Disclosed is a preparing method for casting an inlaid ceramic/metal wear-resisting compound liner. A chemical vapor deposition method is adopted to prepare uniform, continuous and high-purity metal activation coatings on ceramic monomers in various shapes, the kind and the structure of the coatings are changed, wettability between ceramic and metal in the compound process is improved, and the compound quality is improved; finally, through the lost foam casting technology, that is, ceramic reinforcements with the metal activation coatings deposited are fixed into a polystyrene foam model, and casting molding of molten metal is carried out; solid ceramic serves the reinforcements, the ceramic reinforcements are subject to reasonable structural design, and volume fractions and distribution of the reinforcements are controlled; and through forming of the activation coatings on the surfaces of the ceramic reinforcements, the interface combination condition between the ceramic and the metal is improved, operation is simple, easy to implement and low in cost, and the inlaid ceramic/metal wear-resisting compound liner which is good in comprehensive performance and capable of meeting various complex working conditions can be prepared.