The invention discloses a method for manufacturing multi-core MgB2 superconductive wires through the extrusion technology. The method includes the steps that first, precursor powder is prepared; second, the precursor powder is installed in a pipe to prepare a primary complex, and single-core wires are obtained through drawing machining; third, the precursor powder is installed in a pipe to prepare a secondary complex; fourth, the secondary complex processed through pre-heating seal welding is extruded, and multi-core rods are obtained; fifth, the multi-core rods are stripped and drawn to obtain multi-core wires, the multi-core wires are subjected to heat treatment, and then the multi-core MgB2 superconductive wires are obtained. According to the method, on the basis of a traditional power pipe-installing technology, a large single-pass machining deformation amount is adopted for manufacturing the multi-core MgB2 superconductive wires, in other words, the extrusion technology is adopted for manufacturing the multi-core MgB2 superconductive wires, because the secondary complex is in a very favorable three-dimensional stress state in extrusion, good metallurgical bonding will be achieved between different metal interfaces in the secondary complex along with the large extrusion deformation amount, the manufactured multi-core rods are high in composite strength, and the compactness and the yield strength of the multi-core MgB2 superconductive wires can be significantly improved.