30results about How to "Process pollution is small" patented technology

The invention provides a method for preparing tea seed oil in a low-temperature cold pressing manner. The method comprises the following steps of cleaning tea seeds, removing shells and separating, milling oil at normal temperature, washing in water at low temperature, dehydrating under negative pressure, refining at low temperature, filtering for many times, winterizing and dewaxing. The method for preparing the tea seed oil in the low-temperature cold pressing manner, provided by the invention, has the advantages of simple process, low energy consumption and high oil yield; and the prepared tea seed oil has shallow color, high quality and comprehensive nutrition, and also keeps the original flavor of tea oil.

Provided is a cellulose ester film including a polycondensed ester which is obtained from a mixture containing an aromatic dicarboxylic acid, an aliphatic dicarboxylic acid, an aliphatic diol having an average carbon atom number of from 2.0 to 3.0 and a monocarboxylic acid, and both terminals of which are a monocarboxylic acid ester derivative.

The invention relates to a method for extracting high-purity scutellarin from breviscapin. The method comprises the following steps: the breviscapin raw material is extracted by using organic solvent, the filtrate is added with clarifying agent for coagulation and clarifying, the coagulated and clarified filtrate is absorbed by macroporous absorbent resin and is eluted with water, the water eluent is concentrated through a reverse osmosis membrane or nanofiltration membrane, the concentrated solution is added with the organic solvent for standing and precipitation, the sediment is filtered and collected, the aqueous solution of the organic solvent is added and stirred to be suspendible, and after standing a night, the sediment is filtered, collected and washed to be near-neutral with water to obtain the high-purity scutellarin after drying. The alkali is not used in the entire process, the clarifier is used for removing the water insoluble matter, the impurity removal is carried out by using the macroporous absorbent resin, the concentration is carried out by using the reverse osmosis membrane or the nanofiltration membrane, the scutellarin plant salt is prevented from being heated and degraded in water, the content of the prepared scutellarin can reach above 97 percent, the quality is stable, the process is simple and the pollution is little.

The invention relates to a preparation method of 6-bromine-2-pyridine methyl formate. The preparation method comprises the step of catalyzing esterification reaction of 6-bromine-2-pyridine carboxylic acid by taking p-toluenesulfonic acid as a catalyst, to be specific, heating and fluxing absolute methanol, the 6-bromine-2-pyridine carboxylic acid and the p-toluenesulfonic acid for 2-8 hours under stirring, cooling to a room temperature after reaction is ended, rotary drying a reaction system, dissolving solids in an organic solvent, washing, drying, filtering, concentrating, recrystallizing a concentrated product by a mixed solvent to obtain the 6-bromine-2-pyridine methyl formate, wherein a preferable molar ratio of the 6-bromine-2-pyridine carboxylic acid and the p-toluenesulfonic acid is 1: (0.1-0.16). According to one embodiment of the invention, the 6-bromine-2-pyridine carboxylic acid is obtained through diazotization, bromination and oxidation of 6-amino-2-methylpyridine. The preparation method is few in side reaction and simple in aftertreatment and is suitable for industrial production; and the product is easy to separate and has high yield, high purity and good quality.

The invention discloses a process for synthesizing chromium picolinate. The process uses 2-pyridinecarbonitrile and chromic salt as reactants to generate the chromium picolinate by one-step hydro-thermal synthesis reaction at a temperature of between 80 and 200 DEG C under 2 to 3 standard atmospheric pressure. The process has simple operation, easily realizes mass production, and greatly reduces the manufacturing cost; moreover, the whole process is a green production with low environmental pollution.

The invention relates to a preparation process of high-purity 4-chloro-2-pyridinecarboxylate hydrochloride, which comprises the following steps of reacting 2-methyl-4-nitropyridine-N-oxide taken as a starting raw material with hydrochloric acid to obtain 4-chloro-2-methyl-pyridine-N-oxide; then dripping phosphorus trichloride into an organic solvent, carrying out reaction for generating 4-chloro-2-methylpyridine, further adding potassium permanganate into water for carrying out oxidation reaction, thus obtaining 4-chloro-2-picolinate; and mixing the 4-chloro-2-picolinate with the catalytic amount of DMF (dimethyfumarate), dripping thionyl chloride, and finally carrying out esterification reaction with methanol so as to obtain the 4-chloro-2-pyridinecarboxylate hydrochloride. The total yield can be up to 36.8%, and the purity can be 99.8% according to the HPLC (high performance liquid chromatography) detection. The process has the advantages of being rich in raw material resources, small in whole process pollution, conductive to controlling three wastes and easy for realizing industrial production.

The invention relates to a preparation method of amorphous dasatinib, wherein the preparation method includes the steps: dissolving raw materials of various crystal types of dasatinib in an anhydrous organic solvent at the temperature of 60-100 DEG C, adding a cosolvent for helping dissolution, and thus obtaining a fully-dissolved dasatinib solution; carrying out spray drying on the dasatinib solution, carrying out cyclone isolation, and rapidly precipitating to obtain a dasatinib solid powder; drying the dasatinib solid powder under reduced pressure, removing the solvent, and thus obtaining the dasatinib amorphous product. Through testing, the prepared amorphous dasatinib has the moisture content generally less than 2%, and is nearly anhydrous dasatinib. The method is suitable for converting various crystal types of dasatinib into the dasatinib amorphous product having the residual solvent consistent with Chinese pharmacopoeia, and the preparation yield reaches up to more than 99%. Moreover, the method has the advantages of simple operation, less operation steps, less using solvent, small process pollution, low cost and the like, and is suitable for large-scale industrialized production.

The invention provides an ammonia recovery system for wastewater with high content of ammonia and nitrogen. The system comprises the following process steps the wastewater with high content of ammoniaand nitrogen is introduced into a stripping tower for stripping to generate high-concentration ammonia gas, the ammonia gas with moisture is introduced into a water washing tower, after water washingand impurity removal are conducted through the water washing tower, the moisture in the ammonia gas is removed through a mist eliminator, a pressure regulating tube and a filter in sequence, then theammonia gas is conveyed to an ammonia compressor for compression and pressurization, and finally the ammonia gas is condensed by a condenser to obtain liquid ammonia; liquid ammonia flows into an ammonia reflux tank serving as a transfer station and partially flows back into the water washing tower for secondary recycling, and other liquid ammonia is conveyed to an ammonia storage tank to obtainpure liquid ammonia. Through reasonable process improvement and parameter setting, the efficiency of recovering the high ammonia nitrogen wastewater is effectively improved, the purity of recovered liquid ammonia is high, the problems of secondary pollution and high energy consumption during ammonia recycling are solved, the ammonia recovery cost is reduced, and the environmental pollution is reduced.

The present invention discloses a preparation method of 1,1-diphenyl ethane. The preparation method comprises the following steps: using ionic liquid as a catalyst, and reacting benzene with 1,1-dichloroethane for 3-6 hours at 0-80 DEG C; and synthesizing 1,1-diphenyl ethane, wherein the precursor compound of the ionic catalyst is selected from pyridinium halide, imidazolium halide, trialkylamine halide and quaternary ammonium salt. The preparation method has the beneficial effects that the synthesis process is simple, the yield is high, and the process pollution is low. The catalytic activity of the ionic liquid used in the preparation method disclosed by the present invention is high without adding any other auxiliary agent or organic agent; and the used ionic liquid is free of pollution to the environment, and after the reaction, the ionic liquid can be separated and recovered conveniently and can be reused, so that the environmentally-friendly catalytic process is realized.

The invention relates to a preparation method of 3,4-substituted thiobenzamide. The 3,4-substituted thiobenzamide prepared by the method can be used to synthesis of febuxostat, a novel drug for treating gout.

The invention relates to a preparation method of 2-bromo-N, N-dimethylaniline, which is characterized in that mesitylene is used as a reaction solvent to participate in methylation reaction of trimethyl phosphate and o-bromaniline to prepare the 2-bromo-N, N-dimethylaniline. The use of bromine is avoided, and the whole process is small in pollution; the side reaction is few, the post-treatment is simple, the product is easy to separate, and the process operation is simple; meanwhile, compared with a bromination method under the condition of single bromine in the prior art, the yield is increased by 3 times, the yield is high, the product purity is high, the cost is lower, the reaction condition is mild, the controllability is high, the safety is high, and the method is particularly suitable for large-scale industrial production.