The invention relates to a method for preparing lead-bearing radiation-proof organic glass, belonging to the functional high molecular material polymerization technical field. The method synthesizes organic carboxylic acid lead salt through organic synthesis and modification of inorganic lead salt, adds the organic carboxylic acid lead salt into water-in-oil type microemulsion which consists of methyl methacrylate (MMA), a surfactant, an auxiliary surfactant, water and so on, initiates under the condition of a thermal initiator and polymerizes an organic glass sheet. Moreover, the performanceof the organic glass sheet is tested, and the result reveals that the impact strength, the tensile strength, the light transmittance, the refractive index, the glass transition temperature and the radiation-proof property of the organic glass prepared by polymerization of the microemulsion are all superior to those of common organic glass. The invention provides a novel method for synthesizing functional high molecular materials. The method has a simple and convenient technique; the synthesized sheet has superior performance, can make up for the defects of an inorganic radiation-proof glass sheet, and is hopeful to become practical novel radiation-proof materials.