of desired somatic cells. The resultant dedifferentiated cells and somatic cells derived therefrom can be used in cell therapies such as in the treatment of cancer, autoimmunity, and other diseases wherein specific types of cells such as hematopoietic cells may be depleted because of the underlying disease or the treatment of the disease.

Also, a core group of 66 transcripts was identified by intersecting significantly up-regulated genes of the human oocyte with those from the mouse oocyte and from human and mouse embryonic stem cells. Within the up-regulated probe sets, the top overrepresented categories were related to RNA and protein metabolism, followed by DNA metabolism and chromatin modification. This invention therefore provides a comprehensive expression baseline of genes expressed in in vivo matured human oocytes. Further understanding of the biological role of these genes will also expand knowledge on meiotic cell cycle, fertilization, chromatin remodeling, lineage commitment, pluripotency, tissue regeneration, and morphogenesis.

The invention discloses a high-yield leucine p-nitroanilide production lactobacillus helveticus strain and application thereof and belongs to the field of microbial technology. The high-yield leucinep-nitroanilide production lactobacillus helveticus strain, namely lactobacillus helveticus CCFM1035, has the advantages of being high in growth and production speed as well as high in yield of leucinep-nitroanilide (Lys-pNA), and can effectively enhance the protein metabolism of fermented foods, reduce bitter taste of the fermented foods and improve the flavor of the fermented foods, thereby highin application significance to prepared foods such as acidified milk, acidified milk beverages, cheese, Koumiss, sour cream, cookies, vinegar and soybean sauce.

The invention discloses a method for preparing hotpot condiment grease rich in medium and long carbon chain triglyceride by an enzyme method, which comprises the following steps: taking medium and long carbon chain triglyceride as raw materials, adding expanded lipase into a solvent system, and reacting to obtain the hotpot condiment grease. Vegetable oil is selected as a raw material, the price of the vegetable oil is lower than that of beef tallow, the vegetable oil does not contain cholesterol and trans-fatty acid and is healthier than the beef tallow, and the obtained product is rich in medium and long carbon chain triglyceride and has positive effects in the aspects of weakening protein metabolism, promoting nitrogen balance, enhancing the immune function, reducing cancer risks and the like.

The invention relates to a drug made from alidase, glucocorticoids, triamcinoloni acetonidi acetas, and aromatic compound. The invention can affect protein metabolism, interfere fiber increment, etc. And it comprises 2 deals alidase, 40 deals glucocorticoids, 333 deals aromatic compound, and 2000-3000 deals agent xo; the agent xo can be 200 deals of hydrocolloid, 2000 deals of glycerol monostearate, 2000 deals of plyvinyl formal, 3000 deals polyisobutene (MML.100), 2000 deals glycerin, 2000 deals hydroxyethyl methacrylate (P-HEMA), 2000 deals propanediol, 2000 deals soybean phosphatides, or 2000 deals normal saline.

The invention belongs to the technical field of research and development of medical products. The invention relates to a preparation method and application of a compound radix bupleuri preparation. The preparation method comprises the following steps: selecting 4-6g of high-quality radix bupleuri, 4-6g of medlar, 4-6g of spirulina, 4-6g of mushroom, 4-6g of kelp, 4-6g of cordate houttuyniae, 4-6g of ginseng, 2-3g of star anise, 2-3g of ginger, 2-3g of garlic, 2-3g of hawthorn, 2-3g of Chinese date and 9-12g of shrimp meal, washing, carrying out microwave drying, and grinding into 50-mesh powder; adding water to the powder, boiling to extract three times, merging the extracting solutions, and filtering to obtain the filtrate; and concentrating the filtrate into extract, uniformly mixing the extract and starch at a ratio of 1:4, granulating with a 10-mesh sieve, drying, and then sieving with a 14-mesh sieve, thus obtaining the compound radix bupleuri preparation. The product has the function of promoting liver functions and protein metabolism of golden carps and is beneficial to industrial production.

The invention relates to a synthetic method of stable isotope deuterium-labeled alpha-amino acid. According to the method, one or more deuterium-labeled halides are taken as labeled precursors and subjected to a reaction with phthalimide dimethyl malonate sodium salt, one or more deuterium-substituted phthalimide dimethyl malonate is obtained, and after hydrolysis, stable isotope deuterium-labeledalpha-amino acid is obtained. Compared with the prior art, the synthetic method is simple, safe and reliable, chemical purity of a product after simple separation and purification reaches 99% or higher, isotope abundance is 99% or higher, and the method can be applied to fields of protein metabolism tracing, food safety testing and the like.