The invention relates to the technical field of
medicine, in particular to a brazilin-containing pharmaceutical composition and a preparation method and application thereof, and preparation raw materials comprise brazilin and a
zinc preparation. Through the synergistic effect of the brazilin and the
zinc preparation, the
fibrosis area after
myocardial infarction can be remarkably reduced, the cardiac function after
myocardial infarction can be improved, and the
cardiac fibrosis degree can be effectively relieved by inhibiting the expression of
fibrosis-related genes and proteins at transcription and
protein levels.