Patents
Literature
Patsnap Copilot is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Patsnap Copilot

43results about How to "Has a promoting effect" patented technology

Preparation method and application of pelodiscus sinensis collagen peptide

The invention relates to a preparation method of pelodiscus sinensis collagen peptide. The preparation method is characterized by comprising the following steps: (1) preprocessing; (2) enzymatic hydrolysis: adding papain to a collagen solution obtained from the step (1) for enzymatic hydrolysis so as to convert collagen into collagen peptide; (3) enzyme inactivation; (4) centrifugation: centrifuging enzymatic hydrolysate obtained from the step (3) and reserving supernatant liquid; (5) membrane separation: intercepting a collagen peptide component which is less than 10000Da in molecular weight from the supernatant liquid through membrane separation; (6) concentration; and (7) freeze-drying. Meanwhile, the invention also provides application of the collagen peptide in the preparation of drugs, health care products as well as skin care and beauty products having an immune enhancing function. Compared with the prior art, the preparation method disclosed by the invention has the advantages that the pelodiscus sinensis collagen peptide is extracted within 2-4h only by combining a one-time enzymic method and membrane separation technology, so that enzymatic hydrolysis time is effectively reduced compared with general researches which require 5-6; and in addition, the collagen peptide which is less than 10000Da is obtained through separation, so that peptide content and purity of a finished collagen peptide product are significantly improved.
Owner:ZHEJIANG WANLI UNIV

Scorpion venom heat-resistant synthetic peptide and application thereof

The invention belongs to the field of research and development of polypeptide medicines and discloses a scorpion venom heat-resistant synthetic peptide and application thereof. An amino acid sequence of an SVHRP (scorpion venom heat-resistant peptide) is detected out from BmK (Buthus martensii Karsch) which is a traditional Chinese medicine; according to animal experiment verification, a scorpion venom heat-resistant peptide extract liquid sample has pharmacological activity in prevention and treatment of intractable epilepsy, Parkinson's disease and Alzheimer's disease, the sample is subjected to LaGm composite and repeated fast magnetic separation prior to nanoLC-ESI-MS (nano-liter reversed-phase chromatography and electrospray ionization mass spectrometry) integrated mass spectrometry parallel experiment to detect out a polypeptide sequence formed by 15 amino acid residues. The scorpion venom heat-resistant synthetic peptide is prepared by solid-phase chemical synthesis, chromatography purification and mass spectrometry identification. An amino acid sequence of the scorpion venom heat-resistant synthetic peptide is as shown in SEQ ID NO.1 and keeps pharmacological activity and safety of the scorpion venom heat-resistant peptide, and the scorpion venom heat-resistant peptide also has a characteristic of biological activity in promotion of reverse differentiation of neuroglial cells into neural stem cells.
Owner:上海万锦医药科技有限公司

Method for smelting scrap steel through blast furnace oxygen-enriched large-proportion bituminous coal injection

The invention discloses a method for smelting waste steel by blast furnace oxygen-enriched large-proportion bituminous coal injection, which comprises the following steps: charging: all charging materials of a blast furnace comprise sintered ore, pellet ore, lump ore, coke and waste steel, adding the waste steel at the edge ring belt of the blast furnace according to the mass ratio of the waste steel consumption to the ore batch weight in each batch of charging materials of (3-5): 22, and charging into the furnace for smelting; material distribution: the ore-coke ratio at the edge of a furnace wall is 4: 3 or 3: 2, and the mass percent of the central coke adding amount is 29.4-33.3% of that of a coke batch; blowing: blowing coal is mixed coal of anthracite and bituminous coal, and the mass percentage of the bituminous coal is 42-45%; air blowing: the adopted air blowing oxygen enrichment rate is 8-12%, and the standard air speed (standard air volume/air inlet area) is 252-272 m/s; by improving the blast oxygen enrichment rate of the blast furnace, using high-volatile bituminous coal for injection in a large proportion, adding waste steel into the furnace, adjusting the material distribution system, strengthening the central gas flow of the blast furnace and inhibiting the edge gas flow, the stable furnace condition, low consumption and high yield of the blast furnace are realized.
Owner:武汉钢铁有限公司

Method for cooperative treatment of coking desulfurizing waste liquid, calcium-based solid waste and pollutants in industrial smoke

The invention relates to a method for cooperative treatment of coking desulfurizing waste liquid, calcium-based solid waste and pollutants in industrial smoke. The method comprises the following steps: absorbing the oxidized industrial smoke by using absorbent slurry while controlling the pH of the slurry to 6 or higher during the absorption, wherein the absorbent slurry is a mixture of the calcium-based solid waste and the coking desulfurizing waste liquid; after the absorption, discharging the purified smoke, and performing solid-liquid separation on the absorbent slurry; performing impurityremoval and pH regulation on the obtained liquid phase, and heating for decomposition; performing solid-liquid separation to obtain an ammonium thiocyanate product. The method provided by the invention can realize efficient removal of sulfur dioxide, nitrogen oxide and mercury in smoke while recycling an ammonium thiocyanate product with high added value. The method provided by the invention canbe used for performing cooperative treatment on the waste gas, wastewater and waste residue generated in an industrial production process, has the advantages of simple process, low raw material cost and no wastewater discharge in the whole process, realizes cyclic economy of dealing with waste by waste, is suitable for industrial application and creates good economic benefits.
Owner:INST OF PROCESS ENG CHINESE ACAD OF SCI

Application of atractylodes macrocephala polysaccharide and pachymaran as feed additive for improving weaning stress of piglets

The invention discloses an application of atractylodes macrocephala polysaccharide and pachymaran as a feed additive for improving weaning stress of piglets, which belongs to the field of the feed additive. The application of atractylodes macrocephala polysaccharide and pachymaran as feed additive for improving weaning stress of the piglets is characterized in that the appropriate addition amountaccounts for 0.02%-0.08% of mass of a basic feed, the overhigh addition amount affect the growth performance, immunity and feed-to-weight ratio of the piglets, and the excessive low addition amount cannot achieve the effect; the atractylodes macrocephala polysaccharide and pachymaran is composed of atractylodes macrocephala polysaccharide and pachymaran according to a mass ratio of 1-2:1-2, and the content of polysaccharides in atractylodes macrocephala polysaccharide and pachymaran is 37.5%; and the application of atractylodes macrocephala polysaccharide and pachymaran as the feed additive for improving weaning stress of the piglets can effectively alleviate the early weaned stress of the piglets, improves the growth performance of the weaned piglets, and is a very good antibiotic substitute.
Owner:JIANGXI AGRICULTURAL UNIVERSITY

Application of atractylodes macrocephala polysaccharide and pachymaran as feed additive for improving intestinal health of piglets

The invention discloses an application of atractylodes macrocephala polysaccharide and pachymaran as a feed additive for improving intestinal health of piglets, which belongs to the field of the feedadditive. The application of atractylodes macrocephala polysaccharide and pachymaran as feed additive for improving intestinal health of piglets is characterized in that the appropriate addition amount accounts for 0.02%-0.08% of mass of a basic feed, the overhigh addition amount affect the growth performance, immunity and feed-to-weight ratio of the piglets, and the excessive low addition amountcannot achieve the effect; the atractylodes macrocephala polysaccharide and pachymaran is composed of atractylodes macrocephala polysaccharide and pachymaran according to a mass ratio of 1-2:1-2, thecontent of polysaccharides in atractylodes macrocephala polysaccharide and pachymaran is 37.5%; and the application of atractylodes macrocephala polysaccharide and pachymaran as the feed additive forimproving intestinal health of the piglets can effectively improve the intestinal barrier function of the early weaned piglets, improves the intestinal health of piglets, and can replace the antibiotics in promoting the growth performance of the piglets.
Owner:JIANGXI AGRICULTURAL UNIVERSITY

Method for promoting efficient water-soluble expression of arginine deiminase

ActiveCN103468664BPromote efficient water-soluble expressionOvercoming the drawbacks of poorly soluble expressionHydrolasesMicroorganism based processesPseudomonas putidaCitrulline
The invention discloses a method for promoting efficient water-soluble expression of arginine deiminase (ADI). The method comprises the following steps: connecting ADI gene derived from Pseudomonas putida with a pET-30a-c(+) carrier to construct a recombinant expression plasmid pET30a-ADI, and cotransforming the pET30a-ADI and pGro7 plasmid into E.coliBL21(DE3) to obtain double-plasmid-containing engineering bacteria; inoculating the engineering bacteria into an LB (Langmuir-Blodgett) culture medium containing 1-10 g / L D-glucose, adding L-arabinose, and culturing; and when the bacteria are cultured to a logarithmic phase, adding 1-10 g / L L-arginine and 0.1 mM IPTG (isopropyl-beta-D-thiogalactopyranoside), and carrying out induced culture at 16 DEG C under the condition of 180 rpm. The method disclosed by the invention can obviously enhance the water-soluble yield of the recombinant ADI protein, enhances the activity of the crude enzyme solution by 15 times, effectively overcomes the defect of difficulty in soluble expression of the recombinant ADI, provides technical support for application of industrialized large-scale production of citrulline and the like, and also provides a new idea for expression of other recombinant proteins.
Owner:SHANDONG UNIV

Medical pseudo holographic imager

A medical pseudo holographic imager comprises a main body; the main body comprises a rectangular pedestal, a developing table arranged above the rectangular pedestal, and a host; a development board is arranged in the host; projectors connected with the development board and matched in number with transparent boards are arranged in the host, and arranged in a projection reversal plate with the rotation angle controlled by the development board; a wifi module and a software operation platform are arranged in the development board; 3D figure browsing software is arranged in the software operation platform, and figures are respectively outputted to the 4 projectors through a video output module; at least one transparent board is covered by a touch screen; the input end of the touch screen isconnected with the development board. The medical pseudo holographic imager can directly demonstrate images, and doctors can conveniently explain conditions for patients, thus directly promoting validcommunications between doctors and patients, enabling patients and patient family members to understand conditions, making correct selections for the treatments, improving the medical teaching quality, allowing medical learners to directly understand the focus principles, and promoting the medical education for certain level.
Owner:余军辉

A method for co-processing coking desulfurization waste liquid, calcium-based solid waste and pollutants in industrial flue gas

The invention relates to a method for cooperative treatment of coking desulfurizing waste liquid, calcium-based solid waste and pollutants in industrial smoke. The method comprises the following steps: absorbing the oxidized industrial smoke by using absorbent slurry while controlling the pH of the slurry to 6 or higher during the absorption, wherein the absorbent slurry is a mixture of the calcium-based solid waste and the coking desulfurizing waste liquid; after the absorption, discharging the purified smoke, and performing solid-liquid separation on the absorbent slurry; performing impurityremoval and pH regulation on the obtained liquid phase, and heating for decomposition; performing solid-liquid separation to obtain an ammonium thiocyanate product. The method provided by the invention can realize efficient removal of sulfur dioxide, nitrogen oxide and mercury in smoke while recycling an ammonium thiocyanate product with high added value. The method provided by the invention canbe used for performing cooperative treatment on the waste gas, wastewater and waste residue generated in an industrial production process, has the advantages of simple process, low raw material cost and no wastewater discharge in the whole process, realizes cyclic economy of dealing with waste by waste, is suitable for industrial application and creates good economic benefits.
Owner:INST OF PROCESS ENG CHINESE ACAD OF SCI

A kind of scorpion venom heat-resistant synthetic peptide and use thereof

The invention discloses a scorpion venom heat-resistant synthetic peptide and its application, belonging to the field of polypeptide drug research and development. The polypeptide of the present invention is the amino acid sequence of the scorpion venom heat-resistant peptide (SVHRP) detected from the venom of the traditional Chinese medicine East Asian scorpion scorpion (BmK). A sample of the heat-resistant peptide extract from scorpion venom with pharmacodynamic activity of Alzheimer's disease (premature Alzheimer's disease) was separated by LaGM composite material and repeated rapid magnetic separation, and then performed parallel mass spectrometry using nanoliter reversed-phase chromatography-electrospray mass spectrometry (nanoLC-ESI-MS). A polypeptide sequence consisting of 15 amino acid residues was detected in the experiment; a heat-resistant synthetic peptide of scorpion venom was prepared through solid-phase chemical synthesis, chromatographic purification and mass spectrometry identification. Its amino acid sequence is shown in SEQIDNo 1, which maintains the The pharmacodynamic activity and safety of the scorpion venom heat-resistant peptide, and the bioactivity of the scorpion venom heat-resistant peptide also promotes the reverse differentiation of glial cells into neural stem cells.
Owner:上海万锦医药科技有限公司

Tipped fixed seat threading die with heat dissipation holes

The invention relates to the technical field of cutting-edge-embedded fixed seat screw dies, in particular to a cutting-edge-embedded fixed seat screw die with heat dissipation holes, and discloses a cutting-edge-embedded fixed seat screw die with the heat dissipation holes. Comprising a working table, mounting frames, top frames, a blade embedding device body, a blade, a placement groove, a fixed seat threading die body, a heat dissipation hole body, an operation groove, a fan, a flow guide pipe, a flow dividing pipe, a wind power flow guide plate, a rotating shaft, a connecting cylinder, dispersing fan blades and a sliding rod, the mounting frames are fixedly mounted on the two sides of the working table, and the top frames are fixedly mounted at the top ends of the two mounting frames; an inlaying device body is fixedly installed in the middle of the top end of the top frame. The fan runs to generate wind power, the wind power enters the operation groove through diversion and dispersion of the diversion pipe and the diversion pipe, a certain heat dissipation effect can be achieved on the fixed seat screw die body through penetration of the formed heat dissipation hole body, and therefore the fixed seat screw die body can dissipate heat in real time during running; and the problem of damage caused by too high heat is avoided.
Owner:东台市双厦工具有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products