34results about How to "Mild degradation conditions" patented technology

The invention discloses a method for preparing a monophenol compound through catalyzing degradation of lignin by using an ammino-complex. The method comprises the steps: adding the lignin, a metal salt, ammonia water, a peroxidant, an alkali and deionized water into a high-pressure reaction vessel, and carrying out stirring to form a uniform solution; carrying out a reaction for 100 to 240 minutes at the temperature of 120 DEG C to 180 DEG C, and carrying out cooling; and adjusting the pH value of a reaction solution to 2 to 3 with an acid, then, carrying out a reaction for 10 to 20 minutes at the temperature of 100 DEG C to 120 DEG C, carrying out cooling, then, carrying out filtration to collect filtrate, carrying out extraction on the filtrate with dichloromethane, separating an organic phase, and carrying out drying with anhydrous calcium chloride, thereby obtaining a monophenol compound mixed solution. According to the method, a stable ammino-complex solution is formed by using the metal salt and the ammonia water under alkaline conditions, so that the number of sites of contact between a catalyst and the lignin can be effectively increased compared with that in the conventional lignin oxidative degradation method; the degradation of the lignin can be efficiently catalyzed in an aqueous solution under moderate reaction conditions; and the method has the characteristics of high efficiency and low cost and is applicable to large-scale industrial production.

The invention discloses a method for removing residual pharmaceutical ingredients in oxytetracycline pharmaceutical dregs by ultrasonic wave, comprising the following steps of: A, heating up oxytetracycline wet pharmaceutical dregs to solidify protein, so that the protein is not influenced by ultrasonic wave; B, cooling the oxytetracycline wet pharmaceutical dregs into normal temperature, adjusting the pH of the oxytetracycline wet pharmaceutical dregs into 0.5-1.0 by hydrochloric acid, and evenly stirring the wet pharmaceutical dregs; and C, putting the evenly-stirred wet pharmaceutical dregs into a container with normal pressure and ultrasonic environment to carry out ultrasonic wave radiation, and degrading and invalidating the oxytetracycline ingredient in the wet pharmaceutical dregs by the acoustic cavitation effect of the ultrasonic wave. The method is quick, low-cost and environment-friendly to treat the oxytetracycline pharmaceutical dregs, and is good in treatment effect, so that the obtained product is heavy in weight and high in use value.

The invention provides four preparation methods of degradable primary amine curing agents, including the reaction of raw materials and ammonia or ammonia water to generate primary amine curing agents, and the raw materials undergo Gabriel reaction to generate o-(benzene) dicarboximide groups The compound, and then the compound is hydrolyzed or hydrazinolyzed to obtain a crude product, and then the crude product is purified to obtain a primary amine curing agent. The epoxy resin and the fiber-reinforced composite material prepared by the primary amine curing agent obtained by the method have good degradation performance, are environmentally friendly, and belong to green environmental protection materials.

The invention belongs to the field of medicine, and relates to a method for degrading chondroitin sulfate and hyaluronic acid to obtain chondroitin sulfate disaccharide and hyaluronic acid disaccharide and detecting the chondroitin sulfate disaccharide and the hyaluronic acid disaccharide. The method comprises the following steps: (1) deacetylating chondroitin sulfate or the hyaluronic acid to obtain a deacetylation product; (2) performing degradation on the deacetylation product, namely nitrite, to obtain chondroitin sulfate disaccharide or hyaluronic acid disaccharide; (3) completely concentrating disaccharide, dissolving disaccharide in water, regulating the pH value as alkaline, adding pyrazolone derivatization reagents, and after reaction is completed, performing three times of extraction through chloroform to remove redundant derivatization reagents; (4) detecting the derived disaccharide through LC (liquid chromatography) or LC-MS (liquid chromatography-mass spectrometry). According to a chemical degradation method, chondroitin sulfate or hyaluronic acid can be completely degraded as the disaccharide, all pieces of uronic acid information can be stored, the degradation condition is mild, the cost is low, the operation is easy, the requirement on experiment instruments can be met, consumed detection time is short, the sample consumption is low, the sensitivity is high and the analysis result repeatability is good.

The invention relates to a degradation method for treating phenolic wastewater by ultrasonic collaborative pulse electric field. The degradation method comprises the steps of: adding sodium salt or potassium salt electrolyte into the phenolic wastewater to be degraded, and adjusting the pH value to be 4-10 by using acid or alkali; putting electrodes into the phenolic wastewater, wherein the distances among the electrodes are within the range of 10-35mm, and controlling the constant voltage of a pulsed power supply to be 8-12V and the pulse period to be 0.1-10ms; inserting an ultrasonic head into the phenolic wastewater, and adjusting the ultrasonic output power to be 50-900W and the frequency to be 20-25kHz, the ultrasonic time to be 0.5-10s and the interval time to be 0.5-10s; and then, starting ultrasonic wave and the pulse electric field for degradation. The degradation efficiency of phenol is improved by the synergistic effect of the ultrasonic wave and the pulse electric field; and under the same pulse electric field, the degradation rate is obviously increased compared with the pure pulse electric field or ultrasonic field. The degradation method is simple in operation, the electrodes used by the method are low in cost and easily obtained, the phenol can be completely degraded, and the degradation process is safe and environment-friendly.

The invention discloses Bacillus genus D7 and its application in degrading cellulose. The strain of the invention can degrade sodium carboxymethyl cellulose (CMC-Na), cellulose of water extraction residue of waste inferior tobacco leaves and Cellulose materials such as tobacco leaves and stems, and the cellulase produced by the bacteria has the characteristics of high temperature resistance of 60°C and a wide range of catalytic substrate pH4-8. It has tolerance; compared with physicochemical and mechanical methods to degrade cellulose, the degradation conditions of the bacteria are milder; compared with fungi, bacteria have stronger reproductive ability, are easy to cultivate, and can be gradually enlarged, and industrial applications are expected to be realized in the later stage; The bacterial species of cellulase include Bacillus amyloliquefaciens, Clostridium thermobacterium, Paenibacillus and the like.

The invention discloses a preparation method of a bamboo liquid-collagen polypeptide composite adhesive. The preparation method comprises the following steps of: step (1). putting bamboo powder into alkali liquor in a reaction kettle, and performing primary alkali thermal degradation reaction to obtain bamboo liquid; step (2). adding leather meal to the bamboo liquid in the reaction kettle, and performing secondary alkali thermal degradation reaction on the leather meal to obtain bamboo liquid-collagen mixed degradation liquid; step (3). performing mechanical filter pressing on the bamboo liquid-collagen mixed degradation liquid to collect filtrate; and step (4). adjusting the pH of the filtrate, adding a crosslinking agent and a plasticizer, stirring and reacting to obtain the bamboo liquid-collagen polypeptide composite adhesive. The preparation method of the bamboo liquid-collagen polypeptide composite adhesive utilizes biomass resources and has low production cost.

The invention belongs to the field of medicine, and relates to a method for degrading heparan sulfate and detecting heparan sulfate disaccharide composition. The method comprises the following steps of (1) degrading heparan sulfate into disaccharide by utilizing a chemical degradation method; (2) deriving the heparan sulfate disaccharide by utilizing a derivation reagent; (3) detecting the derived heparan sulfate disaccharide obtained in the step (2) by utilizing the liquid chromatography (LC) or liquid chromatography-mass spectrography (LC-MS) method. The heparan sulfate can be completely degraded into the disaccharide through the two chemical degradation methods, so that the structural information of the heparan sulfate disaccharide can be maximally obtained. The degradation condition is moderate, the cost is low, simplicity in operation can be realized, the requirement on the experimental instruments is low, the application range is wide, the detection time is short, the consumption of samples is small, the sensitivity is high, and the repeatability of the analysis result is good.

The invention relates to an ultra-low molecular weight heparin sodium and a preparation method thereof, belonging to the field of biomedicine. Through membrane separation, the low molecular weight heparin sodium is further degraded into heparin fragments. The preparation method has mild degradation conditions, can reduce the detachment of the sulfonic acid group from the heparin, and can realize that almost all the raw materials of the heparin sodium are depolymerized into the ultra-low molecular weight heparin sodium. The ultra-low molecular weight heparin sodium prepared by this method has a high yield, an average molecular weight of less than 3000 Da, and a higher anti-Fxa biological activity.