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44results about How to "Broad-spectrum bactericidal activity" patented technology

Fatty acid composition

The invention relates to a fatty acid composition, which is diluted at normal temperature and in cold water to form solution used for cleaning of sterilization, fungicide and antivirus. The fatty acid composition comprises at least the following components: component A: food fatty acid comprising at least octyl decanoic acid and nonanoic acid; component B: surfactant comprising alkane sulfonate; component C: acid. The fatty acid composition has the advantages that the fatty acid composition or the diluted solution thereof has good stability, bactericidal and antiviral activity under the water temperature of 4-20 DEG C, no phase separation or crystallization, thus having safer use performance, and active components are low in cost, having more broad-spectrum bactericidal activity which can kill various bacteria, epiphytes and viruses. The fatty acid composition or the diluted solution thereof can be used for sterilization, fungicide and antivirus, which has high-efficient and quick killing effect; the sterilizing rate can reach more than 99.999 percent with contact time less than 1 minute; The fatty acid composition or the diluted solution thereof also has strong cleaning ability, and can keep effective even in hard water; the killing ratio for poliovirus reaches 99.9999 percent and the poliovirus can be killed immediately.
Owner:SICHUAN LOMON BIO TECH CO LTD +1

Disinfectant prepared from plant extracts as well as preparation method for disinfectant

The invention relates to a disinfectant prepared from plant extracts. The disinfectant prepared from the plant extracts comprises the following raw materials in percentage by weight: 0.05 to 0.5 percent of chlorogenic acid, 0.1 to 1 percent of gallic acid, 0 to 1 percent of sophocarpidine, 0 to 0.8 percent of clove oil, 0 to 1 percent of peppermint oil, 0 to 1 percent of moxa volatile oil or spearmint oil, 0.1 to 2 percent of tween 80, 5 to 50 percent of ethanol, 0.1 to 1 percent of sodium citrate, 0 to 0.8 percent of lauryl sodium sulfate, 0 to 0.5 percent of fragrance regulator and the balance of pure water. The invention also provides a preparation method for the disinfectant. The disinfectant prepared from the plant extracts and the preparation method for the disinfectant have the beneficial effects that: the disinfectant belongs to a pure Chinese medicine compound disinfectant preparation, is safe for human and livestock to use, does not have corrosivity and toxic or side effect, is insusceptible to medicine resistance after a long-time use, has good disinfection effect, avoids environmental pollution, has wide application, can be used for disinfecting air and can also be used for disinfecting the surfaces of skin, clothes, tableware, furniture and the like, and meets universal requirements of people.
Owner:WODE GUOTAI BEIJING TECH DEV

Tegillarca granosa galactose lectin Tg-GAL and application thereof

The invention aims at providing galactose lectin Tg-GAL and application thereof. An amino acid sequence of the galactose lectin Tg-GAL is as shown in SEQ ID NO:1. The tegillarca granosa galactose lectin (Tg-GAL) fusion protein expressed in the invention has broad-spectrum bactericidal capability, and especially has a stronger sterilizing effect for aquatic animal pathogenic bacterium vibrio, so that a foundation is laid for developing a novel medicament with microorganism-resistant activity and a novel disease prevention and control treatment preparation for substituting antibiotics on aquaculture industry. Compared with a method for extracting galactose lectin from a natural resource, the preparation method disclosed by the invention ensures that galactose lectin is on a large scale and is free of toxicity, so that low-cost large-scale production is possible, and therefore, a novel way is provided for developing sea-farming cowry feed additives and bacterial disease vaccines.
Owner:ZHEJIANG WANLI UNIV

Application of alpha-mangostin in controlling plant diseases

The invention discloses an application of alpha-mangostin in controlling plant diseases. Tests prove that alpha-mangostin has agricultural fungicidal activity. The compound has very strong fungistatic action on mango anthracnose pathogens, diplodina sp., botrytis cinerea, and exserohilum turcicum when the testing concentration is 100 mg / L, and has an EC50 value of 18 mg / L-35 mg / L; the compound has certain spore germination inhibition effect on exserohilum turcicum and botrytis cinerea, and the EC50 values are 66.20 mg / L and 50.43 mg / L respectively; meanwhile, in-vivo test results show that the compound has very good protection and treatment effects on rubber tree powdery mildew when the testing concentration is 500 mg / L, and the protection and treatment effects on rubber tree powdery mildew are 75.61% and 70.12% respectively, which are higher than those of a control drug of prochloraz. The above results indicate that alpha-mangostin has broad-spectrum fungistatic action on plant pathogenic fungi, which lays the foundation for the development of novel pollution-free plant-derived pesticides by further using mangosteen shells.
Owner:ENVIRONMENT & PLANT PROTECTION INST CHINESE ACADEMY OF TROPICAL AGRI SCI

N'-substituted benzal-1,2,3,4-tetrahydroquinoline base-1-(sulfo)hydrazide compound and preparation method and application thereof

The invention belongs to the technical field of pathogenic bacterium control, and particularly relates to an N'-substituted benzal-1,2,3,4-tetrahydroquinoline base-1-(sulfo)hydrazide compound and a preparation method and application thereof. By substituting 1,2,3,4-tetrahydroquinoline fragments excellent in biological activity into a substituted benzaldehyde thiosemicarbazone compound, the N'-substituted benzal-1,2,3,4-tetrahydroquinoline base-1-(sulfo)hydrazide compound novel in structure is obtained. The structure of the compound is seen in the formula I (please see the formula in the specification). The preparation method is easy to operate and free of harmful by-products, and raw materials are easy to obtain. The compound has broad-spectrum bactericidal activity, particularly has an obvious restraining effect on Valsa mali, rhizoctonia solani and gaeumannomyces gramini, and can be used as a bactericide for preventing and curing plant diseases.
Owner:CHINA AGRI UNIV

Fatty acid complex

The invention discloses a fatty acid complex. The fatty acid complex comprises the following components in parts by weight: 2.2-3 parts of mixed fatty acid, 16-40 parts of a surfactant and 40-60 partsof auxiliary acid, wherein the mixed fatty acid is a mixture of octanoic acid, nonoic acid and capric acid; the auxiliary acid is lauric acid or a mixture of the lauric acid and citric acid. The fatty acid complex has broad-spectrum bactericidal and antiviral activity, can kill polioviruses, foot-and-mouth disease viruses, porcine reproductive and respiratory syndrome viruses and avian influenzaviruses, has the staphylococcus aureus and escherichia coli killing rate as high as 99.99999%; the fatty acid complex has excellent storage stability under a diluted condition, is applied to a food disinfectant, has an excellent food preserving function, is free of cleaning during disinfection, free of metal corrosion, practically non-toxic and non-irritant to skin, and is unlikely to volatilize;the fatty acid complex has acidic pH and a light coconut scent, disinfecting cleaning sewage does not pollute the environment, and the fatty acid complex can be reused in some disinfecting scenes.
Owner:上海康归生物科技有限公司

Ferment leaf fertilizer for green vegetables and preparation method of ferment leaf fertilizer

The invention specifically discloses ferment leaf fertilizer for green vegetables. The ferment leaf fertilizer can improve the absorption rate of a leaf surface for nutrients, promotes photosynthesis, enables the leaf to grow vigorously, and has an antibacterial insect repelling efficacy. The ferment leaf fertilizer is prepared by mixing a solution A and a solution B according to a weight ratio of 1: (1.0 to 1.3), the pH value of the mixed solution is adjusted to 6.0 to 6.5 by adding acid, wherein the solution A is prepared by fermenting the following components for 3 to 5 months at a temperature of 25 to 35 DEG C and removing the ferment residues: brown sugar, sodium chloride, silkworm excrement, tea seed cake, fresh fruits and vegetable residues, water, activated EM flora and bacillus aceticus; and the solution B is prepared by adding water to the following components to 100 parts: biochemical fulvic acid type B, sugar alcohol, urea, boric acid, ammonium sulfate, zinc sulfate, magnesium sulfate, manganese sulfate, ferrous sulfate, ammonium molybdate, potassium dihydrogen phosphate and a penetrating agent.
Owner:福建绿滢生态农林发展有限公司

Chinese violet coumarin with anti-inflammatory and antiseptic activity and preparation method and application thereof

The invention discloses a Chinese violet coumarin with anti-inflammatory and antiseptic activity and a preparation method and application thereof. The preparation method of the Chinese violet coumarin with the anti-inflammatory and antiseptic activity comprises the following steps of (1) drying Chinese violet residues at 45 DEG C and crushing the dried Chinese violet residues into Chinese violet powder; (2) irradiating the Chinese violet powder under ultraviolet rays for 30 min for sterilization; (3) adding water, 3 times as much as the weight of the sterilized Chinese violet powder, into the sterilized Chinese violet powder, and then adding in complex enzymes, uniformly mixing and placing the mixture in a 55 DEG C thermostatic water bath for 1.5 h; (4) adding organic extracting agent into the Chinese violet powder and then performing reflux extraction twice for 35 min each time, and performing decompressed vacuum filtration, concentration and vacuum drying to obtain the Chinese violet coumarin. The prepared Chinese violet coumarin with the anti-inflammatory and antiseptic activity has broad-spectrum bacteriostatic, bactericidal and anti-inflammatory activity.
Owner:GUANGZHOU JUZHU GENERAL TECH INST CO LTD

Tegillarca granosa hemoglobin Tg-HbIIA and application thereof

The invention relates to tegillarca granosa hemoglobin Tg-HbIIA and application thereof. An amino acid sequence is SEQ ID NO: 1, and a nucleotide sequence is SEQ ID NO: 2. The tegillarca granosa hemoglobin Tg-HbIIA is sued for preparing an immunity enhancer. Tegillarca granosa hemoglobin gene HbIIA fusion protein represented by the tegillarca granosa hemoglobin Tg-HbIIA has broad-spectrum bactericidal activity and has strong bactericidal effect, especially on pathogenic bacterium vibrio of aquatic animals so that a foundation is established for development of novel medicine with anti-microbial activity and novel disease preventing and curing preparation for replacing antibiotics. Compared with traditional methods for extracting hemoglobin from natural resources, by means of a preparation method for the tegillarca granosa hemoglobin Tg-HbIIA, a large scale of non-toxic hemoglobin can be prepared, low-cost scale production becomes possible, and a new way is provided for development and preparation of mariculture shellfish feed additives and bacteriosis vaccine.
Owner:ZHEJIANG WANLI UNIV

Azophenylene-1-bishydrazide carboxylate compound and bactericidal composition comprising compound

The invention discloses an azophenylene-1-bishydrazide carboxylate compound. The azophenylene-1-bishydrazide carboxylate compound is characterized by being represented by a general formula (I), wherein the structural formula is as shown in the specification, and R is substituted phenyl containing one or more saturated or unsaturated hydrocarbyl groups, alkoxy, halogens, fluorine-containing methyl, nitro, cyano, ester group, keto and formyl group, substituted pyridyl, substituted furyl, substituted pyrazolyl, substituted thiazolyl and substituted thienyl. The compound disclosed by the invention simultaneously has broad spectrum insecticidal and bacterial activities, and can be used for controlling diseases caused by multiple pathogenic bacteria such as oomycete, basidiomycetes, ascomycetes, imperfect fungi and the like on various crops.
Owner:YANGTZE UNIVERSITY

Lysozyme derived from phases and gene and application of lysozyme

The invention relates to a lysozyme derived from phases and a gene and application of the lysozyme. The amino acid sequence of the lysozyme is shown in SEQ ID NO:1. The gene encoding the lysozyme is derived from the phages WP3 collected from deep sea. The lysozyme is subjected to heterologous expression and purification. As is detected, the optimum temperature of the lysozyme is 40 DEG C, more than 50% of vitality can be maintained within the temperature range of 20-60 DEG C, and the lysozyme has a wide acting temperature range; the optimum pH value is 6.0, more than 50% of vitality can be maintained within the pH range of 4.0-10.0, and the lysozyme has a wide acting pH range. The lysozyme has a broad-spectrum bactericidal activity, and can efficiently kill various Gram-positive bacteria and Gram-negative bacteria, excellent gene resources and enzyme resources are provided for developing lysozyme-type antibacterial products, and the lysozyme has a wide application prospect.
Owner:THIRD INST OF OCEANOGRAPHY MINIST OF NATURAL RESOURCES +1

Application of coumarin compound with inhibitory activity on plant pathogenic fungi

The invention relates to application of a coumarin compound with inhibitory activity on plant pathogenic fungi, which is characterized in that the coumarin compound is 7-methoxycoumarin, and the coumarin compound with the concentration of 10-200mu g / mL is used as a bactericide for preventing and treating crop diseases caused by the plant pathogenic fungi in the crop planting process. The 7-methoxycoumarin is a botanical pesticide, has the advantages of being easy to decompose, good in environmental compatibility, relatively safe to non-target organisms and the like, meets the requirements of modern environmental protection and human health, can be used as a novel bactericide for preventing and treating common diseases of crops, and can also be used as a substitute of chemically synthesizedbactericides.
Owner:LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Pineapple preservative and preparation method thereof

The invention discloses a pineapple preservative and a preparation method thereof and belongs to the technical field of fruit and vegetable fresh keeping. The pineapple preservative is prepared by mainly mixing the raw materials of a plant extract and auxiliary materials according to weight proportion, wherein the plant extract is a mixed water extract including longan leaves, lemon leaves, liquorice, honeysuckle and garlic; the auxiliary materials comprise enestroburin, kresoxim-methyl, potassium sorbate, propolis, starch and sodium carbonate. The pineapple preservative is mainly prepared by extracting natural plant elements and synthesizing according to proportioning, reduces or avoids the addition of chemicals and is safe and reliable; the fresh-keeping time is long, the use is convenient, and meanwhile, certain effects such as scar repair of fruits can be achieved; the raw materials can be conveniently obtained and are low in cost, the preparation technology is simple, an obvious fresh-keeping effect can be taken, and the pineapple preservative has wide popularization and market prospects.
Owner:GUANGXI NANNING SHENGQIAN TECH DEV CO LTD

Phenazine-1-carboxylic acid bisamide compounds and application thereof

ActiveCN107629012ABroad-spectrum bactericidal activityBroad-spectrum herbicidal activityOrganic chemistryFungicidesHalogenKetone
The invention provides phenazine-1-carboxylic acid bishydrazide compounds and an application thereof, and belongs to the technical field of preparation of pesticide compounds; the general formula of the compounds has the following structure defined in the specification, wherein R is saturated C2-C6 straight-chain or branched-chain alkyl, unsaturated C2-C6 alkyl, halogen substituted C2-C6 hydrocarbonyl, C3-C8 cycloalkyl, and substituted phenyl containing one or more saturated or unsaturated hydrocarbonyl, alkoxy, halogen, fluorine-containing methyl, nitryl, cyano group, ester group, ketone group and formyl group, substituted pyridyl, substituted furyl, substituted pyrimidyl, substituted pyrazolyl, substituted thiazolyl, substituted thienyl, substituted imidazolyl or substituted triazolyl. The phenazine-1-dihydrazine carboxylic acid compounds have novel structure, can be used for prevention and treatment of diseases on crops and weeds and have market application prospects.
Owner:上海沪联生物药业(夏邑)股份有限公司

Compound 2-hydroxy-3-fluoro-5-nitro-1-phenyl butanone and preparation method and agricultural biological activity thereof

Disclosed are a compound 2-hydroxy-3-fluoro-5-nitro-1-phenyl butanone and a preparation method and an agricultural biological activity thereof. The preparation method comprises the steps: adding nitric acid, acetic anhydride and methanol in a reactor, after stirring for a period of time, cooling the reaction liquid to 0-20 DEG C, adding 2-hydroxy-3-fluoro-1-phenyl butanone, carrying out a reaction for a period of time, adding water into the reaction mixture, then adding ethyl acetate, extracting for multiple times, and thus obtaining the target compound from an organic phase. The compound has relatively high inhibitory effects on apple rot, Chinese cabbage grey mould, citrus anthrax, cotton fusarium wilt, wheat take-all and other plant pathogenic bacteria.
Owner:QINGDAO AGRI UNIV

Oxime ether (ester) compound as well as preparation method and application thereof

The invention belongs to the technical field of pathogenic bacteria control, and particularly relates to an oxime ether (ester) compound as well as a preparation method and application thereof. According to the invention, a 1, 2, 3, 4-tetrahydroquinoline or indole fragment with excellent biological activity is introduced into an oxime ether (ester) compound to obtain a compound with a novel structure. The structure of the compound is shown as a formula I. The compound has broad-spectrum bactericidal activity, particularly has an obvious inhibition effect on rhizoctonia solani, botrytis cinerea and valsa mali, and can be used as a bactericide for preventing and treating plant diseases.
Owner:NORTHWEST A & F UNIV

Endolytic enzyme and perforin composition for resisting colibacteriophage expression as well as preparation method and application thereof

The invention provides an endolytic enzyme and perforin composition for resisting colibacteriophage expression as well as a preparation method and application thereof, and belongs to the technical field of bioengineering. An amino acid sequence of endolytic enzyme is as shown in SEQ ID NO:1, and an amino acid sequence of perforin is as shown in SEQ ID NO:2. The endolytic enzyme Lys 9 and the perforin Hol 9 expressed by bacteriophage have broad-spectrum bactericidal activity, have a relatively good antibacterial effect on various gram-positive bacteria and gram-negative bacteria, and have an obvious killing effect on escherichia coli; the endolytic enzyme Lys 9 has an N-terminal enzyme activity structural domain and can dissociate beta-1,4-glucosidic bonds; the perforin Hol 9 has a conservative structural domain, can destroy cells and transmits information to control the lysis time of the cells; and the composition can be used for preparing medicines for preventing, inhibiting or treating cell infection, and has popularization and application value in the fields of medical treatment and food safety.
Owner:SOUTHWEST UNIVERSITY

Plectasin mature polypeptide dimer fusion protein and preparation method thereof

The invention relates to a plectasin mature polypeptide dimer fusion protein, genes for coding the protein and an expression vector containing a DNA sequence for coding the protein. The invention also relates to a method for expressing the plectasin mature polypeptide dimer fusion protein in recombinant Pichia pastoris. The method comprises the following steps: using the expression vector containing the DNA sequence for coding the plectasin mature polypeptide dimer fusion protein to convert Pichia pastoris and obtain recombinant Pichia pastoris, and performing fermentation culture to secrete the plectasin mature polypeptide dimer fusion protein. The obtained plectasin mature polypeptide dimer fusion protein has bioactivity and can be widely used in the fields such as medical treatments, foods, feeds and scientific researches.
Owner:THE INST OF BIOTECHNOLOGY OF THE CHINESE ACAD OF AGRI SCI +1

Antibiotic-free milk replacer

The invention discloses an antibiotic-free milk replacer, which is prepared from the following raw materials in parts by weight: 21.8 parts of common corn, 15 parts of extruded corn, 20 parts of broken rice, 5 parts of dehulled soybean meal, 2 parts of dietary fiber, 5 parts of low-protein whey powder, 6 parts of extruded full-fat soybeans, 4 parts of fish meal, 5 parts of potato protein powder, 2 parts of emulsified oil, 0.55 part of organic calcium, 1 part of monocalcium phosphate, 2 parts of glucose, 2.5 parts of white sugar, 0.15 part of choline chloride, 2 parts of dried porcine solubles, 3 parts of plasma and 3 parts of a nucleus material. The invention provides a milk replacer capable of controlling suckling pig diarrhea without an antibiotic. The milk replacer is capable of preventing piglet diarrhea by selecting kinds of easy-to-digest raw materials with low stress and low antigen and a plurality of intestinal health technologies, and the effect is relatively obvious.
Owner:青岛大信饲料有限公司

Rice seed treating agent containing prothioconazole, imazalil and cartap and application thereof

The invention discloses a rice seed treating agent containing prothioconazole, imazalil and cartap and application thereof. The rice seed treating agent comprises effective components including prothioconazole, imazalil and cartap, wherein a mass ratio of prothioconazole with bactericidal activity to imazalil with bactericidal activity to cartap with insecticidal activity is (1-15): (1-15): (1-15). The invention also discloses application of the seed treating agent in prevention and treatment of rice bakanae disease or / and rice seedling rot or / and rice aphelenchoides besseyi disease. The seedtreating agent disclosed by the invention can be used for effectively treating the drug resistance of Fusarium fujikuroi to bactericides such as carbendazim, prochloraz and JS399-19, and meanwhile, the potential drug resistance risk of Fusarium fujikuroi to prothioconazole and imazalil is reduced. After prothioconazole, imazalil and cartap are combined, a brand-new new product is developed; and the obtained rice seed treating agent has remarkable the effect on preventing and treating rice bakanae disease, rice seedling rot and rice aphelenchoides besseyi disease, is obvious in synergistic effect, can reduce the use amount of pesticides, and is environmentally friendly and safe.
Owner:ZHENJIANG AGRI SCI INST JIANGSU HILLY AREAS

Preservative for wood transportation

The invention provides a preservative for wood transportation. The preservative for wood transportation comprises the following raw materials in parts by weight: 35 to 52 parts of ketamine, 26 to 34 parts of ammoniacal copper quats, 16-28 parts of zinc dimethyldithiocarbamate or kresoxim-methyl, 56-63 parts of ammonium carbamate, 43 to 51 parts of 2,4,5,6-tetrachloro-3-benzenedicarbonitrile, 2-5 parts of boron carbide and 2 to 5 parts of iron boride. The preservative activity of the preservative for wood transportation is ensured through the adoption of the ammoniacal copper quats; the capability of resisting damage by worms or vermin is ensured through the adoption of the ammonium carbamate; mildew resistance, and stability of the preservative under the condition of illumination and rainwater is ensured through the adoption of the 2,4,5,6-tetrachloro-3-benzenedicarbonitrile; the oxidation resistance and the stability of the preservative for wood transportation can be improved through the adoption of the boron carbide and the iron boride.
Owner:FUJIAN AGRI & FORESTRY UNIV

Aryl substituted thiosemicarbazone compound and preparation method and application thereof

The invention discloses an aryl-substituted thiosemicarbazone compound and a preparation method and application thereof. The structural formula of the compound is as shown in Formula I. The preparation method comprises the steps of: mixing a compound of the formula II and a compound of the formula III in an organic solvent to carry out a condensation reaction to obtain the compound of the formulaI. A salt of the aryl-substituted thiosemicarbazone compound is obtained by reacting the aryl-substituted thiosemicarbazone compound with an acid. The compound and the salt thereof are used in the preparation of a medicament for controlling phytopathogen which is harmful to agricultural production or controlling the phytopathogen which is harmful to agricultural production. The compound has novelstructure and simple preparation method, and has a broad spectrum of bactericidal activity.
Owner:CHINA AGRI UNIV

Compound 2-hydroxyl-3-fluoro-5-nitro-1-phenylbutanone and its preparation method and agricultural biological activity

InactiveCN104326919BBroad-spectrum bactericidal activityHighly effective bactericidal activityBiocideFungicidesAcetic anhydrideEthyl acetate
A compound 2 种 hydroxyl ‑3‑3‑5‑5‑ nitrate ‑1‑1‑ phenobarne and its preparation methods and agricultural biological activity.Add nitric acid, ethylamine and methanol to the reactor. After stirring for a period of time, cool down the reactor to 0 to 20 ° C, add 2‑ hydroxyl ‑3‑l fluorinel phenobarne, and add water to the reaction mixture for a period of timeThen add acetate to extract multiple times to obtain a target compound from the organic phase.This compound has a high inhibitory effect on apple rot, cabbage gray mold, citrus anthrax, cotton wither, and wheat complication.
Owner:QINGDAO AGRI UNIV

Environment-friendly coating with heat insulation and corrosion prevention functions

The invention provides an environment-friendly coating with heat insulation and corrosion resistance, and relates to the technical field of novel coatings. The environment-friendly coating with the heat insulation and corrosion prevention functions is prepared from the following raw materials in parts by weight: 40 to 48 parts of acrylic resin, 0.6 to 0.8 part of acryloyloxyethyl dimethyl ethyl ammonium bromide, 0.5 to 0.6 part of isothiazolinone, 0.5 to 0.8 part of ultraviolet light absorber, 3 to 5 parts of modified far infrared ceramic powder, 0.4 to 0.8 part of coalescing agent, 0.1 to 0.3 part of dispersing agent, 0.1 to 0.2 part of defoaming agent, 2 to 3 parts of kaolin, 1 to 3 parts of talcum powder and 6 to 9 parts of deionized water. By adding acryloyloxyethyl dimethyl ethyl ammonium bromide and isothiazolinone into the coating, the coating can have the antibacterial characteristic, is not easily influenced by microorganisms and is better in corrosion resistance, by adding the modified far infrared ceramic powder into the coating, the multifunctional heat insulation effect of isolation, reflection and radiation can be achieved, the heat insulation effect is better, and vigorous popularization is worthy.
Owner:贵州中亚高科涂料有限公司

5-Substituent-1,2,4-triazole-thione Schiff base compound and preparation method and application thereof

The invention belongs to the technical field of chemical medicines, and relates to a 5-substituent-1,2,4-triazole-thione Schiff base compound and its preparation method and application. Intermediate (I) or intermediate (II) ) respectively reacted with 3,5-dimethyl-4-hydroxybenzaldehyde in glacial acetic acid under reflux, filtered, and dried to obtain 5-substituent-1,2,4-triazole-thione Schiff base compounds. The present invention introduces the active groupimine group into the triazole ring parent body, and prepares and synthesizes a series of triazole Schiff base compounds with multiple active sites, which have good activity, less dosage, less toxic and side effects, and are safe Environmental protection; at the same time, this type of compound can be used as an antifungal drug for crops, which can affect the synthesis of fungal cell walls, thereby inhibiting the growth and proliferation of fungi, and finally play the role of antibacterial or bactericidal.
Owner:NORTHWEST UNIV

Volatile extract with bactericidal activity in fraxinus hupehensis and bactericidal composition thereof

ActiveCN106818893ABroad-spectrum bactericidal activitySignificant bactericidal inhibitionBiocideFungicidesDistillationSclerotinia
The invention discloses a volatile extract with bactericidal activity in fraxinus hupehensis and a bactericidal composition thereof. The extract is prepared by the following method: after carrying out crushing treatment on roots, stems, leaves, flowers and / or seeds of the fraxinus hupehensis at -5 DEG C to 0 DEG C; adding crushed materials into a simultaneous distillation-extractor (SDE) and carrying out distillation and extraction at a temperature of 50 DEG C to 150 DEG C for 1h-72h; cooling to room temperature and standing and layering; taking an organic phase and dehydrating the organic phase with a drying agent; filtering to remove the drying agent, and removing an extracting solvent in vacuum at a temperature of -100 DEG C to 30 DEG C to obtain the volatile extract with the bactericidal activity in the fraxinus hupehensis, wherein an extracting agent used in a distillation and extraction process is selected from ester, ketone, ether, chloralkane, aromatic hydrocarbon or alkane. The volatile extract disclosed by the invention has wide-spectrum insecticidal and bactericidal activity and can be used for preventing and treating diseases and insect pests including rice sheath blight, wheat head blight, potato early blight, walnut root rot disease, rape sclerotinia rot and the like.
Owner:YANGTZE UNIVERSITY

Application of 3,6-disubstituted imidazo[1, 2-b] pyridazine derivatives in preparation of fungicides

The invention belongs to the technical field of farm chemicals, and specifically relates to application of 3,6-disubstituted imidazo[1, 2-b] pyridazine derivatives in preparation of fungicides. The 3,6-disubstituted imidazo[1, 2-b] pyridazine derivatives are prepared and applied in farm chemical preparation. The inhibition activity of the derivatives on nine common plant pathogenic fungi is testedby adopting a hypha growth rate inhibition method; some of the derivatives show excellent fungistat activity, and are expected to be used for preventing and treating plant diseases caused by pathogenic fungi such as wheat scab, rice blast, cotton blight, tobacco brown spot, cabbage black spot, pumpkin blight, apple ring spot, Curvularia lunata(Walk) Boed and potato dry rot.
Owner:GUIZHOU MEDICAL UNIV

Application of 1,5-diaryl-3-trifluoromethylpyrazoles in the control of agricultural fungal diseases

The invention belongs to the technical field of pesticides, and particularly relates to application of 1,5-diaryl-3-pyrazole compound in prevention and control of agricultural fungal diseases. The general structural formula of the 1,5-diaryl-3-pyrazole compound is as shown in the description, wherein R1 is selected from fluorine, methoxyl or methyl; and R2 is selected from -CHOOH, -SO2NH2, -NO2, -F,-C1 or -Br. Compared with a traditional agricultural fungicide, the 1,5-diaryl-3-pyrazole compound provided by the invention is unique in structure, adopts an action mechanism different from that ofa traditional fungicide, and has no cross resistance risks on resistance strains generated by an existing fungicide.
Owner:INST OF PLANT PROTECTION HENAN ACAD OF AGRI SCI
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