11 results about "Cholestanols" patented technology

Since it separates into at least an emulsion layer and an aqueous layer during standing, it has excellent aesthetic properties. When used, it can be uniformly redispersed by gently shaking, so it also has excellent usability. In addition, it has good storage stability, and further provides a multi-layer cosmetic excellent in the softness of the back skin. 【Means for Solving the Problem】 The following components (A) to (G): (A) Phospholipid (B) Cholesterol and / or phytosterol (C) Phosphoric acid-based surfactant (D) Oil agent (E) Sodium polyaspartate (F) Water-swelling clay mineral (G) Water A multi-layer cosmetic containing the above components.

This invention discloses a *Lactobacillus plantarum* YBE2 and its applications. The *Lactobacillus plantarum* provided by this invention, which produces a high amount of extracellular polysaccharides primarily composed of rhamnose, can simultaneously degrade different types of bile salts, including specifically hydrolyzing glycocholic acid. It also exhibits cholesterol-lowering and acute inflammation-relieving effects. Furthermore, *Lactobacillus plantarum* YBE2 can reduce fat deposition in the abdomen of caged broilers, increase intramuscular fat, promote fatty acid deposition in muscles, and reduce plasma total bile acids, triglycerides, and low-density lipoprotein cholesterol. This significantly improves lipid metabolism and muscle quality in poultry, and can be widely applied in caged broiler farming to promote healthy poultry farming and improve farming efficiency.

The invention discloses a preparation method of 7-p-toluenesulfonyl hydrazone-3-cholesteryl acetate. The 7-p-toluenesulfonyl hydrazone-3-cholesteryl acetate The invention provides a preparation method of a compound shown in a formula I. The preparation method comprises the following step: in an aprotic solvent, in the presence of acid, anhydride and an adsorbent, a compound shown in a formula II and a compound shown in a formula III are subjected to a reaction shown in the specification to obtain the compound shown in the formula I. The method is mild in reaction condition, high in reaction speed, high in conversion rate and few in side reaction, and the compound shown in the formula I and with the purity larger than or equal to 98.5% can be obtained; the obtained crystal particles are large in particle size and high in filtering speed; the method has good process conditions and is suitable for large-scale industrial production.

Disclosed in the present invention are a kit for detecting 15 bile acid profiles and three bile acid precursors in serum simultaneously and a detection method therefor. The 15 bile acid profiles comprise: cholic acid, deoxycholic acid, chenodeoxycholic acid, ursodeoxycholic acid, lithocholic acid, glycocholic acid, glycodeoxycholic acid, glycochenodeoxycholic acid, glycoursodeoxycholic acid, glycolithocholic acid, taurocholic acid, taurodeoxycholic acid, taurochenodeoxycholic acid, tauroursodeoxycholic acid and taurolithocholic acid; and the three bile acid precursors comprise: 3α,7α-dihydroxycoprostanic acid, 3α,7α,12α-trihydroxycholestanoic acid and 7α-hydroxy-4-cholesten-3-one. The kit and detection method of the present invention enable the simultaneous and accurate detection of the 15 bile acid profiles and the three bile acid precursors, with a short detection time and a high detection accuracy. This, to a certain extent, meets the clinical need for assessing the enterohepatic cycle composed of the biliary system, intestines, portal venous circulation and hepatocytes.

The invention discloses a preparation method of a fluorine bone triol intermediate, which comprises the following steps: (20S)-3beta-acetoxy-20-methyl-21-iodo-pregna-5-ene as shown in a formula II is taken as a raw material, and 26, 26, 26, 27, 27, 27-hexafluoro-25-hydroxycholesterol is prepared through four steps of reaction, namely coupling, ester hydrolysis, trifluoromethyl substitution and trifluoromethyl addition, and the reaction formula is as shown in the specification. The method has the advantages of simple process, cheap and easily available reagents, and suitableness for industrial production.

The invention discloses a preparation method and application of a terpene alcohol body of permeation-enhancing conopeptide, and belongs to the technical field of cosmetics. The terpene alcohol body for enhancing the permeation of conopeptide provided by the invention comprises the following components in percentage by mass: 1 to 15 percent of phospholipid, 0.1 to 10 percent of lysophosphatidylcholine, 0.5 to 3 percent of cholesterol, 0.01 to 2 percent of terpene, 2 to 50 percent of polyhydric alcohol, 0.001 to 1 percent of conopeptide and the balance of deionized water. On the basis of molecular docking, phospholipid and lysophosphatidylcholine with specific types and proportions are screened and used for entrapment of conopeptide, and terpene alcohol with stable structure and conopeptide entrapment efficiency greater than 90% is obtained; according to the preparation method, a terpenol body is added, a lysophosphatidylcholine, terpene and polyhydric alcohol ternary permeation enhancing system is uniformly integrated to the terpenol body, finally, the transdermal capacity of conopeptide is remarkably enhanced, the transdermal depth of conopeptide is promoted, the intradermal cumulant of conopeptide is increased, and a foundation is laid for achieving the effect of the conopeptide in cosmetics.

The invention relates to the field of organic synthesis, in particular to a method for synthesizing dihydrocholesterol by catalytically hydrogenating cholesterol, cholesterol is used as a raw material, hydrogenation reaction is performed in the presence of a hydrogen donor and a Pd / CuO-Al2O3 catalyst to generate dihydrocholesterol, direct use of hydrogen as the raw material is avoided, safety is good, the green chemical industry trend is met, reaction conditions are mild, and the method is suitable for industrial production. The reaction temperature is low, the reaction time is short, and the industrial production application prospect is good.

The invention relates to the technical field of food and feed additives, and discloses application of a tea polyphenol preparation in reduction of egg cholesterol. The tea polyphenol preparation comprises high-purity tea polyphenol, a phospholipid complex, phytosterol, bile acid binding resin and a microcapsule wall material. By limiting the purity and component composition of tea polyphenol, a phospholipid-mediated nano delivery system is constructed, a dual mechanism of bile acid adsorption and phytosterol competitive absorption is introduced, and the stability of active components in the feed processing and digestion process is guaranteed by adopting a microcapsule technology; the technical scheme which is definite in component, clear in action path, convenient to use and repeatable in effect is formed, the defects that in the prior art, multiple components are mixed, the mechanism is unknown, operation is tedious, raw materials are limited and the like are effectively overcome, and reliable technical support is provided for industrial production of the low-cholesterol functional eggs.

The invention discloses an LCP special fiber and a preparation method thereof, and relates to the technical field of LCP fibers. The LCP special fiber is prepared by mixing LCP resin, a vinyl fibrous filler, an unsaturated monomer and a photoinitiator, carrying out melt jet direct spinning, rapid cooling and winding, and then carrying out ultraviolet irradiation curing, the LCP resin is prepared by carrying out hydrosilylation on cholesterol oleate, an acylamino-containing monomer and hydrogen-containing polymethylsiloxane to obtain a liquid crystal polymer, and the liquid crystal polymer is prepared by carrying out melt jet direct spinning, rapid cooling and winding. An amide group and a smooth Si-O-Si chain segment are introduced into a polymer molecule and cooperate with long-chain alkyl of cholesteryl ester, so that the flexibility, the mechanical property and the bending resistance of the fiber are remarkably improved; a three-dimensional network is formed through filler enhancement and illumination curing, and a rapid cooling process is combined, so that the obtained LCP special fiber has high strength, high wear resistance, excellent bending resistance and low after-shrinkage rate.

The invention discloses a production method and application of a bile acid and Chinese herbal medicine combined feed additive. The additive is prepared from the following raw materials in parts by weight: 30-50 parts of rhizoma alismatis, 15-25 parts of hawthorn, 10-20 parts of radix bupleuri, 5-15 parts of an artemisia apiacea extract, 2-8 parts of berberine, 5-15 parts of pericarpium citri reticulatae, 10-20 parts of poria cocos and 5-10 parts of liquorice. Based on the compatibility theory of'monarch, minister, assistant and guide 'of traditional Chinese medicine, various Chinese herbal medicine active ingredients such as rhizoma alismatis, hawthorn, radix bupleuri, artemisia apiacea extract, berberine, pericarpium citri reticulatae, poria cocos and liquorice are selected and scientifically formulated, all the ingredients are clear in division of labor and have a synergistic effect, the rhizoma alismatis serves as the monarch, and cholesterol metabolism is directly regulated and controlled; multi-target synergistic interaction of promoting bile acid synthesis, inhibiting inflammatory response, remodeling intestinal microecology, repairing intestinal liver circulation steady state and the like is realized, the action mechanism is clear, and the effect is superior to that of a single component or a simple mixture.