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45 results about "Egg White Proteins" patented technology

According to the Egg Nutrition Center (ENC), the average egg contains about 6.29 grams of protein, 3.6 of which come from the egg white. In addition to proteins, other nutrients found in the egg white are riboflavin, niacin, folate, vitamin B12, calcium, iron, copper, zinc and sodium.

Low-digestibility animal protein-wheat flour composite noodles and preparation method thereof

PendingCN121890712AFood ingredient functionsBiotechnologyDigestible starch
The invention discloses low-digestibility animal protein-wheat flour composite noodles and a preparation method thereof, and belongs to the technical field of food processing. Wheat flour and exogenous animal protein are used as main raw materials, whey protein isolate, silkworm pupa protein, egg white protein and fish protein are selected, and the addition amount is 15% of the mass of the wheat flour. Through multi-index comprehensive screening, the silkworm pupa protein and whey protein isolate have better market development potential. By utilizing the synergistic effect of the exogenous animal protein and the wheat starch, the content of fast digestible starch (RDS) of the noodles can be remarkably reduced, the ratio of slow digestible starch (SDS) to resistant starch (RS) is increased, and the GI value of the noodles is lower than 70; meanwhile, cooking and texture characteristics are optimized, the cooking loss rate is smaller than or equal to 8%, and the breaking rate is smaller than or equal to 0.3%. The noodles have the characteristics of low glycemic content and high-quality eating taste, are balanced in nutrition, are suitable for diabetics to eat, can also be used as daily staple food of healthy people, and are simple and convenient in preparation process, easy to industrially produce and wide in market application prospect.
Owner:JILIN UNIVERSITY

Oleogel based on egg white protein, preparation of oleogel and application of oleogel in improving strength of Peru squid surimi gel

The invention discloses oleogel based on egg white protein, preparation of the oleogel and application of the oleogel in improving the gel strength of Peru squid surimi. The self-prepared egg white powder oleogel is added into the squid surimi as a fat analogue. Experiments prove that the squid surimi gel is beneficial to promoting the network structure of the surimi gel, so that the hardness of the surimi gel is increased, the water holding capacity is improved, the total concentration of flavor compounds is increased, the proportions of alcohols and aldehydes are reduced, and hydrocarbon and aromatic compounds are increased. The application of the oil gel as a fat substitute in the minced fillet gel has great potential. And healthy, low-fat and flavor-enhanced surimi gel products can be developed in the future.
Owner:ZHEJIANG GONGSHANG UNIVERSITY

A method for preparing a milky ready-to-drink egg white beverage using a complex enzyme preparation

The application belongs to the technical field of food processing, and more particularly relates to a method for preparing a milk-like instant egg white beverage by using a composite enzyme preparation. The method comprises the following steps: adding a composite enzyme preparation into egg white liquid, performing enzymatic hydrolysis treatment, adding a sweetening agent, an acidity regulator and a stabilizer after enzyme inactivation, uniformly mixing, obtaining a mixed liquid, performing homogenization treatment and ultra-high temperature instant sterilization treatment on the mixed liquid, and obtaining a milk-like instant egg white beverage; wherein the composite enzyme preparation comprises at least three of alkaline protease, papain, flavor protease and trypsin. The method of the application simplifies the production process, reduces energy consumption, and makes the product have excellent texture characteristics by directional enzymolysis of a specific composite enzyme preparation. The egg white protein content in the obtained product is greater than 90%, the product has a milk-like appearance, a delicate and smooth taste, and can be stored at room temperature for more than 6 months without separation or whey separation. The method of the application is simple in process, low in cost, excellent in product quality, and suitable for industrial production.
Owner:NINGXIA SUNSON IND GROUP CO LTD +3

Preparation and application of anti-sarcopenia albumin polypeptide gel beads

PendingCN122325553ADipeptidyl peptidaseDipeptide
The application belongs to the technical field of biotechnology, and particularly relates to application of albumin polypeptide gel beads in a product for treating or preventing sarcopenia. Egg white protein is used as raw material to extract protein, and albumin dipeptide-based peptidase-IV inhibitory peptide is prepared through a biological enzymolysis method. Bioinformatics analysis is used to screen out the inhibitory peptide TPYMFP, and the IC50 value of the inhibitory peptide TPYMFP for dipeptide-based peptidase-IV reaches 3.12 ± 0.49 mmol / L. Further, the optimal preparation conditions of sodium alginate SA and carboxymethyl chitosan CMCS-based gel beads CMCS / SA / TPYMFP are explored. When the SA concentration is 1.5% (w / v), the CMCS concentration is 0.5% (w / v), and the CaCl2 concentration is 1% (w / v), the polypeptide encapsulation rate is increased to 98.26% ± 0.25%. It is verified that the albumin polypeptide gel beads have good pH response characteristics, and efficient protection and intestinal target delivery of the sarcopenia inhibitory peptide are realized. The albumin polypeptide gel beads are applied to preparation of a product for treating or preventing sarcopenia, or in preparation of a related product for increasing muscle mass and strength.
Owner:BEIJING FORESTRY UNIVERSITY

Protein nanoparticle-nanofiber composite material and preparation method thereof

PendingCN121489066AProtein composition from eggsPeptide preparation methodsOligopeptideBiology
The invention discloses a protein nanoparticle-nanofiber composite material and a preparation method thereof, and belongs to the technical field of food processing and functional protein materials. The method comprises the following steps: (1) taking fresh egg white, diluting and stirring to obtain uniform egg white protein dispersion liquid; (2) performing acylation modification on the egg white protein dispersion liquid to increase surface negative charges and improve conformation flexibility; (3) performing controllable enzymolysis on the acylated egg white protein, so that part of peptide chains of the acylated egg white protein are broken and oligopeptide with self-assembly capability is formed; and (4) carrying out heat treatment on the enzymolysis product, inducing the peptide fragment to be self-assembled to form nano-particles while inactivating the protease through heat treatment, further forming a nano-fiber network dominated by a beta-folding structure, and finally obtaining the protein nano-particle-nano-fiber composite system. Through the synergistic effect of acylation, enzymolysis and heat treatment, accurate conversion of protein from a natural spherical conformation to a functional nanostructure is achieved, and the obtained composite material has the dispersion stability of particles and the network enhancement effect of fibers and has excellent foamability, emulsibility and gelling property.
Owner:HUAZHONG AGRI UNIV

Egg white protein nanogel as well as preparation method and application thereof

PendingCN121926271AFood thermal treatmentFood ingredient as foaming agentUltrasonic cavitationProtein structure
The invention discloses a preparation method of egg white protein nanogel. The preparation method comprises the following steps: firstly, adding an ethanol solution with the volume fraction of 0.1-11.5% into egg white liquid, and diluting until the protein concentration is 1-2%; the egg white protein ethanol solution is subjected to microwave and ultrasonic combined treatment, the treatment time is set to be 3-7 min, ultrasonic is in an intermittent mode, the ultrasonic power is 200-800 W, and the microwave heating temperature is 65-75 DEG C. And finally, removing ethanol in the solution subjected to microwave ultrasonic treatment to obtain the egg white protein nanogel particles. The method is different from an existing'bottom-to-top 'preparation method and comprises the following steps: firstly, carrying out mild denaturation on protein by adopting low-concentration ethanol, changing a protein structure and an intermolecular acting force to expose a hydrophobic structure and expand the structure, and then moderately gathering and crushing the protein into microgel by utilizing an ultrasonic cavitation effect and a microwave heat effect; the nanogel has smaller particle size, higher system stability and interface stability, and the preparation method is simple and low in cost.
Owner:QINGDAO HOTEL MANAGEMENT VOCATIONAL & TECH COLLEGE

Egg white-chlorella composite protein gel and application thereof in preparation of dysphagia adaptive food

The application belongs to the technical field of food processing, and particularly relates to egg white-chlorella compound protein gel and application thereof in preparation of dysphagia adaptive food. The application provides an egg white-chlorella compound protein gel, which is obtained by heating and cross-linking of egg white protein and chlorella protein dispersed in water. The gel has high protein density (protein content is greater than or equal to 12 w / w %) and low hardness (<120 g), and its swallowing adaptability meets the international dysphagia diet standardization initiative (IDDSI) 3-5 solid food standard, so that the eating needs of patients with moderate to severe dysphagia who cannot independently control liquid intake can be met, and a new food option with high nutritional density and excellent swallowing safety is provided for the patients, so that the nutritional status of the patients can be effectively improved and the life quality of the patients can be improved.
Owner:HUIZHOU MILAIMI FOOD CO LTD +2

Bitterless and high-stability egg white source protein polypeptide as well as preparation method and application thereof

The invention discloses a bitter-free high-stability egg white source protein polypeptide and a preparation method and application thereof, and the preparation method of the protein polypeptide comprises the following steps: S1, emulsification: adding an emulsifier into an egg white solution, and carrying out homogeneous emulsification to obtain an emulsion; s2, hydrolysis: preheating the emulsion, adding hydrolase into the preheated emulsion, and hydrolyzing at 30-60 DEG C for 3-8 hours to obtain hydrolysate; s3, enzymolysis: adding flavourzyme into the hydrolysate, carrying out enzymolysis at 30-60 DEG C for 0.5-4 hours, and cooling, so as to obtain an egg white protein liquid enzymolysis product. According to the preparation method provided by the invention, the thermal stability of the egg white source protein polypeptide is remarkably improved, and bitter taste caused by hydrolysis is effectively removed by adding flavourzyme for enzymolysis. The protein polypeptide prepared by the invention has a good application prospect in preparation of protein polypeptide products.
Owner:李宪臻

Preparation method of antibacterial mildew-proof coating for inner wall of sterile bottle

The invention discloses a preparation method of an antibacterial and mildew-proof coating for the inner wall of a sterile bottle, which comprises the following steps: thoroughly cleaning and disinfecting the sterile bottle through ultrasonic cleaning and high-temperature steam sterilization to ensure that no microbial residue exists in the bottle; activating the inner wall of the bottle by adopting a plasma cleaning machine; then, polylactic acid modified ovalbumin is dissolved in water, a glutamine transaminase cross-linking agent and a chitosan polymer are sequentially added to prepare a modified protein solution, and the mixture not only has excellent biocompatibility and antibacterial performance, but also can effectively prevent bacteria and mould from breeding; filtering the prepared solution, injecting the filtered solution into an activated sterile bottle, uniformly covering the inner wall of the bottle with the solution by using a spin coater, and carrying out curing treatment in a constant-temperature oven to finally form an antibacterial and mildew-proof coating; according to the method, the toxicity problem caused by chemical additives is avoided, meanwhile, the stability and durability of the coating are improved, the service life of the sterile bottle is greatly prolonged, and the protection performance of the sterile bottle is enhanced.
Owner:JIANGSU HUAJING MOLECULAR IMAGING & DRUG RES INST CO LTD

Heat coagulation gel strength regulating agent for egg white protein

ActiveUS12616231B2HydrolasesFood scienceBiotechnologyEgg White Proteins
The purpose of the present invention is to provide a technology that enables control for increasing or decreasing the heat coagulation gel strength of egg white protein, and that has little effect on taste. This heat coagulation gel strength regulating agent for egg white protein contains a protein deamidase and can control the increase or decrease of the heat coagulation gel strength of egg white protein.
Owner:AMANO ENZYME INC

Flexible amyloid fiber gel based on albumin and lysozyme as well as preparation method and application of flexible amyloid fiber gel

The invention discloses flexible amyloid fiber gel based on albumin and lysozyme as well as a preparation method and application of the flexible amyloid fiber gel, and belongs to the field of delivery of natural high polymer materials and bioactive substances. The method comprises the following steps: respectively preparing ovalbumin fibers (OVAf) and lysozyme fibers (LYZf), mixing according to a volume ratio of 2: 1, adding resveratrol with a final concentration of 100 [mu] mol / L, and incubating at 37 DEG C for 3 h to form flexible gel; according to the gel, ordered crosslinking of fibers is induced through resveratrol, a uniform three-dimensional network is formed, and the gel has good elasticity and flexibility; when being used as a carrier to embed active ingredients such as anthocyanin, the nano-carrier can significantly improve the storage stability and digestion environment tolerance, and has excellent biocompatibility. The invention provides a new scheme for efficient delivery of bioactive components, and can be applied to the fields of functional foods, biological medicines and the like.
Owner:SHAANXI UNIV OF CHINESE MEDICINE

An egg white protein loaded nitro radical nitrogen oxide nanocomposite material, a preparation method and application thereof

The application discloses an egg white loaded nitro radical nitrogen oxide nanocomposite material and a preparation method and application thereof, and belongs to the technical field of material preparation. The nitro radical nitrogen oxide nanocomposite material is regular in shape, has an average particle size of 100nm-150nm, and has good dispersibility. The preparation method is as follows: chitosan and tetramethylpiperidine-nitrogen oxide are respectively dissolved in water and dichloromethane or dimethyl sulfoxide, the two are mixed after stirring and complete dissolution, dialysis is performed after reaction, the material is washed with ultrapure water, centrifuged, and dispersed in ultrapure water after dialysis. In addition, the egg white is loaded on the nitro radical nitrogen oxide nanocomposite material, so that the nanomaterial is endowed with immunogenicity. The material prepared by the method has a magnetic resonance imaging enhancement effect and potential as an immunoadjuvant.
Owner:ZHEJIANG SCI-TECH UNIV

Egg white peptide capable of improving immunity activity as well as preparation method and application of egg white peptide

The invention discloses an egg white peptide for improving immunity activity as well as a preparation method and application thereof, and belongs to the technical field of bioactive peptides. The preparation method comprises the following steps: preparing egg white protein powder by taking egg white as a raw material and adopting an alkali extraction and acid precipitation method; alkaline protease immobilized by the alginate-based carrier is used for enzymolysis, and the immobilized enzyme can be repeatedly used and is high in efficiency and low in cost; and sequentially carrying out ultrafiltration separation and DEAE-52 cellulose ion exchange chromatography purification on the enzymatic hydrolysate, and precisely screening out high-activity components in combination with immunocompetence tracking. The molecular weight of the obtained egg white peptide is mainly distributed below 1 kDa, the purity reaches 92% or above, and the egg white peptide has definite good water solubility, is easy to absorb and has immunological enhancement activity. The egg white peptide can be used for preparing health-care food, formula food for special medical purposes and the like, high-value utilization of egg white resources is achieved, and the application prospect is wide.
Owner:SHANXI NANBA BIOTECHNOLOGY CO LTD

A method for preparing a fat substitute using a pediococcus acidilactici exopolysaccharide

The application discloses a method for preparing a fat substitute by using Pediococcus acidilactici S1 exopolysaccharide, and belongs to the technical field of fat substitute preparation, and specifically comprises the following steps: freezing and drying egg white powder and Pediococcus acidilactici S1 exopolysaccharide, then dissolving and mixing the two kinds of freeze-dried powder, and water-bath heating to induce the formation of Pediococcus acidilactici S1 exopolysaccharide-egg white protein gel. The Pediococcus acidilactici S1 exopolysaccharide-egg white protein gel is very similar to the texture of animal fat, and can be used as a fat substitute of animal fat. After the animal fat is replaced by the fat substitute in equal amount, the taste and texture of the prepared sausage product are basically completely the same as those of the original sausage product. The health degree is significantly improved. The healthy polysaccharide product is used to replace the animal fat. The fat substitute is not easy to be oxidized and has environmental stability, and has physiological activities such as anti-tumor, improvement of intestinal microecology of human bodies, anti-biofilm, adsorption of soluble heavy metals, and the like, and meets the requirements of current healthy food.
Owner:ANHUI AGRICULTURAL UNIVERSITY

Egg white protein source peptide capable of improving malnutrition and enhancing immunity and application of egg white protein source peptide

The invention discloses an egg white protein source peptide capable of improving malnutrition and enhancing immunity and application of the egg white protein source peptide, and belongs to the technical field of small molecule peptides. Alkaline protease, papain and neutral protease are sequentially used for carrying out enzymolysis on egg white protein to prepare egg white protein peptide, wherein the egg white protein peptide contains tripeptide LPR with an immunity enhancing effect. Animal model function verification shows that the egg white protein peptide containing the tripeptide LPR can remarkably improve the levels of total protein, albumin, prealbumin and globulin in serum and the content of short-chain fatty acid in intestinal tracts, and the effect of improving malnutrition is achieved. The food-borne bioactive peptide is high in biological safety. Therefore, the tripeptide LPR or the egg white protein peptide containing the peptide fragment can be applied to preparation of medicines or health-care foods for improving malnutrition and enhancing immunity. The invention provides a theoretical support basis for the efficacy of the egg white protein peptide in the aspect of improving malnutrition.
Owner:HANGZHOU KANGYUAN FOOD SCI & TECH +1

Stem cell egg powder derived from fertilized eggs as well as preparation method and application of stem cell egg powder

The invention relates to the technical field of egg white protein extraction, and discloses stem cell egg powder derived from fertilized eggs and a preparation method and application of the stem cell egg powder. According to the method, a specific low-temperature graded salting-out path is constructed, impurities such as ovomucin are selectively removed through the first-stage sodium sulfate precipitation, the purity of the extract is improved, the purity of the extract is improved, and the purity of the extract is improved. And a clean solution background is created for the second-stage sodium chloride precipitation, so that the unification of high-activity retention and high-purity separation of the target active protein is realized under low-temperature operation in the whole process.
Owner:曹凌杰

An egg white protein-containing gel and preparation and use thereof

PendingCN122536646ABiotechnologyNutrition
This invention belongs to the field of food processing and protein gelation technology, specifically relating to an ovalbumin-containing gel and its preparation and application. The method involves gelling an ovalbumin-containing sample at 45℃~60℃ through the synergistic effect of acidic pH and salt ions, obtaining an ovalbumin-containing gel; wherein the salt ions are cations capable of forming solvent-sharing ion pairs with ovalbumin. Furthermore, by controlling the conditions, a transparent gel can be obtained. Under the synergistic effect of acidity and salt ions, ovalbumin can form a gel at a minimum temperature of 45℃, far lower than the traditional gelation temperature. This low-temperature condition significantly saves energy and avoids the damage to protein nutrition and flavor caused by high temperatures; furthermore, this invention applies low-temperature induced ovalbumin gelation technology to the rapid pickling of shell-bound eggs. The egg white is translucent and smooth, without an alkaline taste, and has a moderate salt content. By adjusting the pH and ion concentration of the pickling solution, the hardness, elasticity, and transparency of the egg white gel can be precisely controlled, achieving standardized production.
Owner:QINGDAO UNIV

Synthetic controls for immunohistochemistry

To provide reliable positive and negative IHC controls that are highly sensitive, specific, and adaptable to a wide range of targets, including targets for which no suitable biological controls exist.SOLUTION: Synthetic controls include a solid antigen / carrier protein gel comprising purified antigen (e.g., in a known amount) and a carrier protein, such as a serum albumin protein (e.g., a serum albumin protein), an egg white protein or a mixture of egg white proteins, gelatin, or polylysine. In some embodiments, the purified antigen is cross-linked to a carrier protein in a solid antigen / carrier protein gel.SELECTED DRAWING: Figure 3-1
Owner:GENENTECH INC

A method and apparatus for increasing the resistant starch content of wheat flour

This invention discloses a processing method and equipment for increasing the resistant starch content in wheat flour, relating to the field of resistant starch production technology. The processing method includes steps such as mixing, stirring, forming, drying, and milling raw materials such as egg white protein powder. The equipment includes a multi-layered mixing device, a stirring chamber, a forming chamber, a drying chamber, and a milling chamber arranged from top to bottom. The multi-layered mixing device includes a tank containing multiple layers of stirrers, a feed pipe on the left side of the tank, and multiple nozzle groups on the right side wall of the tank. The stirring chamber contains a temperature control device and stirrers. The forming chamber contains two forming rollers rotating in opposite directions. The drying chamber contains two drying rollers. The milling chamber contains a pulverizer. This invention's method for preparing wheat flour rich in resistant starch by adding raw materials such as egg white protein powder has the advantages of readily available raw materials, simple operation, large processing capacity, and high resistant starch conversion rate.
Owner:WUHAN POLYTECHNIC UNIVERSITY

Property modifier for heat-coagulated gel of egg white protein

PendingEP4470387A4HydrolasesProteins working-up by texturisingEgg White ProteinsHeat coagulation
The purpose of the present invention is to provide a novel technology for modifying the properties of the heat-coagulated gel of egg white protein. In the present invention, a composition containing soy protein that has been subjected to protein deamidation is capable of improving the hardness, resiliency, and / or water-holding capacity of the heat-coagulated gel of egg white protein.
Owner:AMANO ENZYME INC

A medium for insemination of goldfish and a method for artificial insemination and hatching of goldfish

The present application belongs to the technical field of aquaculture, and particularly relates to a goldfish insemination medium and a method for artificial insemination and hatching of goldfish. The specific implementation steps are as follows: selecting female and male parent fish which are in the process of tail chasing reproduction, squeezing the abdomen of the fish to discharge the eggs and sperm into the insemination medium, and stirring and mixing the artificial insemination; transferring the eggs to a mucus removal medium to remove the mucus of the eggs; placing the mucus-removed eggs into a hatching bag after simple rinsing; and transferring the hatched fry into a rearing pond for feeding. The suitable osmotic pressure and egg white protein environment provided by the insemination medium can significantly prolong the duration of the activity of goldfish eggs and sperm, and improve the effect of increasing the fertilization rate of the eggs; the mucus removal medium is used to remove the mucus of the eggs, so as to avoid the mutual adhesion of the eggs into groups or clusters, improve the hatching rate of the goldfish, and enable the hereditary ornamental traits of the goldfish to fully develop, while preventing pathogenic microorganisms from being transmitted from the parent generation to the offspring generation. The selection of the hatching bag provides a good hatching environment for the eggs.
Owner:PEKING UNIV

Preparation method and application of novel egg white protein muscle building powder

PendingCN121795623AProtein composition from eggsPeptide preparation methodsBiotechnologyUltrafiltration
The invention relates to a preparation method and application of novel egg white protein muscle building powder, and provides high-quality nutrition support for improving muscle quality. The method takes fresh egg white as a raw material; a finished product is prepared through the steps of egg white separation after eggshell disinfection, ultrasonic-shearing synergetic flocculation removal, yeast beta glucan-polyphenol composite microsphere live protection system addition, acid-dynamic high-pressure microjet low-temperature pretreatment, compound protease enzymolysis, ultrafiltration impurity removal, gradient pH membrane separation and purification, low-temperature vacuum spray drying and the like. The composite microspheres are adopted to replace chemical protecting groups, and the whole-course low-temperature processing technology is combined, so that the activity of branched chain amino acid is effectively maintained. The protein powder can prolong the exercise exhaustion time of mice with muscle injury, improve the muscle repair efficiency, and realize the dual functions of muscle-building nutrition and oxidation resistance. The product adapts to various food systems, and can be widely applied to the fields of sports nutrition and food for special medical purposes.
Owner:ANHUI RONGDA FOOD CO LTD

Preparation method of low-salt minced spanish mackerel gel based on egg white protein

The invention discloses a preparation method of low-salt minced spanish mackerel gel based on egg white protein, and belongs to the field of food processing. The preparation method comprises the following steps: S1, blending spanish mackerel to obtain minced spanish mackerel meat; s2, adding salt into the minced spanish mackerel meat, and blending to obtain low-salt minced spanish mackerel meat; s3, egg white protein is added into the low-salt minced spanish mackerel for blending, and low-salt egg white protein-minced spanish mackerel is obtained; and S4, performing two-stage heating on the low-salt egg white protein-minced spanish mackerel fillet to obtain the low-salt minced spanish mackerel fillet gel. According to the preparation method disclosed by the invention, the egg white protein is used for replacing spanish mackerel protein, so that the texture property of the low-salt minced spanish mackerel gel is improved, the indexes such as gel strength, water binding capacity and cooking loss of the low-salt minced spanish mackerel gel are ideal, and the network structure is more uniform and compact.
Owner:DALIAN POLYTECHNIC UNIVERSITY

Micromolecular ovalbumin peptide with effects of improving exercise tolerance and relieving oxidative stress and preparation method thereof

The invention discloses a micromolecular ovalbumin peptide with effects of improving exercise tolerance and relieving oxidative stress and a preparation method of the micromolecular ovalbumin peptide, and belongs to the technical field of functional protein peptide preparation. The preparation method of the micromolecular ovalbumin peptide comprises the following steps: taking egg white protein, carrying out heat treatment and centrifugation, collecting supernate, adding a compound enzyme preparation for enzymolysis, carrying out plate frame filtration, adjusting the pH value to 5.5-7.0 and the salt content to be less than or equal to 0.1 mol L <-1 >, loading and adsorbing by using non-polar macroporous resin, washing by using pure water which is 1-2 times of the volume of the resin after the loading is finished, and drying to obtain the micromolecular ovalbumin peptide. Eluting by using a 10%-30% ethanol solution, and collecting an eluent; and performing concentration, solvent removal, desalination and drying on the eluent by using a nanofiltration unit to obtain the micromolecular ovalbumin peptide. The small molecule peptide has high antioxidant activity, and can realize the triple effects of immediate absorption, rapid antioxidation and synchronous anti-inflammation; and the preparation process is simple, and industrial mass production can be realized.
Owner:JIANGNAN UNIV +1

Preparation method of tetravalent influenza virus split vaccine

The invention relates to the technical field of biological medicine and vaccine preparation, and discloses a preparation method of a tetravalent influenza virus split vaccine, and the preparation method comprises the following steps: inoculating four influenza viruses into a chick embryo, culturing, harvesting allantoic fluid, and concentrating; centrifugally purifying through a sucrose density zone, and adding a cracking agent for cracking; removing the cracking agent from the cracking solution through chromatographic column chromatography, and then adding an inactivating agent for inactivating and removing the inactivating agent; according to the method disclosed by the invention, a process route of firstly splitting purification and then inactivation in combination with dual purification of centrifugation and chromatography is adopted, so that the problem of impurity cross-linking caused by an inactivator in a traditional process is effectively avoided, and residues of ovalbumin and splitting agents are deeply removed; and the natural conformation of the virus antigen is retained to the greatest extent. The obtained vaccine is extremely low in impurity content, has excellent safety and high immunogenicity, and can effectively expand the immune protection range and enhance the population immune barrier.
Owner:CHANGCHUN INST OF BIOLOGICAL PRODS

Albumin postbiotic peptide and its use in the preparation of a medicament for the relief or treatment of food allergy

The application discloses an albumin postbiotic peptide and application thereof in preparation of a medicine for relieving or treating food allergy, and belongs to the technical field of bioactive peptides. The albumin postbiotic peptide is prepared from egg white protein powder through enzymolysis, inoculation of fermentation lactobacillus mucus IOB802, fermentation and inactivation again. The polysaccharide content in the albumin postbiotic peptide is as high as 1860.74 mg / 100g, the albumin postbiotic peptide can regulate immune balance, reduce allergy-related factors such as IgE and IL-4 and histamine level, increase IgG2a antibody level, reduce infiltration of eosinophils and mast cells in jejunum tissue, down-regulate expression of proinflammatory factors such as IL-25 and TSLP, up-regulate tight junction proteins such as ZO-1 and Occludin, repair intestinal barrier, block penetration of allergens and relieve food allergy symptoms.
Owner:TIANJIN INNOORIGIN BIOLOGICAL TECH CO LTD

Baricitinib tablet and preparation method thereof

The application relates to the technical field of medicines, and particularly discloses a baricitinib tablet and a preparation method thereof. The baricitinib tablet comprises a tablet core and a coating film, the tablet core is obtained by tabletting core materials, the coating film is formed by solidifying a coating liquid, and the components of the coating liquid comprise hydroxypropyl methyl cellulose, medical-grade polyacrylic acid resin, egg white protein and water. Compared with a single-component hydroxypropyl methyl cellulose coating film, the coating film can make a greater contribution to the hardness of the baricitinib tablet, and is helpful to overcome the adverse effect of microcrystalline cellulose on the hardness of the baricitinib tablet. By adopting the technical scheme, a tablet product with relatively high hardness can be produced by using relatively poor microcrystalline cellulose, the requirement of a tablet production process on raw materials is reduced, and full use of the microcrystalline cellulose is facilitated.
Owner:NANJING ZENKOM PHARMA

Preparation and activity protection method of egg white protein peptide with high antioxidant activity

The invention discloses a preparation and activity protection method of egg white protein peptide with high antioxidant activity, which comprises the following steps: taking egg white liquid as a raw material, adding deionized water to prepare a protein suspension, stirring and uniformly mixing in an ultrasonic water bath, and cooling to room temperature to obtain denatured protein liquid; sequentially adding incision enzyme, excision enzyme and flavourzyme into the denatured protein liquid to carry out synergistic directional enzymolysis; centrifuging the mixed solution after enzymolysis, taking supernate, performing ultrafiltration on the supernate, and collecting filtrate; performing ultrasonic mixing on the filtrate and the composite protective solution, performing high-pressure homogenization, and performing spray drying to form microcapsule particles; and adding a freeze-drying protective agent into the prepared microcapsule particles, and freeze-drying to obtain the finished product of the egg white protein peptide with high antioxidant activity. The method has the remarkable effects that the antioxidant index of the prepared egg white peptide is remarkably higher than that of an egg white peptide product reported in the prior art or a traditional antioxidant, and the egg white peptide has good product stability.
Owner:ZHEJIANG UNIV OF SCI & TECH

Egg white protein-derived small molecule peptide with the functions of regulating immunity, tonifying qi and blood and uses thereof

The application discloses egg white protein source small molecule peptides with the functions of regulating immunity and tonifying qi and blood and application thereof, and belongs to the technical field of small molecule peptides. The application uses alkaline protease, papain and neutral protease to sequentially perform enzymolysis on egg white protein to obtain egg white small molecule peptides containing dipeptide LW. Animal model function verification shows that the dipeptide LW and the egg white small molecule peptides containing the peptide segment have the function of improving qi and blood deficiency, and high-dose (converted into 3.0g / 60kg.d for an adult) egg white small molecule peptides increase red blood cells, hemoglobin, platelets and lymphocytes by 16.6%, 14.7%, 23.4% and 28.75% respectively. Food-derived bioactive peptides have high biological safety, and therefore, the dipeptide LW and the egg white small molecule peptides containing the peptide segment can be applied to the preparation of medicines with the functions of regulating immunity and improving qi and blood, and have good market prospects and application potential.
Owner:HANGZHOU KANGYUAN FOOD SCI & TECH +1

Making method of convenient crisp deep-fried dough sticks

PendingCN121713993ADough treatmentProtein composition from eggsBiotechnologyEngineering
The invention discloses a making method of convenient crisp deep-fried dough sticks, and belongs to the field of deep-fried products. According to the method, the soybean protein isolate solution and the egg white protein solution are prepared and compounded to serve as dispersion phases to prepare the gel-like emulsion with the oil phase being 60%-80%, the freezing resistance of the gel-like emulsion is improved, and the compounded gel-like emulsion serves as a leavening agent to be added into dough. The making method of the fried bread sticks is green, the oil content and the oil oxidation degree of the fried bread sticks are reduced, the operation efficiency and convenience are improved, the color and luster of the fried bread sticks can be effectively regulated and controlled, and technical innovation and quality improvement in the field of fried foods are expected to be promoted.
Owner:DALIAN POLYTECHNIC UNIVERSITY