61 results about "Glycine Hydrochloride" patented technology

An amino acid broad-spectrum medicinal fertilizer without environmental pollution contains the mixture of copper zine manganese iron magnesium salts of mixed amino acid (13-20 wt.%), glycine hydrochloride (2-6), kurarinone (0.1-1), mangostin (0.06-0.6), veratrine (0.3-1), bioactive synergist (0.06-0.6), Chinese medical stone extract (1.5-2.5), surfactant (0.5-5) and filler (the rest). It has bothantibacterial and nutritive functions for raised yield and improvement quality of crops.

A process for preparing N,N-Dimethyl Glycine Hydrochloride, comprises treating a chloroacetic acid with aqueous dimethylamine, and then dropping by hydrochloric acid to obtain N,N-dimethyl glycine as well as its hydrochloride salt, wherein decompression process is utilized to assure the product purity and active carbon is employed for cost saving aspect.

It is provided a pharmaceutical composition stably containing ghrelin or its derivative, which is an endogenous growth hormone secretagogue (GHS) to a growth hormone secretagogue-receptor (GHS-R), comprising a aqueous solution containing the ghrelins having pH range of 2 to 7, wherein the aqueous solution having pH range of 2 to 7 is a buffer solution, especially, glycine hydrochloride buffer, acetate buffer, citrate buffer, lactate buffer, phosphate buffer, citric acid-phosphate buffer, phosphate-acetate-borate buffer or phthalate buffer, and the concentration of the ghrelins in the solution is from 0.03 nmol / mL to 61 μmol / mL.

The invention discloses a cultivation method for a yellow peach tree. According to the method, cultivation and culture are reasonably carried out for nutrient elements needed by the yellow peach tree planting and growth habits, the large number nutrient elements needed by growing of the yellow peach tree can be guaranteed through application of the base fertilizer, and shaping and clipping are matched. The nutrition special fertilizer for fertilization management comprises 90-150 parts of bio-organic fertilizer, 20-30 parts of urea, 15-30 parts of bean pulp, 1-2 parts of ammonium bicarbonate, 25-35 parts of calcium superphosphate, 10-15 parts of diamine sulfate, 10-15 parts of monopotassium phosphate, 3-4 parts of zinc sulfate, 1-3 parts of ammonium molybdate and 9-12 parts of glycine hydrochloride. Flower and fruit management is carried out. By means of disease and pest preventing and treating, the yellow peach tree can be protected against hurt of diseases and pests while the yellow peach tree grows. The yellow peach tree planted through the method has the beneficial effects of being high in yield and good in quality.

The invention relates to a one-step preparation method of amphoteric guar gum, belonging to the technical field of guar gum modification. The preparation method disclosed by the invention comprises the following steps: (1) adding a certain amount of chloroacetic acid to an amine aqueous solution at room temperature, and controlling the pH value to be 7-10 for reaction to prepare glycine hydrochloride; (2) dispersing the glycine hydrochloride and low-carbon alkylene oxide in a weak polar or non-polar solvent to be subject to a reaction at 50-70 DEG C to prepare an amphoteric intermediate; (3) adding raw guar gum powder to the weak polar or non-polar solvent at normal temperature, adding a basic catalyst to carry out basic catalysis; and (4) adding the amphoteric intermediate to be subject to an etherification reaction at a pressure of 0.05-0.33MPa, and collecting the amphoteric guar gum product from the reaction product. The prepared product has high ion interference resistance and salinity tolerance. Besides, the product can be used as a retention and drainage aid for paper making and achieves obvious effects and high paper formation. When the product is used as an intensifier, the dry strength of paper can be obviously improved, and the softness of paper can not be reduced.

The invention discloses a bio-based hemodialysis membrane and a preparation method thereof. The hemodialysis membrane is prepared from polylactic acid, laminarin, thiolated chitosan, silk fibroin, sodium ascorbyl phosphate, cellulose acetate, dithiothreitol, stachyose, betulin caffeate, ammonium persulfate, ferulic acid, hydroxyethyl starch, N-benzyl glycine hydrochloride, deoxycholic acid, polyhydroxyalkanoate, hexamethylenediamine, hyaluronic acid, benzoperoxide and dimethyl sulfoxide. According to the prepared hemodialysis membrane, the tensile strength is not lower than 7.0 MPa, the transmittance of urea is higher than 86%, the transmittance of beta2 microglobulin is higher than 66%, the rejection rate of macromolecular protein is higher than 95%, the biocompatibility is good, coagulation, thrombus, inflammation, poisoning and other adverse reactions do not exist, and an application prospect is wide.

The invention relates to an acetate acid free hemodialysis agent of bicarbonate. The hemodialysis agent is composed of constituent A and constituent B, constituent A: sodium chloride 77%-94%, potassium chloride 0%-4%, calcium chloride 2%-6%, magnesium chloride 1%-3%, glycine hydrochloride 3%-10%. constituent B: sodium bicarbonate 65%-100%, sodium chloride 0%-35%.

The invention belongs to the field of textile finishing agents and particularly relates to a microcapsule for a textile after-finishing as well as a preparation method and application thereof. The microcapsule consists of a core material and a capsule wall according to the weight ratio of (0.2-0.6):1, wherein the core material comprises 10-20 parts by weight of plant essential oil and 0.2-1 part of L-methionylglycine hydrochloride; the capsule wall is prepared from starch octenylsuccinate, nano-microcrystalline celluloses and casein sodium according to the weigh ratio of 1:(0.1-0.3):(0.3-0.8). The microcapsule provided by the invention has good mechanical strength and has the advantages of being natural, safe and degradable; the microcapsule has good affinity with a textile product; a test shows that the textile product finished by the microcapsule is lasting in fragrance, the repelling rate reaches 89 percent, and a mosquito repelling effect is very strong.

The invention discloses an improved method for preparing glycine ethyl ester hydrochloride. The method includes the steps of putting glycine, ethyl alcohol and hydrogen chloride according to a certainratio for salinization and esterification, adding dehydrant for evaporating water, conducting cooling, crystallizing, centrifugal separating and drying to obtain a product, adding a certain volume ofwater to a three-element system composed of the evaporated dehydrant, ethyl alcohol and water for standing and phase separating, directly recycling a phase layer of the dehydrant, conducting phase separating to obtain a water phase for recovering ethyl alcohol for use, and recycling a centrifugal mother solution for material putting. After salinization and esterification of glycine, the content of water in esterification liquid is reduced, glycine hydrochloride can continue to be esterified into glycine ethyl hydrochloride in the rectification process, the generated water is taken away at thesame time, and the product conversion rate is increased; the mother solution obtained after crystallization and centrifugation is recycled without distillation, neutralization and rectification treatment of each batch, the treatment amount of leftovers and waste salt is reduced, and energy consumption is also reduced. Meanwhile, the content of glycine hydrochloride is reduced, so the product quality is improved.

The invention relates to a glycine and an application of an acid salt thereof in preparation of herbicide-glyphosate, and in particular relates to an application of glycine hydrochloride and glycine methyl ester hydrochloride in preparation of the herbicide-glyphosate.

The invention discloses a method for preparing a binder for waterproof monofilament fishing nets. Add N-octyldiaminoethylglycine hydrochloride, mix and stir evenly; (3) After adding the additive solution to the mixture prepared in step (2), slowly add a strong oxidant solution to it, and reduce the temperature of the reactant to After rising to 60-70°C, heat preservation treatment for 15-30 minutes, filter to obtain the filter residue, clean the filter residue with deionized water, and obtain the required binder. The adhesive for monofilament fishing net provided by the present invention has low raw material price, simple manufacturing method, and the prepared adhesive has strong cohesive force and can be cured at room temperature by itself, so that the net knot can achieve sufficient strength, and Strong water resistance, will not swell in water, will not affect the transparency of monofilament fishing nets, and have no color difference in water.

The invention discloses a method for detecting N-tertbutyl glycyl acyl hydrochloride in tigecycline. The invention further discloses a method for detecting N-tertbutyl glycine hydrochloride in tigecycline. The methods are used for detecting the N-tertbutyl glycyl acyl hydrochloride and the N-tertbutyl glycine hydrochloride in tigecycline, are accurate and reliable in detection result, strong in specificity and short in detection time; and moreover a good separation degree of the N-tertbutyl glycyl acyl hydrochloride and the N-tertbutyl glycine hydrochloride is achieved, so that the possibility in comprehensively detecting the impurities in a tigecycline product, controlling the product quality and ensuring the medicine security is provided.

The invention belongs to the field of medicine and chemical industry, and discloses a preparation method of glucosamine sulfate potassium salt. The preparation method comprises the following steps: adding lactic acid glycine hydrochloride and hydrochloric acid into chitin powder, stirring and mixing, and filtering to obtain a filtrate; heating, preserving heat, dropwise adding hydrochloric acid, stirring, cooling, decoloring the solution, concentrating, washing and drying to obtain glucosamine hydrochloride; adding a potassium sulfate aqueous solution, heating, adding an organic solvent, cooling to 25 DEG C to 35 DEG C, fully reacting, cooling, crystallizing, centrifuging to obtain a white crystal, and drying to obtain the glucosamine sulfate potassium salt. According to the preparation method, the high-purity glucosamine hydrochloride is obtained firstly, then the potassium sulfate aqueous solution is added to prepare the glucosamine sulfate potassium salt, and the glucosamine sulfatepotassium salt of which the purity reaches up to 99.95% or more is obtained through crystallization purification and separation, so that the whole technical process is simple, low in cost, environmentally-friendly and economical, and the preparation method is suitable for large-scale popularization and application.

The invention discloses a preparation method of a thermal insulation color steel tile. The method comprises the following steps that 1, after the surface of the color steel tile is cleaned thoroughly,a modified solution is sprayed to the surface; 2, after asphalt s heated to 170-180 DEG C, basalt fiber and polycaprolactam powder are mixed to be uniform, the mixture is added into a high-speed shearing instrument to perform high-temperature off-speed cutting, and a thermal insulation additive is obtained; 3, methylacrylic acid, diglyeidyl adipate, dimeric linoleic diglycidylester, stearyl methacrylate and potassium persulfate are mixed to be uniform, then, a heating reaction is performed, and a copolymer emulsion is obtained; 4, the copolymer emulsion, the thermal insulation additive, N-octyl diamine glycine salt, aluminium isopropoxide and Isopropyl oxydistearate acyl aluminate are mixed to be uniform, and then the color steel tile coating is obtained. The obtained thermal insulation color steel tile has the excellent ageing resistance, corrosion resistance and waterproof performance, and has the excellent thermal insulation effect.

The invention belongs to the field of pharmaceutical chemicals and discloses a method for preparing glucosamine sulfate and sodium chloride double salt. The preparation method comprises the followingsteps: adding lactic acid glycine hydrochloride and hydrochloric acid into chitin powder, performing stirring and mixing, and performing filtering to obtain filtrate; heating the filtrate, performinginsulation, dropwise adding hydrochloric acid into the solution, stirring the mixture, cooling the mixture, and performing decoloring, concentrating, washing and drying to obtain glucosamine hydrochloride; adding a sodium carbonate aqueous solution into the glucosamine hydrochloride, performing heating, adding acetone into the mixture, performing cooling and stirring, adding sulfuric acid into themixture, performing stirring, cooling completely reacted materials to 5-15 DEG C, performing crystallization, drying centrifuged crystals to obtain the glucosamine sulfate and sodium chloride doublesalt. The method has a safe and controllable production flow, the glucosamine sulfate and sodium chloride double salt has high purity and high stability, the finished product has high quality, and thedefects that pure glucosamine sulfate has high moisture absorption, is not stable and is not suitable for medicinal application can be overcome.

The invention relates to a process for the preparation of anagrelide, and for the preparation of intermediates for use in preparing anagrelide. The invention also relates to the intermediates per se, in particular compounds of Formula (V):where R constitutes a suitable leaving group, which may not be hydrogen. The R group may be selected from: (i) —SiR13, (ii) —CH2Ar, (iii) —COOR2, and (iv) sulfonates such as —SO2R3.

The invention provides juice jelly with effects of beautifying and losing weight. The juice jelly is prepared from the following raw materials in parts by weight: 16 to 22 parts of mixed fruit juice, 1 to 5 parts of gelatin, 1 to 5 parts of carrageenan, 0.5 to 4 parts of L-methionylglycine hydrochloride, 0.5 to 2 parts of calcium lactate, 5 to 12 parts of sugar and 60 to 75 parts of water. The invention belongs to the technical field of food processing; the juice jelly does not contain a preservative and is high in content of fruit juice; the prepared juice jelly has the advantages of strong greengage flavor, good shape stability, good mouthfeel, easiness in digestion and absorption, long shelf life and the like; the juice jelly has the effects of beautifying and losing weight, and is good in safety.

The invention discloses a method for preparing chiral alpha-alkyl substituted glycine hydrochloride. The method comprises steps of: selecting commercialized or easily prepared tert-butyl glycinate as an initial raw material; inducing alpha position chiral alkyl substitution through a chiral adjuvant (S) camphor; carrying out chemical split to obtain alpha-alkyl substituted glycine ester; and finally hydrolyzing to obtain optically pure alpha-alkyl substituted glycine hydrochloride. R represents C1-C12 saturated or unsaturated alkyl, or C1-C12 saturated or unsaturated alkyl substituted phenyl. The method uses cheap and easily available raw materials, has high reaction yield, stable technical condition, simple operation and no pollution; the obtained product has an optical purity greater than 99%; therefore, the invention provides a new idea and method for large-scale production of amino acid with high chiral purity.

The invention discloses a preparation method for a low temperature resistant geogrid. The preparation method comprises the following operating steps: (1) preparing a low temperature resistant additive, namely, placing aluminium oxide, 3-hydroxyl-1-adamantaneacetic acid, N,N-di(octyl aminoethyl) glycine hydrochloride, titanium dioxide and tungsten disulphide into a ball grinding mill, mixing at a high speed to prepare the low temperature resistant additive; (2) mixing HDPE (High-Density Polyethylene), an antioxidant DLTP (Dilauryl Thiodipropionate), tetrabromo bisphenol S, heptamethylnonane and dinonyl phthalate, placing the mixture in a high-speed mixing machine, mixing at a high speed, adding the low temperature resistant additive into the high-speed mixing machine, and continuing mixing; (3) placing the mixture which is obtained in the step (2) into an extruding machine for melting and extruding to prepare a plate; (4) punching the plate to obtain mesh holes through a punching machine; (5) performing unidirectional stretching and subsequent further horizontal stretching on a porous plate after the porous plate is heated through a preheating device so as to form a unidirectional or bidirectional stretched grid. The geogrid prepared by the preparation has good low temperature resistance, and can work normally in a low temperature environment and ensure the quality of a product.

The invention belongs to the field of pharmaceutical chemicals, and discloses a purification and separation method of N-acetyl-D-glucosamine. The purification and separation method of the N-acetyl-D-glucosamine comprises the following steps: adding lactic acid glycine hydrochloride and hydrochloric acid into chitin powder, performing mixing, and performing filtering to obtain a filtrate; performing heating, adding hydrochloric acid dropwise, performing stirring, performing cooling, and performing decoloring to obtain D-glucosamine hydrochloride; adding an ethanol solution of sodium ethoxide, and performing filtering to obtain a free D-glucosamine solution; adding acetic anhydride to obtain a solution containing the N-acetyl-D-glucosamine; and performing concentration, performing cooling, performing crystallizing, performing filtration to obtain an N-acetyl-D-glucosamine crude product, performing soaking by using absolute ethyl alcohol, performing stirring, performing filtration, and performing drying to obtain the high-purity N-acetyl-D-glucosamine. According to the method, the N-acetyl-D-glucosamine with the purity of 99.95% or above can be obtained, the technological process is simple, the post-treatment is easy to realize, the cost is low, the used alcohol solvent can be recycled, and the method is environmentally friendly, economical and suitable for large-scale promotion and application.

The invention discloses a method for preparing a flame-retardant flexible freight bag. The method comprises the following operating steps: (1) uniformly mixing melamine cyanurate, sodium molybdate dihydrate, glycine N-bis(octylaminoethyl)hydrochloride and polyvinyl imidazol, adding the mixture into a ball mill, performing ball milling for 2-3 hours, and drying to obtain a flame retardant; and (2)uniformly mixing polypropylene resin, the flame retardant, N-acetylthiourea and mixed additives, adding the mixture into an extruder, performing melt spinning, braiding into a suspender and base clothby a weaving machine, cutting, and sewing, thereby obtaining the flame-retardant flexible freight bag. The preparation method of the flame-retardant flexible freight bag provided by the invention issimple to operate and low in cost, and the prepared flame-retardant flexible freight bag has excellent mechanical property and high filament strength, does not cause a breakage phenomenon after braided molding, particularly has excellent flame-retardant property, and can prevent fostering of the fire when the fire happens.

The invention discloses a special prevention and cure agentia for stalk rot of money trees and a use method thereof. The agentia comprises the following components in parts by weight: 10-14 parts of 72% Kelu powder, 11-14 parts of 69% acrobat-MZ, 4-8 parts of herba houttuyniae infusion, 3-8 parts of tripterygium wilfordii infusion, 10-15 parts of magnesium sulfate, 4-8 parts of pepper water, 0.2-0.6 part of carboxymethyl cellulose, 2-3 parts of glycine hydrochloride, 2-3 parts of astragalus polysaccharide and 80-100 parts of water. All the components are prepared and mixed according to a proportion, and then are uniformly agitated so as to obtain the prevention and cure agentia; a 800-1,000 times diluent liquid of the prevention and cure agentia is sprayed to the environment of damaged plants for 2-4 times, and the time interval of each time of agentia application is 5-8 days. The special prevention and cure agentia has good prevention and cure effects, is simple in preparation process and convenient to use, reduces the use amount of agricultural pesticide, relieves pollution to the environment, and facilitates the ecological equilibrium.

The invention provides a preparation method of 2-n-butyl-4-chloro-5-formylimidazole. The preparation method comprises the following steps of using pentanimidamide hydrochloride and tert-butyl glycine hydrochloride as initial raw materials to react, so as to obtain (1-imido amyl)tert-butyl glycinate; performing deprotection, ring closing, chlorinating and vilsemier reaction, and recrystallizing, so as to obtain the 2-n-butyl-4-chloro-5-formylimidazole. The preparation method has the advantages that the price of raw materials is low, the obtaining is easy, the cost is low, the content of impurities is low, and the purity is high; the organic solvent used in the preparation process can be recycled, the pollution is little, the environment-friendly effect is realized, and the preparation method is suitable for industrialized large-scale production.

The invention discloses dioctyl salt wettable powder and a preparation method and application thereof. The dioctyl salt wettable powder comprises 12 mass percent of dioctyl diethylenetriamine glycine hydrochloride and 4 mass percent of oxytetracycline hydrochloride. The dioctyl salt wettable powder of the invention has a good preventing and controlling effect on pectobacterium chrysanthemi diseases, wherein the preventing and controlling effect is over 89 percent in pot experiments, and the preventing and controlling effect is over 71 percent in field experiments; and the powder has the advantages of low toxicity, no residue and no influence on ecological environment.

The invention discloses a special prevention and cure agentia of the late blight of money trees and a use method thereof. The special prevention and cure agentia comprises the following components in parts by weight: 10-14 parts of cyazofamid, 3-8 parts of oligosaccharins, 3-7 parts of cuppric nonyl phenolsulfonate, 10-14 parts of 25% metalaxyl, 3-10 parts of 40% asomate, 10-16 parts of 40% phosethyl manganese zinc wettable powder, 10-14 parts of camphor infusion, 3-5 parts of glycine hydrochloride, 1-3 parts of plant essence, 4-10 parts of alcohol and 120-140 parts of water. All the components are prepared and mixed according to a proportion, and then are uniformly agitated so as to obtain the prevention and cure agentia; a 800-1,000 times diluent liquid of the prevention and cure agentia is sprayed to the environment of damaged plants for 2-4 times, and the time interval of each time of agentia application is 5-8 days. The special prevention and cure agentia has good prevention and cure effects, is simple in preparation process and convenient to use, reduces the use amount of agricultural pesticide, relieves pollution to the environment, and facilitates the ecological equilibrium.

The invention discloses a preparation method for a deodorization sterilization sheet used for sterilizing infectious medical waste. The preparation method comprises the following operation steps: (1)preparing sodium aluminate solution, then, regulating the pH (Potential of Hydrogen) of the solution, heating mixed liquid, carrying out thermal insulation reaction, cooling to room temperature, carrying out centrifugation to obtain sediments, and preparing a water insoluble carrier; (2) after polyethylene glycol 6000 is heated and fused, adding sodium lignin sulfonate, sodium bicarbonate and N-octyl diamine ethyl glycine hydrochloride into the polyethylene glycol 6000, cooling to room temperature, and smashing to obtain a water-soluble carrier; (3) evenly mixing the water insoluble carrier, the water-soluble carrier, citric acid and sodium dichloro cyanurate, slowly adding absolute ethyl alcohol and 4-dodecalactone into the mixture to be evenly stirred, adding into a granulator to be granulated and dried, and pressing to obtain the deodorization sterilization sheet. The deodorization sterilization sheet prepared with the preparation method has the advantages of obvious sterilization effect, no odorous pungent smell, and odorous smell in the infectious medical waste can be effectively prevented from emitting.

It is provided a pharmaceutical composition stably containing ghrelin or its derivative, which is an endogenous growth hormone secretagogue (GHS) to a growth hormone secretagogue-receptor (GHS-R), comprising a aqueous solution containing the ghrelins having pH range of 2 to 7, wherein the aqueous solution having pH range of 2 to 7 is a buffer solution, especially, glycine hydrochloride buffer, acetate buffer, citrate buffer, lactate buffer, phosphate buffer, citric acid-phosphate buffer, phosphate-acetate-borate buffer or phthalate buffer, and the concentration of the ghrelins in the solution is from 0.03 nmol / mL to 6 μmol / mL.

The invention discloses a treatment process for leftover materials generated in a glycine ethyl ester hydrochloride preparation process. The process comprises the steps of reacting glycine with absolute ethyl alcohol in the presence of hydrogen chloride, crystallizing and separating a reaction product to obtain mother liquor, and adding alkali to hydrolyze the mother liquor. The treatment method provided by the scheme for the leftover materials generated in the glycine ethyl ester hydrochloride preparation process is particularly suitable for treating the leftover materials after repeated treatment and recovery. Through the treatment, residual glycine ethyl ester hydrochloride, glycine hydrochloride and other hydrolyzable byproducts are hydrolyzed into glycine and the like by adding alkali, then the pH value is adjusted to be close to an isoelectric point of glycine, glycine is separated out, glycine is obtained through separation, and ethanol generated through hydrolysis is recycled through distillation. By means of the scheme, the generation amount of leftover solid waste can be greatly reduced.

The invention discloses a preparation method of an ethyl chitosan film. The preparation method comprises fully dissolving self-made ethyl chitosan in a glycine hydrochloride aqueous solution with a concentration of 1-5% to obtain an ethyl chitosan stock solution with a concentration of 1-5wt%, and orderly carrying out extruding filtration, standing deaeration, spin-coating on a glass plate, drying at a constant temperature of 40 DEG C at constant humidity of 50%, immersion in anhydrous ethanol for 1-5h, film uncovering, film washing until pH of 7 and drying at a constant temperature of 40 DEG C at constant humidity of 50%. The film has thickness of 1.5-2 microns, breaking strength greater than or equal to 180MPa, breaking elongation greater than 3.7% and initial modulus greater than 4.5GPa. The film can be used as an anticoagulation material, a bone repair material and wound dressing.

The invention discloses a method for preparing chiral alpha-alkyl substituted glycine hydrochloride. The method comprises steps of: selecting commercialized or easily prepared tert-butyl glycinate as an initial raw material; inducing alpha position chiral alkyl substitution through a chiral adjuvant (S) camphor; carrying out chemical split to obtain alpha-alkyl substituted glycine ester; and finally hydrolyzing to obtain optically pure alpha-alkyl substituted glycine hydrochloride. R represents C1-C12 saturated or unsaturated alkyl, or C1-C12 saturated or unsaturated alkyl substituted phenyl. The method uses cheap and easily available raw materials, has high reaction yield, stable technical condition, simple operation and no pollution; the obtained product has an optical purity greater than 99%; therefore, the invention provides a new idea and method for large-scale production of amino acid with high chiral purity.