72 results about "Acibenzolar-S-methyl" patented technology

An electron donating organic material includes a benzothiadiazole compound including (a) a benzothiadiazole skeleton and (b) an oligothiophene skeleton, and having a band gap (Eg) of 1.8 eV or less, and a level of highest occupied molecular orbital (HOMO) of −4.8 eV or less, wherein said benzothiadiazole compound is formed by covalently combining the benzothiadiazole skeleton and the oligothiophene skeleton alternately, a proportion between the benzothiadiazole skeleton and the oligothiophene skeleton is within a range of 1:1 to 1:2 (however, excluding 1:1), and the number of thiophene rings contained in an oligothiophene skeleton is 3 or more and 12 or less.

The invention discloses a soluble electroluminescent green light organic molecule glass material, a preparation method and applications thereof. The material comprises two types of a symmetric substituent benzothiadiazole derivative and a dissymmetric substituent benzothiadiazole derivative. The preparation method of the material comprises: carbazol and fluorine or anthracene are taken as raw materials, a bromide that contains Ar1 is obtained through palladium-catalyzed coupling reaction or cuprous salt catalyzed coupling reaction, and corresponding boric acid ester is generated through a next reaction; the boric acid ester is reacted with 4, 7-dibromo benzothiadiazole or a bromide of benzothiadiazole substituted by soluble resin Ar2 and a tiny molecule luminescent material which is symmetric or dissymmetric is obtained. The luminescent material prepared has good solubility in a solvent with high boiling point and weak polarity and can be purified by the solution method; simultaneously, the luminescent material has good thermal stability and morphologic stability, particularly the luminescent material with the dissymmetric structure has advantages in both synthesis and purification, thus having important application prospect in electroluminescence display, illumination and laser.

The invention relates to conjugated polymers comprising bis(thienocyclopenta)benzothiadiazole units or derivatives thereof, to methods of their preparation, to novel monomer units used therein, to the use of the polymers in organic electronic (OE) devices, and to OE devices comprising the polymers.

The present invention relates to a benzothiadiazole compound represented by the following formula I, and a preparation method and use thereof, the benzothiadiazole compound has the biological activityof inhibiting protein-tyrosine-phosphatase SHP2, can be used as a tool compound to study the biological functional relevance of the protein-tyrosine-phosphatase SHP2 in a cell signal transduction process, and provides a new means for prevention and treatment of cancer and metabolic and immune diseases.

The invention provides a plant protective method and application of inducing immune system of plant by 4-methyl-1,2,3-thiadiazolyl-5-formic acid (NK-F001), sodium 4-methyl-1,2,3-thiadiazolyl-5-formate (NK-F002), 4-methyl-1,2,3-thiadiazolyl-5-ethyl formate (NK-F003) and methenaimde (SZG-7) to generate resistance against the plant virus. The invention also provides an application for improving the plant immunity by combination of two or three of 4-methyl-1,2,3-thiadiazolyl-5-formic acid (NK-F001), sodium 4-methyl-1,2,3-thiadiazolyl-5-formate (NK-F002), 4-methyl-1,2,3-thiadiazolyl-5-ethyl formate (NK-F003), methenaimde (SZG-7), benzthiadiazole (activated ester, BTH), tiadinil (TDL), DL-Beta-aminobutyric acid, virazole, ningnanmycin, antofine, Bingduxing No.1, Bingduxing No.2, XY-13 and XY-30 so as to induce the plant to generate antiviral activity, processing dosage forms of single and mixture preparations, and compositions and contents of effective components in the dosage forms. The invention discloses a plant inducing range and plant antiviral inducing range of compounds and compositions thereof, and application of plant protection in the fields of agriculture and horticulture thereof.

The synthesis, characterization, optical and electrochemical properties of a regioregular copolymer, poly(3-octylthiophene-2,5-diyl-co-3-decyloxythiophene-2,5-diyl) (POT-co-DOT), and an alternating regioregular copolymer poly{(9,9-dioctylfluorene)-2,7-diyl-alt-[4,7-bis(3-decyloxythien-2-yl)-2,1,3-benzothiadiazole]-5′,5″-diyl} (PF-co-DTB) is disclosed. The incorporation of 3-alkoxythiophene units onto the conjugated backbones enhances the electron-donating property of the polymer and lowers its bandgap. The fabrication and performance of photovoltaic cells with bulk heterojunction architecture based on blends of these copolymers with PCBM are also described.

The invention discloses a synthesis method of a 1,2,3-diazosulfide compound. A o-aminothiophenol compound with a structure shown as a formula (I) and tert-butyl nitrite are taken as raw materials, and are subjected to intramolecular diazo-reaction to obtain the 1,2,3-diazosulfide compound with a structure shown as a formula (II); a reaction equation is as follows (shown in the description), wherein R=hydrogen, fluorine, chlorine, ester group, nitro or methyl. The synthesis method has the beneficial effects that (1) the operation is simple and convenient in a preparation process, an obtained product is easy for after-treatment, and large-scale industrialized production is suitable; (2) reaction conditions are mild; (3) the synthesis cost is lowered; (4) a reaction substrate is high in functional group tolerance, is wide in range and easy to prepare; (5) the reaction is efficient, the yield is high, and the reaction efficiency is higher after reaction amplification; (6) environment pollution is avoided, and environment friendliness is achieved.

A conjugated fluorene polymer is provided, which is defined by structure formula (1), wherein: R₁, R₂, R₃, R₄ represent H or C₁-C₂₀ alkyl, x+y=1, x≠0, y≠0, n is a natural number between 1-1000, Ar₁ is a group containing thiophene. A preparation method for the conjugated fluorene polymer and a solar cell device containing the conjugated fluorene polymer are also provided. Due to fluorene or its derivatives and conjugated structure, the conjugated fluorene polymer exhibits an excellent light stability and thermal stability. In addition, since thiophene and benzothiadiazole groups are introduced into the main chain of the polymer, the spectral response range of the polymer is broadened.

The present invention relates to a [1,2,4]triazolo[1,5-c]pyrimidine derivative represented by formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 represents a substituted or unsubstituted aryl group Or substituted or unsubstituted aromatic heterocyclic group, R2 represents hydrogen atom, halogen, substituted or unsubstituted lower alkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aromatic heterocyclic group, na and nb are the same or different, represent an integer of 0-4, Q represents a hydrogen atom or 3,4-dimethoxybenzyl, R6 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a halogen atom or a hydroxyl group, R3 Represents: ①hydroxyl, ②hydroxyl lower alkyl, ③substituted or unsubstituted lower alkoxy, or ④selected from substituted or unsubstituted imidazo[1,2-a]pyridyl, imidazo[1,2- a]pyrazinyl, imidazo[1,2-a]pyrimidinyl, benzimidazolyl, benzothiazolyl, benzo-2,1,3-thiadiazolyl, isoxazolyl and 3-oxo Substituted-3,4-dihydro-2H-benzo[1,4]oxazine group, when R3 represents hydroxyl, hydroxyl lower alkyl or substituted or unsubstituted lower alkoxy, R4 and R5 are The same or different, represent substituted or unsubstituted lower alkyl or substituted or unsubstituted aryl, or R4 and R5 together with adjacent carbon atoms form a substituted or unsubstituted saturated carbocyclic ring, R3 represents selected from substituted or Unsubstituted imidazo[1,2-a]pyridyl, imidazo[1,2-a]pyrazinyl, imidazo[1,2-a]pyrimidinyl, benzimidazolyl, benzothiazolyl, In the case of benzo-2,1,3-thiadiazolyl, isoxazolyl and 3-oxo-3,4-dihydro-2H-benzo[1,4]oxazinyl, R4 The same as or different from R5, represents a hydrogen atom, a substituted or unsubstituted lower alkyl group or a substituted or unsubstituted aryl group, or R4 and R5 together with adjacent carbon atoms form a substituted or unsubstituted saturated carbocyclic ring.

The invention discloses a zirconium-based metal organic framework material as well as a preparation method and application thereof. The chemical formula of the zirconium-based metal organic framework material is Zr6O4 (OH) 4 (L-S) 1.2 (L-2Me) 4.8, in the formula, L-S is 2',5'-dimethyl [1,1':4',1''-triphenyl]-4,4,dicarboxylic acid, L-2Me is 4, 4'-(benzo [c] [1, 2, 5] thiadiazole-4, 7-diyl) dibenzoic acid. The zirconium-based metal organic framework material disclosed by the invention can simultaneously generate superoxide anion free radicals (O2.-) and singlet oxygen (1O2) under an illumination condition, is environment-friendly, low in price and simple to prepare, has the advantages of high catalytic activity, mild reaction conditions, convenience in operation, high substrate applicability and the like when being used for a photo-induced aerobic oxidation reaction, and has a good application prospect.

The present invention relates to the use of a combination comprising at least one host defense inducer and at least one biological control agent in a synergistically effective amount for controlling bacterial harmful organisms in useful plants. The biological control agent is selected from specific microorganisms and/or a mutant of these strains having all the identifying characteristics of the respective strain, and/or a metabolite produced by the respective strain. In a preferred aspect of the invention the host defense inducer is isotianil or a combination of isotianil and acibenzolar-S-methyl. The present invention also relates to a method for controlling bacterial harmful organisms in useful plants by treatment with a combination comprising at least one host defense inducer and at least one biological control agent in a synergistically effective amount. A further aspect of the present invention is directed to method for controlling bacterial harmful organisms in useful plants by subjecting the plants to be protected against attack by bacterial harmful organisms to two or more sequential treatment blocks.

The invention discloses application of a benzothiadiazole compound in preparation of a medicine for resisting SARS-COV-2 novel coronavirus, and belongs to the technical field of medicine. According to the present invention, the micro-mole-level benzothiadiazole compound having the structure represented by the general formula (I) is utilized to provide inhibition activity for two types of proteins, such that the anti-SARS-CoV-2 Wuhan strain virus activity is provided; according to the present invention, the benzothiadiazole compound is firstly provided to be adopted as the SARS-COV-2 novel coronavirus inhibitor, such that the new thought and the new use are provided for prevention and/or treatment of the SARS-COV-2 novel coronavirus, and the important medical research value is provided.

The invention provides a cadmium-based metal-organic framework with fluorescence recognition on Al < 3 + > and Ga < 3 + > ions and a preparation method of the cadmium-based metal-organic framework. The molecular formula of a target product is C33H22CdN6O5S. The method comprises the following steps: S1, uniformly mixing cadmium nitrate tetrahydrate, 4, 7-di (1H-benzimidazole-1-yl)-2, 1, 3-benzothiadiazole, 2, 6-naphthalic acid, N, N-dimethylformamide and methyl alcohol; S2, sealing the reaction kettle, heating, carrying out constant-temperature reaction for several hours, and cooling to obtain a yellow-green blocky crystal; and S3, washing the yellow-green blocky crystal with ethanol, and then, performing drying. Based on the strong electron withdrawing capability of the benzothiadiazole group and the strong conjugacy of the 2, 6-naphthalic acid, a new direction is indicated for preparing the luminescent metal-organic framework material, the target product efficiently recognizes aluminum ions and gallium ions through obvious fluorescence red shift, the detection limits are 4.05 mu M and 3.67 mu M respectively, and after five cycles, the fluorescent property is still kept stable, and the cadmium-based metal-organic framework has a potential application value in the fields of chemistry and material science.

The invention provides a D-A-D type organic photo-thermal small molecular material and a preparation method thereof. The D-A-D type organic photo-thermal small molecular material contains an electronwithdrawing group 2,1,3-benzothiadiazole and an electron donating group 3,6-di(thiophen-2-yl)-2,5-dihydropyrrolo[3,4-c] pyrrole-1,4-dione. The preparation method comprises the steps: substituting H ona thiophene ring of bromo-isooctane substituted 3,6-di(thiophen-2-yl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione with N-bromo-succinimide, and carrying out a reaction with 2,1,3-benzothiadiazole-4,7-bis(pinacol borate) through Suzuki reaction to obtain the target product. With the introduction of an alkyl chain on the side chain of the electron donating group, the solubility of the organic photo-thermal material in the organic solvent is improved, the problem of poor solubility of the organic polymer is overcome, and favorable light stability is achieved.

The invention provides a benzothiadiazole-TB compound as well as a synthesis method and application thereof; the structural general formula of the benzothiadiazole-TB compound is represented by a formula A, wherein R is one of hydrogen, alkoxy, hydroxyl and alkyl. The benzothiadiazole-TB compound has characteristics of large Stokes displacement, excellent luminescence property, excellent solid state luminescence, and potential of becoming an excellent OLED material; the benzothiadiazole-TB compound has a wide pH application range and can be applied to a human physiological environment; the benzothiadiazole-TB compound has effective and good response to viscosity, and has the possibility of becoming a viscosity response fluorescent probe; the benzothiadiazole-TB compound has recognition capability on Fe<3+> and is expected to become an excellent Fe<3+> fluorescent probe; and the benzothiadiazole-TB compound has a good PDT effect, can perform dyeing imaging on A549 cells, expands the variety of photosensitizers, and provides a new thought for synthesizing imaging-guided PDT photosensitizers.

The invention discloses a small molecular material with yellow mechanoluminescence of 10-membered fused ring benzothiadiazole as well as a preparation method and application of the small molecular material. The preparation method comprises the steps of 1) carrying out reduction reaction on a benzo [1, 2-b: 4, 5-b '] dithiophene-4, 8-diketone compound and sodium borohydride; 2) reacting the product in the step 1) with halogenated alkane; (3) reacting the product obtained in the step (2) with n-butyllithium and tributyltin chloride; (4) carrying out Stille coupling reaction; (5) carrying out a Cadogan reaction; and 6) reacting the product in the step 5) with halogenated alkane. The material prepared by the invention can be applied to a yellow mechanoluminescent material and a white mechanoluminescent material. The preparation method disclosed by the invention is relatively simple in process and relatively low in cost, and the prepared product has high fluorescence quantum yield in a solid state, has excellent yellow mechanoluminescence property, can generate mechanoluminescence white light emission with the CIE coordinate of (0.325, 0.346) after being doped with a blue mechanoluminescence material, and has good white light mechanoluminescence property.

The invention belongs to the technical field of preparation of covalent organic framework materials, and provides a photosensitive covalent organic framework material as well as a preparation method and application thereof. The organic monomers 4, 7-bis (4-aminophenyl)-2, 1, 3-benzothiadiazole and trialdehyde phloroglucinol are connected through a covalent bond at room temperature to form a photosensitive covalent organic framework material (COFs), and the photosensitive COFs material has an enol type structure and a ketone type structure at the same time, has excellent photosensitive property, and can generate I-type and II-type active oxygen at the same time under the irradiation of visible light. The preparation method only needs one-step simple reaction, the synthesis method is simple and convenient, the synthesis condition is mild, the consumed time is short, and large-scale synthesis is facilitated. Furthermore, the preparation method provided by the invention is easy to separate and purify, and the photosensitive COFs material can be obtained only by washing with an organic solvent.

The Arabidopsis NI16 gene was isolated in a yeast 2-hybrid screen via its interaction with the NIM1 protein and encodes a protein involved in the regulation of SAR gene expression in plants. NI16 is strongly induced in NTM1-overexpressing plants treated with benzo(1,2,3)thiadiazole-7-carbothioic acid S-methyl ester (BTH). The nucleic acid sequence of the Arabidopsis NI16 promoter is disclosed herein.

The invention discloses copolymers containing fluorene, anthracene and diazosulfide units, a preparation method of the copolymers, and an application of the copolymers. The copolymers are represented by a molecular general formula (I). In the formula, n is a natural number from 1 to 500. m is a natural number, wherein 1<=m<=20. x, y are positive real numbers, and x+y=1. R1 and R2 are selected from hydrogen atom, halogen, cyan, optionally substituted or non-substituted C1 to C40 alkyl, aryl or heteroaryl. R3 is selected from hydrogen atom, cyan, optionally substituted or non-substituted C1 to C40 alkyl, C1 to C40 alkoxy, C6 to C40 aryl, C6 to C40 aralkyl, or C6 to C40 aryl alkoxy. The copolymers containing anthracene and diazosulfide units have high solubility, high carrier mobility, high light absorbance, wide light absorbing scope, and improved utilance of sunlight. The preparation method of the copolymers is easy; the yield is high; and the processes are easy to operate and to control.