2 results about "Poly-L-lactic-polyglycolic acid" patented technology

This invention relates to a strength-modified block copolymer based on polylactic acid (PLA) / polyglycolic acid (PEG), its preparation method, and its application, belonging to the field of block copolymer technology. It solves the technical problem in the prior art where PLA or PEG has poor compatibility with PB / AT, making it difficult for both to fully utilize their respective advantages. The preparation method of this invention involves first uniformly mixing phthalic acid, adipic acid, an aliphatic diol, a polyol with ≥3 hydroxyl groups, and an organometallic ester, then heating and reacting the mixture under reduced pressure to remove water and excess polyol, yielding an alcohol-modified poly(terephthalic acid-adipic acid-diol ester). Then, molten dehydrated lactone monomer, a catalyst, and solvent oil are added, and the mixture is heated and reacted to obtain the strength-modified block copolymer based on PLA / PEG. This block copolymer exhibits good toughness, ductility, elongation at break, heat resistance, and excellent impact performance, and can be used as a temporary plugging agent.

A method of repairing a bone fracture in a patient specifically configured for repairing critical-sized segmental bone fractures by utilizing patient-specific three-dimensional printed implants. The method includes imaging the bone fracture in need of repair; generating a fracture model of the bone fracture based on the imaging; forming a model of a bone repair implant based on the fracture model; manufacturing the bone repair implant using an additive manufacturing method based on the model; and surgically implanting the bone repair implant adjacent to the bone fracture in the patient. The bone repair implant includes a bone scaffold, a support plate, and a screw. The bone repair implant is constructed of a biodegradable material such as polylactic acid, polyglycolic acid, or poly lactic acid glycolic acid.