116results about "Sulfuric acid esters preparation" patented technology

The invention discloses a phloretin derivative and application thereof in preparation of a medicine for treating diabetes, relates to the technical field of medicines, and in particular relates to a compound as shown in a formula (1) and alpha-glucosidase inhibitory activity of the compound. Pharmacological experiment results show that the compound shown in the formula (1) has extremely high alpha-glucosidase inhibitory activity, so that the generation of glucose is inhibited, and the pharmacological action of resisting diabetes mellitus is exerted through the action mechanism.

The invention discloses a phloretin derivative and application thereof in a medicine for treating non-alcoholic fatty liver related to diabetes mellitus, relates to the technical field of medicines, and in particular relates to a compound shown in a formula (1) and activity of the compound for relieving the non-alcoholic fatty liver related to the diabetes mellitus metabolic syndrome. Pharmacological experiment results show that the compound shown in the formula (1) can significantly relieve hepatomegaly, reduce lipid droplets in liver tissues, recover the morphology of liver cells, reduce the content of total cholesterol, triglyceride and low-density lipoprotein in blood, reduce related inflammatory indexes and enhance antioxidant activity.

The invention discloses a method for synthesizing a dichloroacetyl compound, which comprises the following steps: tetrachloroethylene and an acid are subjected to an addition reaction at 100-200 DEG C to obtain an adduct, then the adduct is subjected to an acidolysis, hydrolysis or alcoholysis reaction to obtain the dichloroacetyl compound, the acid for the addition reaction is at least one of sulfuric acid, trifluoromethanesulfonic acid, methanesulfonic acid and phosphoric acid, and the acid for the alcoholysis reaction is at least one of sulfuric acid, trifluoromethanesulfonic acid, methanesulfonic acid and phosphoric acid. The molar ratio of the tetrachloroethylene to the acid is 1: (1-10). By controlling the types of acids and increasing the temperature of the addition reaction, the addition reaction of tetrachloroethylene and acids in the absence of a catalyst is realized. Double bonds of tetrachloroethylene and hydrogen protons are subjected to an addition reaction in a strong acid environment to form a cationic intermediate, then the cationic intermediate is combined with acid radical anions to form an adduct, and the adduct intermediate is high in activity, unstable and free of separation and can be directly subjected to a hydrolysis reaction, an acidolysis reaction or an alcoholysis reaction with another substrate (such as water, acid or alcohol) respectively. The synthesis of dichloroacetyl series compounds is realized, and the route has universality and diversity.

The invention provides a polycarbonate polyether sulfate salt surfactant as well as a preparation method and application thereof, and belongs to the technical field of surfactants. The polycarbonate chain segment endows the polymer with certain rigidity and stability, the polyether chain segment provides good hydrophilicity and flexibility, and the sulfate salt group enhances the surface activity of the polymer. The polycarbonate polyether sulfate salt surfactant provided by the invention is strong in emulsibility, good in low-temperature solubility and strong in capability of reducing surface tension at low concentration, a rigid structure of a polycarbonate chain segment can be more easily decomposed by microorganisms, environmental residues are reduced, and the surfactant is environment-friendly. The method can be used in the fields of personal care products, household cleaning products, textile printing and dyeing assistants, coating and ink assistants or oil displacement agents for oil fields.

The invention discloses an organic long-chain zinc salt for a zinc secondary battery electrolyte and a preparation method and application thereof. The organic long-chain zinc salt comprises a long-chain group, an acidic group and zinc ions, the long-chain group comprises at least one of substituted or unsubstituted C8-16 alkyl groups, and the acidic group comprises at least one of a sulfonic acid group, a phosphoric acid group and a sulfuric acid group. The organic long-chain zinc salt serving as an electrolyte salt of the zinc secondary battery can be adsorbed on the surface of zinc to form a protective layer, so that the cycle life and the capacity retention ratio of the zinc secondary battery are effectively improved.

The present invention discloses a cold-water instant film softener and a preparation method thereof. The cold-water instant film softener has the general structural formula: #imgabs0# and is prepared from N,N'-bis(2-hydroxyethyl)ethylenediamine, 12-hydroxystearic acid, methoxypolyethylene glycol glycidyl ether, and diethyl sulfate as raw materials. The film softener prepared using the preparation method provided by the present invention can be rapidly dispersed and dissolved in a normal temperature water environment, dissolving thoroughly without any residue, greatly improving the fabric processing rate and reducing energy consumption and processing costs. The treated fabric is soft and fluffy, has little effect on the fabric color, and does not suffer from yellowing, greatly improving the fabric's texture and added value. The preparation process is simple, highly controllable, and requires low production equipment. The production process does not emit pollutants, is safe and environmentally friendly, uses inexpensive and readily available raw materials, and is low in cost. The softener is suitable for industrial production.

The invention relates to a preparation method of a p-cresol sulfate (PCS) detection kit by using a chemiluminescence immunoassay technology, and particularly relates to a preparation method of a p-cresol sulfate (PCS) detection kit. P-cresol sulfate is a protein-bound uremic toxin in a human body, has small molecular weight and poor immunogenicity, and when a corresponding antibody is prepared, a hapten and a specific macromolecular carrier need to be coupled to prepare a complete antigen. According to the invention, the antibody with good specificity and strong affinity is successfully prepared by designing and transforming the hapten. The invention mainly relates to design and synthesis of a sulfuric acid p-cresol hapten, preparation of a sulfuric acid p-cresol complete antigen and an anti-sulfuric acid p-cresol antibody, a method for measuring the concentration of sulfuric acid p-cresol, and composition and components of a reagent. The design and synthesis of the hapten mainly comprise design and chemical synthesis of a sulfuric acid p-cresol derivative. The p-cresol sulfate derivative disclosed by the invention has a structure as shown in a formula (I): # imgabs0 #, wherein R is-(CH2) n-COOH, and n is 4.

This invention provides a polymer solid electrolyte monomer and its preparation method, as well as a secondary battery. The polymer solid electrolyte monomer provided by this invention has the structure shown in Formulas 1-4. The secondary battery provided by this invention introduces the polymer solid electrolyte monomer and a certain functional material solution, both of which are used on the positive electrode side. Simultaneously, an acrylate monomer is introduced on the negative electrode side. After battery assembly, heat treatment is performed to initiate gradient in-situ polymerization of the precursors on both the positive and negative electrode sides. Specifically, cationic polymerization initiates mild polymerization on the positive electrode side, free radical polymerization initiates high polymerization on the negative electrode side, and the two monomers interpenetrate at the separator to complete cross-linking copolymerization, thereby forming a gradient polymerization system with increasing polymerization degree from the positive to the negative electrode. The in-situ solid battery prepared using this method has lower internal resistance and faster Li + This improves the electrochemical performance of the battery by creating a transmission channel.

The application relates to the technical field of surfactants, in particular to a pentadecyl phenol alkoxyl ether sodium sulfate surfactant and a preparation method thereof. The preparation method of the pentadecyl phenol alkoxyl ether sodium sulfate surfactant comprises the following steps: after pretreatment, cashew nut shell liquid is selectively hydrogenated to obtain pentadecyl phenol with a specific composition; then, alkoxylization reaction is carried out under the condition of an alkaline catalyst to obtain pentadecyl phenol polyalkoxyl ether; and the pentadecyl phenol polyalkoxyl ether is sulfated and neutralized to obtain the pentadecyl phenol alkoxyl ether sodium sulfate surfactant. The surfactant improves the problem that the activity of the surfactant is reduced when the saturation of the pentadecyl phenol is too high or too low; ensures that the final product has good fluidity at low temperature, guarantees the continuity of production, effectively reduces the occurrence of over-sulfation; and simultaneously improves the production efficiency and reduces the cost.

The need for a liquid hand dishwashing composition which is more environmentally sustainable while also providing a desired viscosity and being readily diluted in cold water, is met by formulating the liquid hand dishwashing detergent composition using alkyl glycol sulfate anionic surfactant and optionally further anionic surfactant in a weight ratio of from 1:1 to 1:0.

The present invention discloses a process for removing dioxane from fatty alcohol ether sulfate, comprising: a process for removing dioxane from a fatty alcohol polyoxyethylene ether sulfate material in a vacuum tube-type remover, wherein the material is partially output as a discharge product and partially output as a recycled material through a delivery pump; the recycled material passes through a venturi ejector and enters a neutralizer simultaneously with fatty alcohol polyoxyethylene ether sulfate, alkali, and water for a neutralization reaction; at the same time, a certain flow of mixed gas is delivered through the suction end of the venturi ejector; the outlet material of the neutralizer enters the vacuum tube-type remover through a pipeline, and dioxane in the material is removed under vacuum. The present invention further innovates the original continuous tube vacuum neutralization system by introducing a combination of steam and non-condensable gas before the neutralizer, thereby effectively improving the dioxane removal efficiency of the system; the dioxane residue of the product removed by the system can be reduced from the original 10 mg / kg to 5 mg / kg.

The purpose of the present invention is to provide a fluorine-containing anionic surfactant having excellent surface tension reduction ability and water solubility due to the use of a fluorine-containing compound composed of a perfluoroalkyl group having at most 6 carbon atoms, which is considered to have low bioaccumulation.　A fluorine-containing compound represented by general formula (1), a method for producing the same, an intermediate for producing the compound, and a surfactant using the compound, method, and intermediate are used. (In formula (1), Rf1, Rf2, and Rf3 are each independently a C1-C6 perfluoroalkyl group, X1, X2, and X3 are each independently a C1-C8 linear alkylene group which may contain an ethereal oxygen atom, and Y is a substituent containing an anionic polar group.)

To provide a liquid hand dishwashing detergent composition which, while providing good foaming properties, viscosity, and stability, still has high biodegradability and a high concentration of renewable components.SOLUTION: The need for a liquid hand dishwashing composition which, while including a surfactant derived from a more renewable supply source, still provides good performance, in particular foam longevity in the presence of oily and fatty particulate soils and hard water, as well as oily and fatty soil removal, is met by formulating the liquid hand dishwashing composition with an alkylalkanolamide sulfate anionic surfactant in combination with an alkyl sulfate anionic surfactant.SELECTED DRAWING: None

Methods for producing methyl methacrylate (MMA) are described. The methods include mixing or combining a treatment product that includes at least one amide of a fatty acid or fatty acid ester to a solution that includes MMA or precursors thereof or a part of the product produced, and that further has polymer asphaltenes present. Methods and products used to disperse polymer asphaltenes in a solution of spent acid and water are further disclosed that utilize at least one amide of a fatty acid or fatty acid ester.

The need for a liquid hand dishwashing composition which is more environmentally sustainable while also providing a desired viscosity and being readily diluted in cold water, is met by formulating the liquid hand dishwashing detergent composition using alkyl glycol sulfate anionic surfactant and optionally further anionic surfactant in a weight ratio of from 1:1 to 1:0.

This invention discloses a viscosity reducer and a slurry preparation method suitable for preparing coal-water slurry from high-viscosity organic wastewater. The high-viscosity organic wastewater viscosity reducer is prepared by adding naphthoic acid (obtained from methylnaphthalene oxidation) to ethylene oxide and propylene oxide in a certain proportion. The slurry preparation method involves adding sodium naphthalenesulfonate as an additive to the high-viscosity organic wastewater after viscosity reduction to obtain the coal-water slurry. This invention overcomes the disadvantage that high-viscosity organic wastewater is unsuitable for preparing coal-water slurry, successfully using a viscosity reducer to reduce the viscosity of high-viscosity organic wastewater and obtain a high-coal-content coal-water slurry.

The present invention provides a phloretin derivative and its use in preparing a medicament for treating diabetes, relating to the field of medical technology, and particularly to a compound represented by formula (1) and its α-glucosidase inhibitory activity. Pharmacological experimental results show that the compound represented by formula (1) has extremely high α-glucosidase inhibitory activity, thereby inhibiting the production of glucose, and further exerting an anti-diabetic pharmacological effect through this mechanism of action.

The present invention relates generally to methods for producing renewable detergent compounds. More specifically, the invention relates to methods for producing detergent intermediates, including bio-linear alkylbenzene (LAB), bio-alcohols, and long chain bio-paraffins, from natural oils.

The invention relates to the technical field of organic synthesis, in particular to soybean-based morpholine quaternary ammonium salt and a preparation method thereof, the structural formula of the soybean-based morpholine quaternary ammonium salt is shown as (I), the preparation method comprises the following steps: S1, assembling soybean fatty acid and morpholine or morpholine derivatives through amidation reaction or esterification reaction, and after the reaction is finished, purifying to obtain soybean-based morpholine quaternary ammonium salt; a soybean-based quaternary ammonium salt synthesis precursor is obtained; and S2, placing the soy-based morpholine quaternary ammonium salt synthesis precursor and an alkylating reagent in a solvent for reaction, and after the reaction is finished, purifying to obtain the soy-based morpholine quaternary ammonium salt. The soy-based morpholine quaternary ammonium salt is prepared through a two-step one-pot method, the method is simple in synthesis process and environmentally friendly, and no catalyst or strong acid or strong base needs to be added in the reaction process.

This invention discloses a method for preparing organic sulfates, comprising the following steps: using persulfate as the sulfate source, and achieving the functional group transformation of a free radical precursor compound through the free radical anion of the sulfate ion, thereby preparing the organic sulfate. This invention uses persulfate as the source and, through a free radical addition mechanism, acts on the free radical precursor substrate. Persulfate, as a sulfate free radical anion, participates in the functional group transformation of the organic compound, resulting in the efficient synthesis of organic sulfates.

This invention belongs to the field of surfactant preparation technology, specifically relating to a method for preparing a sulfate ester salt type surfactant. The method includes the following steps: olefins and concentrated sulfuric acid are separately introduced into a microchannel reactor equipped with a catalyst section and mixed and reacted under ultrasonic conditions to obtain an intermediate product; an aqueous solution of NaOH or KOH is added to the intermediate product, the temperature is raised to 90-105℃, and the mixture is stirred and refluxed for 1-2 hours to obtain the sulfate ester salt type surfactant. This invention combines a microchannel reactor with fine chemical synthesis and successfully synthesizes secondary alkyl sulfates. By accelerating the reaction with a catalyst and ultrasound, increasing the phase contact area, and controlling the reaction temperature at a low level, the degree of olefin sulfation is greatly improved, thereby increasing the yield of secondary alkyl sulfates. The method is safe, environmentally friendly, easy to operate, simple in process, and easy to control. It is expected that production can be scaled up to industrial scale through array arrangement.

The invention provides a surfactant for an oil-displacing agent, the oil-displacing agent and a preparation method of the oil-displacing agent. The method comprises the following steps: mixing a C10-C18 alkyl alcohol material separated from crude oil of a target oil reservoir or a high-salinity and high-temperature oil reservoir of a target oil-displacing agent surfactant with concentrated sulfuric acid to obtain a mixture for preparing the surfactant, reacting at 55-75 DEG C, cooling a reaction product, adding hydroxide to adjust the pH value to 6.8-7.2, adding salt to perform salting-out purification, and separating the crude oil from the crude oil in the target oil reservoir or the high-salinity and high-temperature oil reservoir to obtain the target oil-displacing agent surfactant. And preparing to obtain the surfactant for the target oil-displacing agent. The preparation method comprises the following steps: mixing a surfactant for a target oil-displacing agent with an auxiliary surfactant, a polymer additive, a stabilizer, a wetting reversal agent and water to obtain a mixed stock solution; sequentially carrying out ultrasonic treatment and high-pressure homogenization treatment on the mixed stock solution to obtain the target oil-displacing agent. Wherein the wetting reversal agent is a mixture of alkyl trimethyl ammonium bromide, a fluorine surfactant and fatty acid in a mass ratio of (3-4): (0.8-1.5): 1.

The present invention relates to a fatty acid ester quaternary ammonium salt surfactant obtained by performing an amine esterification reaction and a quaternization reaction of fatty acids, which are obtained through one or more steps selected from the group consisting of decolorization, degumming, partial hydrogenation, fatty acid decomposition, and fatty acid purification of coffee oil extracted from coffee grounds, wherein a structure in which fatty acid residues derived from the coffee grounds are esterified accounts for 45 wt% or greater of 100 wt % of the total cationic surfactant. In addition, the fatty acid ester quaternary ammonium salt comprises 40 wt% or greater of diesterquat and 20 wt% or less of triesterquat, and thus has the advantages of high flexibility, good absorption, and excellent long-term storage stability.

The present invention provides a liquid composition for hand-washing dishes that provides good initial foaming while offering foam that can be easily washed away. [Solution] A liquid composition for hand washing dishes is formulated using a combination of an anionic surfactant containing an alkyl glycol sulfate anionic surfactant and an amphoteric / zwitterionic surfactant in a weight ratio of 1:1 to 5:1.

The application relates to the technical field of organic synthesis, in particular to a preparation method of ethyl difluoroacetate, which comprises the following steps: S1, 2,2-difluoro-1,1-dichloroethyl ethyl ether is added into a reaction kettle, concentrated sulfuric acid is added dropwise under stirring at a certain reaction temperature, after the dropwise addition is completed, the reaction is continuously kept for reaction completion, and a compound shown in formula I is obtained; S2, water is added into a reaction container, the compound shown in formula I prepared in the step S1 is added dropwise into the reaction container for hydrolysis reaction at a certain temperature, after the reaction is completed, the reaction is allowed to stand and is separated into layers, and the lower organic layer is ethyl difluoroacetate; the application has the advantages of simple process, easily obtained raw materials, mild reaction conditions, easy control, high product yield, few by-products, reaction condition detection at any time, one-time reaction completion, secondary recovery treatment avoidance, raw material loss reduction and easy industrialized production.

This invention belongs to the field of oilfield chemical enhanced oil recovery (DEOR), and relates to a multi-block polyether-type E-surfactant for DEOR, its preparation method, and its application. The preparation steps are as follows: fatty alcohol, KOH catalyst, and 18-crown ether-6 are sequentially added to a batch reactor, and a triblock AP is obtained through propoxylation or through a combination of propoxylation and ethoxylation. m E n P p or quadblock AP m E n P p E e Any one of the polyether blocks in the formulation is used; under urea catalysis, the obtained polyether block is reacted with aminosulfonic acid to prepare a fatty alcohol polyether ammonium sulfate intermediate; neutralized with NaOH aqueous solution to obtain crude fatty alcohol polyether sodium sulfate, which is then filtered and purified by rotary evaporation to obtain a multi-block polyether type E-surfactant for oil displacement. This surfactant has advantages such as high surface activity, ultra-low interfacial tension, excellent emulsification, low adsorption loss, and good electrolyte resistance, showing good application prospects in tertiary oil recovery.

The application belongs to the technical field of sewage treatment, and particularly relates to a sterilization cleaning agent for treating oilfield produced water by a double membrane method and a synthesis method thereof. The synthesis method comprises the following steps: under the action of a catalyst, epoxypropane is embedded into polyoxypropylene ether in 2,6-bis{[bis(2-pyridylmethyl)amino]methyl}-4-methylphenol in a DMF solvent to obtain an intermediate under high-temperature and sealed space conditions; and then dimethyl sulfate is used for quaternary ammonium reaction on a pyridine group of the intermediate and alkyl end-capping reaction on a polyether group to obtain a product sterilization cleaning agent. The sterilization cleaning agent has the effects of sterilization and chemical cleaning in one, and has the characteristics of good cleaning effect and strong sterilization capacity.

A process includes the steps of contacting an olefin, an alcohol and a metallosilicate catalyst to form oligomers of an alcohol ethoxylate having structure (I), wherein R1 is an alkyl, R2 is an alkyl, and n has a value of 1 to 3; and sulfating the oligomers of Structure (I) to form oligomers of Structure (II), wherein R1 is an alkyl, R2 is selected from the group consisting of an alkyl group, M is selected from the group consisting of a proton, an ammonium cation, a metal cation, a nitrogen cation, a boron cation, a phosphorus cation, triethylamine, triethanolamine, monoethanolamine and combinations thereof, and n has a value of 1 to 3, and wherein 95 mol % or greater of the oligomers of Structure (II) have an n of 1 and 5 mol % or less of the oligomers of Structure (II) have an n of 2 or greater.

The invention relates to the technical field of surfactants, in particular to a pentadecyl phenol alkoxy ether sodium sulfate surfactant and a preparation method thereof. The invention relates to a preparation method of a pentadecyl phenol alkoxy ether sodium sulfate surfactant. The preparation method comprises the following steps: pretreating cashew nut shell liquid, and selectively hydrogenating to obtain pentadecyl phenol with specific composition; carrying out an alkoxylation reaction in the presence of a basic catalyst to obtain pentadecyl phenol polyalkoxy ether; and sulfating the pentadecyl phenol polyalkoxy ether, and neutralizing to obtain the pentadecyl phenol alkoxy ether sodium sulfate surfactant. According to the surfactant, the problem that the activity of the surfactant is reduced due to too high or too low saturation of pentadecyl phenol is solved; it is ensured that the final product has good fluidity at low temperature, production continuity is guaranteed, and oversulfation is effectively reduced; meanwhile, the production efficiency is improved, and the cost is reduced.