75results about How to "Little change in pH" patented technology

The invention belongs to the technical field of biomasses, particularly provides a method for preparing 5-hydroxymethylfurfural by utilizing biomass sugar. The method comprises the following steps of taking biomass sugar as a raw material, catalyzing the raw material under a water phase condition in acid, neutral or alkali buffering systems, and obtaining 5-hydroxymethylfurfural. The method provided by the invention is applicable for multiple kinds of raw material sugars, the wide of the initial concentration of the sugar is wide, the heating way is flexible, the temperature range is wide, and the buffering system is versatile; and moreover, the operation is simple and convenient, the equipment is simple, the energy is saved, the post-treatment is convenient, and the rate of conversion and selection are higher. 5-hydroxymethylfurfural is one of the important platform compounds capable of being obtained from biomasses to substitute the petrochemical products, can perform oxidation reaction, reduction reaction, halogenation reaction, polyreaction and the like, and also can be used as the intermediate for fine chemistry industry, pharmacy and furyl polymer, thereby having great economic value and wide application prospect. The method provided by the invention can realize large-scale industrialization production.

The invention belongs to the field of pharmaceutical preparations, and particularly relates to a novel injection of an adenosine A2A receptor agonist Regadenoson and a preparation method of the injection. The Regadenoson injection is prepared from the main drug Regadenoson, a cosolvent, an antioxidant, a stabilizer and an isoosmotic adjusting agent, wherein the cosolvent is selected from L-histidine or a combination of L-histidine and other amino acid, the stabilizer is selected from a combination of tris-hydroxymethyl aminomethane and hydrochloric acid, and sodium chloride is preferably selected as the isoosmotic adjusting agent. According to the injection, propylene glycol and phosphate buffer salt are prevented from being used, a surfactant solubilizer is not adopted, the formula and the process are simple, the injection is suitable for industrialized large-scale production, and the stability is significantly improved after high-temperature sterilization and long-term storage.

The invention belongs to the field of separation and recovery of cobalt and nickel, and more specifically relates to a method for extracting and separating cobalt and nickel that reduces co-extraction. This separation method fully combines the characteristics and requirements of cobalt-nickel extraction and separation, and proposes to use the buffer mechanism to maintain the pH of the aqueous phase in the cobalt-nickel extraction process in the optimal pH range of cobalt instead of the optimal pH range of nickel, and at the same time, the extraction process Control and adjust the key process parameters in the medium, maintain the buffering capacity of the buffer solution, and reduce the co-extraction of nickel, thereby solving the problem of severe nickel co-extraction due to the increase in the pH of the feed solution during the extraction process of the existing technology when extracting and separating cobalt and nickel, which eventually leads to Technical problem of reduced cobalt-nickel separation efficiency.