44 results about "M-toluidine" patented technology

The invention discloses a corrosion-resistant oil-water separation mesh membrane as well as a preparation method and application thereof. The corrosion-resistant oil-water separation mesh membrane is a fiber braiding mesh coated with conducting polymer aquogel which is one or a mixture of some of polypyrrole, poly thiophene, polyaniline, polyparaphenylene, poly-m-toluidine,poly (1-methylene-2-methyl naphthalene) -N-pyrrole, poly ethylene dioxy thiophene, poly 3-ethyl thiophene, poly 3-hexyl thiophene and poly 2, 5-dimethoxy aniline; and the fiber braiding mesh is one of a metal fiber braiding mesh, an inorganic fiber braiding mesh and an organic fiber braiding mesh. The corrosion-resistant oil-water separation mesh membrane not only can implement the effective separation of different types of water and oil, but also has the favorable characteristics of salt resistance, strong acid resistance and strong alkaline resistance.

The invention discloses a detection kit for determining the content of creatinine in serum by an enzymic method. The detection kit comprises a reagent R1 and a reagent R2, wherein the reagent R1 contains 3-10g/L of buffering solution with the pH value being 7.5-8.0, 0.2-0.5g/L of EDTA, 0.5-2g/L of N-ethyl-N-(2-hydroxyl-3-sulfopropyl) m-toluidine sodium salt, 1 per mill-5 per mill of a surface active agent, 0.2-1g/L of sarcosine oxidase, 1-5KU/L of ascorbate oxidase, 2-5KU/L of creatinase and 0.5-1g/L of a stabilizing agent; the reagent R2 contains 3-10g/L of buffering solution with the pH value being 7.5-8.0, 0.1-0.5g/L of 4-aminoantipyrine, 0.1-0.4g/L of potassium ferricyanide, 2-8g/L of creatininase amidohydrolase, 1-6KU/L of peroxidase and 0.5-2g/L of a preservative. The detection kit disclosed by the invention is excellent in stability, strong in interference resistance and high in clinical application value.

The invention relates to 100# lead-free aviation gasoline and a preparation method thereof. The 100# lead-free aviation gasoline comprises, by volume, 10-18% of industrial isopentane, 1-11% of light alkylated oil, 45-55% of industrial isooctane, 15-22% of toluene, 0-4% of m-xylene, 5-11% of cumene, 1.5-5.5% of aniline, 0.5-3.5% of N-methyl aniline and 0-3% of m-toluidine. The components are blended to form the finished product. Compared with the prior art, the 100# lead-free aviation gasoline does not contain lead and solves the problem of lead pollution of aviation gasoline. Through the optimized combination of the components, the 100# lead-free aviation gasoline quality is high and the 100# lead-free aviation gasoline satisfies the quality index requirements. The 100# lead-free aviation gasoline has a high economic value. The 100# lead-free aviation gasoline blending process is simple and is conducive to industrial production.

The invention discloses a method for preparing high-purity torasemide and a crystal form I thereof. The method comprises the following steps of: reacting 4-chloro-3-pyridine sulfonamide and m-toluidine serving as raw materials to obtain 3-sulfamoyl-4-(3-methyl phenyl) aminopyridine, refining, and reacting with 1,1'-carbonyldimidazole and isopropamide, directly introducing isopropyl carbamyl, thus obtaining the high-purity torasemide, wherein the purity (high performance liquid chromatography (HPLC)) of the torasemide is more than 99.5 percent. The prepared torasemide has proper granularity, seed crystal is not required for crystal transformation, the torasemide can be directly transformed into the variant crystal form I, and a chemically pure torasemide variant I is obtained. The preparation method is strong in process controllability, easy and convenient to operate and high in reproducibility, and facilitates industrialized production.

An environment-friendly type lubricating oil additive is composed of the following raw materials in parts by weight: 7 to 12 parts of castor oil polyoxyethylene ether, 3 to 6 parts of molybdenum disulfide colloid, 2 to 7 parts of n-octadecanoic acid, 4 to 8 parts of critic acid, 6 to 13 parts of molybdenum dialkyldithiophosphate, 4 to 8 parts of butyl oleate, 3 to 6 parts of tackifier, 5 to 8 parts of o-toluidine/m-toluidine, 6 to 8 parts of methyl citrate, 4 to 7 parts of triphenyl phosphorothionate, 6 to 12 parts of sulfurized isobutylene, 5 to 8 parts of benzotriazole amine, 2 to 6 parts of n-butyl acetate, 1 to 4 parts of p-methoxyl styrene, 8 to 16 parts of linoleic acid, 4 to 6 parts of methanol, 7 to 13 parts of polyethylene glycol monomethyl ether, 4 to 7 parts of magnesium silicate, and 4 to 6 parts of fluorine surfactant. The provided environment-friendly type lubricating oil additive can improve the wear-resistant performance, extreme pressure resistant performance, and oxidation resistant performance of lubricating oil, has the advantages of convenient operation and environment-friendliness, and is according with the green and environment-protection requirements.

The invention discloses a trisazo carmoisine, and also discloses a preparation method thereof. The preparation method comprises the following steps: diaminoazobenzene, hydrochloric acid and a sodium nitrite solution react in water, and residual nitrous acid is eliminated after the reaction to obtain a diazonium salt solution; and reaction raw materials react with the diazonium salt solution to finally obtain the corresponding trisazo carmoisine, wherein the reaction raw materials are N-ethyl-N-benzyl aniline-3'-sulfonic acid and N-ethyl-N-benzyl m-toluene-3'-sulfonic acid. The trisazo carmoisine disclosed by the invention does not contain carcinogenic dye or heavy metal dye, and belongs to safe and environment-friendly dye. The dye composition has good water solubility, is gentle in dyeingin a dyeing system and good in leveling property, can be efficiently combined with protein and polyamide fibers, is high in dyeing rate, enables dyed fibers to have excellent color fastness, and is an ideal substitute for metal complex dyes.

The invention discloses a process for preparing m-cresol by a nitrogen oxide gas, which comprises the following steps: infusing the nitrogen oxide gas in m-toluidine sulfate for carrying out diazotization, hydrolyzing in the presence of an organic solvent and under an acidic condition, carrying out flash evaporation on the acid phase under the condition of negative pressure, returning the acid phase to a salifying step, dehydrogenating and rectifying the organic phase to obtain m-cresol products. The invention uses the nitrogen oxide gas as a diazotizing agent and inorganic salts do not existin a waste acid so that the waste acid is possibly used industrially. The hydrolysis is carried out in the presence of the organic solvent, the m-toluidine generated by the hydrolysis is quickly dissolved in the organic phase, the side product tarry matters generated in the reaction is few, the yield of the m-toluidine is improved, the salt-free waste acid is subjected to the flash evaporation under the negative pressure at a certain temperature, organic matters are stripped while the reaction water is removed, sulfuric acid is used, the dosage of the sulfuric acid is reduced, the purity of the m-toluidine products prepared by the process of the invention is 99.7% and the yield is more than 90%.

The invention discloses a method for producing hydrochloride of a dopamine D4 receptor agonist A-412997. The method comprises the following steps of: obtaining lithium pyridine by using a cheap reagent of butyl lithium as an exchange reagent; reacting with N-Boc-4-piperidone to obtain a compound of 1-N-Boc-4-(2-pyridyl)-4-hydroxypiperidine; removing water molecules, adding Boc, hydrogenating, removing the Boc and performing other steps to obtain a compound of 4-(2-pyridyl)piperidine dihydrochloride; and performing substitution on the 4-(2-pyridyl)piperidine dihydrochloride and a compound of chloracetyl m-toluidine to obtain the target product, namely the hydrochloride of the dopamine D4 receptor agonist A-412997. The process flow is simple, the method is suitable for industrial production, the reagent has low price, the yield is high, the total yield is 44.5 percent, and the method is an effective method for producing the hydrochloride of A-412997.

The invention discloses a catalyst for m-toluidine prepared from m-nitrotoluene through gas phase hydrogenation, a preparation method and a regeneration method thereof. In the catalyst, SiO2 is used as a carrier and copper is used as a main active ingredient; and based on the weight of the catalyst, Cu accounts for 10 to 30 percent and the balance is SiO2. The method for preparing the catalyst comprises the following steps: weighing copper nitrate and silica gel; adding distilled water into the copper nitrate until the copper nitrate is fully dissolved; adding solution of ammonia water into the mixture until no precipitate is generated in the solution; adjusting the pH value; adding the silica gel into the prepared solution and stirring the solution; filtering and washing the obtained solution until the filtrate becomes colorless; and finally drying and baking the filtrate to obtain the catalyst. The catalyst after being inactivated can be regenerated through an air oxidizing roasting method. The catalyst has the advantages of long service life, excellent catalytic activity, high selectivity, simple preparation and regeneration methods and low cost, and wide application.

A process for continuously preparing meta-tolylphenol includes such steps as continuously adding the diazonium salt of meta-tolylamine to diluted sulfuric acid, and reacting at 106-150 deg.C while controlling the concentration of sulfuric acid to 25-64 wt.%. Its advantages are low cost, high output rate, small reactor volume, and cyclic use of sulfuric acid after treated by macroreticular resin.

The invention relates to the technical field of chemical industry and discloses a method for detecting impurities, namely meta-methylnitrobenzene and m-toluidine, in m-cresol simultaneously. The method comprises the following steps: diluting a to-be-detected m-cresol sample by using a mixed solvent of dimethyl sulfoxide, methanol and DMF to obtain a test sample solution, and taking the mixed solution of the meta-methylnitrobenzene and the m-toluidine as a control product solution; and performing sample introduction on the test sample solution and the control production solution by a headspace mode, performing gas chromatographic detection, and calculating the content of the impurities, namely the meta-methylnitrobenzene and the m-toluidine, in the m-cresol according to an external standard method and based on peak area. The sample is diluted by the mixed solvent of the dimethyl sulfoxide, the methanol and the DMF, sample instruction is conducted by the headspace mode, and chromatographic detection is conducted, so that the content of the minute amount of meta-methylnitrobenzene and m-toluidine in the product can be detected simultaneously and accurately, the detection sensitivity is greatly improved, and important practical value on production control of the product and quality control of the product is achieved.

The invention discloses a clutch pump piston and a preparation method thereof. The preparation method comprises the steps of 1) smashing sweet potato, putting the smashed sweet potato into a yeast solution for fermentation, then filtering and taking a filter cake, so as to obtain a modifier; 2) calcining bentonite and iron-ore slag, then putting the calcined bentonite and iron-ore slag in X-rays for activating treatment, so as to obtain an activator; 3) mixing makrolon, an ethylene-vinyl acetate copolymer, cellulose propionate, vinyl propionate, n-butyl alcohol, nanometer magnesia, a rare-earth oxide, a potassium titanate whisker, m-toluidine, anilmomethyl triethoxy silane, pyrimidine, p-benzoquinone, simethicone and the modifier with the activator, cooling, molding and pelleting to obtain a clutch pump piston material; 4) melting the clutch pump pulling bar material at 195 to 205 DEG C, and then the clutch pump piston is obtained by extrusion molding. The clutch pump piston prepared by the method has excellent mechanical property.

The invention discloses a preparation method of high-strength polyimide, which comprises the following steps: (1) preparing an organic solvent, and mixing transparent fibers in the organic solvent in a dispersed manner; (2) adding pyromellitic dianhydride and m-toluidine into an organic solvent, and polymerizing the pyromellitic dianhydride and the m-toluidine; (3) adding the biphenyl tetracarboxylic dianhydride, the oxydiphthalic anhydride or the benzophenone tetracarboxylic dianhydride into the organic solvent, and polymerizing the biphenyl tetracarboxylic dianhydride, the oxydiphthalic anhydride or the benzophenone tetracarboxylic dianhydride and the m-toluidine; and (4) carrying out imidization on the polyimide acid generated in the organic solvent. The invention also provides high-strength polyimide and production equipment. According to the present invention, the dispersed transparent fiber yarn is added in the organic solvent in advance, the transparent fiber yarn and the polyimide are subjected to composite molding after the polyimide is subjected to tape casting, and the transparent fiber yarn has the high strength, such that the prepared polyimide has the good strength;

The invention relates to an environmentally friendly preparation method of a solvent blue 63 dye. The preparation method comprises (a) adding m-toluidine into a reaction container, orderly adding 1-methylamino-4-bromoanthraquinone, an alkali metal hydroxide and a copper salt into the reaction container along with stirring, heating the mixture to 100 to 130 DEG C and carrying out a reaction process for 4 to 7 hours until a terminal point, wherein a mass ratio of 1-methylamino-4-bromoanthraquinone, m-toluidine, alkali metal hydroxide to copper salt is 6: 12-16: 3-4: 0.04-0.08, and (b) cooling the product obtained by the step a to 60-70 DEG C, then adding methanol into the product, carrying out separation, carrying out stirring, carrying out cooling to 30-50 DEG C, and carrying out filtration, washing and drying. The method has the advantages of high reaction purity, few side reactions, short reaction time, obvious crystallization, washing easiness and less washing wastewater.

The invention discloses a preparing method for a sea sedge baked piece capable of reducing blood pressure. The method includes the following step: pulping, first baking, seasoning, second baking and slicing and package. The slurry comprises, by weight: 15-25 parts of carrot slurry, 1.5-5.5 parts of leavening agent liquid, 1.0-3.0 parts of thickening agent liquid, 100-120 parts of laver slurry, 0.2-0.4 part of alloisoleucine and 0.01-0.03 part of N,N-bis-n-propyl-m-toluidine. The beneficial effects are that the sea sedge baked piece prepared by the method has good piece-forming ability and film-forming ability, has high the sense organ fraction, is rich in gamma-aminobutyric acid (GABA), and has excellent effects of reducing blood pressure and protecting cardiac muscle. Especially the alloisoleucine and N,N-bis-n-propyl-m-toluidine are added into the laver slurry, the combination force between the active constituent and ACE activity structural domain of the laver is enhanced, the substrate competitiveness is improved, so that the effect of reducing blood pressure of the sea sedge baked piece is improved.

The invention discloses a method for preparing CLT acid by taking m-toluidine as a raw material, and belongs to the field of chemical synthesis. The method solves the problems that existing CLT acid production is low in yield, not environmentally friendly and the like. The method comprises: S01) an acylation step, namely a step of reacting m-toluidine and acetic anhydride to obtain acylation reaction solution; S02) a chlorination step, namely a step of adding acetic acid and concentrated hydrochloric acid into the acylation reaction solution, then adding hydrogen peroxide, and finally adding an aqueous solution containing sodium sulfite to obtain a chlorination reaction solution; S03) a hydrolyzing step to form salt, namely a step of adding concentrated sulfuric acid into the chlorinationreaction solution, and removing the solvent after reaction; S04) a transposition sulfonation step, namely a step of adding chlorobenzene into the solvent-removed reaction solution obtained in the stepS03, heating the mixture, adding dichlorobenzene, heating the mixture again, reacting the mixture for 7-10 hours with the temperature of the system being maintained at a temperature higher than 170 DEG C, and stopping heating; and S05) a step of post-treatment to obtain a finished product that is the CLT acid. The method has the advantages of environmental protection and the like.

The invention relates to a preparation method of 3-methyl-4-isopropylaniline. The preparation method includes the following steps: (1) dissolving m-toluidine in sulfuric acid solution 50-98% in mass concentration as a component 1, then adding an isopropylation reagent into another container to serve as a component 2, simultaneously feeding the component 1 and the component 2 into a jet mixer with the flow rate of 5-10:1 to be mixed at the temperature of 10-35 DEG C, and then reacting at the temperature of 60-95 DEG C through a quartz reaction tube to obtain reaction solution for alkylation reaction; (2) subjecting the reaction solution obtained in the step (1) to separation and purification to obtain 3-methyl-4-isopropylaniline. The 3-methyl-4-isopropylaniline prepared through the method has the advantages of mild reaction condition, high yield, few by-products, less pollution and the like, and the problems of a lot of by-products, strict conditions and severe pollution in the preparation process of the 3-methyl-4-isopropylaniline in the prior art are solved effectively.