The invention provides a method for measuring the content of wood preservatives of wooden products for children. The method comprises the following steps: crushing a sample to be measured, performing ultrasonic extraction by using methanol, filtering, adding an interior label working solution into the filtrate, centrifuging, filtering the supernate by using a filtering membrane, and performing spin-steaming concentration; and adding a potassium carbonate solution into the concentrated liquid, shaking uniformly, adding acetic anhydride, performing derivatization, oscillating while deflating and allowing the derivatized concentrated liquid to pass through an Oasis hydrophile lipophile balance (HLB) solid phase extraction column; sequentially leaching by using deionized water, pumping all the water by using a vacuum pump and eluting by using ethyl acetate to obtain eluent; adding a proper amount of anhydrous sodium sulfate into the eluent and drying; and performing vortical oscillation and measuring by a gas chromatography-tandem mass spectrum method. The invention establishes the method for measuring the content of 10 wood preservatives of the wooden products for children based on solid phase extraction-gas chromatography-tandem mass spectrum, which has excellent selectivity and sensitivity on detection of target objects of wood samples with complex matrix.