The invention discloses a method for producing pleurotus cornucopiae through bagasse, mulberry stems and corn residues. According to the method, thermophilic fermentation of pleurotus cornucopiae cultivation materials is carried out in advance, namely, the bagasse, the mulberry stems and the corn residues are smashed, lime and thermophilic bacteria are added into the smashed mixture, water is sprayed after intensive mixing, the mixture is coated with a film to ferment, then the cultivation materials are turned, wheat bran and fish meal are scattered into the cultivation materials, mixed thoroughly, piled and coated with a film to ferment for two days, turning and piling are carried 2-3 times in the mode, the cultivation materials are mixed thoroughly and heated to 70-80 DEG C, sterilization of 15 hours is carried, then the cultivation materials are cooled to the indoor temperature, strain inoculation is carried out, and the pleurotus cornucopiae can grow after 8-10 days. According to the method, thermophilic bacteria fermenting raw materials are utilized and can become thoroughly decomposed easily, the biological efficiency of the raw materials is improved, the yield of the pleurotus cornucopiae is increased, the temperature of the high temperature phase is increased, the growth temperature of the pleurotus cornucopiae can be achieved fast, and the energy consumption of a mushroom house is reduced.