The invention discloses a preparation method and use of an anti-aging product. The preparation method of the product is as follows: (1) preparing a
ganoderma lucidum extract: taking a dried
ganoderma lucidum fruiting body, crushing, leaching, adding water at 100±5°C according to a material-liquid
mass ratio of 1:8-10, and repeatedly extracting at least three times, combining the extract, concentrating, and
drying to obtain an extract; (2) preparing a versicolor extract: taking a dried versicolor fruiting body, crushing, leaching, adding water at 100±5°C and repeatedly extracting at least three times, combining the extract, concentrating, and
drying to obtain an extract; (3) mixing 35-42 parts of β-
nicotinamide mononucleotide, 13-16 parts of
ganoderma lucidum extract, 18-21 parts of
cordyceps sinensis or its extract, 6-10 parts of coenzyme Q10, 15-22 parts of versicolor extract, and 1.5-2.5 parts of
yeast by weight. The preparation method provided by the invention is simple and easy to operate, easy to implement industrially, and the obtained product significantly reduces the
cell aging rate, maintains
telomerase activity, and has a good anti-
aging effect.