The invention discloses a high-yield cultivation method of pollution-free grapes. The method mainly includes: planting ditch treating, seedling collecting and treating, cutting, building racks, shaping, water and fertilizer managing, cluster managing and the like. The method has the advantages that rare earth and biological organic fertilizer is creatively used to supply fertilizer for grape growth, the features that the rare earth can promote fertilizer nutrition absorption of crops, promote photosynthesis of crops, improve fruit quality, enhance drought resistance, cold resistance and disease and pest resistance of crops, promote crop root growth, biomass, quality and stress resistance, and the like are fully utilized in combination with the features that the organic fertilizer is convenient to manufacture, low in cost, capable of improving soil quality, free of pollution, and the like, zero chemical fertilizers and pesticides during the whole grape cultivating process are achieved, and pesticide residue is avoided; by comprehensive scientific management of the whole process, fruit setting rate is increased greatly, fruit size increasing is achieved, fruit crack is reduced, fruit quality is increased, and good social and economical benefits are achieved.