46 results about "SODIUM THIOGLYCOLATE" patented technology

A camptothecin-containing pharmaceutical composition which contains: (a) camptothecin or a derivative thereof, and (b) one or more compounds selected from among ascorbic acid or a salt thereof, sodium hydrogen sulfite, sodium sulfite, potassium pyrosulfite, sodium erythorbate, sodium thioglycolate, sodium pyrosulfite, and α-thioglycerin. The pharmaceutical composition is useful in that, after storage for a long period of time or under light-irradiation conditions, camptothecin or a derivative thereof contained therein undergoes minimum degradation.

The invention discloses a preparation method of mercaptoacetic acid, which comprises the following steps: 1) In a reactor, add monochloroacetic acid, sodium monochloroacetate and carbon disulfide, stir, add alkali solution dropwise, after the reaction is completed, separate the oil phase and the water phase ;2) After separation of the oil phase mixture, unreacted carbon disulfide is recovered and recycled, and the residual mixture is acidified into a weak acid solution, which is extracted by adding an organic solvent for 2 to 3 times, the organic phase is combined, washed with saline solution and water, and the oil phase is separated and the water phase; 3) The separated oil phase is distilled to recover the organic solvent, and the residue is thioglycolic acid. Carbon disulfide reacts with alkali to generate mercapto groups, and then reacts with sodium monochloroacetate to generate sodium thioglycolate. Adding an appropriate amount of acid, organic solvent, and alkali solution, the cost of raw materials is low and the consumption of reagents is low; excessive carbon disulfide is recovered and recycled for use. High efficiency, clean production process; mild reaction conditions, short reaction time, no need for high temperature and high pressure, low equipment investment costs.

The invention discloses a culture medium and a detection method for gas-producing bacteria in cooking wine, comprising the steps of: diluting a sample of cooking wine to be tested, then inoculating it into a fermentation tube containing the culture medium, and cultivating it at 30°C±1°C for 48±2h Finally, detect the gas-producing bacteria according to the gas production of the fermentation tube; the culture medium is composed of the following raw materials in parts by weight: 10-30 parts of sucrose, 3-6 parts of yeast extract, 4-10 parts of peptone, and 3-3 parts of sodium chloride 10 parts, 2 to 8 parts of rice wine, 1 to 2 parts of Tween-80, 0.05 to 1 part of sodium thioglycolate, 0.2 to 0.6 parts of magnesium sulfate heptahydrate, 0.01 to 0.1 parts of methionine, and 0.01 to 0.01 parts of cysteine 0.2 parts, 1000 parts of distilled water. Using the detection method of the present invention, it is possible to detect cooking wine spoilage bacteria that are difficult to grow on conventional medium, and the detection results of the detection method have a good correlation with food deterioration and gas production. The quality provides a basis; the method has the advantages of high detection efficiency, simplicity, low cost, and easy promotion, and is suitable for industrial application in production.

The invention provides a production method of high-grade sodium thioglycollate powder. The production method comprises the following steps of firstly, uniformly mixing chloroacetic acid and deionized water according to the mass ratio to obtain a chloroacetic acid solution, then adding sodium carbonate into the chloroacetic acid solution, and uniformly mixing to obtain a sodium chloroacetate solution; secondly, adding sodium thiosulfate into the sodium chloroacetate solution, uniformly mixing and then carrying out temperature-rise condensation to obtain a condensation compound; thirdly, adding sodium hydroxide into the condensation compound, uniformly mixing and then carrying out temperature-reduced mercaptoethylation to obtain a mercaptoethylation product; fourthly, carrying out vacuum drying treatment on the mercaptoethylation product to obtain the high-grade sodium thioglycollate powder. According to the production method provided by the invention, the problems about low grade of products, high transportation expenses, high packing expenses, easiness in oxidation and the like existing the prior art are solved; sodium thioglycollate produced by the production method provided by the invention is in a powder shape and does not generate three wastes; the grade of the product is over 35 percent; the high-grade sodium thioglycollate powder belongs to a green environment-friendly product.