30results about How to "Strong slow release" patented technology

The invention relates to a method for preparing monodisperse mesoporous bioactive glass microspheres through a template method, belonging to the field of biomedical materials. A silicon source, a phosphorus source, a calcium source, an iron source, an alkali metal or alkaline-earth metal source is adopted as a raw material, a triblock copolymer or alkyl quaternary ammonium salt type cation is taken as a surfactant, and an in-situ sol-gel method is performed in a three-dimensional ordered macroporous polymer or a carbon template to synthesize the ordered mesoporous bioactive glass microspheres. The bioactive glass microspheres prepared according to the invention have the characteristics of good biocompatibility, biodegradability, ordered mesoporous structure, higher specific surface area, magnetism, monodispersibility of particles, environmental stability and the like; and in comparison with various medicament delivery carrier materials which are extensively researched currently, the bioactive glass microspheres have more comprehensive advantages and further have broad application prospects as novel medicament controlled release carrier materials.

The invention provides sericin-alginate compounded hydrogel and a preparation method thereof. The method comprises the steps that 1, silkworm cocoons of bombyx mori silk fibroin deletion type mutation varieties are weighed, extraction is carried out with LiBr or LiCl water solution, dialysis and purification are carried out, concentration is carried out, and a nondegradable sericin water solution with the mass percentage concentration being 1.5% to 10% is obtained; 2, an alginate water solution with the mass percentage concentration being 0.1% to 10% is prepared; 3, in the presence of a cross-linking agent, the sericin water solution and the alginate water solution are mixed in the proportion of (100-0.01):1, and the sericin-alginate compounded hydrogel is prepared, wherein the cross-linking agent comprises an ionic cross-linking agent and / or a covalent cross-linking agent. According to the scheme, the sericin-alginate compounded hydrogel of an interpenetrating polymer network can be obtained, the obtained compounded hydrogel has excellent fluorescence characteristics, deformation memorability and elasticity modulus adjustability and further has good biocompatibility and cell adhesion, and survival, proliferation and migration can be supported for a long time.

The invention provides a chitosan-sericin composite biological scaffold as well as a preparation method and application thereof. The preparation method comprises the following steps: dissolving chitosan by taking an acetic acid solution as a solvent to obtain a chitosan solution; preparing a sericin aqueous solution from the cocoon of bombyx mori of the fibroin-deleted mutant variety; uniformly mixing the chitosan solution and the sericin aqueous solution and pouring into a mould; adding a crosslinking agent for moulding to obtain a chitosan-sericin composite hydrogel; and freeze-drying the chitosan-sericin hydrogel to obtain the chitosan-sericin composite biological scaffold. The invention also provides a composite biological scaffold carrying a nerve growth factor NGF for peripheral nerve entrapment treatment. The composite biological scaffold provided by the invention has good biocompatibility and relatively high porosity and degradability, and the degradation product also has a neurotropic effect; the composite scaffold also has antibacterial and anti-adhesion functions and the like; and compared with the traditional way of relieving sciatic nerve compression simply by operation, the composite biological scaffold provided by the invention can effectively promote the repairing of peripheral nerve entrapment injury.

The invention relates to the field of compound fertilizers, and particularly relates to a slow-release compound fertilizer containing natural worm-expelling components. The fertilizer is prepared from the following raw materials in parts by weight: 10-15 parts of kieselguhr of 1250-2000 meshes, 10-12 parts of potassium sorbate, 16-19 parts of ammonium dihydrogen phosphate, 4-5 parts of magnesium chloride, 10-12 parts of sodium pyrophosphate, 22-23 parts of well-rotted farmyard manure, 6-8 parts of dried tempeh fine powder, 4-6 parts of formosan lattuce herb leaf and stem, 5-6 parts of Tephrosia purpurea stem and leaf, 4-5 parts of burdock dreg powder, 1-3 parts of starch aluminum octenylsuccinate, 1-2 parts of potassium persulfate, 10-12 parts of acrylamide, 1-2 parts of negative ion powder, 2-4 parts of medical stone powder, 6-8 parts of polymeric ferric silicate sulfate and 4-5 parts of assistant. According to the invention, the compound fertilizer formula has wide raw material sources and multiple nutrients; slurry of the formosan lattuce herb leaf and stem and the Tephrosia purpurea stem and leaf contains natural worm-expelling components, so that worms and ants can be prevented from nibbling the fertilizer; and by technically using the kieselguhr and the slow-release coating agent containing the negative ion powder, the nutrients are doubly coated, so that the nutrients are less prone to loss, and the fertilizer efficiency can last longer. In practical application, the compound fertilizer can obviously improve the yield and quality of crops and increase economic benefits.

The invention discloses a bacterial cellulose stable Pickering double emulsion as well as a preparation method thereof. The method comprises the following steps: S1, dissolving a thickening agent intoa buffering solution, adding a cross-linking agent divalent salt ions to form gel, and obtaining gel-shaped inner water phase W1; S2, dissolving the oil-soluble emulsifier in edible oil to form an oil phase O, mixing the oil phase O and the inner water phase W1 in a high-speed cutting manner, and obtaining primary emulsion W1 / O; and S3, adopting suspension of bacterial cellulose colloid particlesas an outer water phase W2, adding the outer water phase W2 into the primary emulsion W1 / O, cutting mixing at a medium speed, and obtaining W1 / O / W2 Pickering double emulsion. Raw materials for the Pickering double emulsion are food-grade, the safety is high, the storage stability is good, the sustained release performance is high, the development field of the food-grade Pickering emulsion is enlarged, and the application potential in the food industry is vast.

The invention provides particles and tablets of a high-strength urea formaldehyde slow release fertilizer produced through dry-process granulation. The urea formaldehyde slow release fertilizer is prepared from urea formaldehyde, nitrogenous fertilizer, phosphatic fertilizer, potassic fertilizer and packing through pressing. In addition, the invention also provides a preparation method, an application and the like of the urea formaldehyde slow release fertilizer.

The invention discloses a carbon-based slow-release fertilizer with high slow release capability. The carbon-based slow-release fertilizer is prepared from raw materials in parts by weight as follows: 15-18 parts of rice straw, 4-5 parts of a modified cassava starch solution, 1-3 parts of ferrous sulfate, 4-6 parts of ammonium nitrate, 1-2 parts of sodium carboxymethylcellulose, 12-16 parts of guar gum powder, 25-26 parts of feather meal, 3-5 parts of attapulgite, 3-6 parts of humic acid raw powder and 33-37 parts of bagasse. The carbon-based slow-release fertilizer can adsorb and stabilize nutrients in the fertilizer by the aid of porosity and large specific surface area; meanwhile, the carbon-based slow-release fertilizer has excellent biological chemistry stability, can remarkably reduce loss of soil nitrogen, maintains balance of soil ecosystem and has remarkable slow release capability, the use amount of the fertilizer can be reduced after application, the utilization rate of nutrients is increased, and the yield of crops and incomes are increased.

The invention relates to a preparation method of a chitosan multilayer coated wheat slow-release fertilizer. The preparation method comprises the following steps: uniformly mixing a fertilizer and auxiliary materials, adding into an acetic acid solution of chitosan, stirring until complete dissolution, and adding into a glutaraldehyde mixed solution of sodium alginate in a dropwise manner to formparticles with an inner coating layer; humidifying the particles with the inner coating layer, adding a chitosan outer coating material, uniformly coating the outer layer of the particles with the inner coating layer with the chitosan outer coating material to obtain particles with the outer coating layer, and finally drying, polishing and sieving to obtain the multilayer coated slow-release fertilizer. The multilayer coated slow release fertilizer prepared by the invention has slow / controlled release function, stably provides nutrition elements in a certain period of crop growth, completely provides fertilizer efficiency, reduces fertilizer loss, reduces the fertilization cost in crop planting, slows down soil degradation, and improves the quality and the yield of crops; and more importantly chitosan has good self-degradation function, does not cause any pollution to soil, and conforms to the concept of sustainable development.

The invention relates to the field of composite fertilizers, and concretely relates to a long-acting sustained-release composite fertilizer rich in organic materials. The fertilizer is prepared from the following raw materials in parts by weight: 10-15 parts of 1250-2000 mesh diatomite, 12-15 parts of ammonium humate, 8-10 parts of triple superphosphate, 5-6 parts of pumace, 6-8 parts of bean dregs, 4-5 parts of grass meal, 5-7 parts of lees vinegar, 1-2 parts of white sugar, 0.5-1 part of xylose, 18-20 parts of urea, 5-6 parts of borax, 8-10 parts of sodium carboxymethylcellulose, 6-8 parts of redispersible latex powder, 2-3 parts of ammonium ferric citrate, 8-10 parts of ammonium dihydrogen phosphate, 0.1-0.2 part of calcium stearate and 4-5 parts of an auxiliary agent. The raw materials of the composite fertilizer are rich in multiple organic materials, so that the soil activity is effectively improved, and the adverse influence of long-term fertilization on soil is improved; dual cladding on nutrient is formed by utilizing diatomite and a sustained-release coating agent in the production technology, so that nutrient is not easy to loss, the utilization rate is greatly improved; and release of nutrient is long-acting and efficient, and sufficient nutrient and balanced soil environment help to improve both crop output and quality, and the plantation benefit is increased.

The invention discloses a process for preparing chitosan-based self-assembled nano microcapsule and the pharmaceutical release and regulation method, wherein the nano pharmaceutical microcapsule is prepared through using N,N-dialkylated chitosan as the capsule material, employing modified retrograde evaporation method according to the principle of the self-assembly technique, i.e. carrying out a second supersonic operation before centrifugal separation. The obtained microcapsule has a dimension distribution between 100-250nm.

The invention discloses a freeze-dried nanometer powder injection of ursolic acid and a preparing method thereof. It major composes of active material of ursolic acid, complex vehicle of nanometer powder, excipient of freeze-drying. Compared to other popular preparations, its advantages are high target application of liver, concentrate on the affects, increase curative effect, decrease side effect, high dispersity and stability. It is prepared through dissolving ursolic acid as active raw material in medical organic solvent, adding complex vehicle of bean lecithin and stearic acid, stirring while heating until reaction completed, adding distilled water, adding excipient, stirring while heating until reaction completed, filtering with microporous membrane and freeze-drying the filtrate. Its average particle size is 209.5 mm, drug loading is 25.2%. it is for inhibiting and treating liver cancer, decreasing expression of p53, bcl-2 and topo-II.

The invention discloses a production method of a medical flexible gradual-change vessel catheter and belongs to the technical field of medical equipment production. The production method includes: using nylon block copolymer, hydroxyethyl methylacrylate-methyl methacrylate and collagen as the raw materials; using a LiBr or LiCl aqueous solution to extract the crushed and sterilized collagen; centrifuging; performing dialysis in ultrapure water to obtain dialysate; centrifuging the obtained dialysate to remove precipitates, and concentrating to obtain a mixed collagen aqueous solution; adding acovalent cross-linking agent, sufficiently and evenly mixing, and injecting into a sterile die to obtain a semi-finished flexible gradual-change vessel catheter; placing into a sterile plate, freezing, performing overnight freeze drying in a freeze vacuum drying machine under zero degree, and taking out the catheter obtained after the freeze drying from the die. The flexible gradual-change vesselcatheter produced by the method is good in bioactivity and biocompatibility, capable of achieving in-vivo natural degradation and capable of promoting the regeneration of long-distance injured peripheral nerves.

The invention discloses a slow-release chlorine dioxide disinfection card taking zeolite as a carrier, and mainly relates to the field of chlorine dioxide disinfection. The invention relates to a chlorine dioxide sustained-release agent and a preparation method thereof, and aims to overcome the defects of unstable chlorine dioxide gas, short product preservation time and the like in the prior art. According to the invention, a natural zeolite material is used as a carrier and is compounded with sodium chlorite and a combined catalyst, and moisture and carbon dioxide in air are used for participating in a reaction to generate slow-release chlorine dioxide, so that the release rate of chlorine dioxide gas is artificially controllable, and bacteria and viruses are killed. The disinfection card has an ultra-long slow-release capability of more than 30 days, and plays an effective role in the aspects of protecting susceptible people from virus invasion, purifying harmful components in air and the like.

The invention relates to the field of composite fertilizers, and concretely relates to a long-acting sustained-release composite fertilizer rich in organic materials. The fertilizer is prepared from the following raw materials in parts by weight: 10-15 parts of 1250-2000 mesh diatomite, 12-15 parts of ammonium humate, 8-10 parts of triple superphosphate, 5-6 parts of pumace, 6-8 parts of bean dregs, 4-5 parts of grass meal, 5-7 parts of lees vinegar, 1-2 parts of white sugar, 0.5-1 part of xylose, 18-20 parts of urea, 5-6 parts of borax, 8-10 parts of sodium carboxymethylcellulose, 6-8 parts of redispersible latex powder, 2-3 parts of ammonium ferric citrate, 8-10 parts of ammonium dihydrogen phosphate, 0.1-0.2 part of calcium stearate and 4-5 parts of an auxiliary agent. The raw materials of the composite fertilizer are rich in multiple organic materials, so that the soil activity is effectively improved, and the adverse influence of long-term fertilization on soil is improved; dual cladding on nutrient is formed by utilizing diatomite and a sustained-release coating agent in the production technology, so that nutrient is not easy to loss, the utilization rate is greatly improved; and release of nutrient is long-acting and efficient, and sufficient nutrient and balanced soil environment help to improve both crop output and quality, and the plantation benefit is increased.

The invention particularly discloses a water-retaining slow-release fertilizer based on carboxymethyl chitosan and a preparation method thereof. The method relates to synthesis of a polymer slow-release fertilizer and a preparation process of a water-retaining agent. A polymer fertilizer is successfully introduced into a water-retaining agent network in a physical blending manner. A linear polymerslow-release fertilizer synthesized by taking urea, formaldehyde and monopotassium phosphate as raw materials serves as a nutrient source and is physically wound in a water-retaining agent network, and the nutrients can be diffused into soil along with moisture to provide moisture and nutrients necessary for crop growth. The fertilizer overcomes the defects of complex preparation process, high cost and the like of a double-coating coated fertilizer, has the advantages of simple preparation process and low price, and can be widely applied to desert vegetation.

The invention discloses an efficient broad-spectrum safe environment-friendly disinfectant capable of fumigation. The novel veterinary disinfectant disclosed by the invention is convenient and safe to use, has curative effect, has broad-spectrum anti-pathogen microbial activity, and does not pollute an environment. The disinfectant is mainly characterized in that the disinfectant can be applied to fumigation disinfection and comprises the following ingredients in percentage by weight: 65-75% of sodium dichloroisocyanurate, 4-6% of sodium carboxymethyl cellulose, 3-6% of sodium carbonate, 3-8% of anhydro sugar, and 5-25% of anhydrous sodium sulphate. The disinfectant has extremely strong killing capacity on pathogenic bacteria, spores, fungi, viruses and the like and can be applied to effective prevention and control of the occurrence and spread of infectious diseases of livestock, poultry and the like.

The invention relates to the field of compound fertilizers, and particularly relates to a slow-release compound fertilizer containing natural worm-expelling components. The fertilizer is prepared from the following raw materials in parts by weight: 10-15 parts of kieselguhr of 1250-2000 meshes, 10-12 parts of potassium sorbate, 16-19 parts of ammonium dihydrogen phosphate, 4-5 parts of magnesium chloride, 10-12 parts of sodium pyrophosphate, 22-23 parts of well-rotted farmyard manure, 6-8 parts of dried tempeh fine powder, 4-6 parts of formosan lattuce herb leaf and stem, 5-6 parts of Tephrosia purpurea stem and leaf, 4-5 parts of burdock dreg powder, 1-3 parts of starch aluminum octenylsuccinate, 1-2 parts of potassium persulfate, 10-12 parts of acrylamide, 1-2 parts of negative ion powder, 2-4 parts of medical stone powder, 6-8 parts of polymeric ferric silicate sulfate and 4-5 parts of assistant. According to the invention, the compound fertilizer formula has wide raw material sources and multiple nutrients; slurry of the formosan lattuce herb leaf and stem and the Tephrosia purpurea stem and leaf contains natural worm-expelling components, so that worms and ants can be prevented from nibbling the fertilizer; and by technically using the kieselguhr and the slow-release coating agent containing the negative ion powder, the nutrients are doubly coated, so that the nutrients are less prone to loss, and the fertilizer efficiency can last longer. In practical application, the compound fertilizer can obviously improve the yield and quality of crops and increase economic benefits.

The invention discloses a production method of a medical flexible gradual-change vessel catheter and belongs to the technical field of medical equipment production. The production method includes: using nylon block copolymer, hydroxyethyl methylacrylate-methyl methacrylate and collagen as the raw materials; using a LiBr or LiCl aqueous solution to extract the crushed and sterilized collagen; centrifuging; performing dialysis in ultrapure water to obtain dialysate; centrifuging the obtained dialysate to remove precipitates, and concentrating to obtain a mixed collagen aqueous solution; adding acovalent cross-linking agent, sufficiently and evenly mixing, and injecting into a sterile die to obtain a semi-finished flexible gradual-change vessel catheter; placing into a sterile plate, freezing, performing overnight freeze drying in a freeze vacuum drying machine under zero degree, and taking out the catheter obtained after the freeze drying from the die. The flexible gradual-change vesselcatheter produced by the method is good in bioactivity and biocompatibility, capable of achieving in-vivo natural degradation and capable of promoting the regeneration of long-distance injured peripheral nerves.

The invention discloses a modified Al2O3 / spice composite material capable of regulating and controlling slow release performance and application of the composite material in tobaccos, according to the Al2O3 modified material prepared through the method, tobacco stems with low utilization value in tobacco raw materials serve as a base plate, the base plate is combined with preparation of the Al2O3 modified material, and the application of the tobacco stems is greatly widened. According to the invention, the release rate of the perfume in the adsorption material / perfume composite material is controlled by controlling the temperature for the first time, and furthermore, the invention finds the adsorption material with excellent perfume storage capability and controllable slow release performance. When the prepared modified Al2O3 / spice composite material is applied to cigarettes, the smoking quality of the cigarettes can be effectively improved, and the aroma characteristic, the smoke characteristic and the taste characteristic of the cigarettes are obviously improved.

The invention belongs to the technical field of organic cultivation substrates, in particular to a green moisture-preserving slow-release composite organic cultivation substrate and a preparation method thereof. In the invention, raw materials such as edible fungus fermented chaff, attapulgite clay and potassium humate are chemically polymerized, physically cross-linked and mixed to obtain an organic cultivation substrate with the function of moisture conservation and slow release. The method of the invention is simple in process and low in cost, and the prepared organic cultivation substrate has high water absorption and slow-release nutrient effects, and overcomes the shortcomings of traditional polymer water-absorbing resins such as single function, poor gelation, difficult degradation, and high preparation cost . The invention also solves the problems of long composting and fermentation period of organic / inorganic compound organic cultivation substrate, easy loss of nutrients and the like. It is suitable for water absorption, water retention, fertilizer retention, and fertilizer release in agricultural and forestry soils. After use, it can improve soil structure, improve crop resistance to drought and saline-alkali, enhance soil water absorption and moisture retention, reduce fertilizer loss and environmental pollution, and significantly increase crop production.

The invention relates to the field of compound fertilizers, and particularly relates to a low-cost slow-release compound fertilizer containing an okra seed. The fertilizer is prepared from the following raw materials in parts by weight: 10-15 parts of kieselguhr of 1250-2000 meshes, 12-14 parts of potassium chloride, 8-10 parts of ordinary superphosphate, 25-28 parts of urea, 6-8 parts of ammonium hydrogen carbonate, 12-15 parts of diammonium hydrogen phosphate, 2-4 parts of sodium tetraborate, 12-15 parts of earthworm cast, 18-20 parts of pond silt, 8-10 parts of tea pulp, 2-4 parts of shrimp shell meal, 1-2 parts of sodium naphthaleneacetate, 4-5 parts of Chinese cabbage dreg, 2-3 parts of amino-oligosaccharin, 6-8 parts of okra seed, 10-12 parts of water-dispersible epoxy modified acrylate resin solution, 1-3 parts of dimethyl silicone oil, 1-2 parts of sodium caseinate, 2-3 parts of Pulullan, 2-4 parts of zinc gluconate, 6-8 parts of table vinegar and 4-5 parts of assistant. According to the invention, the compound fertilizer is wide in raw material sources, cheap and accessible; and by technically using the kieselguhr and the coating agent, the nutrients are doubly coated, so that the nutrients (especially minor elements) therein can be effectively protected, and the fertilizer efficiency can last longer. Besides, the compound fertilizer can improve the yield and quality of crops, thereby truly realizing low cost and high profit.

The invention relates to a method for preparing monodisperse mesoporous bioactive glass microspheres through a template method, belonging to the field of biomedical materials. A silicon source, a phosphorus source, a calcium source, an iron source, an alkali metal or alkaline-earth metal source is adopted as a raw material, a triblock copolymer or alkyl quaternary ammonium salt type cation is taken as a surfactant, and an in-situ sol-gel method is performed in a three-dimensional ordered macroporous polymer or a carbon template to synthesize the ordered mesoporous bioactive glass microspheres. The bioactive glass microspheres prepared according to the invention have the characteristics of good biocompatibility, biodegradability, ordered mesoporous structure, higher specific surface area, magnetism, monodispersibility of particles, environmental stability and the like; and in comparison with various medicament delivery carrier materials which are extensively researched currently, the bioactive glass microspheres have more comprehensive advantages and further have broad application prospects as novel medicament controlled release carrier materials.

The invention discloses a compound potassium ferrate slow release disinfectant as well as a preparation method and a usage method thereof, and belongs to the field of the advanced treatment of tail water. The compound potassium ferrate slow release disinfectant is prepared from the following preparative raw materials of 20 parts of sodium hydroxide, 10 to 15 parts of potassium hydrate, 10 to 15 parts of calcium hypochlorite, 15 to 18 parts of iron nitrate, 100 to 120 parts of calcium-based bentonite, 100 to 200 parts of beta-cyclodextrin and 10 to 20 parts of epoxy chloropropane. When being used, the compound potassium ferrate slow release disinfectant is used by being combined with 200 to 400 parts of powdery activated carbon and 20 to 40 parts of carboxymethyl cellulose to be made into an activated carbon column with the granularity of 5mm. A water treating agent prepared by the preparation method has good stability and high oxidizability, has persistent oxidizing ability, is persistent in disinfection, is good in effect, does not generate a secondary pollutant, is convenient and quick to use, also hast he ability of removing a little COD (Chemical Oxygen Demand), and can be used for effectively decreasing the chromatic value of the tail water; most raw materials are low-cost and are easily obtained.

The invention discloses an acid-resistant glycolipid modified liposome and an application thereof. The glycolipid modified liposome is prepared from soybean lecithin, cholesterol and glycolipid according to the mass ratio of (1-5): 1: (1-5), has acid resistance, can tolerate the pH of 3.0-7.0, is good in dispersity and has the particle size of 70-90 nm. The lipid-modified liposome can directly remove a helicobacter pylori biological membrane. The invention also verifies that by using the glycolipid modified lipidosome to wrap antibiotics, effective and continuous slow release of drugs in a gastric acid environment can be realized, and the glycolipid modified lipidosome has the functions of gastric retention, mucous barrier penetration and helicobacter pylori biological membrane, so that the bioavailability of amoxicillin is remarkably improved. Helicobacter pylori infection can be eradicated, and treatment of helicobacter pylori related gastritis and gastric ulcer is promoted.

The invention discloses a preparation method of a modified konjac glucomannan loaded copper slow release agent and application in algal bloom control. Konjac flour is adopted as a raw material to prepare loaded copper modified konjac glucomannan; with blue algae, green algae, diatom, pyrrophyta and the like as indoor experimental algae, the result indicates that the modified konjac glucomannan loaded copper realizes an obvious inhibiting effect on the growth of different algae and has a characteristic of slow release controlling on algae growth. The loaded copper slow release agent has an obvious control effect on algal bloom of the blue algae, the green algae, the diatom and the pyrrophyta in a natural water body; field experiments prove that the loaded copper slow release agent can prevent outbreak of algal bloom within 1-3 years. By adding 0.5-1.0g / L of the loaded copper modified konjac glucomannan into the water body, the Cu<2+> is lower than the standard limit in the Standards forDrinking Water Quality and the Cu<2+> content of class-III water quality in the Environmental Quality Standards for Surface Water. The slow release algae control agent has the advantages of high efficiency and quickness of copper sulfate; the slow release ability also avoids the shortcoming of extremely high local concentration of copper sulfate caused by direct adding of copper sulfate, and is also natural and nontoxic and biodegradable, and thus is a natural, safe and efficient algae control agent with a broad application prospect.

The invention relates to the technical field of traditional Chinese medicinal health products, and concretely relates to a dendrobium capsule. The dendrobium capsule is prepared through the followingsteps: putting giant salamander skins in a beater, beating the giant salamander skins to form a slurry, adding rice vinegar with the volume 10 times that of the slurry into the slurry, uniformly mixing the slurry and the rice vinegar, adding pepsin accounting for 1% of the weight of the slurry, carrying out enzymatic hydrolysis, centrifuging the obtained enzymatic hydrolysate, taking the obtainedsupernatant, and concentrating the supernatant to obtain a concentrate; adding sodium caseinate into the concentrate, and treating the concentrate at a temperature of 75 DEG C at a rotating speed of 8000 r / min for 30-35 min to obtain an emulsion; adding chitosan, xylooligosaccharides and flaxseed gum into the emulsion, homogenizing the emulsion and the added substances one time at a temperature of50-52 DEG C under a pressure of 22-25 Mpa to obtain a homogeneous material, placing the homogeneous material in a pill dropping machine for producing pills, and drying capsules dropped from the discharging opening of the pill dropping machine in 90-98 DEG C hot air for 10-12 min to obtain capsule shells; and filling the dendrobium capsule shells with dendrobium powder, and carrying out sealing and packaging to obtain the dendrobium capsule.

The invention relates to the field of compound fertilizers, particularly a cony-hair-modified polyurethane coated high-efficiency slow-release compound fertilizer. The fertilizer is prepared from the following raw materials in parts by weight: 10-15 parts of 1250-2000-mesh kieselguhr, 11-12 parts of dry wormcast, 8-10 parts of clover stover, 10-12 parts of Lemna minor, 3-4 parts of coriander seed, 4-6 parts of sodium pyrophosphate, 2-4 parts of light calcium carbonate, 2-4 parts of ferrous sulfate, 6-8 parts of yellow seriflux, 8-10 parts of wood dust ash, 10-12 parts of calcium hydrogen phosphate dihydrate, 6-8 parts of dehydrated vegetable powder, 2-4 parts of white granulated sugar, 0.1-0.3 part of ammonium persulfate, 3-4 parts of zinc sulfate, 5-6 parts of cluster redpepper leaf, 1-3 parts of silane coupling agent KH550, 0.1-0.2 part of cony hair, 20-23 parts of water-based polyurethane emulsion and 4-5 parts of assistant. The compound fertilizer has the advantages of wide raw material sources and rich and multiple nutrients, and can enhance the activity of soil; in the aspect of the production technique, the kieselguhr and cony-hair-modified polyurethane coating agent are utilized to form dual coatings on the nutrients, and thus, have favorable enduring coating slow-release control capability, so that the nutrient release is enduring and efficient, and the utilization ratio of the fertilizer is high; and the compound fertilizer can obviously enhance the crop yield and improve the product quality.

The present invention provides a sericin-alginate composite hydrogel and a preparation method thereof, the method comprising: 1) weighing the cocoons of silkworm silk fibroin-deficient mutant varieties, extracting with LiBr or LiCl aqueous solution, and then dialysis and purification, Concentrate to obtain a non-degradable sericin aqueous solution with a mass percentage concentration of 1.5-10%; 2) prepare an alginate aqueous solution with a mass percentage concentration of 0.1-10%; 3) make the above-mentioned The sericin aqueous solution and the alginate aqueous solution are mixed at a ratio of 100-0.01:1 to form a sericin-alginate composite hydrogel, and the cross-linking agent includes an ionic cross-linking agent and / or a covalent cross-linking agent. The scheme of the present invention can obtain sericin-alginate composite hydrogel with interpenetrating network, and the obtained composite hydrogel not only has excellent fluorescence characteristics, deformation memory and elastic modulus controllability, but also has good Biocompatibility, cell adhesion, can support cell survival, proliferation and migration for a long time.

The invention provides a chitosan-sericin composite biological scaffold, a preparation method and an application. The invention adopts acetic acid solution as a solvent to dissolve chitosan to obtain a chitosan solution; adopts silkworm cocoons of a silk fibroin-deficient mutant variety silkworm to prepare a sericin aqueous solution; mixes the chitosan solution and the sericin aqueous solution and injects it into a mold adding a cross-linking agent to form a chitosan-sericin composite hydrogel; freeze-drying the chitosan-sericin hydrogel to obtain a chitosan-sericin composite biological scaffold. The invention also provides a composite biological scaffold carrying nerve growth factor NGF for the treatment of peripheral nerve entrapment. The present invention has good biocompatibility, high porosity and degradability, and the degradation product also has neurotrophic effect, and at the same time, the composite scaffold has the functions of antibacterial and anti-adhesion. It can effectively promote the repair of peripheral nerve entrapment injury.