The invention discloses a center chirality-axial chirality electron deficiency diphosphine ligand as well as synthesis and application thereof. The electron deficiency diphosphine ligand is designed and synthesized by the following steps: by basing bis(diethyl phosphate) as a compound, reducing the bis(diethyl phosphate) into a phosphine hydride, then carrying out synthesis on the phosphine hydride to obtain a phosphine chloride compound, and finally, carrying out reaction on the phosphine chloride compound and an aryl grignard reagent to obtain the center chirality-axial chirality electron deficiency diphosphine ligand. After being coordinated with metallic rhodium, the ligand can be effectively applied to 1,4-addition reaction of alpha,beta-unsaturated carbonyl compounds. The center chirality-axial chirality electron deficiency diphosphine ligand is practical, a catalyst is commercially available, and the reaction condition is mild.