The invention relates to a fish feed, and especially relates to a siganus oramin fry mixed feed. The invention further relates to a preparation method of the siganus oramin fry mixed feed. The mixed feed comprises the following components in parts by weight: 18 to 27 parts of squid powder, 7 to 15 parts of bean cake, 6 to 13 parts of bone meal, 5 to 12 parts of locust tree leaf powder, 3 to 8 parts of ajuga ciliate, 2 to 7 parts of sophora flavescens, 2 to 6 parts of ginger, 3 to 7 parts of purslane, 2 to 5 parts of tsaoko fruit, 2 to 6 parts of ligusticum wallichii, 1 to 4 parts of licorice, 1 to 5 parts of peanut vine, 2 to 6 parts of fish oil, 1 to 4 parts of honey, 1 to 4 parts of olive oil, and 1 to 4 parts of composite vitamins. The provided siganus oramin fry mixed feed is developed on the basis of energy metabolism mode and nutritional requirements of siganus oramin fry, can completely replace the fish meal, and has the advantages of high living rate of siganus oramin fry, low feed coefficient, and high specific growth rate.