The invention provides a manufacturing process of an LED bulb with a driver arranged inside. The manufacturing process is characterized in that the process comprises the assembling procedures of connection of a packaging column and a special driving power source, point butt-joint of a lamp filament, testing, sealing and exhausting, gluing, lamp base feeding, aging testing and packaging, and the driving power source is located in a bulb shell. The LED bulb comprises the driver and the shell, the driver is fixed in the shell which is composed of a shell cover and a packaging panel, identical packaging column mounting holes are formed in the center of the driver, the center of the shell cover and the center of the packaging panel correspondingly, and the packaging column mounting holes are in clearance fit with the packaging column; and two electrode wire holes are formed in the two sides of the packaging column mounting hole in the shell cover correspondingly, the packaging panel is an integrated circuit board, input electrode wires of the driver penetrate through the electrode wire holes, output conductor wires of the driver are connected with the packaging panel, and electrode branch wires are fixed to the upper end of the packaging panel. The assembling process of the LED bulb comprises the steps of connection of the driver and the packaging panel, shell cover installation, testing, and power source assembling. According to the manufacturing process, the mechanization degree is high, the labor intensity is low, product quality is high and stable, the cooling effect is good, and the service life is long.