The invention discloses continuous casting crystallizer mold powder of a sheet billet at a high casting speed. The mold powder comprises chemical components in percentage by weight as follows: 34%-44% of CaO, 2%-8% of Al2O3, 20%-30% of SiO2, 1%-9% of MgO, 5%-15% of F, smaller than or equal to 6.5% of Na2O, smaller than or equal to 5% of K2O, smaller than or equal to 6% of Li2O and the balance of carbon and uncontrollable impurities. Content of CaO in the mold powder is high, content of SiO2 in the mold powder is low, accordingly, the degree of purity of molten steel can be improved, simultaneously, MgO and CaO in the mold powder are alkaline earth metal oxides, Li2O, Na2O and K2O are alkali metal oxides, the melting temperature is low, the fluxing effect is achieved, the usage amount of a fluxing agent can be reduced, the probability of various crystal precipitation is reduced, so that the glass performance of the mold powder is improved, and the mold powder has a good lubrication effect at the high casting speed; accurate control on F content meets requirements of surface quality at the high casting speed, and lubrication is improved by means of an appropriate amount of Al2O3; and the mold powder can meet technological requirements of continuous casting of medium carbon steel such as SS400, Q345 and the like, moreover, the mold powder components have stable performance, and sequence casting can be realized.